Clinical trials: Interventional Study
Hunter Syndrome
A Study of Elaprase in Children and Adults With Hunter Syndrome (Mucopolysaccharidosis II) in India
The main aim of this study is to learn more about the safety profile of Elaprase in Indian children and adults with hunter syndrome.
- Trial name
- NCT05058391
- Testing
- Elaprase
- Where
- 5 sites in India
- Volunteers
- 5 people
- Sponsor
- Takeda
Virtual Reality, Pain
Virtual Reality vs Passive Distraction for Pain Management
Background: Outpatient pediatric orthopedic procedures such as percutaneous pins removal and sutures are considered painful and generate significant stress and anxiety in children.
- Conditions
- Virtual Reality, Pain, Pain Perception, Pain Management
- Trial name
- NCT03680625
- Testing
- Passive Distraction, Virtual Reality Distraction
- Where
- 3 sites in Canada
- Volunteers
- 188 people
- Sponsor
- St. Justine's Hospital
Agitation, Anesthesia
Use of Dexmedetomidine to Reduce Emergence Delirium Incident in Children
Emergence delirium (ED) from general anesthesia posts risk and harm to pediatric population undergo general anesthesia. The purpose of the study is to compare the use of dexmedetomidine versus placebo in reducing the incidence…
- Conditions
- Agitation, Anesthesia, Pediatrics
- Trial name
- DexPeds (NCT00857727)
- Testing
- Dexmedetomidine, Saline
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Parent-Child Relations, Preterm Birth
Bilateral Infant Stimulation Study
This study will investigate stress that parents of children admitted to the neonatal intensive care unit (NICU) experience. Investigation of a novel intervention of using bilateral alternating stimulation to reduce parental…
- Conditions
- Parent-Child Relations, Preterm Birth, Stress Reaction, Hospitalism in Children
- Trial name
- BLISS (NCT06353243)
- Testing
- Bilateral alternating stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Oregon Health and Science University
Cardiovascular Diseases
A Behavior Intervention Study on Cardiovascular Health Among Chinese Obese Schoolchildren
The aim of this study is to evaluate the effects of comprehensive behavior on cardiovascular health among obese schoolchildren. The intervention methods include dietary instruction and exercise intervention.
- Trial name
- NCT02773823
- Testing
- Intervention group
- Where
- China
- Volunteers
- 190 people
- Sponsor
- Wuhan University
Low Birth Weight Infants, Preterm Infants
Predictors and Outcomes of Kangaroo Mother Care: A Quasi-Experimental Study in Pakistan
This quasi-experimental study evaluated the impact of Kangaroo Mother Care (KMC) versus Conventional Care (CC) on the growth, developmental milestones, breastfeeding, vaccination, and mortality of low birth weight infants in…
- Trial name
- NCT06559020
- Testing
- Kangroo mother care
- Where
- Pakistan
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Indication for Care or Intervention Related to Labor or Delivery With Baby Delivered
Incidence of Difficult Airway and Difficult Neuraxial Placement in Obstetric Patients
Anesthesiologists commonly administer pain relief during labor or providing anesthesia for cesarean delivery. Two main methods are used to achieve these goal: "Regional anesthesia" where the mother is given medication through a…
- Trial name
- DADB (NCT02193542)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anticoagulants, Intention
Pharmacists' Intervention in Patients Using Novel Oral Anticoagulants：A Study on Behavioral Patterns
Novel oral anticoagulant drugs (NOACs) are now increasingly used in clinical practice. Although there are outstanding advantages of NOACs, there are also some shortcomings in use.
- Conditions
- Anticoagulants, Intention, Behavioral Symptoms
- Trial name
- NCT03670446
- Testing
- Pharmacists' intervention
- Where
- 2 sites in China
- Volunteers
- 400 people
- Sponsor
- Cui Yimin
Epidermolysis Bullosa, Dystrophic, Epidermolysis Bullosa, Junctional
A Study to Assess the Incidence of Skin Cancers in Patients With Epidermolysis Bullosa Receiving Filsuvez
In patients with epidermolysis bullosa (EB), collagen does not form properly, so their skin is very fragile and blisters easily. Such patients are also at greatly increased risk of developing skin cancers.
- Trial name
- FOSteR (NCT06423573)
- Testing
- Filsuvez
- Where
- 12 sites in United States, France and 4 more
- Volunteers
- 170 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Tuberculosis
Community-based Tuberculosis Tracing and Preventive Therapy
The many gaps observed in the cascade of care of tuberculosis (TB) child contacts occur mostly in the screening, preventive therapy (PT) initiation and PT completion steps and the main drivers of these gaps are considered to be…
- Trial name
- CONTACT (NCT03832023)
- Testing
- Screening and initiating preventive therapy in communities
- Where
- 25 sites in Cameroon, Uganda
- Volunteers
- 1,400 people
- Sponsor
- Elizabeth Glaser Pediatric AIDS Foundation
Psychotic Disorders
This Study Tests Whether BI 409306 Prevents Patients With a Specific Type of Mental Illness (Attenuated Psychosis Syndrome) From Becoming Worse. This Study Looks at How Well Patients Tolerate the Medicine and How Effective it is Over 1 Year
This is a study in people between 16 and 30 years of age who have a specific type of mental illness called attenuated psychosis syndrome (APS).
