Clinical trials: Intraoperative Analgesia
Osteoarthritis
The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty
The purpose of this study is to use a new combination of anesthesia techniques in an attempt to minimize early pain after surgery and improve the patient's ability to participate more fully with physical therapy.
- Trial name
- NCT00620828
- Testing
- Ropivicaine 0.5%
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Duke University
Pain Management After Surgery
The Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain and Recovery in Children (< 7 Years Old) Undergoing Thoracoscopic Surgery
This study aims to investigate the efficacy of intraoperative intravenous lidocaine infusion on postoperative pain management and recovery in pediatric patients undergoing thoracoscopic pulmonary resection.
- Trial name
- NCT06710405
- Testing
- Lidocaine (drug)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Postoperative Nausea and Vomiting
Dexamethasone, Can it Replace Ketoprofen in the Strategy of Intraoperative Multimodal Analgesia in Paediatric Surgery ? A Prospective Randomized Double-blinded Study. DEXA OP
Postoperative pain and nausea-vomiting (PONV) are the first causes of failure in ambulatory care in pediatric surgery. Actually, the paracetamol/ketoprofen combination in intraoperative care is recommended for effective…
- Trial name
- DEXA OP (NCT02400047)
- Testing
- Dexamethasone 0.2 mg/kg, Dexamethasone 0.4 mg/kg, Ketoprofen 1 mg/kg
- Where
- France
- Volunteers
- 580 people
- Sponsor
- Rennes University Hospital
Pain Management, Spinal Fusion
Intrathecal Morphine Versus Epidural Extended Release Morphine for Pediatric Patients Undergoing Spinal Fusion
This study plans to learn more about preventing pain in children who are having posterior spinal fusion surgery using two different kinds of morphine (a pain medicine).
- Conditions
- Pain Management, Spinal Fusion, Scoliosis
- Trial name
- NCT00880607
- Testing
- Intrathecal morphine, Extended Release Epidural Morphine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Colorado, Denver
Postoperative Pain, Peripheral Neuropathy
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
The main aim of the investigator's study is to propose combination of local anesthetics and adjuvants that provides both adequate anesthesia during surgery and prolonged post-operative analgesia.
- Conditions
- Postoperative Pain, Peripheral Neuropathy, Fractures of the Upper Limb, Fracture of the Lower Limb (Except Hip), Initial Encounter
- Trial name
- DBBA (NCT04498923)
- Testing
- Bupivacaine, dexamethasone, epinephrine
- Where
- Ukraine
- Volunteers
- 68 people
- Sponsor
- Lviv National Medical University
Post Operative Pain, Analgesia
Newborn Infant Parasympathetic Evaluation (NIPE) for Guiding Intraoperative Fentanyl in Children Under 2 Years
During general anesthesia, objective monitoring for analgesia is still lacking. The administration of opioids relies on the experience of the anesthesiologist.
- Conditions
- Post Operative Pain, Analgesia, Children, Only, Narcotic Use
- Trial name
- NCT05758090
- Testing
- NIPE monitor, Control
- Where
- Thailand
- Volunteers
- 70 people
- Sponsor
- Khon Kaen University
Analgesia, Children, Only
The Use of Midazolam as Adjuvant to Bupivacaine Intrathecal Anesthesia for Children Undergoing Lower Abdominal Surgeries.
The study will be carried on children undergoing lower abdominal surgeries. Patients will be randomly categorized into two study groups.
- Conditions
- Analgesia, Children, Only, Bupivacaine, Midazolam
- Trial name
- NCT04718259
- Testing
- intrathecal bupivacaine, midazolam
- Where
- Saudi Arabia
- Volunteers
- 120 people
- Sponsor
- Tanta University
Intraoperative Neurophysiological Monitoring, Pain Management
Effect of a Bolus of Clonidine Systemically Administered on the Excitability of the Spinal Motoneurons of the Lower Extremity
The purpose of this study is to assess the effect of IV clonidine administration on lower limb spinal motoneuron excitability during standardized total intravenous anesthesia (propofol and remifentanil).
- Trial name
- EXCICLON (NCT02592915)
- Testing
- Clonidine hydrochloride, Single bolus of physiologic sodium chloride serum administered IV after induction and obtaining a stable anaesthetic level
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Queen Fabiola Children's University Hospital
Pain, Postoperative, Tonsillar Hypertrophy
Optimization of Pediatric Tonsillectomy to IMprove AnaLgesia
The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery in children and adolescents.
- Conditions
- Pain, Postoperative, Tonsillar Hypertrophy, Tonsillitis, Pediatric Sleep Apnea
- Trial name
- OPTIMAL (NCT06576830)
- Testing
- Methadone, Fentanyl/Hydromorphone
- Where
- United States
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Duke University
Intra-operative Anesthesia and Analgesia Effects
Pediatric Ilioinguinal / Iliohyogogastric Nerve Block
Ilioinguinal / iliohyogogastric nerve blocks; It is frequently used for analgesia and anesthesia in inguinal region surgeons. However, 95% of these surgeons are under general anesthesia.
