Clinical trials: Insulin Pump
Type 1 Diabetes Mellitus
The International Diabetes Closed Loop (iDCL) Trial: Clinical Acceptance of the Artificial Pancreas
The objective of the study is to assess efficacy and safety of a closed loop system (t:slim X2 with Control-IQ Technology) in a large randomized controlled trial.
- Trial name
- DCLP3 (NCT03563313)
- Testing
- t:slim X2 with Control-IQ Technology & Dexcom G6 CGM, Sensor-augmented pump (SAP)
- Where
- 7 sites in United States
- Volunteers
- 168 people
- Sponsor
- University of Virginia
Type 1 Diabetes
Hybrid Closed-Loop Control With Smart Prandial Insulin Dosing in Type 1 Diabetes
The objective of this study is to evaluate the safety and feasibility of a smart bolus calculator that adjusts insulin dosing for meals according to real-time insulin sensitivity (SI) in adolescents with type 1 diabetes (T1D)…
- Trial name
- NCT04878120
- Testing
- Standard HCL System, HCL System with Smart Bolus Calculator
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Virginia
Type 1 Diabetes
Expanding Coverage of Continuous Subcutaneous Insulin Infusion in Pediatric Patients With Diabetes
The purpose of the study is to present evidence based literature and clinical data to the medical directors at Missouri Medicaid to help modify the existing policy regarding insulin pump therapy in pediatric patients with…
- Trial name
- NCT00829062
- Testing
- Continuous glucose glucose sensor- physician ordered
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Diabetes Mellitus, Type 1
Management of Glycemia Following a Pizza Meal
Glycemia following pizza consumption is typically managed with a dual wave insulin bolus. This study evaluated the effect of a simple bolus on glycemia following consumption of traditionally prepared pizzas with long (22 hours)…
- Trial name
- NCT03748251
- Testing
- the patients ate a pizza that fermented for 8 hours, the patients ate a pizza that fermented for 24 hours
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- University of Campania Luigi Vanvitelli
Diabetes Mellitus, Diabetes Mellitus, Type 1
Day and Night Closed-loop in Young People With Type 1 Diabetes
The main study objective is to determine whether 24/7 automated closed-loop glucose control combined with low glucose feature will improve glucose control as measured by HbA1c.
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders, Endocrine System Diseases
- Trial name
- DAN05 (NCT02925299)
- Testing
- FlorenceM (US) and FlorenceX (UK), Insulin pump therapy
- Where
- 11 sites in United States, United Kingdom
- Volunteers
- 133 people
- Sponsor
- Jaeb Center for Health Research
Type 1 Diabetes Mellitus
The Artificial Pancreas in Very Young Children With T1D
The suggested clinical trial is part of the KidsAP project funded by the European Commission's Horizon 2020 Framework Programme and JDRF.
- Trial name
- KidsAP02 (NCT03784027)
- Testing
- CamAPS FX, Sensor augmented therapy
- Where
- 8 sites in Austria, Germany and 2 more
- Volunteers
- 81 people
- Sponsor
- University of Cambridge
Biomedical Technology, Type 1 Diabetes
Analysis of Glycemic Control in Type 1 Diabetes Patients Using Hybrid Closed Loop Insulin Pump Therapy (Medtronic 670G)
Observational study of patients at Boston Childrens Hospital with type 1 diabetes (T1D) who elected to treat their diabetes with the Medtronic 670 G hybrid closed loop insulin pump.
- Trial name
- NCT04051632
- Testing
- Medtronic 670G insulin pump
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Boston Children's Hospital
Type 1 Diabetes
The Performance of an Artificial Pancreas at Home in People With Type 1 Diabetes
The overall aim of the study is to evaluate the performance of Artificial Pancreas or Closed Loop Glucose-Sensing Insulin-Delivery system in comparison to current best available technology represented by Sensor Augmented Pump…
- Trial name
- NCT02040571
- Testing
- Closed Loop, Open Loop
- Where
- Australia
- Volunteers
- 28 people
- Sponsor
- St Vincent's Hospital Melbourne
Type1diabetes
Impact of the Continuous Measurement of Blood Glucose on Insulin Pump on Child Quality of Life With Type 1 Diabetes
The implementation of a sensor of glycemia Enlite coupled with an insulin pump (Medtronic Minimed 640G) is a therapeutic option that Hospital of Mulhouse can propose to the children affected by type 1 diabetes.
