Clinical trials: Intensive Care Patients
Pressure Injury, Risk Assessment
Positioning Duration and Pressure Injury Risk
This research aims to investigate the effect of positioning times on the risk of pressure injury in critically ill patients.
- Trial name
- PIP-ICU (NCT07355439)
- Testing
- Position Change - 1 Hour, Position Change - 2 Hours
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- SEMA ŞAHİNER
Intestinal Failure
AI-driven Total Parenteral Nutrition Platform
This study tests whether an artificial intelligence (AI) tool can help doctors order total parenteral nutrition (TPN) for babies in the neonatal intensive care unit (NICU).
- Trial name
- NCT07414576
- Testing
- AI-driven total parenteral nutrition (TPN)
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Takeoff41, Inc.
Neonatal Intensive Care Unit, Medication Errors
Drug-Related Problems in Neonatal Patients
Drug-related problems in newborn babies have been reported with a rate of 4-30%. It is estimated that the higher rates of these problems in hospitalized children under the age of two are related to the variety of drugs used and…
- Conditions
- Neonatal Intensive Care Unit, Medication Errors, Drug-Related Problems, Adverse Drug Event
- Trial name
- NCT04899960
- Testing
- Clinical Pharmacist Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 512 people
- Sponsor
- Hacettepe University
Respiratory Disease
The Efficiency of Chest Physiotherapy Applied in a Different Order
This study intends to compare the impact of chest physiotherapy applied with two different methods on physiologic parameters in children hospitalized in the intensive care unit.
- Trial name
- NCT05022082
- Testing
- Chest Physiotherapy- Aspiration- Inhaler drugs group
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Selmin Kose
Critical Illness, Burnout, Professional
Effect of Around the Clock Intensivist Coverage on Intensive Care Unit (ICU) Outcomes
Intensive Care Units (ICU) are an important, but troubled, part of modern health care systems. While it seems likely that both the technical and structural elements of ICU care are important determinants of relevant ICU outcomes…
- Conditions
- Critical Illness, Burnout, Professional, Education, Medical, Patient Satisfaction
- Trial name
- NCT01146691
- Testing
- Alternative Intensivist staffing models
- Where
- 2 sites in Canada
- Volunteers
- 627 people
- Sponsor
- University of Manitoba
Burn Injury, Burns
Foreign-National Burn Patients in a Border-Region Burn Center
This retrospective cohort study will evaluate burn patients hospitalized and treated at the Burn Center of Gaziantep City Hospital between October 2023 and June 2026.
- Trial name
- NCT07673796
- Volunteers
- 1,400 people
- Sponsor
- Gaziantep City Hospital
Severe Infection, Severe Immune Deficiency
Systematic Screening for Primary Immunodeficiencies in Patients Admitted for Severe Infection in Pediatric Intensive Care Unit
Severe infections in pediatric intensive care unit are not uncommon. Historically, the diagnosis of hereditary (primary) immune deficiency required a combination of recurrent clinical signs and biological stigmas.
- Trial name
- SPYSI (NCT04990908)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Chronic Disease
Intensive Management of At-risk Patients
The purpose of this study is to assess if intensive management of at-risk participants, utilizing longitudinal patient tracking, proactive outreach, multidisciplinary action planning and careful outcomes monitoring, will lead to…
- Trial name
- NCT04456725
- Testing
- Intensive management, Control
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- CareMore Health, San Bernardino
Eye Care, Nursing Care
Effects of Two Different Eye Care Practices on Eye Complications in Mechanically Ventilated Intensive Care Patients
This study was designed as a prospective, randomized controlled experimental study aiming to compare different approaches to eye care in intensive care patients receiving mechanical ventilation.
- Conditions
- Eye Care, Nursing Care, Intensive Care Unit
- Trial name
- NCT07070843
- Testing
- Control Group: Standard Eye Care Group, Intervention Group 1: Eye Care Using an Eye Care Kit, Intervention Group 2: Eye Care According to an Eye Care Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Istanbul Saglik Bilimleri University
Analgesia
Lorazepam for the Analgosedation of Pediatric Patients in Mechanical Ventilation.
The aim of this study is to better define the pharmacokinetic and pharmacodynamic profile of lorazepam for the analgosedation in pediatric intensive care unit.
- Trial name
- NCT04646135
- Testing
- Lorazepam 4 mg/ml
- Volunteers
- 9 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Mechanical Ventilation Complication
Assessing Gas Exchange in Intensive Care Patients on a Ventilator
In an attempt to standardise the degree of impairment of gas exchange in the lungs of ICU patients a number of indices of oxygen exchange have been developed.
