Clinical trials: Intestinal Infection
Gastroesophageal Reflux Disease, Gastritis
Analysis of Biopsies From the Upper Gastrointestinal Tract
Multicenter study to correlate histological findings in the upper gastrointestinal tract with endoscopic and clinical data.
- Trial name
- histoGERD (NCT01576289)
- Testing
- Histological analysis
- Where
- Austria
- Volunteers
- 600 people
- Sponsor
- Medical University of Graz
Pain, Postoperative, Appendicitis
Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children
Blockage of the transverse abdomen (TAP) promotes excellent analgesia of the abdominal wall and the parietal peritoneum. The TAP block could advange the postoperative pain of Appendectomy in children.
- Trial name
- NCT03005808
- Testing
- Ropivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil Albert Sabin
Perforated Appendicitis
Diagnostic Value of Hyperbilirubinaemia as a Predictive Factor for Appendiceal Perforation in Acute Appendicitis
The values of laboratory examinations which are useful for the diagnoses of appendicitis are white blood cell count (WBC), C-reactive protein (CRP) and erythrocyte blood sedimentation rate (ESR).
- Trial name
- NCT00677417
- Volunteers
- 538 people
- Sponsor
- Ruhr University of Bochum
Microbial Colonization
Probiotics and Intestinal Microbiome in Preterm Infants
The gut microbiome plays a significant role in balancing the inflammatory system in the immature gut. A breakdown in this balance with altered colonization of the microbiota in very low birth weight (VLBW) preterm infants is…
- Trial name
- NCT03422562
- Testing
- Florababy
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- Belal Alshaikh
Blastocystis Infections
Molecular Characterization of Blastocystis Isolates From Human by Restriction Fragment Length Polymorphism (RFLP) Analysis
Blastocystis is an anaerobic unicellular protozoal parasite infecting the gastrointestinal tract of humans and a wide range of animals.
- Trial name
- NCT05580393
- Testing
- RFLP analysis of SSU rRNA
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Appendicitis
Polymer Clips Versus Endoloops for Closure of the Appendiceal Stump During Emergency Laparoscopic Appendicectomy
The investigators propose a study to compare two methods of closing the stump of the appendix during an emergency excision of the appendix using a keyhole approach.
- Trial name
- PECAS (NCT02726152)
- Testing
- Polymer clips for closure of the appendiceal stump, Endoloops for closure of the appendiceal stump
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Health Service, United Kingdom
HIV Infections, Cryptosporidiosis
Nitazoxanide for the Treatment of Chronic Diarrhea in HIV Infected Children
Cryptosporidium parvum (C. parvum) is a parasite that can cause chronic diarrhea and is a significant problem for HIV infected children in developing countries. C. parvum infection can be treated with the drug nitazoxanide (NTZ).
- Trial name
- NCT00055107
- Testing
- Nitazoxanide
- Where
- 2 sites in South Africa, Thailand
- Volunteers
- 6 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Child Development, Growth
Health and Early Life Microbiota
The aim of this cohort is to identify environmental, lifestyle and genetic factors that modify the human intestinal microbiota development during the first years of life, and to identify early microbiota features that associate…
- Conditions
- Child Development, Growth, Allergy, Overweight
- Trial name
- HELMi (NCT03996304)
- Where
- Finland
- Volunteers
- 1,055 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
HIV Infections
Surveillance and Medical Help for HIV-infected Intravenous Drug Users in and Out of Prison
It is difficult to detect the intestinal protozoal infections among the HIV-infected persons or travelers diarrhea by using the traditional microscopy or staining methods.
- Trial name
- NCT00739258
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Appendicitis, Child
Conservative Treatment of Acute Appendicitis in Children
This is a feasibility study that will be performed at the Astrid Lindgren Children´s Hospital, Karolinska University Hospital, Stockholm, Sweden.
- Trial name
- CONSAPP Pilot (NCT01572558)
- Testing
- Appendectomy, Conservative, non-surgical treatment
- Where
- Sweden
- Volunteers
- 51 people
- Sponsor
- Karolinska University Hospital
Appendicitis
Importance of Peritoneal Free Fluid Cultures in Acute Appendicitis
The purpose of this study is to evaluate the frequency of positive free fluid cultures in both perforated and non-perforated appendicitis. In addition predictors of positive free fluid cultures will be analyzed.
