Clinical trials: Intracranial Aneurysms
Aneurysm, Vasospasm
Balloon Prophylaxis of Aneurysmal Vasospasm
The purpose of this study is to determine if early transluminal ballooning of the major cerebral arteries prevents severe vasospasm and improves neurological outcome in patients with Fisher Grade III aneurysmal subarachnoid…
- Trial name
- NCT00282893
- Testing
- transluminal ballooning, currently existing therapies for the treatment of vasospasm
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 170 people
- Sponsor
- University of California, Davis
Epileptic Seizure, Intracranial Tumor
Our Anesthesia Experience During MRI Scan
In this study we aim to investigate the relationship between our anesthesia practice and post procedure complications after MRI scanning with sedation. This is a retrospective, single center observational study.
- Conditions
- Epileptic Seizure, Intracranial Tumor, Intracranial Hypertension, Intracranial Aneurysm
- Trial name
- NCT03123302
- Where
- Turkey (Türkiye)
- Volunteers
- 977 people
- Sponsor
- Akdeniz University
Cardiac Rhythm Disorders, Urological Disorders
Product Surveillance Registry
The purpose of the Registry is to provide continuing evaluation and periodic reporting of safety and effectiveness of Medtronic market-released products.
- Conditions
- Cardiac Rhythm Disorders, Urological Disorders, Neurological Disorders, Cardiovascular Disorders
- Trial name
- PSR (NCT01524276)
- Where
- 402 sites in United States, Argentina and 39 more
- Volunteers
- 100,000 people
- Sponsor
- Medtronic
Aneurysm, Aneurysm, Brain
Setting Benchmarks for Microsurgical Clipping of Unruptured Intracranial Aneurysms
To conduct a retrospective multicenter cohort study to define benchmark values for best achievable outcomes following microsurgical clipping of unruptured intracranial aneurysms (UIA).
- Conditions
- Aneurysm, Aneurysm, Brain, Aneurysm Cerebral, Aneurysm of Cerebral Artery
- Trial name
- NCT05029947
- Testing
- Microsurgical Clipping of Unruptured Intracranial Aneurysm
- Where
- Germany
- Volunteers
- 3,000 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Intracranial Aneurysms
Treatment of Cranial Internal Carotid Artery Aneurysm With Willis Covered Stent and Coil Embolization
Intracranial aneurysm treatment with coil embolization is associated with relatively low complete occlusion and high recanalization rates.
- Trial name
- NCT01029938
- Testing
- Covered stent, Coil
- Where
- 2 sites in China
- Volunteers
- 85 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Intracranial Aneurysm
Cascade Clinical Data Collection Protocol
This study is a multi-center, single arm, open label, retrospective and prospective clinical data collection of CascadeTM, Non-Occlusive Remodeling Net, in adults with intracranial aneurysms, demonstrating the effectiveness and…
- Trial name
- NCT04760925
- Testing
- CascadeTM, Non-Occlusive Remodeling Net
- Where
- 7 sites in Bulgaria, Germany and 3 more
- Volunteers
- 112 people
- Sponsor
- Perflow Medical
Saccular and Fusiform Aneurysms, Pseudoaneurysm
Targeting Real World Usage In Stroke Treatment
TRUST Registry is an observational, prospective, long-term, post-market surveillance registry of subjects treated with WallabyPhenox flow modulation devices, stent systems, bifurcation aneurysm implants including their HPC…
- Conditions
- Saccular and Fusiform Aneurysms, Pseudoaneurysm, Vascular Dissection, Perforation
- Trial name
- TRUST (NCT07474935)
- Testing
- Aneurysm Treatment with a Neurovascular Flow Diverter, Dissection Treatment with a Neurovascular Flow Diverter, Perforation Treatment with a Neurovascular Flow Diverter
- Where
- 13 sites in France, Germany and 3 more
- Volunteers
- 5,000 people
- Sponsor
- Phenox GmbH
Vein of Galen Malformation
Vein of Galen Aneurysm
1. Foundations of the clinical research project: Vein of Galen vascular malformations are a group of rare cerebral vascular malformations with complex anatomy and severe clinical consequences.
- Trial name
- NCT06595264
- Testing
- embolization therapy
- Where
- Belgium
- Volunteers
- 19 people
- Sponsor
- Erasme University Hospital
Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage
Remote Ischemic Preconditioning in Subarachnoid Hemorrhage
Rupture of brain aneurysms is a common cause of death and disability, accounting for as many as 10% of stroke cases in the United States.
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal, Subarachnoid Hemorrhage, Cerebral Vasospasm, Intracranial Aneurysm
- Trial name
- RIPC-SAH (NCT01158508)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Los Angeles
Aneurysm Cerebral, AVM
This Three-year Observational Study Involves Patients of All Ages Undergoing Endovascular Treatment for Various Cerebral or Spinal Vascular Conditions. It Aims to Assess Pre- and Post-operative Clinical Conditions, Report Complications, and Identify Preoperative Indicators of Treatment Outcomes. Pat
This three-year observational study involves patients of all ages undergoing endovascular treatment for various cerebral or spinal vascular conditions.
