Clinical trials: Investigation Time
Congenital Heart Disease
Real-time 3-Dimensional Echocardiography for Assessment of Cardiac Function and Congenital Heart Disease
The propose of this study is to generate normative data of the tree-dimensional echocardiographic(3-DE) measurements for cardiac structure and function in a large cohort of normal infants, children,and adolescents.
- Trial name
- 3DE-CHD (NCT01300221)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Drexel University
Daytime Wetting, Enuresis
Voiding School as a Treatment of Children's Day-time Incontinence or Enuresis
The Voiding School is a simple educational intervention to treat children with daytime incontinence or enuresis.The purpose of this study is to implement the intervention in primary care, child welfare clinics.
- Conditions
- Daytime Wetting, Enuresis, Functional Incontinence
- Trial name
- NCT03478813
- Testing
- Voiding school
- Where
- Finland
- Sponsor
- Helsinki University Central Hospital
Cataract
Effective Phaco Time and Endothelial Cell Loss When Using Veritas
This study is a single center, prospective study of cumulative dissipated energy and endothelial cells loss per phacoemulsification procedure after successful cataract surgery.
- Trial name
- NCT07176416
- Testing
- Veritas Vision System
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Aloha Vision Consultants
Infantile Colic
Evaluation of Safety and Efficacy of New Infant Formula in Infantile Colic
The study is conducted to examine the safety and efficacy of a new infant formula and its effects on the gastrointestinal tolerance in infants suffering from colic.
- Trial name
- Coco (NCT01721850)
- Testing
- control formula, intervention formula 1, intervention formula 2
- Where
- 18 sites in Germany, Italy
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- HiPP GmbH & Co. Vertrieb KG
Myopia
Multicenter Evaluation of Near Vision and Outdoor Time in Kids Study
Currently, optical and pharmacological interventions have been developed to prevent the progression of childhood myopia. However, no myopia control strategy has been shown to have complete efficacy in controlling myopia…
- Trial name
- MENOK (NCT06119243)
- Testing
- Vivior
- Where
- 5 sites in United States, Australia
- Volunteers
- 230 people
- Sponsor
- The University of New South Wales
Instrumentation Time
Comparative Evaluation of Instrumentation Time Using Pediatric Rotary Versus Hand (Flare) File Systems
The study will be conducted to evaluate instrumentation time, obturation quality, and child's behavior using pediatric rotary versus hand flare file systems in treatment of primary molars.
- Trial name
- NCT05665803
- Testing
- Pediatric rotary files, Manual flare files
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pediatric Obesity
Monitoring Eating Across Locations (MEAL) - Timing, Intake, and Mealtime Evaluation (TIME)
Increased availability of high-energy dense foods has contributed to a pediatric obesity epidemic, with 23% of United States children currently presenting with the disease.
- Trial name
- MEAL-TIME (NCT07095166)
- Testing
- Meal Location
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Penn State University
HCV
A Clinical Trial of 16 Weeks of Duration to Evaluate Retreatment With Elbasvir/Grazoprevir Plus Sofosbuvir and Ribavirin in Patients With Chronic Hepatitis C Genotypes 1,4 Who Have Failed to Treat With a Regime Based on an Inhibitor of the NS5A
This is a phase 4 clinical trial to treat patients who have failed to treat with regimen based on an inhibitor of the NS5A
- Trial name
- C-RESCUE (NCT03105349)
- Testing
- elbasvir/grazoprevir, Sofosbuvir, Ribavirin
- Where
- 5 sites in Spain
- Sponsor
- Fundacion SEIMC-GESIDA
Allergic Conjunctivitis
A Multi-Center Study Evaluating the Onset and Duration of Action of AC-170 0.24% Compared to Vehicle in the Conjunctival Allergen Challenge (CAC)
The purpose of this study is to evaluate the onset and duration of action of AC-170 0.24% compared to vehicle in the prevention of the signs and symptoms of allergic conjunctivitis in the conjunctival allergen challenge (CAC)…
- Trial name
- NCT01551056
- Testing
- AC-170 0.24%, AC-170 0%
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Aciex Therapeutics, Inc.
Midazolam
Pharmacokinetic Evaluation of MDZ028
Plasma concentration data were collected from 37 paedriatic patients and 12 healthy adults recruited in a single dose, open-label phase II pharmacokinetic study and in a single dose, randomised, open-label two-peiod crossover…
- Trial name
- MIDAZOLAM (NCT03639428)
- Testing
- Midazolam
- Volunteers
- 37 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Osteogenesis Imperfecta
Multicenter,Single-arm Study to Evaluate Efficacy, Safety, & Pharmacokinetics of Denosumab in Children w/ OI
This is a prospective, multicenter, single-arm study in children 2 to 17 years of age with OI to evaluate efficacy and safety of denosumab.
