Clinical trials: Interventional Study
Meconium Obstruction of Prematurity
Saline Enema Administration in Meconium Obstruction of Prematurity and Impact on the Resolution, Feeds, Microbiome, and Gut-brain Axis.
The goal of this clinical trial is to study the effect of twice-daily saline enema (SE) in the treatment obstruction of prematurity (MOP) in infants with the birth weight ≤1.25kg.
- Trial name
- NCT06048614
- Testing
- Saline Enema (SE), Glycerin Suppository
- Where
- 2 sites in Singapore
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Acromioclavicular Joint, Dislocation
A Prospective, Randomised Long-term Follow-up of Operative Versus Non-operative Treatment of Gr. 3 Acromioclavicular Dislocation
The purpose of this study is to compare the long-term clinical and radiological results of operative and conservative treatment of Tossy type 3 acromio-clavicular dislocation.
- Conditions
- Acromioclavicular Joint, Dislocation, Surgical Procedures, Operative
- Trial name
- NCT00840593
- Testing
- Non-surgical group, Surgical group
- Where
- Finland
- Volunteers
- 39 people
- Sponsor
- Kuopio University Hospital
Cardiovascular Diseases, Respiratory Diseases
Study on Intervention Effect of Heat-related Health Risk Early Warning Digital Technology for School-age Children
This cluster randomized trial is conducted in Beijing primary schools to evaluate the efficacy of a WeChat mini-program-based high-temperature early warning intervention on the physical and cognitive health of school-age…
- Conditions
- Cardiovascular Diseases, Respiratory Diseases, Mental Health Disorders, Heat Illness
- Trial name
- NCT07643571
- Testing
- WeChat Mini-program Based Heat Health Risk Early Warning Intervention
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention, China
Thyroid Cancer
This Study is Mainly About Finding Incidence Among Other Factors of Thyroid Cancer in Patient with Benign Disease As MNG to Early Discover of the Malignancy to Save the Patient from Aggressive Procedure
The purpose of the present study was to evaluate the prevalence of thyroid cancer in patients who had thyroidectomy for MNG, and analyze patient-related parameters to identify type and risk factors associated with incidental…
- Trial name
- NCT06730971
- Testing
- Total thyroidectomy
- Volunteers
- 300 people
- Sponsor
- Asmaa Mohamed Emam
Pilonidal Sinus of Natal Cleft
Long-term Outcome After Pit-pick for Simple Pilonidal Sinus Disease
Single-center cohort study of long-term results after pit-pcik for pilonidal sinus disease.
- Trial name
- NCT05027607
- Testing
- Bascom's pit-pick
- Where
- Denmark
- Volunteers
- 158 people
- Sponsor
- Nordsjaellands Hospital
Emotional Stress
Dog-Assisted Therapy in Children During Blood or Dental Extraction.
The purpose of the present study is to evaluate the efficacy of Animal Assisted Therapy (AAT) during blood extraction or dental procedures in a Primary Care Pediatric Service.
- Trial name
- Extra-can (NCT06468111)
- Testing
- Animal Assisted Therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Obesity
Nutrigenomics And Children Obesity: A Moderate Weight Loss Intervention Study
The consumption of diets enriched in proteins (legumes and fish) or antioxidant (fruits and vegetables) could have beneficial effects beyond those of the caloric restriction on biomarkers of the inflammatory and oxidative status.
- Trial name
- NUGENOI (NCT01329367)
- Testing
- Control group, Protein group, Antioxidant group
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Overweight and Obese Children
The Effectiveness of the Health Promoting School Intervention Model in Reducing Overweight and Obesity Among School Children in Indonesia: a Mixed-Methods Protocol Study
The prevalence of obesity in children is increasing rapidly, Among children aged 5-12 years, 18.8% have severe overweight, comprising 10.8% who are obese and 8.8% who are over.
- Trial name
- NCT06601348
- Testing
- Nutrition education, physical activity intervention, and health promoting school model trials
- Where
- 2 sites in Indonesia
- Volunteers
- 500 people
- Sponsor
- Gadjah Mada University
Hyperammonemia, Methylmalonic Acidemia
An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics
To obtain short-term and long-term clinical safety information, in pediatric and adult patients with PA and MMA treated with Carbaglu®.
- Conditions
- Hyperammonemia, Methylmalonic Acidemia, Propionic Acidemia
- Trial name
- NCT05040178
- Testing
- Carglumic Acid
- Where
- 5 sites in United States
- Volunteers
- 20 people
- Sponsor
- RECORDATI GROUP
Acute Respiratory Failure
Study on Ventilation Distribution With Electrical Impedance Tomography for Paediatric Respiratory Failure
Electrical impedance tomography (EIT) is a non-invasive, bedside monitoring technique that provides continuous, real-time information about the regional distribution of the ventilation.
- Trial name
- PELUCHE1 (NCT05347563)
- Testing
- Electrical impedance tomography
- Where
- 4 sites in France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
Epilepsy
Efficacy and Safety of Levetiracetam in Routine Clinical Practice in Czech and Slovak Republics, Hungary, and Romania.
