Clinical trials: Intestines Cancer
Colorectal Cancer
Prognostic Value of Each Codon-specific KRAS Mutation in Colorectal Cancer
This retrospective study reviewed 3,144 patients who underwent surgery for colorectal cancer. This study was designed to comprehend the clinicopathological characteristics associated with individual codon-specific KRAS mutations…
- Trial name
- NCT05657210
- Testing
- Mutation
- Where
- South Korea
- Volunteers
- 2,203 people
- Sponsor
- Seoul National University Bundang Hospital
Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Acute Undifferentiated Leukemia
Fludarabine Phosphate and Total-Body Radiation Followed by Donor Peripheral Blood Stem Cell Transplant and Immunosuppression in Treating Patients With Hematologic Malignancies
This clinical trial studies fludarabine phosphate and total-body radiation followed by donor peripheral blood stem cell transplant and immunosuppression in treating patients with hematologic malignancies.
- Conditions
- Acute Myeloid Leukemia/Transient Myeloproliferative Disorder, Acute Undifferentiated Leukemia, Adult Acute Lymphoblastic Leukemia in Remission, Adult Acute Myeloid Leukemia in Remission
- Trial name
- NCT00014235
- Testing
- fludarabine phosphate, total-body irradiation, peripheral blood stem cell transplantation
- Where
- 11 sites in United States, Germany and 1 more
- Volunteers
- 160 people
- Sponsor
- Fred Hutchinson Cancer Center
Vitamin D on Tumor Response and Inflammatory Markers, Colo-rectal Cancer
Evaluation the of Role of Vitamin D Supplement on Tumor Response, Inflammation and Apoptosis in Patients With Stage II or III Colorectal Cancer Receiving Chemotherapy.
The aim of this work is to assess the of role of Vitamin D supplement on tumor response, inflammation and apoptosis in patients with stage II or III colorectal cancer receiving chemotherapy using BAX protein and Tumor necrosis…
- Trial name
- NCT07241247
- Testing
- Vitamin D
- Where
- Egypt
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Tanta University
Rectal Cancer, Neoplasm Metastasis
A Study of Preoperative Radiation Therapy and Capecitabine in Locally Advanced Rectal Cancer
The purpose of this trial is to study the efficacy of preoperative radiation therapy and capecitabine in locally advanced rectal cancer.
- Trial name
- NCT00122291
- Testing
- Capecitabine, Pelvic radiation
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Alberta Health services
Colorectal Cancer, Colorectal Neoplasms
Molecular Effects of Aspirin & Metformin on Colonic Epithelium
Bowel cancer, a significant problem in the United Kingdom (UK) with ~ 41,000 diagnoses and ~ 16,000 deaths annually, has a large preventable component (~54%).
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenoma
- Trial name
- NCT05158374
- Testing
- Aspirin tablet, Metformin, Aspirin and Metformin
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Edinburgh
Breast Cancer, Colorectal Cancer
Identification of Genes Associated With Cancer in Patients and Siblings Who Have Cancer
RATIONALE: Identification of genes that may be associated with developing certain types of cancer may someday provide important information about a person's risk of getting cancer.
- Conditions
- Breast Cancer, Colorectal Cancer, Lung Cancer, Prostate Cancer
- Trial name
- NCT00003329
- Testing
- gene mapping
- Where
- 32 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- Eastern Cooperative Oncology Group
Rectal Cancer, Colo-rectal Cancer
Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery
When a patient is diagnosed with a rectal (bowel) polyp or cancer, radiology doctors read MRI scans to describe how deeply the cancer invades into the bowel wall (this is the 'stage' of the cancer).
- Trial name
- PRESERVE (NCT04103372)
- Testing
- MRI scan, Radiologist training
- Where
- 23 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Colonic Neoplasms, Rectal Neoplasms
First-Line Bevacizumab and Chemotherapy in Metastatic Cancer of the Colon or Rectum - International Study
First-Line Bevacizumab and Chemotherapy in Metastatic Cancer of the Colon or Rectum
- Trial name
- NCT00537901
- Testing
- First-Line Bevacizumab and Chemotherapy, Bevacizumab
- Volunteers
- 100 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Colorectal Cancer
Curative Proton Beam Therapy for Patients With Liver Metastasis of Colorectal Cancer
Proton alone therapy is performed -> 5 times a week, 7200 cGy / 15 fractions for 3 weeks total
- Trial name
- NCT03577665
- Testing
- curative proton therapy
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- National Cancer Center, Korea
Colorectal Neoplasm
A LAparoscopic and TransAnal Total Mesorectal Excision (TME) for Rectal Cancer Trial
All patients planned for an anterior resection due to rectal cancer with a total mesorectal excision are included. This is a feasibility study, thus no randomization will be performed.
