Clinical trials: Intensive Care Units
Critical Illness, Post Intensive Care Unit Syndrome
Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study
Pediatric Intensive Care Unit (PICU) survival has increased substantially over the past three decades. Currently, an understanding of PICU morbidity and recovery among PICU survivors and their families is limited.
- Trial name
- PICS-p (NCT04967365)
- Where
- 30 sites in United States
- Volunteers
- 755 people
- Sponsor
- University of Pennsylvania
Nutrition Disorders, Gastrointestinal Disease
Review of Infant Oral Feeding and Skills
This study evaluates the infant's feeding skill level at discharge from the neonatal intensive care unit. The goal is to determine whether the ability to "full feed by volume" implies "full skill development" for infant oral…
- Conditions
- Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties
- Trial name
- RIOS (NCT06736743)
- Testing
- SMART Tool for Feeding Skill Assessment
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Wake Forest University Health Sciences
Preterm Infant, Infant, Premature
Pilot Study of the SENSITIVE Care Program for Preterm Infants in the Neonatal Intensive Care Unit
The goal of this clinical trial is to learn whether the Sensory Integrative Intervention (SENSITIVE) Care Program helps reduce stress and improve mother-infant interaction in preterm infants receiving care in the Neonatal…
- Conditions
- Preterm Infant, Infant, Premature, Neonatal Intensive Care Unit (NICU)
- Trial name
- SENSITIVE Care (NCT07728760)
- Testing
- SENSITIVE Care Program, Standard Neonatal Intensive Care
- Where
- Indonesia
- Volunteers
- 8 people
- Sponsor
- Gadjah Mada University
Acute Kidney Injury, Renal Replacement Therapy
FST Analysis Supporting Timely Therapy and Risk Assessment Via Clinical Decision Support for Kids
The goal of this study is to learn whether adding a clinical decision support tool to the electronic medical record helps clinicians use the furosemide stress test in critically ill children at high risk for severe acute kidney…
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Unit
- Trial name
- FAST TRACK (NCT07718464)
- Testing
- Furosemide Stress Test Clinical Decision Support Tool
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Neonatal Intensive Care Unit
Reducing Fluids Intakes in Neonatal Intensive Care
During stay in the neonatal intensive care unit, newborns requires various treatments administered intravenously. The hidden fluid intake associated with these infusion can lead to fluid overlad, increasing the risk of…
- Trial name
- REFINI (NCT07715513)
- Testing
- hidden fluid intake
- Where
- France
- Volunteers
- 9 people
- Sponsor
- University Hospital, Clermont-Ferrand
Study of Predictors of Successful Extubation in Preterm Infants, Extubation Succeeded
Neonatal Diaphragmatic Activity-Linked Extubation Conditions and Timing
The objective of this study is to evaluate the role of diaphragmatic electrical activity monitoring (collected by esophageal probe) around extubation of preterm patients in order to consider its use as a standardized objective…
- Conditions
- Study of Predictors of Successful Extubation in Preterm Infants, Extubation Succeeded, Extubation Failure, Preterm
- Trial name
- NEODIALECT (NCT07709988)
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Catheter-Related Infections, Central Venous Catheters
Advanced Dressings for CVC Infection Prevention in PICU
Randomised, single-blind clinical trial comparing chlorhexidine gluconate-impregnated transparent dressings versus conventional transparent dressings in the prevention of central venous catheter-related bloodstream infections…
- Conditions
- Catheter-Related Infections, Central Venous Catheters, Bloodstream Infection, Pediatric Intensive Care Units
- Trial name
- NCT07175116
- Testing
- 3M™ Tegaderm™ Antimicrobial Transparent Dressing (chlorhexidine gluconate-impregnated), Conventional transparent polyurethane dressing
- Where
- Spain
- Volunteers
- 250 people
- Sponsor
- University of Seville
Infant, Extremely Premature, Obstetric Labor, Premature
Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset
The goal of the Tiny Baby Collaborative Multicenter Inventory of Neonatal-Perinatal Interventions (MINI) minimum dataset is to serve as a registry detailing the outcomes and practices for all deliveries and infants admitted to…
- Conditions
- Infant, Extremely Premature, Obstetric Labor, Premature, Premature Birth, Intensive Care, Neonatal
- Trial name
- NCT05685745
- Where
- 59 sites in United States, Australia and 6 more
- Volunteers
- 5,000 people
- Sponsor
- The University of Texas Health Science Center, Houston
Respiratory Distress Syndrome, Newborn, Pulmonary Surfactants
Echography-guided Surfactant THERapy (ESTHER) For Preterm Infants With Respiratory Failure
Point-of-care ultrasound (POCUS) is the use of ultrasound by the bedside provider in real time to answer a specific question and guide medical management.
