Clinical trials: Integrated Care
Inappropriate Prescribing, Primary Health Care
Deprescribing in Primary Health Care
Medications can help older adults but can also harm them. Frail older adults tend to have many health problems that require treatment, but are also at risk of harm from the medications prescribed.
- Conditions
- Inappropriate Prescribing, Primary Health Care, Polypharmacy
- Trial name
- NCT03903484
- Testing
- Deprescribing toolbox and intervention
- Where
- Canada
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Hypertensive Disorder of Pregnancy
Thriving Hearts: Healing-Centered, Integrated, Community Maternity Care
The overarching goal of Thriving Hearts is to implement a multi-level program through Local Health Departments (LHDs) that cultivates conditions for mothers and birthing people to not only survive pregnancy, but to thrive.
- Trial name
- NCT06744231
- Testing
- Usual Care, Thriving Hearts
- Where
- United States
- Volunteers
- 17,500 people
- Sponsor
- University of North Carolina, Chapel Hill
Implementation Research, Depressive Disorder
Pediatric Behavioral Health Integrated Care: Indiana Statewide Strategic Plan to Address the Growing Mental Health Crisis
This research is designed to analyze the implementation and fidelity of Pediatric Integrated Behavioral Health (PEDS-IBH). PEDS-IBH is a multifaceted project designed to address the pediatric mental health crisis by providing…
- Conditions
- Implementation Research, Depressive Disorder, ANXIETY DISORDERS (or Anxiety and Phobic Neuroses), Conduct Disorders in Children
- Trial name
- PEDS-IBH (NCT07216638)
- Where
- United States
- Volunteers
- 575 people
- Sponsor
- Indiana University
Neisseria Gonorrhea, Trichomoniasis Vaginalis
Acceptability Research on Integrated Point of Care Sexually Transmitted Infection (STI) Testing and Expedited Partner Therapy (EPT)
This protocol builds on nearly a decade of collaborative HIV/STI prevention research to conduct a prospective cohort study of Adolescent Girls and Young Women (AGYW) eligible for PrEP in South Africa in which we will assess the…
- Conditions
- Neisseria Gonorrhea, Trichomoniasis Vaginalis, Chlamydia Trachomatis Infection
- Trial name
- ARISE (NCT06570733)
- Where
- South Africa
- Volunteers
- 305 people
- Sponsor
- Wits RHI Research Centre Clinical Research Site
Integrated Care, Adolescent
Integrated HPV Vaccination and Adolescent Health in Tanzania
Background: Cervical cancer is a serious global public health problem, particularly in sub-Saharan Africa, where it is the leading cause of cancer in women, with around 70,722 new cases each year.
- Conditions
- Integrated Care, Adolescent, HPV
- Trial name
- SHARP-TZ (NCT06915844)
- Testing
- SHARP Tanzania
- Where
- Tanzania
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Jhpiego
Stroke
Carepartner Collaborative Integrated Therapy Gait (CARE-CITE-Gait) Program
Stroke affects both the carepartner (CP) and stroke survivor (SS), with CPs frequently feeling overwhelmed and exhausted. The investigators have developed a theory-based, family-centered intervention, Carepartner Collaborative…
- Trial name
- NCT05257928
- Testing
- CARE-CITE Gait
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Emory University
Health Behavior, Health Lifestyle Behaviors
Laughter Yoga Integrated PRECEDE-PROCEED Health Education Program in Adolescents
Adolescence is a critical developmental period in which lifelong health behaviors are shaped, and behaviors acquired during this stage significantly influence health outcomes in adulthood.
- Conditions
- Health Behavior, Health Lifestyle Behaviors, Adolescent, Adolescent Behavior
- Trial name
- Lifestyle (NCT07607847)
- Testing
- Laughter yoga-integrated health education
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Ankara University
Premature Birth
Family Integrated Care (FICare) in Level II NICUs
In Alberta, nearly one in every twelve babies is born too soon (preterm). Preterm babies are at greater risk for breathing and feeding problems, as well as infections, than babies born on their due date (full term).
- Trial name
- FICare (NCT02879799)
- Testing
- Implement Family Integrated Care
- Where
- 10 sites in Canada
- Volunteers
- 765 people
- Sponsor
- University of Calgary
Major Depressive Disorder
Effectiveness of an Integrated Care Pathway for Depression: Cluster Randomized Controlled Trial
This is a quasi-experimental, multi-site cluster controlled clinical trial design with two intervention arms--Treatment As Usual (TAU) and an Integrated Care Pathway (ICP).
- Trial name
- CARIBOU-2 (NCT05142683)
- Testing
- Treatment As Usual, CARIBOU-2
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Distress; Maternal, Self Efficacy
Integrated Intervention for Caregivers--Pilot RCT
Adolescents who have been hospitalized for suicidal behavior are at risk for engaging in additional suicidal behavior. After hospitalization, parents or guardians are typically asked to be responsible for helping to prevent…
- Conditions
- Distress; Maternal, Self Efficacy, Parenting, Suicide
- Trial name
- NCT03487627
- Testing
- Electronic and Care Support Manager Contact, Enhanced Treatment-as-usual (TAU)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Wake Forest University Health Sciences
Malnutrition, Child, Nutrition Poor
Implementation of P-INPAC
The framework for Pediatric Integrated Nutrition Pathway for Acute Care (P-INPAC) was developed by the Canadian Malnutrition Task Force (CMTF); however, it has not been implemented in a research setting.
