Clinical trials: Insulin Pump
Type 1 Diabetes Mellitus
Hyaluronidase Effect on Infusion Set Life
This research study examines the effect of hyaluronidase on the length of time of insulin infusion set wear. The aim of the study is to improve the length of time that an infusion set can be worn by infusing hyaluronidase…
- Trial name
- NCT02199028
- Testing
- Hyaluronidase, Control
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Type 1 Diabetes Mellitus
Safety and Efficacy of Initializing the Control-IQ Artificial Pancreas System Using Total Daily Insulin
The purpose of this proposed study is to assess the use of a new feature of the Control-IQ system, MyTDI.
- Trial name
- NCT03804983
- Testing
- Hybrid Closed Loop (HCL), Control-IQ with MyTDI
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Virginia
Type 1 Diabetes
The Effects of Regular Home Use Vs Diabetic Team- Supported Use of the Medtronic CareLink Therapy Management System.
Randomized, two arms, controlled, open study comprised of two consecutive segments. At the first segment that will last during the first 4 months of the study, patients will be randomized to the Care link treated group or non…
- Trial name
- CareLink (NCT00814476)
- Testing
- Medtronic CareLink therapy management system, regular home use and Medtronic CareLink Therapy Management
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- Rabin Medical Center
Type 1 Diabetes Mellitus
Insulin-based Strategies to Prevent Hypoglycemia During Exercise
It has been reported that insulin basal rate reduction initiated at exercise onset can reduce the hypoglycemic risk during exercise.
- Trial name
- NCT03349489
- Testing
- Exercise 1, Exercise 2, Dexcom G4 Platinum
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Type 1 Diabetes
Accu-Chek Combo in Young Patients
This is an open, prospective, descriptive study aiming to evaluate the change in treatment satisfaction of primary care givers of young children who use the Accu-Chek Combo System.
- Trial name
- NCT01657630
- Testing
- Accu-Chek Combo System
- Where
- Israel
- Volunteers
- 13 people
- Sponsor
- Rabin Medical Center
Type1diabetes
Assessment of Two Insulin Pump Insulin Delivery Systems in Type 1 Diabetes.
This is a study of the Minimed 670G 4.0 insulin pump, assessing the efficacy of the Advanced Hybrid Closed Loop (AHCL) algorithm in controlling blood glucose levels in Type 1 Diabetes.
- Trial name
- NCT04073576
- Testing
- AHCL, SAP+PLGM
- Where
- New Zealand
- Volunteers
- 60 people
- Sponsor
- Christchurch Clinical Studies Trust Ltd
Type 1 Diabetes
Fiasp® Versus NovoRapid® in Children With Type 1 Diabetes on MiniMed 640G Pump With Sensor
This is an exploratory, single-center retrospective cohort real-world study comparing safety and efficacy of Fiasp® versus NovoRapid® when used in the Medtronic MiniMed 640G system in pediatric subjects with Type 1 Diabetes…
- Trial name
- NCT04149262
- Testing
- Fast-acting insulin aspart, Rapid-acting insulin analogues (insulin aspart or insulin lispro)
- Where
- Greece
- Volunteers
- 44 people
- Sponsor
- Aristotle University Of Thessaloniki
Diabetes Mellitus, Type 1
Full Day and Night Closed-Loop With DiAs Platform
The overall aim of this proposed research is to determine the safety, feasibility and efficacy of the Diabetes Assistant (DiAs) controller in day and night closed-loop control in children and adolescents with type 1 diabetes over…
- Trial name
- NCT02147860
- Testing
- Diabetes Assistant (DiAs) with USS Virginia, Sensor Augmented Pump Therapy
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- University of Virginia
Diabetes Mellitus, Type 1 Diabetes
Supporting Medtronic 780G Insulin Pump Adoption in Latino Patients: A Spanish - Language Training Initiative
This study plans to learn more about whether a support program delivered in Spanish or both English and Spanish for bilingual families helps Latino youth with Type 1 Diabetes (T1D) successfully use the Medtronic MiniMed 780G…
- Trial name
- APOYO780G (NCT07720388)
- Testing
- Culturally and linguistically tailored onboarding and support program, Medtronic MiniMed 780G Insulin Pump System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Colorado, Denver
Type1 Diabetes Mellitus
Evaluation of the Dreamed Advisor Pro for Automated Insulin Pump Setting Adjustments in Children and Adolescents With Type 1 Diabetes- The Advice4U Pro Study
The DreaMed Advisor Pro is a software which automatically analyses treatment information, learns patient's needs and accordingly suggests adjustments in insulin dosing.
- Trial name
- Advice4U (NCT03003806)
- Testing
- DreaMed Advisor Pro, Medical guided recommendation
- Where
- 7 sites in United States, Germany and 2 more
- Volunteers
- 122 people
- Sponsor
- Rabin Medical Center
Type 1 Diabetes
Closed-loop Control of Postprandial Glucose Levels in Children and Adults With Type 1 Diabetes
Current intensive insulin therapy in T1D involves prandial insulin boluses depending on the carbohydrate content of each ingested meal.