- Trial name
- LATA (NCT02324556)
- Where
- 2 sites in Sweden
- Volunteers
- 6 people
- Sponsor
- Sahlgrenska University Hospital
Constipation
The Bowel Research Collaborative Data Tracking System Implementation Study
The project's primary purpose is to establish a network of Hospice Palliative Care settings using a common and consistent method of assessing and documenting bowel functioning in order to be able to carry out future collaborative…
- Trial name
- NCT00728975
- Where
- Canada
- Volunteers
- 533 people
- Sponsor
- British Columbia Cancer Agency
Colorectal Neoplasms
A Phase II Study of 5-Fluorouracil Administered as a One Hour Infusion in Combination With Calcium Leucovorin and Interferon Alpha-2A in Advanced Colorectal Cancer
This protocol will evaluate the activity of 5-Fluorouracil (FUra) given as a 1 hour infusion in combination with leucovorin (LV) and interferon IFN alpha-2a in patients with advanced, measurable colorectal cancer.
- Trial name
- NCT00001428
- Testing
- 5-fluorouracil
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- National Cancer Institute (NCI)
Basal Cell Carcinoma of Skin, Site Unspecified, Epidermoid Carcinoma
Determining the Prevalence of Muir-Torre Syndrome in Patients With Lynch Syndrome
The main aim of this study is to determine the prevalence of Muir-Torre syndrome (MTS) in the population of patients with Lynch syndrome (LS) confirmed by genetic analysis.
- Conditions
- Basal Cell Carcinoma of Skin, Site Unspecified, Epidermoid Carcinoma, Lynch Syndrome, Muir-Torre Syndrome
- Trial name
- SMT-SL (NCT07201012)
- Testing
- Sampling of suspected skin lesions (in accordance with good care practices)., Constitution of a biobank
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Colorectal Neoplasms, Anastomotic Leak
Anastomotic Leakage and Enhanced Recovery Pathways After Colorectal Surgery
Prospective observational multicenter study on the influence of adherence to enhanced recovery pathways on early outcomes (anastomotic leakage, morbidity, mortality, readmission, reoperation rates and length of postoperative…
- Conditions
- Colorectal Neoplasms, Anastomotic Leak, Surgery--Complications
- Trial name
- iCral2 (NCT03771456)
- Testing
- Colorectal resections
- Where
- 41 sites in Italy
- Volunteers
- 1,748 people
- Sponsor
- Ospedale C & G Mazzoni
Colorectal Cancer, Colorectal Neoplasms
A Pilot Study to Explore the Role of Gut Flora in Colorectal Cancer
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding colorectal cancer.
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Carcinoma, Colorectal Adenocarcinoma
- Trial name
- NCT04148378
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Lymphoma
An Observational Study of Lymphoma in Patients With Rheumatoid Arthritis or Crohn's Disease.
The purpose of this study is to examine the association with EBV infection, monitor the occurrence of lymphoma and assess lymphoma risk in patients with rheumatoid arthritis and/or Crohns disease and you have taken infliximab.
- Trial name
- NCT00440817
- Testing
- No intervention
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- Centocor Ortho Biotech Services, L.L.C.
Colon Cancer
Definition of Surgical Technique of Lymphadenectomy and Complete Mesocolon Excision for Radical Right Colectomy: a Delphi Consensus
A Delphi consensus to define surgical steps of lymphadenectomy and complete mesocolic excision for radical right colectomy
- Trial name
- NCT05544474
- Testing
- Delphi questionnaire
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Advanced Solid Tumors, Metastatic Pancreatic Cancer
Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors
Background: Metastasis is the spread of cancer from one organ to a nonadjacent organ. It causes 90% of cancer deaths. No treatment specifically prevents or reduces metastasis. Researchers hope a new drug can help.
- Conditions
- Advanced Solid Tumors, Metastatic Pancreatic Cancer, Pediatric Solid Tumor, Advanced Breast Cancer
- Trial name
- NCT04222413
- Testing
- Metarrestin
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- National Cancer Institute (NCI)
Anastomotic Leakage
Anastomotic Leakage Following Laparoscopic Resection for Rectal Cancer
Anastomotic leak (AL) is a breakdown of a suture line in a surgical anastomosis with a subsequent leakage of the luminal content.
- Trial name
- NCT02718729
- Testing
- Laparoscopic resection for rectal cancer
- Where
- 2 sites in Egypt, Italy
- Volunteers
- 59 people
- Sponsor
- Mansoura University
Gastric Ulcer, Duodenal Ulcer
Cytokine Gene Polymorphisms in Gastric Diseases
Recently, cytokine polymorphisms are considered to play an important role in the pathogenesis of peptic ulcer and gastric cancer.
- Conditions
- Gastric Ulcer, Duodenal Ulcer, Gastric Cancer
- Trial name
- NCT00197470
- Testing
- IL-1, TNF-alpha, Il-10
- Where
- Japan
- Sponsor
- Hamamatsu University