- Trial name
- P-INPAC (NCT06645639)
- Testing
- Pediatric Integrated Nutrition Pathway for Acute Care Pathway (P-INPAC)
- Where
- 3 sites in Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Depression, Anxiety, Antenatal Depression
Integration of Stepped Care for Perinatal Mood and Anxiety Disorders Among Women Attending MCH Clinics
Perinatal mood and anxiety disorders (PMAD), defined as depression and anxiety during pregnancy or up to 1 year postpartum, account for substantial morbidity and mortality among birthing people globally especially in low- and…
- Conditions
- Depression, Anxiety, Antenatal Depression, Postnatal Depression
- Trial name
- IPMH (NCT06456307)
- Testing
- Integrated Perinatal Mental health program (systematic screening for PMAD, PM+ and tele-psychiatry)
- Where
- 2 sites in Kenya
- Volunteers
- 2,970 people, healthy volunteers welcome
- Sponsor
- Kenyatta National Hospital
Opioid Use Disorder, HIV
Expanded HIV Care in Opioid Substitution Treatment (EHOST) Trial
Opioid Substitution Treatment (OST) provides a critical opportunity for HIV testing and linkage to antiretroviral treatment. The EHOST study will evaluate a prescriber-focused intervention to increase HIV testing rates, and…
- Trial name
- EHOST (NCT02440256)
- Testing
- Expanded HIV care in Opioid Substitution Treatment
- Volunteers
- 49 people
- Sponsor
- Simon Fraser University
Childhood Severe Illness, Pneumonia
Tools for the Integrated Management of Childhood Illness: Cross-country Quasi-experimental Pre-post Study in Kenya and Senegal
By introducing pulse oximetry, with or without clinical decision support algorithms, to primary care facilities in India, Kenya, Senegal and Tanzania, the Tools for Integrated Management of Childhood Illness (TIMCI) project aims…
- Conditions
- Childhood Severe Illness, Pneumonia, Primary Health Care, Hypoxia
- Trial name
- TIMCI (NCT05065320)
- Where
- 2 sites in Kenya, Senegal
- Volunteers
- 51,590 people, healthy volunteers welcome
- Sponsor
- Swiss Tropical & Public Health Institute
Mental Health Wellness 1, Premature Birth
Fathers and Partners in Family Integrated Care Study
AIMS: The primary aim is to investigate the impact of enhancing father/partner engagement in FICare of preterm infants on their mental health (MH) up to 6 weeks post discharge.
- Trial name
- TARGET (NCT06022991)
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Homerton University Hospital NHS Foundation Trust
Malnutrition, Intestinal Diseases, Parasitic
The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas
Worldwide, over 2 billion people suffer from worm infections in developing countries. These infections are especially damaging to the health of children, resulting in both short-term and lifelong disability.
- Trial name
- NCT01314937
- Testing
- Mebendazole, Usual care
- Where
- Peru
- Volunteers
- 1,760 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Respiratory Insufficiency
Integrated Pulmonary Index (IPI) as a Determinate of Weaning Success and/or Failure in the Pediatric Population
Integrated pulmonary index (IPI) is a tool that monitors respiratory status. It takes into account four parameters: respiratory rate, end-tidal CO2, heart rate and O2 saturation using a pulse oximeter and specialized sidestream…
- Trial name
- IPI (NCT01795196)
- Where
- United States
- Sponsor
- Rush University Medical Center
Type 1 Diabetes (T1D)
Adapting Single Sessions Interventions for Type 1 Diabetes
The goal of this clinical trial is to learn if implementing a single-session depression intervention for youth with type 1 diabetes (T1D) is feasible and acceptable to patients. can help improve mood and health outcomes.
- Trial name
- ASSISTED (NCT06752369)
- Testing
- T1D-specific depression SSI, T1D Educational
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Nemours Children's Health System
Integrated Care, HPV Vaccination
Integrated HPV Vaccination and Adolescent Health in Ivory Coast
Background: Cervical cancer is a serious global public health problem, particularly in sub-Saharan Africa, where it is the leading cause of cancer in women, with around 70,722 new cases each year.
- Conditions
- Integrated Care, HPV Vaccination, Adolescent
- Trial name
- SHARP-CI (NCT06997705)
- Testing
- Optimized VMS
- Where
- Côte d’Ivoire
- Volunteers
- 3,384 people, healthy volunteers welcome
- Sponsor
- Jhpiego
HIV
Integrated Care Delivery of HIV Prevention and Treatment in AGYW in Zambia
The study team will test a multilevel package of interventions to connect adolescent girls and young women (AGYW) with a source of regular care to provide a sustainable platform for successful implementation of regular human…
- Trial name
- NCT03995953
- Testing
- SHIELD intervention (Support for HIV Integrated Education, Linkages to care, and Destigmatization), Integrated wellness care (IWC) clinics
- Where
- Zambia
- Volunteers
- 2,150 people
- Sponsor
- RTI International