Clinical trials: Intubation
Optic Nerve Sheath Neoplasm, Intracranial Pressure Increase
Optic Nerve Sheath Diameter in Pediatric Patients
Endotracheal intubation and laryngeal mask are generally applied to secure the airway during general anesthesia. There is a widespread opinion among anesthesiologists that endotracheal intubation increases intracranial pressure.
- Conditions
- Optic Nerve Sheath Neoplasm, Intracranial Pressure Increase, Intubation Complication, Airway Complication of Anesthesia
- Trial name
- NCT05445271
- Testing
- Optic nerve sheath diameter measurement with linear ultrasound
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Neonatal Respiratory Distress Syndrome, Gestational Age Conditions
The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST)
The purpose of this study is to evaluate the efficacy and impact of intravenous ketamine or sublingual 30% glucose as sedation drugs used in preterm premature babies during the LISA procedure.
- Trial name
- LISA KGS (NCT04409665)
- Testing
- Ketamine, Glucose
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Medical University of Warsaw
Nasolacrimal Duct Obstruction
Study of Surgical Procedures for Treatment of Persistent Nasolacrimal Duct Obstruction in Children < 4 Years Old
The purpose of this study is: To report the success proportions for the treatment of persistent nasolacrimal duct obstruction for three surgical procedures: balloon catheter dilation, nasolacrimal intubation, and simple probing.
- Trial name
- NLD2 (NCT00315315)
- Testing
- Nasolacrimal balloon catheter dilation, Nasolacrimal intubation, Nasolacrimal duct probing
- Where
- 2 sites in United States
- Volunteers
- 194 people
- Sponsor
- Jaeb Center for Health Research
Failed or Difficult Intubation, Sequela, Intubation; Difficult
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
- Conditions
- Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
- Trial name
- NEAR4KIDs (NCT02493478)
- Where
- 87 sites in United States, Australia and 9 more
- Volunteers
- 150,000 people
- Sponsor
- Children's Hospital of Philadelphia
Intubation; Difficult
Using Lignocaine Spray and Gel to Reduce the Pain Associated With Nasogastric Tube Insertion in Children
Nasogastric tube insertion is one of the most common invasive procedures performed in children's hospitals, and has long been recognised as one of the most traumatic and painful.
- Trial name
- NGTIPPS (NCT01075789)
- Testing
- Lignocaine
- Where
- Australia
- Volunteers
- 13 people
- Sponsor
- The University of Queensland
Endotracheal Intubation
Optimum Dose of Remifentanil for Intubation in Small Children
The routine medications to relax the muscles of the throat are an anesthetic drug, propofol, in combination with an ultra short acting pain medicine, remifentanil.
- Trial name
- NCT00474071
- Testing
- Remifentanil
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Techniques of Endotracheal Intubation in Pediatrics
Re-evaluation of Blind Intubation Through the Air-Q Intubating Laryngeal Airway
To compare the success rate of blind technique with correction manoeuvres versus fiber optic- guided Intubation through the air Q laryngeal airway in pediatric patients
- Trial name
- NCT03778762
- Testing
- Blind tracheal intubation through AirQ, Fiberscopic tracheal intubation through AirQ
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Mansoura University
Intubation; Difficult
Mallampati Classification vs Best Visible Mallampati for Prediction of Difficult Tracheal Intubation
Mallampati score (classification of the visibility of oropharyngeal structures) should be performed in the sitting position, head in the neutral position, mouth widely open, and tongue protrudes, without phonation.
- Trial name
- NCT02788253
- Where
- France
- Volunteers
- 3,244 people
- Sponsor
- University Hospital, Caen
Intubation, Intratracheal
Ultrasound Evaluation of Endotracheal Tube Depth
Correct positioning of the endotracheal tube (ETT) is crucial to ensure safe ventilation. To date, no test that can verify this right after intubation at the bedside exists.
- Trial name
- NCT01649882
- Testing
- US ETT (ultrasound endotracheal tube)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kai Schoenhage
Hypoxemia
Neuromuscular-Blocking Agents and Hypoxemia During Intubation in Infants (ROC-HYPOX)
The prevention of the occurrence of respiratory events is a constant concern in pediatric anesthesia, as these represent the main cause of the anesthesic mortality.
