Clinical trials: Intestinal Infection
Cryptosporidiosis, HIV Infections
A Study to Evaluate the Use of Nitazoxanide to Treat Cryptosporidiosis
The purpose of this study is to see if nitazoxanide (NTZ) can be used to treat AIDS patients suffering from cryptosporidiosis (diarrhea caused by the parasite Cryptosporidium).
- Trial name
- NCT00002158
- Testing
- Nitazoxanide
- Where
- United States
- Sponsor
- Romark Laboratories L.C.
Autoimmune Disease, Juvenile Idiopathic Arthritis
Immunogenicity of HPV Vaccine in Immunosuppressed Children
Genital HPV is the necessary cause for cervical cancer, as well as a major contributing cause of several other cancers and conditions. There are now effective vaccines against the main oncogenic HPV types, HPV16 and 18.
- Conditions
- Autoimmune Disease, Juvenile Idiopathic Arthritis, Inflammatory Bowel Disease, Evidence of Liver Transplantation
- Trial name
- NCT02263703
- Testing
- Quadrivalent HPV vaccine
- Where
- Australia
- Volunteers
- 55 people
- Sponsor
- The University of New South Wales
Appendicitis Acute, Gangrenous Appendicitis
Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial.
PHASE II-III CLINICAL TRIAL TO EVALUATE THE SAFETY, EFFECTIVENESS AND EFFICIENCY OF DISCHARGE TO OUTPATIENT SURGERY IN PATIENTS WITH ACUTE GANGRENOUS APPENDICITIS UNDERGOING EMERGENCY SURGERY.
- Trial name
- PENDI-CSI II (NCT07521969)
- Testing
- outpatient surgery, Hospitalization
- Where
- Spain
- Volunteers
- 122 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Lower Abdominal Pain, Right Iliac Fossa Pain
Non Operative Treatment for Acute Appendicitis
Case control studies that randomly assign patients to either surgical or non-surgical treatment yield a relapse rate of approximately 14% at one year.
- Conditions
- Lower Abdominal Pain, Right Iliac Fossa Pain, Acute Appendicitis
- Trial name
- NOTA (NCT01096927)
- Testing
- Amoxicillin and Clavulanic Acid
- Where
- Italy
- Volunteers
- 160 people
- Sponsor
- Maggiore Bellaria Hospital, Bologna
Premature Birth, Neonatal Hypoglycemia
Higher-Dose Dexamethasone Improves Breathing and Shortens NICU Stay in Preterm Babies
The goal of this observational study was to compare two doses of dexamethasone given to pregnant women at risk of preterm birth. Dexamethasone is a medicine used before birth to help a baby's lungs mature.
- Conditions
- Premature Birth, Neonatal Hypoglycemia, Maternal Infection During Pregnancy, Neurodevelopmental Disorder of Foetus
- Trial name
- NCT07765329
- Testing
- Dexamethasone 12 mg Every 12 Hours, Dexamethasone 6 mg Every 12 Hours
- Where
- Indonesia
- Volunteers
- 200 people
- Sponsor
- Stella Maris Women and Children Hospital
Malnutrition, Diarrhea
WASH Benefits Bangladesh
Brief Summary: The purpose of this study is to measure the independent and combined effects of interventions that improve water quality, sanitation, hand washing, and nutrition on child growth and development in the first years…
- Conditions
- Malnutrition, Diarrhea, Child Development
- Trial name
- NCT01590095
- Testing
- Water quality, Sanitation, Hand washing
- Where
- Bangladesh
- Volunteers
- 5,040 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Cholera, Water-Related Diseases
Preventative Intervention for Cholera for 7 Days
The first objective of our study is to develop a theory-driven evidence-based targeted water, sanitation, and hygiene (WASH) intervention for household members of diarrhea patients in South Kivu, Democratic Republic of the Congo…
- Conditions
- Cholera, Water-Related Diseases, Diarrhea Infectious
- Trial name
- PICHA-7 (NCT05166850)
- Testing
- PICHA7 mHealth program, Standard Arm
- Where
- 2 sites in Democratic Republic of the Congo
- Volunteers
- 2,900 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Appendicitis
Perforated Appendicitis With Delayed Presentation
There is no consensus among pediatric surgeons regarding the optimal treatment for children with complicated appendicitis with delayed diagnosis.
