Clinical trials: Intra-operative Blood Loss
Uterine Fibroids (Leiomyoma), Myomectomy
Bilateral Uterine Artery Occlusion During Laparoscopic Myomectomy
The current study is a multiple-arm, single blinded, and controlled randomized trial. It will be conducted in two gynecological endoscopy centers: • ElShatby University Hospital, a tertiary level hospital in Alexandria, Egypt.
- Conditions
- Uterine Fibroids (Leiomyoma), Myomectomy, Myomectomy; Surgical Blood Loss
- Trial name
- NCT07352761
- Testing
- Temporary clipping of uterine artery, Temporary occlusive suturing of uterine artery, Bipolar coagulation of uterine arteries
- Where
- 2 sites in Egypt
- Volunteers
- 60 people
- Sponsor
- Alexandria University
Plasma Volume Substitution (Hypovolemia) Including Massive Hemorrhage
Study to Obtain Volume Effect and Safety Data on 6 % Hydroxyethyl Starch 130/0.4 in Pediatric and Adult Patients Undergoing Major Elective Surgery
The study shall evaluate the volume effect and safety of 6 % hydroxyethyl starch 130/0.4 for restoration and maintenance of hemodynamics during the investigational period in patients undergoing major elective surgery.
- Trial name
- NCT01127477
- Testing
- 1: Hydroxyethyl starch 130/0.4, 6 %
- Where
- 4 sites in Japan
- Volunteers
- 20 people
- Sponsor
- Fresenius Kabi Japan
Peri-operative Hemorrhage or Hematoma, Surgery
Preventive EXACYL® on Perioperative Bleeding During Orthognathism of Maxillary Surgery
Prospective, randomized, double-blind, placebo-controlled, mono center, Phase III trial to compare EXACYL in preventive with placebo on perioperatory bleeding in orthognathism surgery.
- Conditions
- Peri-operative Hemorrhage or Hematoma, Surgery, Retrognathism
- Trial name
- LEFORTEXACYL (NCT02702128)
- Testing
- Tranexamic Acid, saline solution
- Where
- France
- Volunteers
- 157 people
- Sponsor
- University Hospital, Lille
Anesthesia Complication, Surgical Blood Loss
Cerebral Oxygenation, Different Measurement Points and Their Correlation in Pediatric Population
Children who undergo surgery routinely for surgery that risk high levels of circulatory changes (eg heart surgery) is currently used routinely monitoring as regional oxygenation technology of the brain (NIRS).
- Trial name
- NCT03136952
- Testing
- NIRS frontal and occipital
- Where
- Sweden
- Volunteers
- 17 people
- Sponsor
- Göteborg University
Intra-operative Bleeding
Oxidized Cellulose hEmostAsis evaluatioN
The purpose of this study is to evaluate the safety and effectiveness of Traumastem to help stop bleeding in participants undergoing open cardiac, intra-abdominal (including retroperitoneal) and pelvic surgery as compared to…
- Trial name
- OCEAN (NCT01637025)
- Testing
- Oxidized cellulose strip, Oxidized regenerated cellulose strip
- Where
- 24 sites in Czechia, Germany and 2 more
- Volunteers
- 111 people
- Sponsor
- Baxter Healthcare Corporation
Laparoscopic Pancreaticoduodenectomy
Establishment and Application of an Artificial Intelligence Algorithm for Automatic Identification of Intraoperative Bleeding During Laparoscopic Pancreaticoduodenectomy
Surgeons will label surgical videos of laparoscopic pancreaticoduodenectomy with bleeding information from multicenter. The labeled surgical video will be used as training material to train the algorithmic model so as to build an…
- Trial name
- NCT06172062
- Testing
- laparoscopic pancreaticoduodenectomy
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xinrui Zhu，MD
Osteoarthritis, Hip, Joint Deformities, Acquired
Efficacy of Aquamantys for Reducing Transfusions With Anterior Supine Intermuscular Approach Total Hip Arthroplasty
The purpose of this study is to establish whether or not there is a clinical advantage to the use of Aquamantys® System from Medtronic Advanced Energy (formerly Salient Surgical Technologies) in patients undergoing primary total…
- Conditions
- Osteoarthritis, Hip, Joint Deformities, Acquired, Hip Dislocation, Congenital, Osteonecrosis
- Trial name
- Aquamantys (NCT01583465)
- Testing
- Aquamantys, standard electrocautery (Bovie)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Joint Implant Surgeons, Inc.
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Blood Loss, Surgical
Evaluation of Fibrin Sealant 2 in Retroperitoneal or Intra-Abdominal Surgery
A comparison of fibrin sealant 2 versus Surgicel® as an addition to standard surgical practice in stopping mild to moderate soft tissue bleeding during retroperitoneal or intra-abdominal surgery.
- Trial name
- NCT00307515
- Testing
- Fibrin Sealant 2 (FS2), Oxidized Regenerated Cellulose (Surgicel)
- Where
- 16 sites in United States
- Volunteers
- 135 people
- Sponsor
- Ethicon, Inc.
Shoulder Arthritis, Blood Loss, Surgical
Effect of TXA on Blood Loss in Reverse Total Shoulder Arthroplasty
Tranexamic acid (TXA) is a synthetic anti-fibrinolytic agent that has been well studied and routinely used for hip and knee arthroplasty.