- Trial name
- IFFSA (NCT01953289)
- Where
- Belgium
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Appendicitis, Surgery
The Effect of Kinesio Taping in Pediatric Surgery
This study was planned to determine the effect of kinesio taping (KT) applied to the abdominal area after surgery on pain and gas output in children aged 6-12 years who had open appendicitis surgery.
- Conditions
- Appendicitis, Surgery, Pain, Acute
- Trial name
- NCT06344897
- Testing
- Kinesio taping
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- KTO Karatay University
Children, Appendicitis
Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Children Undergoing Laparoscopic Appendicectomy
QL block has been recently described for chronic pain following abdominal hernia repair, and for postoperative analgesia following abdominal surgery as it leads to complete pain relief in the dermatomal area from (T6 - L1).
- Trial name
- NCT04031196
- Testing
- QLB, TAP block
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Perforated Appendicitis
Surgical Site Infection in Perforated Appendicitis After Peritoneal Lavage With Super-oxidised Solution
This study is to evaluate the effectiveness of peritoneal lavage with super-oxidised solution in reducing surgical site infection after open surgery for perforated appendicitis.
- Trial name
- PLaSSo (NCT04512196)
- Testing
- Superoxidized Water, Normal Saline
- Where
- Malaysia
- Volunteers
- 102 people
- Sponsor
- Hospital Queen Elizabeth, Malaysia
Angioimmunoblastic T-cell Lymphoma, B-cell Childhood Acute Lymphoblastic Leukemia
Oxaliplatin, Ifosfamide and Etoposide in Treating Young Patients With Recurrent or Refractory Solid Tumors or Lymphoma
This phase I trial is studying the side effects and best dose of oxaliplatin and etoposide in treating young patients with recurrent or refractory solid tumors or lymphomas.
- Conditions
- Angioimmunoblastic T-cell Lymphoma, B-cell Childhood Acute Lymphoblastic Leukemia, B-cell Chronic Lymphocytic Leukemia, Childhood Burkitt Lymphoma
- Trial name
- NCT00101205
- Testing
- oxaliplatin, etoposide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute (NCI)
Appendicitis
Open Appendectomy Versus Laparoscopic Appendectomy
1. Laparoscopic appendectomy may not be a superior procedure when compared with open appendectomy; 2. Various modifications in laparoscopic appendectomy procedure may reduce the technical diffuculty and overall costs.
- Trial name
- NCT01260064
- Testing
- Open appendectomy, Laparoscopic appendectomy with metal endoclips, Laparoscopic appendectomy with suture ligation
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Acute Appendicitis
A Trial on Laparoscopic Appendectomy Versus Single Port Appendectomy
The aim of this study is to compare patients who undergone single-port access laparoscopic appendectomy to those who underwent conventional three-port laparoscopic appendectomy (TPLA) in a prospective randomized trial
- Trial name
- NCT01348464
- Testing
- single port appendectomy, three port appendectomy
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Gachon University Gil Medical Center
Microbial Colonization
The Influence of Infant Feeding Type on Preterm Infant's Intestinal Microbiome
This study aims to examine the factors associated with preterm infant's intestinal microbiota depending on feeding type (breast milk or preterm formula)
- Trial name
- NCT04972214
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- CHA University
Dyspepsia Abdominal Burning Pain Diarrhea Dysentery
Concomitant Infection of Intestinal Parasites and Helicobacter Pylori
Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in…
- Trial name
- NCT05360940
- Testing
- H.pylori stool antigen rapid test and stool parasitological examination
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Clostridium Enterocolitis, Pseudomembranous Colitis
Association Between Response to Treatment of C. Diff Colitis and Anti-C.Diff Toxin Antibody
The purpose of this study is three fold: 1)To collect serum from patients with documented Clostridium difficile infection and test for the presence of antibody to C.
- Conditions
- Clostridium Enterocolitis, Pseudomembranous Colitis, Antibiotic-Associated Colitis
- Trial name
- NCT00304408
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Michael E. DeBakey VA Medical Center