Clinical trials: Intestinal Infection
Perforated Appendicitis
Diagnostic Value of Hyperbilirubinaemia as a Predictive Factor for Appendiceal Perforation in Acute Appendicitis
The values of laboratory examinations which are useful for the diagnoses of appendicitis are white blood cell count (WBC), C-reactive protein (CRP) and erythrocyte blood sedimentation rate (ESR).
- Trial name
- NCT00677417
- Volunteers
- 538 people
- Sponsor
- Ruhr University of Bochum
Perioperative Hyperoxygenation, Wound Infection
Effect of Peri-operative Supplemental Oxygen in Wound Infection After Appendectomy
The study evaluates the role of supplemental hyper-oxygenation given perioperatively on wound site infection after appendectomy.
- Trial name
- NCT02687217
- Testing
- oxygen
- Volunteers
- 60 people
- Sponsor
- Lady Hardinge Medical College
Acute Kidney Injury, Sepsis
Novel Biomarkers for Early Renal Injury in Children With Sepsis
Toxicosis often leads to multiple organ failure (MODS), with the kidney being the primary target organ due to its sensitivity to infection and ischemia.
- Conditions
- Acute Kidney Injury, Sepsis, Gout Flare
- Trial name
- NCT06197828
- Testing
- This study is an observational studie which have no intervention
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Cryptosporidiosis, HIV Infections
A Study to Evaluate the Use of Nitazoxanide to Treat Cryptosporidiosis
The purpose of this study is to see if nitazoxanide (NTZ) can be used to treat AIDS patients suffering from cryptosporidiosis (diarrhea caused by the parasite Cryptosporidium).
- Trial name
- NCT00002158
- Testing
- Nitazoxanide
- Where
- United States
- Sponsor
- Romark Laboratories L.C.
Appendicitis
Structured Management of Patients With Suspicion of Appendicitis Using a Clinical Score and Selective Imaging
Patients with acute abdominal pain and suspicion of appendicitis are common. The management of these patients is controversial with large variations between hospitals.
- Trial name
- STRAPPSCORE (NCT00971438)
- Testing
- Diagnostic imaging
- Where
- Sweden
- Volunteers
- 1,312 people
- Sponsor
- Ryhov County Hospital
Sepsis, Necrotizing Enterocolitis
Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis
The purpose of the study is to determine whether vitamin A can improve survival and facilitate recovery from sepsis and necrotizing enterocolitis in hospitalized neonates.
- Conditions
- Sepsis, Necrotizing Enterocolitis, Meningitis, Pneumonia
- Trial name
- NCT00707785
- Testing
- Vitamin A
- Where
- Bangladesh
- Volunteers
- 424 people
- Sponsor
- Johns Hopkins University
Perforated Appendicitis
Study on Laparoscopic Operation for Perforated Appendicitis
The purpose of this study is to conduct a prospective observational study for the open approach and laparoscopic approach for perforated appendicitis.
- Trial name
- NCT00677989
- Testing
- Laparoscopic appendectomy, Open appendectomy
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Far Eastern Memorial Hospital
Sepsis, Necrotising Enterocolitis Neonatal
Integrated Predictive Monitoring for Sepsis and Necrotizing Enterocolitis
Behind the scenes pilot trial in the computer lab involving chart review to use neonatal intensive care unit data to create computer models predicting sepsis and necrotizing enterocolitis in very small premature infants
- Trial name
- PREMO (K) (NCT07254559)
- Testing
- No Intervention: Observational Cohort
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Virginia
Diagnosis of Acute Appendicitis in Children
Urinary 5-HIAA for Diagnosis of Acute Appendicitis in Children, Does it Help?
it is randomized control study. two groups of children (n=191) were divided into two groups A and B. Group A included children subjected to the classical protocol of diagnosis of acute appendicitis.
- Trial name
- NCT04527263
- Testing
- measurement of urinary 5-HIAA
- Where
- Egypt
- Volunteers
- 191 people
- Sponsor
- Tanta University
Celiac Disease
Response to Hepatitis B Vaccine in Celiac Disease Patients
Celiac disease and infection with hepatitis B virus (HBV) are very prevalent worldwide and carry a high morbidity rate. It has been recently shown that patients with celiac disease very often fail to develop immunity after…
- Trial name
- NCT00739128
- Testing
- hepatitis B vaccine (EngerixB)
- Where
- Israel
- Volunteers
- 210 people
- Sponsor
- Shaare Zedek Medical Center
Appendicitis
Low vs. Standard Dose CT for Appendicitis Trial
To determine whether low-dose (LD) CT is noninferior to standard-dose (SD) computed tomography (CT) as the first-line imaging test in adolescents and young adults in regard to negative appendectomy rate (NAR).