- Trial name
- ROC-HYPOX (NCT02589691)
- Testing
- Rocuronium, Sodium chloride 0.9%
- Where
- 6 sites in France
- Volunteers
- 412 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Newborn, Preterm
Influence of Premedication Protocols for Neonatal Endotracheal Intubation on Cerebral Oxygenation
The purpose of this study is to examine the influence of premedication drugs Atropin, Fentanyl and Mivacurium and of endotracheal intubation on cerebral oxygenation and cardiac output in term and preterm newborn infants.
- Conditions
- Newborn, Preterm, Intubation
- Trial name
- NCT01427985
- Testing
- Atropine, Fentanyl, Mivacurium
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- University of Ulm
Intubation; Difficult, Cervical Spine Injury
Head Motion in Pediatric Patients Endotracheally Intubated With Video Laryngoscopy Versus Direct Laryngoscopy
The purpose of this study is to evaluate if intubation with video laryngoscopy (VL) will result in less head motion and therefore less cervical motion when compared with direct laryngoscopy (DL).
- Trial name
- NCT02405390
- Testing
- Video Laryngoscopy, Direct Laryngoscopy, Storz C-Mac® laryngoscope
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Nicklaus Children's Hospital f/k/a Miami Children's Hospital
Airway Management, Emergency
Prehospital Emergency Airway Research.
The creation of an airway registry will allow an improvement in the quality of care, the safety of critically ill patients in pre-hospital situations, and a reduction in morbidity and mortality related to airway management.
- Trial name
- PhEAR (NCT07289139)
- Where
- Spain
- Volunteers
- 4,300 people
- Sponsor
- Centro de Emergencias Sanitarias 061 Andalucía
Intubation;Difficult
Glottic View in Infants With a Shoulder Roll
This study compares the distance from the operating table to the eye of the laryngoscopist while intubating the trachea with or without a shoulder roll.
- Trial name
- NCT03424070
- Testing
- Shoulder Roll
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Difficult or Failed Intubation
A Comparison Between Using Video Stylet and Video Laryngoscope in Difficult Intubation of Traumatic Patients .
The aim of this study is to compare the visualization of the glottis, the time for tracheal intubation, the success rate of intubation, and the need for manoeuvres to optimize the view using video stylet or video laryngoscope in…
- Trial name
- NCT05143346
- Testing
- Intubation
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Endotracheal Intubation, Gastrointestinal Endoscopy
Application of Lateral Position Digestive Endoscopy-Guided Endotracheal Intubation in Anesthesia for Endoscopic Diagnosis and Therapy
This case series study evaluated whether placing a breathing tube using a camera (gastrointestinal endoscope) is safe and effective for patients lying on their left side during stomach and intestine exams under anesthesia.
- Conditions
- Endotracheal Intubation, Gastrointestinal Endoscopy, Airway Management, Lateral Position
- Trial name
- NCT06990490
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Changlong Qiao
Intubation; Difficult
Videolaryngoscopy in Patients With Cervical Spine Immobilisation
Tracheal intubation is more difficult in patients in whom cervical spine immobilisation is maintained during tracheal intubation. The McGrath Series 5 videolaryngoscope offers a potential solution.
- Trial name
- NCT02563301
- Testing
- Laryngoscopy
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- NHS Tayside
Intubation Complication
Effect of Benzydamine Hydrochloride to Postoperative Sore Throat in Pediatric Patients
This study is designed to examine the effect of benzydamine hydrochloride to postoperative sore throat in pediatric patients. We will spray benzydmaine hydrochloride or normal saline at oral cavity and the tip of endotracheal…
- Trial name
- NCT03074968
- Testing
- Benzydamine Hydrochloride, Normal saline
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Seoul National University Hospital
Airway Management
Apneic Intubation Critically Ill Children
This study compares the actual standard of care of intubation in Swiss pediatric intensive care units vs the use of apneic oxygenation using either high flow or low flow oxygen to prevent hypoxemia and to prolong apnea time…
- Trial name
- Penguin (NCT04890288)
- Testing
- Interventional randomized controled trial (RCT) comparing two oxygenation methods to reduce desaturation during intubation vs standard of care.
- Where
- 7 sites in Switzerland
- Volunteers
- 210 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Flexible Bronchoscopy, Simulation Training
Learning-curve-based Simulation Training for Bronchoscopic Intubation
This study aims to determine whether a new learning-curve-based simulation training modality could contribute to a noninferiority regarding bronchoscopic-guided intubation time in patients compared with the reference…
- Conditions
- Flexible Bronchoscopy, Simulation Training, Intubation Time
- Trial name
- NCT05383729
- Testing
- learning-curve-based training modality, fixed-training-time training modality
- Where
- 2 sites in China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital