Clinical trials: Interventional Study
Obesity
Randomized, Controlled, Open, Comparative Intervention Study for Obesity Prevention in Children
Randomized, controlled, open, comparative intervention study in 270 children at risk for obesity.Patients will be randomly allocated into one of two behavior intervention groups or control group in ratio of 1:1:1.The study will…
- Trial name
- 4055obesityprv (NCT00438555)
- Testing
- Parents and children group, Parent's group
- Where
- Israel
- Volunteers
- 248 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Family Relations, Parenting
An Online Post-Adoption Family Intervention Using Trust-Based Relational Intervention (TBRI) to Improve Understanding, Well-Being, and Connection in Adoptive Families
The current study aims to examine the effectiveness of an online, self-paced post-adoption intervention to improve understanding, well-being, and connection within adoptive families.To evaluate the effectiveness of this…
- Trial name
- NCT04443504
- Testing
- The Connected Family Series
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Jana Hunsley
Hepatocellular Carcinoma
Computer-assisted Tumor Ablation for Patients With Liver Cancer
In patients with primary liver cancer arising from the liver cells, several treatment options are available according to the stage of the disease.
- Trial name
- NCT03630068
- Testing
- Stereotactic percutaneous image-guided microwave ablation
- Where
- Switzerland
- Volunteers
- 87 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pain Due to Certain Specified Procedures
Single Injection Infromedial Peribulbar Injection in Lacrimal Duct
infromedial injection of 3 ml local anesthetic drugs and assessing the pain during lacrimal duct intubation and probability of false tracking
- Trial name
- NCT04859049
- Testing
- infromedial single injection, medial canthus injection
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Research Institute of Ophthalmology, Egypt
Memory Replay, HippoCamera
A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome
Down syndrome is a chromosomal abnormality associated with significant deficits across multiple cognitive domains, including a disproportionate deficit in hippocampally-dependent memory.
- Trial name
- NCT07008989
- Testing
- Memory replay
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Boston College
Mental Health Wellness 1
Evaluation of Staff COVID-19 Wellbeing Centres in a Healthcare Workplace: COVID-WELL Study
Evaluation of a workplace intervention to implement supported wellbeing centres in a healthcare workplace during and after the COVID-19 pandemic.
- Trial name
- COVID-WELL (NCT04410016)
- Testing
- Staff Wellbeing Centres
- Where
- United Kingdom
- Volunteers
- 819 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Type 1 Diabetes
Feasibility Study of Family Teamwork Peer-Delivery
The purpose of this study is to 1) convene African American and Latino Community Coalitions to adapt Family Teamwork (FT) for school-age youth, and integrate FT with the Smart and Secure Children (SSC) program community-based…
- Trial name
- TEAM (NCT04053504)
- Testing
- Family Teamwork-Peer Delivery
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Baylor College of Medicine
Physical Fitness, Body Image
School-based Multicomponent Intervention on Physical Fitness Related to Health and Body Image
The main purpose of this study is to analyse the effect of a multicomponent intervention, applied during one scholar semester, on body composition, strength, flexibility, cardiorespiratory fitness, lipid and metabolic profile…
- Trial name
- NCT02719704
- Testing
- "MEXA-SE", "Espelho, espelho meu"
- Where
- Brazil
- Volunteers
- 568 people, healthy volunteers welcome
- Sponsor
- Santa Catarina Federal University
Type 1 Diabetes Mellitus, Parent-Child Relations
Feasibility Study of a Behavioral Parent Intervention to Support Self-management in Pediatric Typ 1 Diabetes
This study investigates feasibility and preliminary effects of a new behavioral parent intervention that aims to support and improve pediatric diabetes self-management
- Conditions
- Type 1 Diabetes Mellitus, Parent-Child Relations, Self-management, Behavioral Intervention
- Trial name
- NCT06599840
- Testing
- Parent intervention
- Where
- Sweden
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Childhood Brain Tumor, Childhood Brain Tumors
The FLaME Cognitive Rehabilitation Study for Childhood Brain Tumour
Medical treatments have improved survival rates for children with brain tumours. However, most children experience long-term difficulties with 'cognition' (thinking skills such as memory and paying attention) and cognitive…
- Conditions
- Childhood Brain Tumor, Childhood Brain Tumors, Pediatric Brain Neoplasms, Pediatric Brain Tumor
- Trial name
- FLaME (NCT06770335)
- Testing
- THE FATIGUE, LEARNING, AND MEMORY ENRICHMENT (FLaME) INTERVENTION - Full intervention, THE FATIGUE, LEARNING, AND MEMORY ENRICHMENT (FLaME) INTERVENTION - Cognitive rehabilitation only
- Where
- United Kingdom
- Volunteers
- 36 people
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Anticoagulant Disorders
Management of Direct Oral Anti-Coagulants (DOACs) for Gastrointestinal Endoscopy Procedures
The use of Direct Oral Anti-Coagulants (DOACs) is expanding, but their proper management in patients undergoing endoscopic procedures is still not completely clear. Current European guidelines are based on weak data.
