Clinical trials: Investigation Time
Influenza
A Study of Tamiflu (Oseltamivir) for Treatment of Influenza With a Focus on (H1N1) 2009 Flu Strain
This randomized, double-blind, multi-center study of Tamiflu (Oseltamivir) will evaluate the efficacy against viral activity, the effectiveness in resolving the disease symptoms, and the safety and tolerability in patients with…
- Trial name
- NCT01032837
- Testing
- Oseltamivir
- Where
- 100 sites in United States
- Volunteers
- 102 people
- Sponsor
- Hoffmann-La Roche
Brain Tumors, Solid Tumor
Understanding Communication in Healthcare to Achieve Trust (U-CHAT)
Honest, clear, and empathetic communication between pediatric oncologists (POs) and parents of children with cancer (POCCs) is imperative to facilitating therapeutic alliance and ensuring that medical management aligns with the…
- Trial name
- NCT02846038
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- St. Jude Children's Research Hospital
Spontaneous Breathing Test, Infants
Positioning and the Spontaneous Breathing Test in Neonates
The spontaneous breathing test (SBT) is routinely performed on all intubated patients in the NICU who are potential candidates for extubation from mechanical ventilatory support.
- Conditions
- Spontaneous Breathing Test, Infants, NICU
- Trial name
- NCT01953562
- Sponsor
- Christiana Care Health Services
Cystic Fibrosis
Gut Imaging for Function & Transit in CF - GIFT-CF 3
An observational study of patients with cystic fibrosis (CF) starting treatment with Kaftrio (Elexacaftor / Tezacaftor / Ivacaftor) as part of routine clinical care, following EMA licensing (approved end of Aug 2020).
- Trial name
- GIFT-CF3 (NCT04618185)
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Bracket Failure Rate, Bonding Time Per Bracket
Is a Primer Needed for Orthodontic Bonding? A Multi-centre Trial
Orthodontic treatment is carried out by placing fixed attachments(brackets)on teeth with wires which run through them and create tooth movement.
- Conditions
- Bracket Failure Rate, Bonding Time Per Bracket, Adhesive Remnant Index for Type of Bond Failure, Length of Treatment
- Trial name
- NCT01782521
- Testing
- No primer
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Bradford Teaching Hospitals NHS Foundation Trust
Acute Blunt Soft Tissue Injuries/Contusions
Efficacy and Safety of Diclofenac Sodium Topical Gel 1% Compared to Placebo in Subjects With Acute Blunt Trauma Injuries
This study will assess the analgesic efficacy of DSG 1% compared to placebo in the reduction of the pain associated with acute blunt trauma injuries.
- Trial name
- NCT02290821
- Where
- 10 sites in United States
- Volunteers
- 215 people
- Sponsor
- Novartis
Mortality, Pediatric
Operative Duration as a Predictor of Mortality in Pediatric Emergency Surgery
Introduction Operative duration is an important but under-studied predictor of mortality in emergency laparotomies. Aims \& Objectives The objective of this study was to quantify the effect of duration of emergency laparotomy in…
- Conditions
- Mortality, Pediatric, Laparotomy, Emergencies
- Trial name
- NCT03270930
- Testing
- Emergency laparotomy
- Volunteers
- 213 people
- Sponsor
- Jawaharlal Nehru Medical College
Mild and Moderate Atopic Dermatitis Patients, Atopic Dermatitis (AD)
Clinical Trial of an Ointment in Patients With Mild and Moderate Atopic Dermatitis
Atopic dermatitis (AD) is a chronic skin disorder, which negatively impacts up to 20% children and 3% adults in the world. The main AD treatments aim to regress clinical manifestations, improve and restore skin lesions.
- Trial name
- NCT07653386
- Testing
- S.formosum-containing ointment, commercial moisturizer
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- VinUniversity
Fluid and Electrolyte Imbalance, Fluid Therapy
Correlation Between Duration of Fasting and Response to Fluid Replenishment, Evaluated With Repeated Measures of VTI.
