Clinical trials: Intracerebral Hemorrhage
Head Injury, Intracerebral Hemorrhage
The Prediction of Intracranial Pressure and Clinical Outcome by Transcranial Doppler in Neurocritical Patients
The purpose of this study is to use transcranial Doppler (TCD) to predict intracranial pressure (ICP) and clinical outcome of neurocritical patients.
- Conditions
- Head Injury, Intracerebral Hemorrhage, Ischemic Stroke, Subarachnoid Hemorrhage
- Trial name
- NCT00886054
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Intracerebral Hemorrhage
Retrospective Study of Intracerebral Hemorrhage Patients in Hospital Parc Taulí
This is a retrospective observational study to investigate the clinical, analytical and neuroimaging data generated during routine clinical management of intracerebral hemorrhage.
- Trial name
- NCT04877405
- Testing
- No intervention
- Where
- Spain
- Volunteers
- 137 people
- Sponsor
- Universitat Autonoma de Barcelona
Cerebral Hemorrhage
Retrospective Study on the Direction of Artificial Intelligence in Identifying Cranial Trauma CT Imaging
The goal of this observational retrospective study is to evaluate artificial intelligences (AI)'s proficiency in identifying and annotating brain bleeds in computed tomography (CT) images.
- Trial name
- NCT06230419
- Where
- China
- Volunteers
- 208 people
- Sponsor
- RenJi Hospital
Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases
Cerebral Arteriovenous Malformation With Aneurysm: Epidemiology, Clinical Features, and Prognosis
The study is a multicenter, prospective cohort study designed to assess the natural history, clinical safety and efficacy of various treatment strategies in patients with cerebral arteriovenous malformations (AVMs) and…
- Conditions
- Cerebral Arteriovenous Malformation, Intracranial Arterial Diseases, Intra Cerebral Hemorrhage, Intracranial Aneurysm
- Trial name
- NCT07353736
- Where
- China
- Volunteers
- 630 people
- Sponsor
- Duan Chuanzhi
Intracerebral Hemorrhage, CAA - Cerebral Amyloid Angiopathy
MRI-markers to Monitor Small Vessel Disease Dynamics in the Prognosis of Small Vessel Disease-associated, Cerebrovascular Events
This is a nested cohort study in the PRO-SVD cohort. Small vessel disease is a chronic disease and is thought to progress over time.
- Conditions
- Intracerebral Hemorrhage, CAA - Cerebral Amyloid Angiopathy, Cerebral Small Vessel Diseases
- Trial name
- MRI-PRO-SVD (NCT05773235)
- Testing
- Combined 3- and 7 Tesla-MRI
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Hereditary Hemorrhagic Telangiectasia
Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia
This study is one of the three projects of an NIH Rare Disease Clinical Research Consortium. A "consortium" is a group of centres sharing information and resources to perform research.
- Trial name
- BVMC6203 (NCT01158807)
- Where
- 19 sites in United States, Canada and 1 more
- Volunteers
- 2,272 people
- Sponsor
- Unity Health Toronto
Preterm Birth, Coagulation Protein Disorders
Stratifying Risk for Intracerebral Haemorrhage
This study aims to investigates the role of gestational age on the prevalence of coagulation factors and components of the complement system in preterm- (≤32+0 weeks) and term neonates (≥37+0 weeks) and their role for the…
- Conditions
- Preterm Birth, Coagulation Protein Disorders, Coagulation Disorder Neonatal
- Trial name
- NEW_STRATEGI (NCT04140812)
- Testing
- mass spectrometry (LC-MS/MS)
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Traumatic Brain Injury, Cerebral Infarction
Characteristics of Blood- Brain Barrier Permeability in Neurological Patients
The main goal of the present study is to challenge the hypothesis that blood- brain barrier disruption following brain injury increases the risk for long-term disability, development of brain dysfunction, epileptic seizures and…
- Conditions
- Traumatic Brain Injury, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00419874
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Intracerebral Hemorrhage
The REgistry Study on Multimodality trEAtment foR Cerebral Hemorrhage
The REgistry Study on multimodality trEAtment foR Cerebral Hemorrhage (RESEARCH) aims to address these challenges by establishing a comprehensive national registry.
- Trial name
- RESEARCH (NCT06629532)
- Testing
- medical management, surgical interventions, and rehabilitative strategies
- Volunteers
- 100,000 people
- Sponsor
- Tao Liu
Subarachnoid Hemorrhage, Pneumonia, Bacterial
Influence of Pneumonia on Delayed Cerebral Ischemia After Subarachnoid Hemorrhage . SAH-CIP (SubArrachnoid Hemorrhage - Cerebral Infarction Pneumonia)
Prognosis of subarachnoid hemorrhage (SAH) is scarce, indeed almost half patients die or become severely disable after SAH. Outcome is related to the severity of the initial bleeding and delayed cerebral infarction (DCI).