- Trial name
- OI (NCT02352753)
- Testing
- Denosumab
- Where
- 49 sites in United States, Australia and 11 more
- Volunteers
- 153 people
- Sponsor
- Amgen
Screen Time Exposure
Reactions to Social Media Warning Labels Among Teens and Young Adults
The primary objective of this study is to evaluate whether social media warnings are perceived as more effective than control labels among teens and young adults, and to identify the most promising topics for social media…
- Trial name
- NCT07199660
- Testing
- Human-developed negative body image warning, Voluntary warning, Human-developed depression and anxiety warning
- Where
- United States
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- Stanford University
Yoga, ADHD
Investigation of the Effect of Yoga on Balance, Reaction Time and Agility in Children With ADHD
Purpose: To determine the effect of 8-week kids yoga training on balance, reaction time and agility on children diagnosed with attention deficit hyperactivity disorder (ADHD). Method: A randomized controlled trial.
- Conditions
- Yoga, ADHD, Balance, Children, Only
- Trial name
- NCT05742451
- Testing
- kids yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Ankara Medipol University
Chronic Idiopathic Urticaria
A Study to Evaluate the Efficacy, Response Duration and Safety of Xolair (Omalizumab) in Patients With Chronic Idiopathic Urticaria (CIU)/Chronic Spontaneous Urticaria (CSU) Who Remain Symptomatic Despite Antihistamine Treatment (H1)
The study is a global Phase III, multicenter, randomized, double-blind, placebo-controlled, parallel-group study to evaluate the efficacy and safety of omalizumab administered subcutaneously as an add-on therapy for the treatment…
- Trial name
- NCT01292473
- Testing
- Omalizumab
- Where
- 61 sites in United States, Denmark and 6 more
- Volunteers
- 323 people
- Sponsor
- Genentech, Inc.
Fluid and Electrolyte Imbalance, Fluid Therapy
Correlation Between Duration of Fasting and Response to Fluid Replenishment, Evaluated With Repeated Measures of VTI.
The investigators will study the correlation between the lenght of the fasting before surgery and the need to replenish with intra-venous fluids in children, evaluated with 3 measures of the aortic Integral Time Velocity with…
- Trial name
- NCT03599973
- Testing
- Plasmalyte A Viaflo
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Conjunctivitis, Allergic
A Study to Evaluate the Duration of LASTACAFT® in Acute Allergic Conjunctivitis
This study will evaluate the duration of action of LASTACAFT® and Pataday™ as compared to artificial tears (placebo) in the prevention of ocular itching associated with allergic conjunctivitis.
- Trial name
- NCT01470118
- Testing
- alcaftadine 0.25% ophthalmic solution, olopatadine 0.2% ophthalmic solution, dextran 70 0.1%/hydroxypropyl methylcellulose 0.3%
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- Allergan
Artificial Intelligence
A Study to Assess the Impact of an Artificial Intelligence (AI) System on Chest X-ray Reporting
The study has an initial short retrospective component but is predominately a prospective study with two main parts. Initially during a 1 month period whilst reporters are familiarising themselves with the software two local…
- Trial name
- NCT05489471
- Testing
- Artificial intelligence review
- Volunteers
- 20,000 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Type 1 Diabetes
Study of Insulin Therapy Augmented by Real Time Sensor IN Type 1 Children and Adolescents (START-IN!)
Glycemic control in children and adolescent with type 1 diabetes remains inadequate, exposing them to the risk of vascular complications in adulthood.
- Trial name
- START-IN (NCT00949221)
- Testing
- monitor Paradigm 754 VEO, MINILINK Real Time, Medtronic, CE
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Candidiasis, Oral, HIV Infections
The Safety and Effectiveness of Peridex in Preventing or Delaying Fungal Infections of the Mouth in HIV-Infected Patients
To evaluate the safety and effectiveness of Peridex (an oral rinse containing chlorhexidine gluconate) for preventing the occurrence of clinically-evident microbiologically-documented oral candidiasis in HIV-positive patients…
- Trial name
- NCT00002431
- Testing
- Chlorhexidine gluconate
- Where
- 5 sites in United States
- Sponsor
- Procter and Gamble
Human Papillomavirus Virus
Observational Follow up of Prior HPV Vaccinees
HPV vaccines have been included in the national immunisation schedule since 2008, firstly as the Cervarix vaccine which protects against two HPV types and in 2012 as the Gardasil vaccine which offers protection against a further…
- Trial name
- HPVfollowup (NCT02811068)
- Testing
- venepuncture
- Where
- 2 sites in United Kingdom
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Public Health England