- Trial name
- LOCAT (NCT01925014)
- Testing
- Diagnostic CT with low-dose radiation, Diagnostic CT with standard-dose radiation
- Where
- 20 sites in South Korea
- Volunteers
- 3,074 people
- Sponsor
- Kyoung Ho Lee, MD
Appendicitis
Peri-operative Analgesia for Single-incision Laparoscopic Appendectomy
Laparoscopic appendectomy is a very common intervention in pediatric surgery. To improve outcomes, some teams have developed the use of single-site laparoscopic appendectomy (SILAP).
- Trial name
- PAMAL (NCT05773521)
- Testing
- SILAP (single incision laparoscopic appendectomy)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- University Hospital, Angers
Infectious Disease, Children, Only
Prebiotic Fructans on the Incidence of Acute Infectious Diseases in Children
The study aims to explore whether prophylactic dietary supplementation with prebiotic inulin-type fructans is able to influence the intestinal microbiota and the frequency of infectious disease episodes in kindergarten children…
- Conditions
- Infectious Disease, Children, Only, Diet Modification
- Trial name
- NCT03241355
- Testing
- prebiotic inulin-type fructan
- Volunteers
- 258 people, healthy volunteers welcome
- Sponsor
- Beneo-Institute
Perforated Appendicitis
Irrigation Versus No Irrigation for Perforated Appendicitis
The purpose is to quantify the effect of irrigation during laparoscopic appendectomy for perforated appendicitis.
- Trial name
- NCT00854815
- Testing
- Irrigation, No Irrigation
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Children's Mercy Hospital Kansas City
Diarrhea, Shigella
Multidrug Resistant Shigella Infection in Bangladesh
The purpose of this project is to systematically collect clinical and nutritional outcomes information on patients treated for Shigella infection so that physicians and clinical laboratories can better define which Shigella…
- Trial name
- NCT03778125
- Where
- Bangladesh
- Volunteers
- 2,000 people
- Sponsor
- University of Virginia
Appendicitis Acute
Laparoscopic Versus Open Appendectomy Prospective Randomized Control Study
laparoscopic versus open appendectomy prospective randomized control study.Both surgical methods are safe and well established in clinical practice but there has been a controversy about which surgical procedure is the most…
- Trial name
- NCT05611489
- Testing
- Open appendectomy, Conventional Lap appendectomy
- Volunteers
- 70 people
- Sponsor
- Abanoub Atif Fawzy
Human Papillomavirus Infection, HPV
Human Papillomavirus in Young People Epidemiological Research 3
Anal cancer is overrepresented among gay, bisexual and other men who have sex with men (MSM), particularly those living with HIV.
- Conditions
- Human Papillomavirus Infection, HPV, HPV Infection, Anal Cancer
- Trial name
- HYPER3 (NCT05587725)
- Where
- Australia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Monash University
Cryptosporidiosis, HIV Infections
A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by Cryptosporidium
To determine the frequency of complete, marked, and partial clinical responses in patients with cryptosporidiosis treated with 6 weeks of NTZ versus 21 days of placebo.
- Trial name
- NCT00001081
- Testing
- Nitazoxanide
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Appendicitis Acute, Disbiosis
Differences In Microbiota Profiles Of Pediatric Appendicitis Cases
The microbial profile varies between simple appendicitis (SA) and complicated appendicitis (CA) cases. An appendectomy has been noted to temporarily diminish gut bacterial diversity.
- Conditions
- Appendicitis Acute, Disbiosis, Complicated Appendicitis, Simple Appandiscitis
- Trial name
- NCT07860307
- Testing
- Appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Appendicitis
Is Interval Appendectomy Necessary?
Appendicitis is one of the most common surgical problems in children, with 20-35% of patients having perforated by the time they present to a doctor. In these cases, the patient is often treated non-surgically with antibiotics.
- Trial name
- NCT01853683
- Testing
- Conservative Management, Operative Management
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- Children's Hospital of Eastern Ontario