- Trial name
- IM-CAPT (NCT03177096)
- Testing
- Peds QL questionnaire and diabetes modulate, WHO-5 questionnaire, Felt questionnaire
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Diabetes Mellitus, Type 1
Full Day and Night Closed-Loop With DiAs Platform
The overall aim of this proposed research is to determine the safety, feasibility and efficacy of the Diabetes Assistant (DiAs) controller in day and night closed-loop control in children and adolescents with type 1 diabetes over…
- Trial name
- NCT02147860
- Testing
- Diabetes Assistant (DiAs) with USS Virginia, Sensor Augmented Pump Therapy
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- University of Virginia
T1DM, Health Related Quality of Life
Health-related Quality of Life and Psychosocial Aspects of Diabetes Technology (Insulin Pumps)
This study will be prospective comparative trial comparing between insulin pumps vs Multiple daily injections (MDI) in treatment of type 1 diabetes mellitus (T1DM) in terms of health- related quality of life (HRQL) and efficacy…
- Conditions
- T1DM, Health Related Quality of Life, Insulin Pump
- Trial name
- NCT04756011
- Testing
- Health related quality of life
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Type 1 Diabetes
Effects of AHCL Insulin Pump on Glycemic Control and Psychosocial Outcomes in Pediatric Patients With Type 1 Diabetes
Prospective, non-randomized, single-arm clinical trial to investigate the effects of advanced hybrid close-loop (AHCL) system insulin pump in pediatric patients with type 1 diabetes
- Trial name
- NCT06414564
- Testing
- Medtronic 780G insulin pump
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Type 1 Diabetes Mellitus
Omnipod 5 Implementation in Belgian Paediatric Diabetes Care
This study will evaluate the introduction and use of the Omnipod® 5 hybrid closed-loop insulin delivery system in children and adolescents with type 1 diabetes following its reimbursement in Belgium.
- Trial name
- O5-IMPACT (NCT07785037)
- Testing
- Tubeless Hybrid Closed-Loop Insulin Delivery System
- Volunteers
- 200 people
- Sponsor
- Queen Fabiola Children's University Hospital
Type 1 Diabetes
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 15 Weeks in Adolescents and Adults With Type 1 Diabetes
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's…
- Trial name
- NCT02846857
- Testing
- 15-week intervention with sensor-augmented pump, 15-week intervention with single-hormone closed-loop, 15-week intervention with dual-hormone closed-loop
- Sponsor
- Institut de Recherches Cliniques de Montreal
Type 1 Diabetes
Tandem Control-IQ Evaluation Regarding Glucose Metrics, Sleep, and Health Economics
To evaluate Tandem Control-IQ compared with rtCGM and insulin pen respectively rtCGM and insulin pump treatment in children and adolescents regarding glucose control, sleep and health economics for 18 months.
- Trial name
- STARCARE (NCT05969106)
- Testing
- Tandem Control-IQ
- Where
- Sweden
- Volunteers
- 84 people
- Sponsor
- Vastra Gotaland Region
Type 1 Diabetes
Hypoglycemia at Initiation of Pump Therapy in Children With Type 1 Diabetes
The purpose of this study is to determine if patients have more hypoglycemic episodes the first 3 days following pump start compared to their usual number of hypoglycemias with our actual pump initiation protocol.
- Trial name
- NCT01840358
- Testing
- Observation of hypoglycemias frequency 3 days before and after pump initiation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- St. Justine's Hospital
Type 1 Diabetes
Closing the Loop in Adolescents During Non-compliance Behaviours
The ultimate goal of the investigators ongoing research is the development of a closed-loop system for insulin delivery, which can help people with type 1 diabetes (T1D) attain a tight glucose control avoiding the risk of…
- Trial name
- NCT01629277
- Testing
- Closed-loop, standard insulin pump
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Cambridge
Diabetes Mellitus, Type 1
Comparison With Observational Methods and Performance Assessment From Real-life Experience of Closed-Loop Insulin Delivery Systems
This study aims to compare glycemic control obtained under closed loop depending on the system : Smartguard (Medtronic 780) versus Control IQ (Tandem) in patients with diabetes type 1.
- Trial name
- COMPARE-CLIDS (NCT05932966)
- Testing
- Insulin closed-loop delivery system
- Where
- France
- Volunteers
- 317 people
- Sponsor
- Centre Hospitalier Sud Francilien
Type 1 Diabetes Mellitus
The Role of FTO Gene Polymorphism and Insulin Preparation in Obesity in Children With Type 1 Diabetes Mellitus
The project aims at assessment of the effect of the FTO gene polymorphism and the type of treatment on the development of overweight/obesity and features of metabolic syndrome in children with type 1 diabetes.
- Trial name
- FTO_T1DM (NCT01279161)
- Where
- 6 sites in Poland
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Bialystok
Diabetes Mellitus, Type 1
Evaluation of Minimed 670G in T1D Patients on Multiple Daily Injection
Introduction. Sensor Augmented Pump has demonstrated superiority over insulin pump and Multiple Daily Injection (MDI) in achieving optimal glucose control and can improve quality of life in Type 1 Diabetes (T1D) patients.
- Trial name
- NCT03755479
- Testing
- Hybrid Closed Loop Insulin Pump Minimed 670G
- Where
- Qatar
- Volunteers
- 30 people
- Sponsor
- Sidra Medicine