- Trial name
- NCT02990884
- Testing
- ketamine
- Volunteers
- 60 people
- Sponsor
- Erzincan University
Tonsillitis
Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy
Tonsillectomies are among the most common surgical procedures performed in pediatric populations, with more than 14,000 procedures performed annually in Ontario, with more than 80% being performed to treat sleep-disordered…
- Trial name
- NCT07176533
- Testing
- Suprazygomatic maxillary nerve block (SZMN) with bupivacaine
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Topical Heat Application for Intraoperative Abortion Pain Management
Applied Topical Heat as an Adjunct for Pain Control in First-Trimester Surgical Abortionl
Paracervical blocks are routinely used in first trimester surgical abortions and are a proven method for decreasing procedural pain.
- Trial name
- HAPPE (NCT02536235)
- Testing
- heat
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Analgesia
Opioid Sparing Analgesia: Dexmedetomidine Versus Lidocaine for Intracranial Surgeries in Children
Perioperative pain control is necessary in children as inadequate treatment may lead to progression of perception of pain and development of chronic pain in the future.
- Trial name
- NCT04535089
- Testing
- Dexmedetomidine injection, Lidocaine Iv
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Scoliosis Idiopathic
POSTOPERATIVE OPIOID-SPARING EFFECT OF INTRAOPERATIVE PAIN MONITORING USING THE ANALGESIA NOCICEPTIVE INDEX (ANI) DURING IDIOPATHIC SCOLIOSIS CORRECTION IN CHILDREN.
Anaesthesia is often performed using a balanced technique by administering both opioids and anaesthetics agents. Intraoperative opioid administration is still relying on simple parameters such as heart rate and blood pressure…
- Trial name
- OpiSpANI (NCT04047225)
- Testing
- THE ANALGESIA NOCICEPTIVE INDEX (ANI)
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Arthroplasty, Replacement, Knee
Intraarticular Analgesia After Total Knee Arthroplasty, a Randomised Study
The study aims to compare two different kinds of pain treatment after total knee replacement (operation with artificial knee joint): 1) a large local injection in and around the knee, supplemented with injection the day after, or…
- Trial name
- NCT00269529
- Testing
- femoral nerve block, knee infiltration and injection via catheter
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Acute Pain, Regional Anesthesia
Regional Analgesia in Combination With Cryoanalgesia to Prevent Acute Pain Following Nuss Procedure
Funnel chest deformation is a painful procedure, which requires high doses and long time used of opioids. It makes difficult introduction of ERAS protocol.
- Trial name
- NCT05589246
- Testing
- regional analgesia with cryolesia
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Pomeranian Medical University Szczecin
Intraoperative Pain Control
Transversus Abdominis Plane Block Versus Erector Spina Plane Block
Regional anesthesia and analgesia techniques are frequently used to provide pain control in pediatric surgical applications. The main advantages of these techniques include ease of application, good analgesic efficacy and low…
- Trial name
- NCT04095325
- Testing
- Ultrasound guided erector spinae block
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzincan University
Coarctation of Aorta
The Effect of Paravertebral Block With Dexamethasone on Intraoperative and Postoperative Analgesia in Children Undergoing Surgery for Coarctation of Aorta
Anesthetic management for surgery of aortic coarctation needs special care due to severe pain during lateral thoracotomy incision, the intraoperative hemodynamic instability related to skin incision at lateral thoracotomy…
- Trial name
- NCT03074773
- Testing
- Dexamethasone, ultrasound, paravertebral block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postoperative Pain, Inguinal Hernia Unilateral
Levobupivacaine and Postoperative Pain Relief
The study analysed direct levobupivacaine instillation in surgical wound and its effectiveness in postoperative pain control. Half participants received 0,5 % levobupivacaine and the other half received 0,9% saline solution
- Trial name
- NCT04869046
- Testing
- Instillation of levobupivacaine in surgical wound
- Where
- 2 sites in Serbia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mother and Child Health Institute of Serbia Dr Vukan Cupic
Postoperative Pain
Intraoperative Local Anaesthetic and Postoperative Pain
Background: Intraoperative wound infiltration with local anaesthetic is commonly used. Apart from the obvious immediate action it has been supported that a possible down regulation of pain receptors may lead to longer effects.
- Trial name
- Pain-1 (NCT02171299)
- Testing
- Wound infiltration with local anaesthetic, Ropivacaine
- Where
- Greece
- Volunteers
- 400 people
- Sponsor
- Hellenic Red Cross Hospital