- Conditions
- Respiratory Distress Syndrome, Newborn, Pulmonary Surfactants, Intensive Care Units, Neonatal
- Trial name
- NCT06446453
- Testing
- Echography-guided Surfactant THERapy (ESTHER)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Connecticut Children's Medical Center
Neonatal Pain, Retinopathy of Prematurity (ROP)
Fentanyl Intranasal for Retinopathy of Prematurity Screening in Preterm Infants
The goal of this clinical trial is to learn whether intranasal fentanyl (a pain medicine given as a nasal spray) can reduce pain and is safe to use during routine eye examinations for retinopathy of prematurity (ROP) in preterm…
- Conditions
- Neonatal Pain, Retinopathy of Prematurity (ROP), Pain Management, Infant, Premature
- Trial name
- FIREFLY (NCT07112430)
- Testing
- Fentanyl Citrate (Intranasal)
- Where
- Canada
- Volunteers
- 58 people
- Sponsor
- Marsha Campbell-Yeo
Intensive Care Unit Syndrome
PREMAPIV : Intravesical Pressure Variation at Different Bladder Instillation Volumes in Newborn Children
Abdominal Compartment Syndrome (ASC) is defined by an Intra Abdominal Hypertension (IAH) associated with a new organ failure. The occurrence of this syndrome is not well known in infants.
- Trial name
- NCT01296724
- Testing
- Measure of intravesical pressure
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Rennes University Hospital
Patient Care in Intensive Care Units
Investigating the Effect of Oral Care Frequency on Oral Mucosal Tissue Integrity in Critically Ill Patients.
This study aims to investigate the effect of oral care frequency on oral mucosal tissue integrity in intensive care patients.
- Trial name
- oral care (NCT07635225)
- Testing
- Oral care based on assessment scale, Routine oral care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Balikesir University
Sleep Disturbance, Pediatric Intensive Care Unit
Healing Care Environment and Sleep in Pediatric Intensive Care
This randomized controlled study was conducted to evaluate the effects of non-pharmacological interventions used within the framework of a healing care environment on sleep disturbances in children hospitalized in the pediatric…
- Conditions
- Sleep Disturbance, Pediatric Intensive Care Unit, Sleep Quality, Healing Care Environment
- Trial name
- HEALSLEEP (NCT07626047)
- Testing
- Eye Mask, Audiobook Through Headphones
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Burçak Bahadır
Semi-intensive Care Unit, Evaluation
Health-care Quality in Semi-intensive Care Units
The main aim of this study is to realize a system of continuous evaluation of healthcare quality in semi-intensive care units.
- Conditions
- Semi-intensive Care Unit, Evaluation, Quality
- Trial name
- NCT04676347
- Where
- 18 sites in Italy
- Volunteers
- 39,000 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Pediatric Intensive Care Unit, Comfort
Comfort Intervention in PICU Children
This randomized controlled trial evaluates a family-centered comfort intervention for children hospitalized in a pediatric intensive care unit.
- Conditions
- Pediatric Intensive Care Unit, Comfort, Anxiety in Children, Fear
- Trial name
- CCI-PICU (NCT07441668)
- Testing
- Intervention Family-Centered Comfort, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Pain, Delirium in the Intensive Care Unit
Therapeutic Cuddling in Critically Ill Children
2.1 CONTEXT Pain and agitation are common comorbidities of pediatric critical illness due to both underlying disease processes and ICU related therapies.
- Trial name
- THE ChICKS (NCT07562048)
- Testing
- Therapeutic cuddling, Standard of care
- Where
- Canada
- Volunteers
- 112 people
- Sponsor
- University of Calgary
Pediatrics, Intensive Care Unit
Asia Pediatric Intensive Care Epidemiology and Outcomes Study
The overall objective of this study is to improve the standard of care of critically ill pediatric patients. The specific aims are to describe the clinical profile and outcomes of all admissions to Asian pediatric ICUs, determine…
- Conditions
- Pediatrics, Intensive Care Unit, Critical Illness
- Trial name
- AsiaPedIC (NCT06481644)
- Where
- 2 sites in Singapore, Thailand
- Volunteers
- 10,000 people
- Sponsor
- KK Women's and Children's Hospital
Extremely Premature Infant, Anemia Neonatal
Heterologous Cord Blood-Derived Red Blood Cell for Transfusion in Extremely Preterm Infants
Anemia is a condition in which there are not enough red blood cells to carry oxygen throughout the body. It is very common in extremely preterm infants (born before 28 weeks of pregnancy), and many of these babies require red…
- Conditions
- Extremely Premature Infant, Anemia Neonatal, Blood Transfusion, Umbilical Cord Blood
- Trial name
- NCT07502781
- Testing
- Cord Blood Red Blood Cells, Standard Adult Donor Red Blood Cells
- Where
- Spain
- Volunteers
- 176 people
- Sponsor
- Hospital Clinic of Barcelona
Acute Kidney Injury, Renal Replacement Therapy
Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI
This study follows a group of patients admitted to the PICU who are identified as being at risk for developing acute kidney injury.
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Units
- Trial name
- Taking Focus 2 (NCT03541785)
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Infection Due to Resistant Bacteria, Multi-antibiotic Resistance
Resistant Bacteria in Children in France
This study is observational, multicenter and prospective study for surveillance of the use of new antibiotics in pediatrics for treated pediatrics infections due to multi-resistant bacteria
- Conditions
- Infection Due to Resistant Bacteria, Multi-antibiotic Resistance, Antibiotic Prescription, Risk Factors
- Trial name
- BREF (NCT06036628)
- Where
- France
- Volunteers
- 306 people
- Sponsor
- Association Clinique Thérapeutique Infantile du val de Marne