- Trial name
- NCT02734316
- Testing
- endoscopic procedure
- Where
- Italy
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Valduce Hospital
Dental Caries, Oral Health Behavior Change
Assessing the Impact of a Social Media-Based Educational Intervention Using WhatsApp Video Messages on Dental Caries Prevention Knowledge, Oral Hygiene Practices, and Attitudes Toward Dental Health Among Primary School Children Aged 10-12 Years in Public Schools in Cairo Governorate, Egypt: A Quasi-
The goal of this study is to learn if educational videos sent through WhatsApp can improve dental health knowledge, healthy habits, and attitudes in primary school children aged 10 to 12 years in Cairo, Egypt.
- Conditions
- Dental Caries, Oral Health Behavior Change, Oral Hygiene, Oral Health, Knowledge, Attitudes, Practice
- Trial name
- NCT07363317
- Testing
- WhatsApp-Based Dental Health Education for Children
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Rana Mohamed Ahmed Farghal
Respiratory Aspiration
Acceptability and Feasibility of a New Postural Management Night-time Intervention to Improve Respiratory Health of Children With Complex Neuro-disability
This research concerns children with complex neuro-disability. Damage to the developing brain leads to lifelong disturbances in motor control, seizures, cognition, communication, eating and drinking, and behaviour.
- Trial name
- Breathe-Easy (NCT06039852)
- Testing
- Novel Postural Management Night-time Intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Sussex Community NHS Foundation Trust
Attention Deficit Hyperactivity Disorder Combined
Evaluating the Feasibility of FAM-SOTC Intervention for Families of Adolescents With ADHD: Pilot Study
Attention-deficit/hyperactivity disorder (ADHD), is a highly genetic and complex neurological disorder, where disruptive behavior, emotional imbalance, and lack of attention can interrupt with normal development of adolescents…
- Trial name
- NCT04378517
- Testing
- psychosocial education in parents groups, psychosocial parents support, interviews with APN
- Where
- Iceland
- Volunteers
- 23 people
- Sponsor
- University of Iceland
Diabetes, Diabetes Mellitus, Type 2
Observational Study to Assess the Quality of Life and Clinical Outcomes in Subjects Using NovoMix® 30 for the Treatment of Diabetes
This study is conducted in Asia. The aim of this observational study is to evaluate the quality of life and clinical outcomes in subjects using NovoMix® 30 (biphasic insulin aspart 30) for the treatment of diabetes mellitus under…
- Trial name
- IMPROVE Life (NCT00696163)
- Testing
- biphasic insulin aspart 30
- Where
- India
- Volunteers
- 24,975 people
- Sponsor
- Novo Nordisk A/S
Tobacco Cessation
Medium Vs Low Intensity Intervention in Tobacco Cessation and Control in Zari Workers
Zari workers in Mumbai city will be assessed for tobacco consumption habit. They will be divided into 3 arms as - 1) First arm will get Medium intensity tobacco cessation intervention 2) Second arm will get low intensity tobacco…
- Trial name
- ZARI (NCT02103868)
- Testing
- Tobacco Cessation Counseling
- Where
- India
- Volunteers
- 400 people
- Sponsor
- Tata Memorial Hospital
Hemophilia
Safety and Efficacy of FVIIa to Prevent Excessive Bleeding in Hemophilia Patients With Inhibitors Undergoing Major Surgery
This is an interventional, prospective, international, multicenter, single-arm, Phase 3, and sequential efficacy and safety study in adolescents and adults with congenital hemophilia A or B with inhibitors to factor VIII (FVIII)…
- Trial name
- SCOPE HIM (NCT05695391)
- Testing
- Coagulation Factor VIIa (Recombinant)
- Where
- 15 sites in United States, Malaysia and 4 more
- Volunteers
- 2 people
- Sponsor
- Laboratoire français de Fractionnement et de Biotechnologies
Respiratory Function, Pediatric Anesthesia
Effects of Different Inspiratory:Expiratory Ratios on Respiratory and Recovery Outcomes During Dental Procedures Under General Anesthesia in Pediatric Patients
This observational study aims to evaluate the effects of different inspiratory to expiratory (I:E) ratios (1:2 vs. 1:3) during mechanical ventilation in pediatric patients undergoing dental procedures under general anesthesia.
- Conditions
- Respiratory Function, Pediatric Anesthesia, General Anesthesia
- Trial name
- NCT07323420
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC
Breast Cancer
Long-Term Effect of Adolescent Diet on Hormones and Breast Cancer Risk in Women Previously Enrolled in the Dietary Intervention Study in Children
RATIONALE: The amount and type of fat in the diet may affect hormone levels, bone mineral density, and breast density later in life. This may affect the risk of developing breast cancer.
- Trial name
- NCT00458588
- Testing
- physiologic testing, questionnaire administration, breast imaging study
- Where
- 10 sites in United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Fox Chase Cancer Center
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