- Trial name
- NCT03230097
- Testing
- BI 409306
- Where
- 33 sites in United States, Canada and 2 more
- Volunteers
- 50 people
- Sponsor
- Boehringer Ingelheim
Child Abuse, Self-control
Coaching Alternative Parenting Strategies (CAPS) Study
This is a randomized, controlled trial (RCT) of Parent-Child Interaction Therapy (PCIT) designed to test the effects of PCIT on self-regulation and behavior in child maltreating (CM) parents and their elementary-school children.
- Conditions
- Child Abuse, Self-control, Parenting
- Trial name
- CAPS (NCT02684903)
- Testing
- Parent Child Interaction Therapy
- Where
- United States
- Volunteers
- 408 people
- Sponsor
- University of Oregon
Osteoporosis
Vitamin D Osteoporosis Long-Term Care Study
The research question is, does a multifaceted, multidisciplinary intervention including small groups, chart audits and point of care tools, increase the number of people receiving optimal vitamin D therapy in the long term care…
- Trial name
- ViDOS (NCT01398527)
- Testing
- Educ sessions & LTC Osteoporosis toolkit
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- McMaster University
Childhood Asthma, Asthma Control
Pollution Intervention to Impact Kids Asthma Study
The goal of this clinical trial is to learn if adding Air Quality Index (AQI) information to asthma action plans works to improve asthma outcomes in children.
- Conditions
- Childhood Asthma, Asthma Control, Asthma Exacerbation, Air Pollution, Risk Reduction Behaviors
- Trial name
- PIKAS (NCT07261423)
- Testing
- EPA-AQI, Commerical-AQI, Education and plan
- Where
- United States
- Volunteers
- 351 people
- Sponsor
- University of Pittsburgh
Sedation
A Study to Learn About the Study Medicine - Precedex in Children From Japan.
The purpose of this study is to look at the safety of Precedex when it was used to calm children at procedures or tests under actual medical practice in Japan.
- Trial name
- NCT06085573
- Testing
- Dexmedetomidine Hydrochloride
- Where
- Japan
- Volunteers
- 111 people
- Sponsor
- Pfizer
Spectator Intervention
PRECEDE PROCEED Model and Recycling Awareness
This research is a randomized controlled experimental study. The aim of the research is to determine the effect of a recycling program based on the Precede Proceed Model on the recycling awareness and behaviors of 6th-grade…
- Trial name
- NCT07591870
- Testing
- Recycling Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gazi University
Cataract
Risk of Radiation-induced Cataracts Among Interventional Cardiology Staff
The goal of the present study is to evaluate the prevalence of radiation-associated lens opacities among interventional cardiology staff members (such as physicians, technicians, and nurses) and determine its association with…
- Trial name
- IC-CATARACT (NCT02837562)
- Testing
- Slit lamp eye examination
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Secondary Malignancies of T-cell Origin
A Non-Interventional Study PASS to Characterize Secondary Malignancies of Tcell Origin Following Tisagenlecleucel Therapy
The study aims to provide an adequate procedural framework to support and facilitate collection of existing participant samples from patients who were diagnosed with secondary malignancy of T-cell origin any time after…
- Trial name
- Lythesia (NCT07378969)
- Where
- 4 sites in Japan
- Volunteers
- 30 people
- Sponsor
- Novartis Pharmaceuticals
Psychosomatic Disorder, Mental Disorder
Effectiveness and Equivalence of an Internet-based Virtual Classroom Intervention for Psychosomatic Aftercare
Outpatient psychosomatic aftercare after inpatient rehabilitation pursues the goal of helping patients to transfer the achieved rehabilitation result in everyday life and professional life.
- Trial name
- NCT04989842
- Testing
- Curriculum Hannover
- Where
- Germany
- Volunteers
- 6,023 people, healthy volunteers welcome
- Sponsor
- Dr. Becker Hospital Group
Muscular Atrophy, Spinal
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy
This is an open-label, single-arm, multicenter clinical study to evaluate the effectiveness and safety of risdiplam administered as an early intervention in pediatric participants with spinal muscular atrophy (SMA) and 2 SMN2…
- Trial name
- HINALEA 1 (NCT05861986)
- Testing
- Risdiplam
- Where
- 16 sites in United States, Germany and 2 more
- Volunteers
- 28 people
- Sponsor
- Hoffmann-La Roche
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