Clinical trials: Intensive Care Unit Patients
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
Critical Illness
Administrative Workload in the Intensive Care Unit
A prospective observational study in the Intensive Care Unit and the Medium Care Unit in a university hospital in Amsterdam. Recent studies show that administrative tasks occupy more than 30% of the workload.
- Trial name
- AWIC (NCT02730221)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Amsterdam UMC, location VUmc
Fluid Overload Pulmonary Edema, Fluid Overload
Lung Ultrasound-guided Fluid Therapy in Pediatric Intensive Care Unit Patients
A randomized clinical trial to evaluate the effect of using pulmonary ultrasound to guide fluid therapy on distinct variables.
- Conditions
- Fluid Overload Pulmonary Edema, Fluid Overload, Pneumonia, Ventilator-Associated, Fluid Overload Without Edema
- Trial name
- NCT04215692
- Testing
- Pulmonary ultrasound
- Where
- Mexico
- Volunteers
- 68 people
- Sponsor
- Instituto Mexicano del Seguro Social
Mechanical Ventilation, Pulmonary Rehabilitation
Rehabilitation Practices in Critically Ill Patients Receiving Invasive Mechanical Ventilation in the Intensive Care Unit.
This international, multicenter, observational study aims to describe rehabilitation practices in Intensive Care Units (ICUs) worldwide.
- Conditions
- Mechanical Ventilation, Pulmonary Rehabilitation, Intensive Care Units (ICUs), Quality of Life (QOL)
- Trial name
- REPOrt (NCT07093125)
- Where
- Italy
- Volunteers
- 2,400 people
- Sponsor
- Universita degli Studi di Genova
Intensive Care Unit Syndrome
System for Postoperative Admission to ICU for Patients With Digestive System Malignancy
Postoperative admission to ICU for patients with digestive system tumors is one of the most common postoperative complications of all non-cardiac surgeries.
- Trial name
- NCT06277518
- Testing
- Surgery for malignant tumors of the digestive system
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- General Hospital of Ningxia Medical University
Critical Illness, Postoperative Complications
General Surgery Patients at the Intensive Care Unit
Introduction: high-risk surgical patients in the intensive care unit (ICU) are a unique population that has yet to be carefully monitored.
- Trial name
- TraViII (NCT06731296)
- Testing
- Presence of a risk factor
- Where
- 2 sites in Colombia
- Volunteers
- 1,000 people
- Sponsor
- Hospital Departamental de Villavicencio
Respiratory Failure, Treatment Outcome
Pattern of Admission and Outcome of Patients Admitted to the Intensive Care
The study was a retrospective observational cohort where patient medical record review was done and data were gathered on 419 cases.
- Trial name
- ICU (NCT05591209)
- Where
- 2 sites in Ethiopia
- Volunteers
- 419 people
- Sponsor
- Haramaya Unversity
Septic Shock
Right Ventricular Dysfunction in Septic Shock Patients in ICU
Assesment of right ventricular dysfunction in septic shock patients in intensive care unit.
- Trial name
- Septicshock (NCT05193682)
- Volunteers
- 25 people
- Sponsor
- Shimaa Hammad Ahmed
Videolaryngoscopy, Intensive Care Unit Syndrome
Awake Tracheal Intubation in Critical Care Patients
Tracheal intubation in critical care is a high-risk procedure requiring significant expertise and airway strategy modifications, such as awake intubation with video laryngoscope or flexible endoscope intubation.
- Trial name
- Awake (NCT05802316)
- Testing
- tracheal intubation using videolaryngoscope with a hyperangulated blade or standard intubation videolaryngoscopy (VL) and direct laryngoscopy (DL)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Johannes Gutenberg University Mainz
Critical Illness
European Mortality & Length Of Intensive Care Unit (ICU) Stay Evaluation (ELOISE)
The starting point of ELOISE is the significant number of Intensive Care Unit (ICU) survivors who die after the transfer to ward.
