Clinical trials: Intraoperative
Anesthesia, Emergence Delirium
The Effect of Anesthesia Depth Monitoring on Emergence Delirium in Pediatrics
Some changes in the patient's cognitive state are observed during the recovery period from general anesthesia. This period of behavioral dysregulation has been called emergence agitation (EA) and emergence delirium (ED).
- Conditions
- Anesthesia, Emergence Delirium, Anesthesia Awareness, Behavior Child Problems
- Trial name
- NCT06323616
- Testing
- MAC adjustment to PSI between 25 and 50
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Istanbul University
Intraoperative Hypotension, General Anesthesia
Deep Learning Models for Prediction of Intraoperative Hypotension Using Non-invasive Parameters
The investigators aimed to investigate the deep learning model to predict intraoperative hypotension using non-invasive monitoring parameters.
- Trial name
- NCT05762237
- Where
- South Korea
- Volunteers
- 5,175 people
- Sponsor
- Samsung Medical Center
Patients Undergoing External Dacrocystorhinostomy Operations, Assess Decreased Anesthetic Requirements Intraoperative
Dexmedetomidine an Effective Drug in Reducing Anesthetic Requirements in External Dacrocystorhinostomy (DCR) Patients
Assessing the intra and postoperative hemodynamic stability in patients undergoing external dacrocystorhinostomy under general anesthesia using Dexmedetomidine as a preoperative sedation compared to traditional technique with…
- Trial name
- DCR (NCT06808295)
- Testing
- Dexmedetomidine Hydrochloride
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
The Frequency of Anesthesia-related Critical Events, Anesthesia-related Intraoperative Critical Events
Anesthesia-Related Peroperative Critical Events
Peroperative anesthesia-related critical events (CE) lead to adverse health outcomes in patients. To minimize recurrence of these outcomes, identifying problems causing CEs and obtaining information about their frequency and…
- Conditions
- The Frequency of Anesthesia-related Critical Events, Anesthesia-related Intraoperative Critical Events, Anesthesia-related Postoperative Critical Events
- Trial name
- NCT06426940
- Testing
- anesthesia-related critical events
- Where
- Turkey (Türkiye)
- Volunteers
- 1,904 people
- Sponsor
- Gamze Küçükosman
Anesthesia, Neuromuscular Blockade
Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizing Muscle Relaxants
Although tonsillectomy is one of the most commonly performed surgeries, a review of literature reveals no articles dealing with the study of intraoperative blood loss in tonsillectomy and adenotonsillectomy according to the use…
- Conditions
- Anesthesia, Neuromuscular Blockade, Intraoperative Bleeding, Intraoperative Blood Loss
- Trial name
- NCT06399445
- Testing
- conventional cold tonsillectomy and curettage adenoidectomy, Rocuronium Bromide
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital of Split
Intraoperative Cardiac Arrest
Cardiopulmonary Resuscitation in Operating Room
In the last ten years patient safety during routine surgical interventions has increased; however as there is an increase in the number of specialized surgical interventions and high risk patients like elderly and emergency…
- Trial name
- CPR (NCT02884271)
- Testing
- cardiopulmonary resuscitation
- Where
- Turkey (Türkiye)
- Volunteers
- 7 people
- Sponsor
- Dokuz Eylul University
Hypotension, Neonatal Hypotension
Appropriate Dosage of Vasopressor in Neonates and Infants
In this study, the investigators will evaluate cerebral blood flow before and after drug infusion using ultrasound to suggest blood pressure criteria and dosage of ephedrine, a vasopressor, to maintain adequate cerebral blood…
- Conditions
- Hypotension, Neonatal Hypotension, Intraoperative Complications
- Trial name
- NCT06257316
- Testing
- EPHEDrine Hydrochloride 5 mg/ml
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Anesthesia, Monitoring, Intraoperative
Registry Construction of Intraoperative Vital Signs and Clinical Information in Surgical Patients
Monitoring data during anesthesia of surgical patient in the operation room will be collected and stored into the registry automatically. Patients' information and preoperative assessment from medical records will be included.
- Trial name
- NCT02914444
- Where
- South Korea
- Volunteers
- 200,000 people
- Sponsor
- Seoul National University Hospital
Scoliosis, Spinal Deformity
Bilateral Bi-level Erector Spine Plane Block as a Component of General Anesthesia in Surgical Correction of Spinal Deformations
Improving the anesthesiology management for surgical correction of spinal deformations with introducing the diagnostic methods and treatment strategy of acute pain, preventing the evolution of chronic pain.