- Conditions
- Shoulder Arthritis, Blood Loss, Surgical, Tranexamic Acid Adverse Reaction
- Trial name
- NCT06638749
- Testing
- Tranexamic Acid, Normal Saline
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Hypotension During Surgery, Blood Loss, Surgical
Reducing Hypotensive Anesthesia Use With TXA During Orthognathic Surgery
This prospective study will analyze the need for deliberate hypotensive anesthesia (DHA) during orthognathic surgery when tranexamic acid (TXA) is administered.
- Trial name
- NCT05474027
- Testing
- Avoidance of Deliberate Hypotensive Anesthesia, TRANEXAMIC ACID 1 G in 10 mL INTRAVENOUS INJECTION, SOLUTION
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bone Tumor
The Epidural Anesthesia on the Intra-operative and Post-operative Amount of Bleeding Post Lower Limb Salvage Surgery
Epidural anesthesia is a very useful tool in lower limb salvage surgery, which helps pain control intra and more importantly post-operative pain.
- Trial name
- NCT01679691
- Testing
- epidural anesthesia
- Where
- Egypt
- Sponsor
- Children's Cancer Hospital Egypt 57357
Cesarean Scar Pregnancy
MRI in Predicting Intraoperative Massive Hemorrhage for Cesarean Scar Pregnancy
MRI features and clinical characteristics to predict massive hemorrhage during hysteroscopic treatment of CSP, and to aid the choice of treatment.
- Trial name
- NCT04955028
- Volunteers
- 300 people
- Sponsor
- Peking University Third Hospital
Cleft Palate, Hemorrhage
Acid Tranexamic Effectiveness in Reducing the Intraoperative Bleeding in Palatoplasty
Randomized study evaluating the role of tranexamic acid in reducing intraoperative bleeding in palatoplasty.
- Trial name
- NCT02422056
- Testing
- Tranexamic Acid, Saline
- Volunteers
- 66 people
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Myomectomy
Tranexamic Acid Versus Vaginal Misoprostol in Abdominal Myomectomy
the aim of the present study is to evaluate safety and efficacy of tranexamic acid versus vaginal misoprostol in reducing intraoperative blood loss during abdominal myomectomy
- Trial name
- NCT04358965
- Testing
- intravenous tranexamic acid, vaginal misoprostol
- Volunteers
- 162 people
- Sponsor
- Cairo University
Surgical Blood Loss, Surgical Hemorrhage
TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss
The research team proposes a prospective, observational study to better understand how TEG can be useful in guiding clinical practice in the Main OR for subject's undergoing high transfusion risk surgeries.
- Conditions
- Surgical Blood Loss, Surgical Hemorrhage, Post Operative Hemorrhage
- Trial name
- NCT05379530
- Testing
- Thromboelastography (TEG), Anesthesia Provider Survey
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Hemorrhage, Surgical, Tonsillar Bleeding
TEAPOT Study Multisite
After a child has their tonsils removed, sometimes they might bleed which can be a problem. There is a special mist medicine called nebulized tranexamic acid (TXA) that might help stop the bleeding without having to touch the…
- Trial name
- TEAPOT (NCT07565753)
- Testing
- Tranexamic Acid Injectable Product, Normal Saline
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Knee Arthroplasty, Total
Low Dose Peri- Operative Intra Venous Teranexamic Acid Reduces Blood Loss After Total Knee Arthroplasty: A Double Blind Randomized Placebo Controlled Clinical Trial
Total Knee Arthroplasty (TKA) is a common orthopedic surgery usually leads to Bleeding. The null hypothesis of this study was that TA has no effect on post surgical bleeding in patients undergoes TKA.
- Trial name
- NCT02327117
- Testing
- Tranexamic Acid, Normal saline
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Isfahan University of Medical Sciences
Surgery, Blood Loss, Surgical
Investigation of the Transfusion Practices in Surgical Patients in Turkey
The aim of this study is to describe the transfusion practices in patients undergoing major surgery in Turkey. The transfusion rates of red blood cells (RBC), fresh frozen plasma (FFP) and platelets; the transfusion predictors…
- Conditions
- Surgery, Blood Loss, Surgical, Blood Loss Anemia, Blood Transfusion
- Trial name
- CeKATU (NCT03468738)
- Testing
- Blood transfusion
- Where
- 61 sites in Turkey (Türkiye)
- Volunteers
- 6,481 people
- Sponsor
- Diskapi Teaching and Research Hospital
Coagulation Protein Disorders, Blood Loss, Surgical
Observational Study of Prophylaxis and Treatment of Acute Perioperative Bleeding With Beriplex® P/N (Probe Study)
Beriplex® P/N is made from human plasma (the liquid part of the blood) and contains the coagulation factors II, VII, IX and X which are important for blood clotting (coagulation).
- Conditions
- Coagulation Protein Disorders, Blood Loss, Surgical, Perioperative Care
- Trial name
- NCT01053169
- Testing
- Beriplex® P/N, Fresh Frozen Plasma (FFP) and Beriplex® P/N, Fresh Frozen Plasma
- Where
- 6 sites in United Kingdom
- Volunteers
- 445 people
- Sponsor
- CSL Behring