- Trial name
- NCT01068288
- Testing
- Laparoscopic or open appendectomy, Expectant Management
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- The Hospital for Sick Children
Amebiasis, Cryptosporidiosis
Parasitic Infections of the Gastrointestinal Tract
This protocol offers diagnosis and standard medical treatment for various parasitic gastrointestinal infections. Gastrointestinal parasites are either worms (helminths) or one-celled animals called protozoans which live in the…
- Conditions
- Amebiasis, Cryptosporidiosis, Giardiasis, Parasitic Disease
- Trial name
- NCT00001162
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Colectomy, Appendicitis
Colonic Resections in Patients With Suspected Appendicitis
Although many reports have been published on colonic resections in patients with suspected appendicitis and the diseases that cause the decision to resect the colon have been identified and their proper treatments have been…
- Trial name
- NCT00888888
- Testing
- Right hemicolectomy with or without primary anastomosis
- Where
- Chile
- Volunteers
- 87 people
- Sponsor
- Cirujanos la Serena
Cryptosporidiosis
A Study to Characterize the Clinical Presentation and Course of Cryptosporidium in Pediatric Participants
This study aims to characterize the pediatric cryptosporidiosis disease profile with respect to clinical presentation.
- Trial name
- NCT07716410
- Where
- 4 sites in Kenya, Malaysia and 1 more
- Volunteers
- 30 people
- Sponsor
- Novartis Pharmaceuticals
Microsporidiosis Intestinal, Heart Transplant Infection
Intestinal Microsporidiosis in French Heart Transplant Recipients (CARMIC)
The investigators propose to carry out a national retrospective study to collect epidemiological, biological, clinical and therapeutic data on microsporidiosis among heart transplant patients.
- Trial name
- CARMIC (NCT06986980)
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Clermont-Ferrand
Necrotizing Enterocolitis (NEC)
NETs: Protection or Harm in Neonatal Inflammation or Infection
This is a prospective in vitro cell biology study of polymorphonuclear leukocyte (PMN) protein synthesis in response to PAF. PMNs from cord blood of premature human infants at risk for NEC (birth weight between 501 - 1500 grams)…
- Trial name
- NCT00747851
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- University of Utah
Dysentery Amebic
Immunochromatography Versus Microscopy for Diagnosis of Entamoeba Histolytica/Dispar Infection.
Amoebiasis, an infection by the protozoan parasite Entamoeba histolytica is globally considered as the third leading parasitic cause of human mortality besides malaria and schistosomiasis. It is estimated that E.
- Trial name
- NCT04759937
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Incisional Hernia, Incision Infection
Total 102 Natural Orifice Specimen Extractions Following Laparoscopic Colorectal Resections
In the development of surgical technique, laparoscopic surgery has created a major breaking point. Although laparoscopy (decreased hospital stay, decreased incisional hernia and wound infection rate…) provides a remarkable…
- Trial name
- NCT04394988
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Inonu University
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Necrotizing Enterocolitis, Sepsis
The Role of Lactobacillus Reuteri in Preventing Necrotizing Enterocolitis (NEC) in Pre-term Infants
The purpose of this study is to compare the effectiveness of L. Reuteri with placebo in prevention of NEC in children, as according to my knowledge, there is limited work is done nationally and internationally.
- Trial name
- NEC (NCT04541771)
- Testing
- Lactobacillus Reuteri DSM 17938
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital and Institute of Child Health, Multan
Health Behavior, Child Development
Dietary Modulation of Gut Microbiota in Overweight/Obese Adolescents and COVID-19 Infection
Probiotic intervention has been currently suggested to provide supportive benefits in promoting health, including alleviating disease symptoms, protecting against diarrhea and respiratory infection, affecting growth and…
- Conditions
- Health Behavior, Child Development, Adolescent Obesity
- Trial name
- DIVINE (NCT05623007)
- Testing
- Probiotics, Counselling on healthy eating, physical activity, and psychosocial stimulation
- Where
- Indonesia
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Inflammatory Bowel Diseases, Clostridium Infections
Study on Clostridium Difficile Infection in Chinese Patients With Inflammatory Bowel Disease
In recent years, the incidence of Inflammatory Bowel Disease (IBD) has been increasing in China, which poses great challenges and burdens to the medical community due to its unknown etiology, recurrence and incurability.
- Trial name
- NCT04179201
- Where
- 6 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
HIV Infection, Nematode Infection
Study of Patients With Strongyloides Stercoralis Infection
This study will explore faster and easier ways to detect infection with the intestinal parasite Strongyloides stercoralis and learn more about the conditions under which it causes serious disease.
- Conditions
- HIV Infection, Nematode Infection, Strongyloidiasis
- Trial name
- NCT00001245
- Where
- United States
- Volunteers
- 650 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)