- Conditions
- Scoliosis, Spinal Deformity, Acute Pain, Chronic Pain
- Trial name
- BBESPB (NCT04697498)
- Testing
- Bilateral bi-level Erector spine plane block, General anaesthesia
- Where
- Ukraine
- Volunteers
- 150 people
- Sponsor
- Lviv National Medical University
Intraoperative Complications
Ultrasonographic Assessment of Lung Recruitment Maneuvers in Children Undergoing Lengthy Microsurgery Operations
The aim of this study will be to explore the clinical value of ultrasonic monitoring in the diagnosis of anesthesia-induced atelectasis, the assessment of the effects of lung recruitment, the best positive end-expiratory pressure…
- Trial name
- RM (NCT03557905)
- Testing
- RM 0.5, RM 0.3
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Assiut University
Anesthesia Awareness
The Depth of Paediatric Anaesthesia: Observational Trial
Perioperative measurement of the Depth of anaesthesia is currently recommended part of daily anaesthesia good clinical practice. The optimal depth of anaesthesia measured by Bispectral index could be between 40-60.
- Trial name
- ANAPED (NCT05193747)
- Testing
- Anesthesia depth monitoring
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Brno University Hospital
Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
Impact of Intraoperative Spraying methylene blue In thyroidectomy
- Trial name
- methylene (NCT05367869)
- Testing
- Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Qena Oncology Center
Pain, Monitoring, Intraoperative
Evaluation of the Pupil Dilation Reflex in Response to Noxious Stimulation in Anaesthetized Children. A Proof of Concept Trial
After conduction a pilot study, pupillary dilation reflex (PDR) is measured in response to nociceptive stimulation perioperatively in infants, children and adolescents.
- Trial name
- Pain@OR-kids (NCT03449732)
- Testing
- PDR measurement
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine
Enhanced Perioperative Care for the Prevention of Colorectal Anastomotic Leakage
This multicenter open-label trial is designed to evaluate if the implementation of an enhanced peri-operative care protocol results in an optimal intraoperative condition of the patient and in a decrease in incidence of…
- Conditions
- Anastomotic Leak Small Intestine, Anastomotic Leak Large Intestine, Anastomotic Leak Rectum, Intraoperative Awareness
- Trial name
- DOUBLE CHECK (NCT05250882)
- Testing
- Enhanced perioperative care protocol
- Where
- 9 sites in Belgium, Netherlands
- Volunteers
- 1,600 people
- Sponsor
- Amsterdam UMC, location VUmc
Anesthesia, Anesthesia Awareness
Pediatric Validation of CONOX Monitor During Surgery
Pediatric Validation of CONOX Monitoring device (qCON and qNOX indices) for anesthesia depth during surgery
- Conditions
- Anesthesia, Anesthesia Awareness, Nociceptive Pain, Pediatric ALL
- Trial name
- NCT04826146
- Testing
- Validation of qCON versus BIS
- Where
- 2 sites in Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Patricio Gonzalez Pizarro
Obstetric Anaesthesia With Cardiac Complications
A Superior Anesthetic Technique for the Cesarean Section From a Hemodynamic Perspective.
Cesarean section operations are increasing in rates worldwide. A proper anesthetic technique is required to maintain the safety of both the mother and the fetus.
- Trial name
- NCT04989270
- Testing
- General Anesthesia, Regional Anesthesia
- Where
- Oman
- Volunteers
- 2,500 people
- Sponsor
- Sultan Qaboos University
Awareness, Anesthesia, Arteriovenous Malformations
Awake Craniotomy for Arteriovenous Malformation
The study aimed to retrospectively review cases of brain arteriovenous malformation that were surgical resected with the patient awake during the procedure.
- Trial name
- NCT04949815
- Where
- Pakistan
- Volunteers
- 4 people
- Sponsor
- Aga Khan University
Anesthesia Awareness
Heart Rate Variability to Quantify General Anesthesia Depth
The shortage of anesthetic agents can lead to intraoperative awareness while overdosing can trigger severe intra and postoperative problems.
- Trial name
- NCT04788732
- Testing
- ECG and EEG monitoring
- Where
- Brazil
- Volunteers
- 200 people
- Sponsor
- University of Sao Paulo
Airway Complication of Anesthesia, Peroperative Complication
Comparison of Video Laryngoscopy and Direct Laryngoscopy for Nasotracheal Intubation During Pediatric Dental Surgery
Background and Objective: Airway control is a condition that should be evaluated primarily in anesthesia practice in the pediatric age group.
- Conditions
- Airway Complication of Anesthesia, Peroperative Complication, Intraoperative Hypertension, Tachycardia, Sinus
- Trial name
- Laryngoscopy (NCT04677894)
- Testing
- Laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ordu University