- Trial name
- SAH-CIP (NCT05094349)
- Where
- France
- Volunteers
- 224 people
- Sponsor
- University Hospital, Brest
Traumatic Brain Injury, Subarachnoid Hemorrhage
Near Infrared Spectroscopy (NIRS) as Transfusion Indicator in Neurocritical Patients
Neurocritical ill patients are frequently transfused. Red blood cell transfusion (RBCT) in these patients has been associated with deleterious effects, including higher rates of nosocomial infections, multi-organ failure, and…
- Conditions
- Traumatic Brain Injury, Subarachnoid Hemorrhage, Intracerebral Hemorrhage
- Trial name
- NCT00566709
- Testing
- Red blood cells transfusion
- Where
- Spain
- Volunteers
- 102 people
- Sponsor
- Hospitales Universitarios Virgen del Rocío
Premature Birth, Extremely Low Birth Weight
DCS Study in Extremely Premature Newborns
The researchers are attempting to improve the cerebral monitoring of extremely low gestational age (ELGA) infants, such that in the future, real-time monitoring will be possible, to aid clinicians in management of these infants.
- Conditions
- Premature Birth, Extremely Low Birth Weight, Infant, Small for Gestational Age, Intracerebral Hemorrhage
- Trial name
- NCT04367181
- Testing
- Diffuse Correlation Spectroscopy (DCS), Amplitude Integrated Electroencephalography (aEEG)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Maria Angela Franceschini
Consciousness Disorders, Persistent Vegetative State
Multimodal Assessment and Prognosis in Disorders of Consciousness After Severe Brain Injury (CyDoC-MAP)
After a severe brain injury some patients survive but cannot communicate, and deciding early which of them are likely to recover consciousness remains one of the hardest problems in neurocritical care.
- Conditions
- Consciousness Disorders, Persistent Vegetative State, Unresponsive Wakefulness Syndrome, Minimally Conscious State
- Trial name
- CyDoC-MAP (NCT07736820)
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- Nicosia General Hospital
Infant, Very Low Birth Weight, Infant, Premature, Diseases
Regulation of Cerebral Blood Flow in Very Low Birth Weight Infants
Advances in newborn intensive care have lead to dramatic improvements in survival for the most premature infants-often weighing 1 pound at birth.
- Conditions
- Infant, Very Low Birth Weight, Infant, Premature, Diseases, Cerebral Hemorrhage
- Trial name
- NCT00579943
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Arkansas
Infant, Newborn, Infant, Low Birth Weight
Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage
This large randomized trial tested whether phenobarbital given to a pregnant woman about to deliver a premature infant would prevent brain injuries in their newborns.
- Conditions
- Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature
- Trial name
- Phenobarbital (NCT00009620)
- Testing
- Phenobarbital, Saline
- Where
- 11 sites in United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- NICHD Neonatal Research Network
Acute Brain Injury
The NEUROlogically-impaired Extubation Timing Trial
This randomized controlled trial will enrol patients with acute severe brain injury who pass a spontaneous breathing trial but have decreased level of consciousness. It will directly compare (1) prompt extubation vs.
- Trial name
- NEURO-ETT (NCT02920580)
- Testing
- Extubation, Usual Care
- Where
- 13 sites in Canada
- Volunteers
- 27 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage
Methods of Etiological Diagnosis of Cerebral Amyloid Angiopathy
The purpose of this study is to 1. Early identify patients based on clinical manifestation, imaging, gene and histology, explore diagnostic tools 2. get gene repertoire of Chinese 3.
- Trial name
- NCT02361411
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Peking University Third Hospital
Intracerebral Hemorrhage, Outcome
Prognosis in Intracerebral Hemorrhage. The ICHCat Score in Primary Care.
The clinical evidence shows that patients with a first episode of intracerebral hemorrhage (ICH) are increasingly old and with greater comorbidity with a recognized impact over mortality.
- Conditions
- Intracerebral Hemorrhage, Outcome, Survival, Primary Care
- Trial name
- ICHCat (NCT03247049)
- Volunteers
- 262 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Stroke, Acute
National Cerebral and Cardiovascular Center (NCVC) Stroke Registry
A single-center registry of patients with acute ischemic stroke, intracerebral hemorrhage, and transient ischemic attack (TIA) who are emergently managed in the stroke care unit in the National Cerebral and Cardiovascular Center…
- Trial name
- NCT02251665
- Testing
- No intervention
- Where
- Japan
- Volunteers
- 5,374 people
- Sponsor
- National Cerebral and Cardiovascular Center, Japan
Moyamoya Disease, Moyamoya Syndrome
Development and Validation of Risk Prediction Models for Stroke and Cognitive Impairment in Moyamoya Disease and Moyamoya Syndrome
This multicenter prospective observational cohort study aims to develop and validate individualized risk prediction models for stroke and cognitive decline in patients with moyamoya disease or moyamoya syndrome by integrating…
- Trial name
- NCT07894107
- Where
- 13 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Tiantan Hospital