To evaluate, over 1 year period, the efficacy and safety of newly prescribed levetiracetam as add-on treatment (POS, myoclonoc seizures in JME and PGTCS in IGE) or primary monotherapy (partial onset seizures) in adult and…
- Trial name
- NCT00614549
- Volunteers
- 2,569 people
- Sponsor
- UCB Pharma
Early Gastric Cancer
the Train the Trainer (TTT) Plan, to Improve the Young Endoscopist's Ability to Find the Early Gastric Cancer
AIM Verified if the first stage of the Train the trainer (TTT)plan could improve the young endoscopist's ability to detect the early gastric cancer（EGC）. METHOD 1.
- Trial name
- NCT02385578
- Testing
- an educational intervention
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Tic Disorders
Clinical Efficacy and Change of Life Quality Through Using the Comprehensive Behavioral Intervention Treatment for Tics
Study on the clinical efficacy and change of life quality through using the Comprehensive Behavioral Intervention Treatment for Tics (CBIT)
- Trial name
- NCT04765085
- Testing
- comprehensive behavioral intervention therapy (CBIT), Aripiprazole 5Mg Oral Tablet
- Sponsor
- Children's Hospital of Fudan University
Minor Head Injury
The Value of the Canadian CT Head Rule and the New Orleans Criteria in Minor Head Trauma
The New Orleans Criteria (NOC) and the Canadian CT Head Rules (CCHR) have been developed to decrease the number of normal computed tomography (CT) in mild head injury (MHI).
- Trial name
- NCT01619943
- Testing
- no intervention
- Where
- 3 sites in Tunisia
- Volunteers
- 1,600 people
- Sponsor
- University of Monastir
Psychological Adjustment, Cancer
Enhancing Adjustment to Parental Cancer: Short-term Counselling for Families
A parental cancer diagnosis challenges the family's stability and the parent-child relationship. It may impact the children's well-being, so that about one third of them develop clinically relevant levels of psychological…
- Trial name
- NCT03097458
- Testing
- Short-term Counselling for Families
- Where
- Switzerland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Obstructive Sleep Apnea Syndrome in Children
ATT Compared With ATE in OSAS Children
Non-inferiority hypothesis; adenotonsillotomy is equally good as adenotonsillectomy in treating obstructive sleep apnea syndrome (OSAS) in children after one, three and ten years.
- Trial name
- RCT ATE/ATT (NCT01676181)
- Testing
- Adenotonsillectomy, Adenotonsillotomy
- Where
- Sweden
- Volunteers
- 79 people
- Sponsor
- Karolinska University Hospital
Haemophilia A, Haemophilia A With Inhibitors
A Study Following People With Haemophilia A and B, With or Without Inhibitors, When on Usual Treatment (Explorer™6)
This study will collect data on bleeds and data related to quality of life in people with severe congenital (a disease existing from birth) haemophilia A and B, with or without inhibitors.
- Conditions
- Haemophilia A, Haemophilia A With Inhibitors, Haemophilia B, Haemophilia B With Inhibitors
- Trial name
- explorer™6 (NCT03741881)
- Testing
- No treatment given
- Where
- 143 sites in United States, Algeria and 34 more
- Volunteers
- 231 people
- Sponsor
- Novo Nordisk A/S
School-based Intervention, Mindfulness-based Intervention
PACE Study: School-Based Mindfulness and Compassion Interventions for Children
This study aims to evaluate the effects of three school-based interventions focused on mindfulness, compassion, and social-emotional learning on children's psychological well-being and higher-order cognitive functions.
- Conditions
- School-based Intervention, Mindfulness-based Intervention, Compassion, Emotion Regulation
- Trial name
- PACE (NCT07398781)
- Testing
- Mindfulness-based intervention, Social Emotional Learning Program, Compassion-focused Training
- Where
- 4 sites in Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris
Rheumatoid Arthritis AND Apical Periodontitis
Effect of Endodontic Treatment on Inflammatory Markers, Disease Activity and Periapical Healing in Rheumatoid Arthritis Patients With Apical Periodontitis : A Prospective Interventional Study
SUMMARY TITLE: "Effect of endodontic treatment on inflammatory markers, disease activity and periapical healing in rheumatoid arthritis patients with apical periodontitis" RATIONALE: Chronic inflammation plays a pivotal role in…
- Trial name
- NCT06433232
- Testing
- ROOT CANAL TREATMENT
- Where
- India
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Autism Spectrum Disorder, Language Delay
Implementation of Incredible Years for Autism and Language Delay Program in Spain
Children with autism spectrum disorders (ASD) usually present coexisting problems in emotion and behavior regulation, similarly as premature children with communication or socialization difficulties.
- Conditions
- Autism Spectrum Disorder, Language Delay, Prematurity
- Trial name
- FS (NCT04358484)
- Testing
- Incredible Years - ASD and Language Delay®
- Where
- Spain
- Volunteers
- 72 people
- Sponsor
- Fundació Sant Joan de Déu
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