- Conditions
- Aneurysm Cerebral, AVM, DAFV, ESDC
- Trial name
- ONIRIC (NCT06805721)
- Where
- Italy
- Volunteers
- 1,000 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease
Evaluating a Wireless NIRS Device in the Neonatal Intensive Care Unit
The wireless NIRS sensor will be placed on the participant's forehead, directly underneath the INVOS wired sensor. The wireless NIRS sensor will remain in place for 4 consecutive hours, over 2 consecutive days.
- Conditions
- Hypoxic-Ischemic Encephalopathy, Congenital Heart Disease, Stroke Hemorrhagic, Aneurysm Cerebral
- Trial name
- NCT07732244
- Testing
- Wireless NIRS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Intracranial Aneurysms, Peripheral Aneurysms
Study of the Penumbra Coil 400 System to Treat Aneurysm
This is a prospective, multi-center study of patients with intracranial or peripheral aneurysms who are treated by the PC 400 System.
- Trial name
- ACE (NCT01465841)
- Testing
- PC 400 coils (Penumbra )
- Where
- 6 sites in United States
- Volunteers
- 517 people
- Sponsor
- Penumbra Inc.
Cerebral Arterial Aneurysm
Role of Propofol Postconditioning on Oxidative Stress and Cognitive Function
The purpose of this study was to evaluate differences between propofol postconditioning and sevoflurane anesthesia in the intracranial aneurysm surgery about antioxidant effect.
- Trial name
- NCT02691416
- Testing
- propofol postconditioning, sevoflurane
- Volunteers
- 60 people
- Sponsor
- The Third Central Clinical College of Tianjin Medical University
Intracranial Aneurysm
A Study on a Multidimensional Prediction Model for Rupture Risk of Unruptured Intracranial Aneurysms
This is a registry study on a multidimensional prediction model for rupture risk of unruptured intracranial aneurysms in China.
- Trial name
- CIAP-2 (NCT03133624)
- Where
- 12 sites in China
- Volunteers
- 500 people
- Sponsor
- Beijing Neurosurgical Institute
Intracranial Aneurysm
Tubridge Flow Diverter Study For Intracranial Aneurysms
The scope of this trial is the collection and analysis of the important safety outcomes in the real world, related to the use of the Tubridge flow diverter in the treatment of intracranial aneurysms.
- Trial name
- TRACE-IA (NCT05646108)
- Testing
- Endovascular treatment
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- MicroPort NeuroTech Co., Ltd.
Unruptured Cerebral Aneurysm, Treatment Strategy
New Therapeutic System of Unruptured Intracranial Aneurysms Based on Big Data From Chinese Population
This is a prospective, multicenter, observational study, aiming at comparing the Safety and effectiveness among the different surgical treatment of unruptured intracranial aneurysms in China, so as to improve the diagnosis and…
- Trial name
- NATIONAL-1 (NCT03153865)
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Intracranial Aneurysm
Safety and Performance of the Neuroform Atlas™ Stent System
The objective of this retrospective study is to describe in real-life settings the clinical practice, utilization and the treated population outcomes at 1-year (12-16 months) follow-up at selected, representative centers in…
- Trial name
- ATLAS-FR (NCT04162483)
- Testing
- Neuroform Atlas Stent System
- Where
- France
- Volunteers
- 310 people
- Sponsor
- Stryker Neurovascular
Intracranial Aneurysms
CARE: A Prospective Multicenter Case Study to Assess Radiation Exposure in Patients Treated With the Penumbra Coil 400
The primary objective of this study is to gather data on the radiation exposure in patients treated with the Penumbra Coil 400™ System (PC 400) or conventional coils per their respective indications for use.This is a multicenter…
- Trial name
- CARE (NCT02122133)
- Testing
- PC 400
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- Penumbra Inc.
Cardiac Diseases, Muscular Weakness
Biomarker for Pompe Disease (BioPompe)
Development of a new MS-based biomarker for the early and sensitive diagnosis of Pompe disease from blood (plasma)
- Conditions
- Cardiac Diseases, Muscular Weakness, Hepato-splenomegaly, Lung Disease
- Trial name
- BioPompe (NCT01457443)
- Where
- 4 sites in Germany, India and 1 more
- Sponsor
- CENTOGENE GmbH Rostock
Subarachnoid Hemorrhage, Brain Ischemia
Dapsone Use in Patients With Aneurysmal Subarachnoid Hemorrhage.
Dapsone is a drug that has been used clinically for several decades due to its anti-infective effect, making it widely available. Its neuroprotective effects have been found through its glutamate receptors antagonistic effect.
- Conditions
- Subarachnoid Hemorrhage, Brain Ischemia, Subarachnoid Hemorrhage, Aneurysmal, Aneurysmal Subarachnoid Hemorrhage
- Trial name
- NCT05131295
- Testing
- Dapsone, Aluminum Hydroxide Gel
- Where
- Mexico
- Volunteers
- 49 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez