Clinical trials: Interstitial Nephritis
Urolithiasis, Urologic Diseases
Effectiveness of Drainage by PCN vs. JJ in Patients With Symptoms of Obstructive Kidney Disease Caused by Urolithiasis
To investigate the effectiveness of percutaneous nephrostomy catheter placement versus retrograde double J catheter placement in patients with symptoms of obstructive kidney disease (with either infection and/or pain and/or…
- Conditions
- Urolithiasis, Urologic Diseases, Urinary Calculi, Urinary Obstruction
- Trial name
- STONE (NCT04594161)
- Testing
- Percutaneous Nephrostomy, Double J catheter
- Where
- Netherlands
- Volunteers
- 204 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hospitalized Cases of Angioneurotic Oedema, Pneumonia
Drug Utilization and Safety Events Among Children Using Esomeprazole, Other Proton Pump Inhibitors or H2-receptor Antagonists
The purpose of this study is 1. To describe patient characteristics and drug usage among children that are prescribed esomeprazole for the first time and to compare them with patients who are prescribed other proton pump…
- Conditions
- Hospitalized Cases of Angioneurotic Oedema, Pneumonia, Gastroenteritis, Failure to Thrive
- Trial name
- NCT01338363
- Where
- Netherlands
- Volunteers
- 23,470 people
- Sponsor
- AstraZeneca
Pyelonephritis
Population Pharmacokinetics of Temocillin in Acute Enterobacterial Pyelonephritis in Children
Temocillin, a 6-alpha-methoxypenicillin derivative of ticarcillin, is a narrow-spectrum antibiotic, primarily restricted to Enterobacterales.
- Trial name
- TEMOKID-POP (NCT07070102)
- Testing
- blood samples
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Complicated Urinary Tract Infection, Pyelonephritis
MK-7625A Versus Meropenem in Pediatric Participants With Complicated Urinary Tract Infection (cUTI) (MK-7625A-034)
This study aims to evaluate the safety and tolerability of MK-7625A (ceftolozane/tazobactam) compared with that of meropenem in pediatric participants with cUTI, including pyelonephritis.
- Trial name
- NCT03230838
- Testing
- Ceftolozane/Tazobactam, Meropenem
- Where
- 52 sites in United States, Greece and 8 more
- Volunteers
- 134 people
- Sponsor
- Merck Sharp & Dohme LLC
Otorhinolaryngologic Diseases, Respiratory Tract Infections
Antibiotic Education for Children in an Emergency Care Unit
The purpose of this study is to determine if a patient education in acute condition about the intake of oral solution antibiotic in children under 6 year-old are effective to improve the satisfaction about the therapeutic…
- Conditions
- Otorhinolaryngologic Diseases, Respiratory Tract Infections, Pyelonephritis, Urinary Tract Infections
- Trial name
- ACHEEN (NCT00948779)
- Testing
- antibiotic education for children in an emergency care unit
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pyelonephritis
Effect of Acetylcysteine in Pediatric Acute Pyelonephritis.
In different studies, it has been shown that "antioxidant" utilization has favorable therapeutic effects not only on control of acute symptoms but also on prevention of delayed problems from acute and chronic pyelonephritis.
- Trial name
- NCT02080182
- Testing
- Acetylcysteine
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Urinary Tract Infection, Pyelonephritis
Cranberry-lingonberry Juice Started During Acute Infection in Prevention of Urinary Tract Infections in Children
Cranberry and cranberry-lingonberry juice prevented urinary tract infections in children and in adults in our earlier clinical trials.
- Conditions
- Urinary Tract Infection, Pyelonephritis, Cystitis
- Trial name
- NCT01861353
- Testing
- Cranberry-lingonberry juice
- Where
- Finland
- Volunteers
- 113 people
- Sponsor
- University of Oulu
Urinary Tract Infections in Children
7-day Compared With 10-day Antibiotic Treatment for Febrile Urinary Tract Infections in Children
The investigators aim to assess the effectiveness of a 7-day compared with a 10-day course of antibiotic treatment for febrile urinary tract infections (UTIs) in children.
- Trial name
- NCT03221504
- Testing
- Longer therapy duration, Shorter therapy duration
- Where
- 2 sites in Poland
- Volunteers
- 221 people
- Sponsor
- Medical University of Warsaw
Urinary Tract Infection, Pyelonephritis
Pharmacokinetics of Ciprofloxacin in Pediatric Patients
Measuring serum and urine concentrations of ciprofloxacin after IV and oral administration in children aged 3 months - 17 years who are treated for urinary tract infections.
- Trial name
- NCT02598362
- Testing
- ciprofloxacin
- Where
- 2 sites in Belgium
- Volunteers
- 22 people
- Sponsor
- University Hospital, Ghent
Nephrolithiasis, Glomerulonephritis, Amyloidosis,AKI, CKD, Tubuli Interstitial, Urinary System Disorders in IBD Patients
Affection of Renal and Urinary System in IBD Patients
Detection and classification of different renal and urinary affection in patients with IBD that attended to Assist University Hospitals
- Trial name
- NCT06249243
- Volunteers
- 100 people
- Sponsor
- Assiut University
Pyelonephritis
Short-term Antibiotic Therapy for Pyelonephritis in Childhood
The purpose of this study is to evaluate the efficacy of oral ceftibuten for 7 days versus 10 days in acute pyelonephritis in children.
- Trial name
- STUTI (NCT00724256)
- Testing
- ceftibuten
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- IRCCS Burlo Garofolo
Complicated Urinary Tract Infections or Pyelonephritis
A Safety and Tolerability Study of Doripenem Compared With Cefepime in Children Hospitalized With Complicated Urinary Tract Infections
The purpose of this study is to evaluate the safety and tolerability of doripenem compared to cefepime in children hospitalized with complicated urinary tract infections.
- Trial name
- NCT01110408
- Testing
- Doripenem, Cefepime, Amoxicillin/clavulanate potassium
- Where
- 38 sites in United States, Argentina and 10 more
- Volunteers
- 41 people
- Sponsor
- Janssen Research & Development, LLC
Cystitis / Pyelonephritis / Cystic Fibrosis / Anthrax
Special Drug Use Investigation of Ciproxan Injection in Pediatrics
The objective in this study is collecting post-marketing information on the safety and efficacy of Ciproxan injection under the routine clinical practice.
- Trial name
- NCT02555059
- Testing
- Cipro (Ciprofloxacin, BAYQ3939)
- Where
- Japan
- Volunteers
- 48 people
- Sponsor
- Bayer
Ankle Sprain, Infectious Colitis
Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication
The purpose of this "before-after" prospective multicenter study is to assess the impact of six Patient Information Leaflets (PILs) on Doctor Patient Communication scale (DPC) and adherence scale for common acute illnesses in…
- Conditions
- Ankle Sprain, Infectious Colitis, Diverticulitis, Pyelonephritis
- Trial name
- EDIFIP (NCT02246361)
- Testing
- Patient Information Leaflet (PIL)
- Where
- 2 sites in France
- Volunteers
- 211 people
- Sponsor
- Floralis
Urinary Tract Infection, Pyelonephritis
Risk Factors for Recurrent Urinary Tract Infection in Children
The purpose of this study is to determine clinical and urodynamic risk factors for recurrent urinary tract infection in 5-18 years old children.
- Conditions
- Urinary Tract Infection, Pyelonephritis, Cystitis
- Trial name
- NCT00528476
- Where
- Lithuania
- Volunteers
- 161 people
- Sponsor
- Kaunas University of Medicine
Pyelonephritis
Antibiotic Prophylaxis in Children With Pyelonephritis
Children who present with pyelonephritis undergo many investigations, and long term care to prevent renal damage. The focus is primarily on preventing renal failure however along the way and particularly with children, other…
- Trial name
- NCT00752375
- Testing
- Trimethoprim Sulfamethoxazole
- Where
- Canada
- Sponsor
- University of Alberta
Pyelonephritis
Treatment of Acute Pyelonephritis With Gram Negative Strains in Infants and Children Less Than 3 Years Old
The purpose of this study is to demonstrate the equivalence of the therapeutic efficacy of cefixime by mouth (PO) 10 days (d) and ceftriaxone intravenous route(IV) 4d followed by cefixime PO 6d on renal scars 6 months after a…
- Trial name
- NCT00136656
- Testing
- antibiotic, antibiotics
- Where
- 12 sites in France
- Volunteers
- 700 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Intra Abdominal Infections, Appendicitis Acute
Diagnosis of Abdominal Pain Using RNA Levels: The NATURAL Study
The NATURAL Study is a prospective, observational, pragmatic study of RNA biomarkers of infections to aid in the diagnosis of abdominal pain.
- Conditions
- Intra Abdominal Infections, Appendicitis Acute, Pyelonephritis, Diverticulitis
- Trial name
- NATURAL (NCT07579312)
- Testing
- TruNAV, an RNA-based blood test for host immune activation by infections
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- True Bearing Diagnostics, Inc.
Pyelonephritis, Renal Scars
A Randomized Controlled Trial on Antibiotic Prophylaxis in Children With Vesico-Ureteral Reflux
The aim of this study is to assess the effectiveness of antibiotic prophylaxis in preventing pyelonephritis and in avoiding the appearance of new scars in a sample of children under 36 months with vesico-ureteral reflux (VUR).
- Trial name
- NCT00382343
- Testing
- Sulfamethoxazole/trimethoprim
- Where
- 7 sites in Italy
- Volunteers
- 96 people
- Sponsor
- IRCCS Burlo Garofolo
Glomerular Disease
Pathogenesis of Glomerulosclerosis
The present protocol seeks to advance our understanding of sclerosing glomerular and tubulointerstitial kidney diseases, including but not limited to variants of focal segmental glomerulosclerosis (FSGS) and chronic kidney…
- Trial name
- NCT00001392
- Where
- United States
- Volunteers
- 537 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)