- Trial name
- NCT02599350
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Aberdeen
Covid19, Critically Ill
Risk Factors for Mortality for COVID-19 Admitted to an Intensive Care Unit
Studying clinical characterization of critically ill COVID-19 patients in a single center Studying Risk factors for Day 28 Mortality in COVID-19 patients admitted to intensive care unit
- Trial name
- ICUCOVID-KK (NCT04805645)
- Testing
- No intervention (Retrospective Cohort Observational)
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Clinical Research Centre, Malaysia
Preterm Birth, Prematurity
Parent-child Interactions, Child Developmental Health, and Health System Costs at 6 Months Corrected Age
The aim of this novel health services research proposal is to assess the longer-term outcomes, to 6 months corrected age, of an adapted Family Integrated Care (FICare) model of care for moderate and late preterm infants admitted…
- Conditions
- Preterm Birth, Prematurity, Infant,Premature, Infant Development
- Trial name
- NCT03357458
- Testing
- Family Integrated Care
- Where
- Canada
- Volunteers
- 56 people
- Sponsor
- University of Calgary
Delirium
The Delirium-CS Canada Study
Delirium is a prevalent complication following cardiac surgery that is under-recognized using current methods of delirium detection and that may be better identified through a systematic and standardized perioperative screening…
- Trial name
- DELIRIUM-CS (NCT02206880)
- Where
- 12 sites in Canada
- Volunteers
- 235 people
- Sponsor
- St. Boniface Hospital
Arterial Hypotension in Critically Ill Neonatal and Pediatric Patients
Copeptin and Arterial Hypotension in Critically Ill Paediatric and Neonatal Intensive Care Patients
Blood copeptin will be measured during the routine treatment of neonates, children and adolescents on the Intensive Care Unit of the University Children's Hospital Zurich at different time points (admission, 12, 24, 48, 96, 168…
- Trial name
- COPNIC (NCT03320967)
- Testing
- Copeptin in plasma
- Where
- Switzerland
- Volunteers
- 170 people
- Sponsor
- Vincenzo Cannizzaro
Sedation in Intensive Care
Efficacy, Safety and Pharmacokinetic Study of Intravenous Clonidine Versus Midazolam for Sedation in Paediatric Patients
Closed1 aims to compare the efficacy, safety and pharmacokinetics of clonidine (hydrochloride) to midazolam in the sedation of ventilated children and adolescents (0-18 years) admitted to a paediatric intensive care unit (PICU)…
- Trial name
- CloSed1 (NCT02509273)
- Testing
- Clonidine, Midazolam
- Where
- 10 sites in Czechia, Estonia and 5 more
- Volunteers
- 28 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
AKI
Preadmission Metformin Exposure and Incidence of Acute Kidney Injury
More than 50% of ICU patients suffer from Acute kidney injury (AKI). Metformin shows protective properties in kidney disease. Our study aimed to validate AKI incidence among diabetes patients in the ICU with or without…
- Trial name
- NCT04631289
- Where
- China
- Volunteers
- 3,841 people
- Sponsor
- Second Affiliated Hospital of Guangzhou Medical University
Liver Transplantation, Infection
Italian National Study on the Critically Ill Liver Transplant Patient With an Infection
Despite major advances, infections remain one of the major causes of morbidity and mortality in patients undergoing orthotopic liver transplantation (OLT).
- Conditions
- Liver Transplantation, Infection, Sepsis, Intensive Care Unit
- Trial name
- INFE-OLT (NCT03363646)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Airway Clearance, Mechanical Insufflation-exsufflation
Mechanical Insufflation-Exsufflation in Critically Ill Patients
Mechanical insufflation-exsufflation (MI-E) is an established airway clearance technique for patients with chronic conditions like neuromuscular diseases.
- Conditions
- Airway Clearance, Mechanical Insufflation-exsufflation, Mechanical Insufflation-exsufflation Session ( With Cough Assist), Delphi Study
- Trial name
- DELMI-E (NCT07420946)
- Testing
- Delphi Questionnaire
- Where
- 4 sites in Italy, Spain and 1 more
- Volunteers
- 30 people
- Sponsor
- Medipol University
Traumatic Brain Injury
Development and Validation of a Prognostic Score for Early Death in Head Injury Patients.
Traumatic brain injury (TBI) is a serious condition with high morbidity and mortality. The Glasgow score alone, assessed at the initial phase, is not enough to determine the prognosis.
- Trial name
- SCORE TC (NCT02861547)
- Testing
- death
- Where
- France
- Volunteers
- 355 people
- Sponsor
- Centre Hospitalier Universitaire Dijon