- Trial name
- NCT02490098
- Testing
- 6-day intervention with sensor-augmented pump therapy, 6-day intervention with single-hormone closed-loop strategy, 6-day intervention with dual-hormone closed-loop strategy
- Where
- Canada
- Sponsor
- Institut de Recherches Cliniques de Montreal
Diabetes
Post Approval Study of the TS Feature With the 530G Pump System Supplemented With Commercial Patient Data
The purpose of this study is to evaluate the Threshold Suspend (TS) feature of the Medtronic MiniMed® 530G insulin pump in patients 16 and older with insulin requiring diabetes.
- Trial name
- NCT02003898
- Testing
- Medtronic MiniMed 530G Insulin Pump
- Where
- 43 sites in United States
- Volunteers
- 372 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 1 Diabetes
Closing the Loop in Adolescents During Non-compliance Behaviours
The ultimate goal of the investigators ongoing research is the development of a closed-loop system for insulin delivery, which can help people with type 1 diabetes (T1D) attain a tight glucose control avoiding the risk of…
- Trial name
- NCT01629277
- Testing
- Closed-loop, standard insulin pump
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Cambridge
Diabetes Mellitus, Type 1
Automated Insulin Delivery for Type 1 Diabetes - Beyond Glucose Metrics
The goal of this clinical trial is to determine if transitioning to automated insulin delivery (AID) systems, can improve objectively measured sleep quality and quantity and alleviate cardiovascular risk factors in both children…
- Trial name
- AID-BEYOND (NCT06469593)
- Testing
- Automated insuling delivery system
- Where
- 3 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- Steno Diabetes Center Copenhagen
Diabetes Mellitus, Type 1
Insulin Lispro 6 Days Versus Insulin Aspart 6 Days in Pump Use
Patients will continue to use their current insulin pump for this study. Patients will receive insulin lispro and insulin aspart during this study.
- Trial name
- NCT01134107
- Testing
- Insulin Lispro 6 Day (6D), Insulin Aspart 6 Day (6D)
- Where
- 15 sites in France, Germany and 1 more
- Volunteers
- 133 people
- Sponsor
- Eli Lilly and Company
Type 1 Diabetes
Qingdao: Insulin Pump Follow-Up Program
The purpose of the study is to observe/ collect clinical data, subject users' feedback, and device data to better understand the real-life usage and acceptance of the 722 Pump in type 1 diabetes subjects,<18 years of age, and the…
- Trial name
- NCT02655666
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Medtronic MiniMed, Inc.
Diabetes Mellitus, Diabetes Mellitus, Type 1
Home Testing of Day and Night Closed Loop With Pump Suspend Feature
The main study objective is to determine whether day and night automated closed loop glucose control combined with pump suspend feature will improve glucose control and reduce the burden of hypoglycaemia compared to sensor…
- Conditions
- Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders, Endocrine System Diseases
- Trial name
- APCam11 (NCT02523131)
- Testing
- FlorenceM, Medtronic insulin pump 640G
- Where
- 8 sites in United States, United Kingdom
- Volunteers
- 84 people
- Sponsor
- University of Cambridge
Type 1 Diabetes
Closed-loop Control of Glucose Levels (Artificial Pancreas) for 24 Hours in Adults and Adolescents With Type 1 Diabetes
Closed-loop strategy is composed of three components: glucose sensor to read glucose levels, insulin pump to infuse insulin and a dosing mathematical algorithm to decide on the required insulin dosages based on the sensor's…
- Trial name
- NCT01754337
- Testing
- Closed-loop system
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Patient Care, Drug Therapy
Comparison of Two Management Systems in Patients With Type 1 Diabetes (Pediatric SmartHome)
Closed loop technology has been shown to reduce both hypoglycemia and hyperglycemia, as well as reduce glycemic variability. Sensor augmented pump (SAP) therapy means the addition of alerts according to high or low glucose values…
- Trial name
- NCT03815487
- Testing
- Medtronic MiniMed 670G Insulin Pump in Auto Mode, Medtronic MiniMed 670G Insulin Pump without Auto Mode
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Kinderkrankenhaus auf der Bult
Type 1 Diabetes, Type 2 Diabetes
User Evaluation of the MiniMed 620G and 640G Insulin Pumps
This six center international study will include two United Kingdom National Health Service centers, two centers in Melbourne, Australia and one center each in Denmark and Spain.
- Trial name
- NCT01726621
- Testing
- Medtronic MiniMed 620G or 640G Insulin Pump
- Where
- 6 sites in Australia, Denmark and 2 more
- Volunteers
- 55 people
- Sponsor
- Medtronic MiniMed, Inc.