- Trial name
- ELOISE (NCT01422070)
- Where
- Italy
- Volunteers
- 6,433 people
- Sponsor
- Università degli Studi di Ferrara
Acute Respiratory Distress Syndrome, Pneumonia in Children
Using Artificial Intelligence To Improve Ventilator Settings For Intensive Care Patients
This observational study aims to determine whether an AI-assisted decision support system can improve clinical outcomes for mechanically ventilated pediatric patients (aged 1 month to 18 years) in the PICU, compared to standard…
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients)
- Trial name
- NCT07592039
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Wu Rongzhou
Delirium
The ICU DElirium in Clinical PracTice Implementation Evaluation Study Screening and Treatment
Objective: Delirium is an important and frequently occurring complication in intensive care patients. However, screening and treatment of delirium is not in accordance with current national and international guidelines.
- Trial name
- iDECePTIvE (NCT01952899)
- Where
- Netherlands
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Adult Patients Managed in a Cardiac Critical Care Unit With a Pathology Requiring at Least One Potentially Painful and Anxiety-provoking Invasive Procedure
Reorganization Strategy to Optimize the Use of Virtual Reality
The benefits of virtual reality (VR) in managing pain and anxiety for critical care patients has never been demonstrated, even if a positive effect has been demonstrated in other populations of patients.
- Trial name
- S'OUVRIR (NCT07132710)
- Testing
- Semi-structured interviews
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Sleep, Intensive Care Unit Syndrome
Sleep Bundle for Improving Sleep in ICU Patients
Summary of the project : Lack or disturbances of sleep are major problems in patients staying in intensive care unit (ICU) due to the particular environment.
- Trial name
- NCT03247062
- Testing
- Quality improvement - sleep bundle
- Volunteers
- 130 people
- Sponsor
- University Hospital, Geneva
Respiration, Artificial
Patient-ventilator Asynchrony During Mechanical Invasive Assisted-ventilation in Pediatric Patients
The purpose of this study is to document the prevalence and type of asynchronies incidence during invasive mechanical ventilation in pediatric patients breathing under pressure support.
- Trial name
- NavPed-Inv (NCT01193023)
- Testing
- Pressure Support, NAVA
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Geneva
Oral Bacterial Colonization, Oral Hygiene
Effects of Three Oral Hygiene Protocols on Oral Bacteria in Intensive Care Patients
Patients in intensive care may develop changes in the bacteria found in their mouths. Some of these bacteria can cause infections, and patients who cannot clean their own teeth depend on staff to provide oral care.
- Trial name
- NCT07868549
- Testing
- Mechanical Oral Hygiene, Chlorhexidine, Hexetidine
- Where
- Croatia
- Volunteers
- 86 people
- Sponsor
- University of Zagreb
Bacterial Infections
Compliance With AntibIotic TherapY Guidelines in French PICUs
This observational, prospective, multicenter study, conducted in nine French Pediatric and Neonatal Intensive Care Units (ICUs), will assess the antibiotic therapy for a child hospitalized in ICU and receiving systemic…
- Trial name
- COMITY (NCT04642560)
- Where
- France
- Volunteers
- 134 people
- Sponsor
- University Hospital, Toulouse
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health
Critical Illness, Respiratory Failure
Sedation in the Intensive Care Unit
High-risk critically ill patients often require mechanical ventilation either to primarily support the respiratory function or when the ventilation is insufficient to maintain adequate gas exchanges as a result of other organ…
- Trial name
- NCT00221520
- Testing
- midazolam with 2 different levels of sedation scores
- Where
- Switzerland
- Volunteers
- 126 people
- Sponsor
- University Hospital, Geneva
Terminally Ill Patients
Mobile Shared Decision-Making Program for ICU Caregivers
By developing a smart mobile shared decision-making (SDM) model, this study aims to assist family members of critically ill end-stage patients in making appropriate decisions, enhance their decision quality, and evaluate the…
- Trial name
- NCT07469878
- Testing
- Experimental: Mobile technology devices
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- CHIA-HUI MA