The investigators will study the correlation between the lenght of the fasting before surgery and the need to replenish with intra-venous fluids in children, evaluated with 3 measures of the aortic Integral Time Velocity with…
- Trial name
- NCT03599973
- Testing
- Plasmalyte A Viaflo
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Bronchiectasis
Evaluation of Motor Imagery, Cognitive Function and Reaction Time in Children With Bronchiectasis
The aim of this study was to evaluate motor imagery ability, reaction time and cognitive function parameters in children with CF and non-CF bronchiectasis compared to healthy peers.
- Trial name
- NCT06630403
- Testing
- Demographic Data, Disease History, Pulmonary Function Test
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University
Diabetes type1
Simple Initiation of Advanced Hybrid Closed Loop System
Background and Aim. The new and advanced hybrid closed loop (AHCL) system MiniMed 780G automatically adjusts basal insulin delivery in addition to automated bolus corrections, based on continuous glucose monitoring (CGM)…
- Trial name
- 780GGS (NCT05069727)
- Testing
- Regular Protocol with advanced carbohydrate counting, Simplified Protocol with fixed carbohydrate content
- Where
- Qatar
- Volunteers
- 34 people
- Sponsor
- Sidra Medicine
Physical Activity
Long-term Impact of PE Teacher Interventions on Adolescent Leisure Time Activity and Motivation
This project aims to develop a three-month face-to-face and web-based intervention program for physical education (PE) teachers to increase autonomy, competence, and relatedness supportive behaviour toward their students and to…
- Trial name
- NCT06768788
- Testing
- Face-to-face and web-based need-supportive intervention program based on the main tenets of SDT in the field of PE 1, Face-to-face and web-based need-supportive intervention program based on the main tenets of SDT in the field of PE 2
- Where
- Estonia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Premature Birth
Assessment of Factors Influencing Parents' Attendance Time During Feeding Time of Premature Infants Born Before 35 Weeks of Amenorrhea in Besançon University Hospital
The precise description of parental presence and the associated factors will make it possible to construct an intervention in order to correct potentially low parental participation.
- Trial name
- PréPaLim (NCT05177913)
- Where
- France
- Volunteers
- 75 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Pharyngitis, Tonsillitis
APC-111 Once a Day (QD) for 7 Days vs. Penicillin Taken Four Times a Day (QID) for 10 Days in Patients With Strep Throat
The purpose of the this study is to evaluate the safety of efficacy of APC-111 775 mg MP tablet once daily dosing for 7 days for treating patients with strep throat.
- Trial name
- NCT00095368
- Testing
- Amoxicillin Pulsatile Release Multiparticulate Tablet (drug)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Advancis Pharmaceutical Corporation
Myopia
Multicenter Evaluation of Near Vision and Outdoor Time in Kids Study
Currently, optical and pharmacological interventions have been developed to prevent the progression of childhood myopia. However, no myopia control strategy has been shown to have complete efficacy in controlling myopia…
- Trial name
- MENOK (NCT06119243)
- Testing
- Vivior
- Where
- 5 sites in United States, Australia
- Volunteers
- 230 people
- Sponsor
- The University of New South Wales
Central Venous Catheter
Evaluation of Performance Over Dwell Time and Safety of the Central-venous Catheters Certofix® Paed
Central venous catheterisation is a medical technique that has become established over many decades and can be rated as State of the Art.
- Trial name
- NCT05124821
- Testing
- Central venous catheter intended to be used for children during routine clinical practice
- Where
- 3 sites in Germany, Italy
- Volunteers
- 100 people
- Sponsor
- B. Braun Melsungen AG
Patent Ductus Arteriosus
Paracetamol Treatment of the Borderline Significant PDA
The therapeutic approach to the patent ductus arteriosus (PDA) in the premature neonate remains controversial. Currently it is generally accepted to treat only hemodynamically significant PDAs.
- Trial name
- NCT02819414
- Testing
- Paracetamol drops
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Shaare Zedek Medical Center
Bronchiolitis
Bronchiolitis: Evaluation of Wang's Score as a Predictor of the Duration of Oxygen Therapy in Bronchiolitis
Evaluation of Wang's score as a predictor of the duration of oxygen therapy in bronchiolitis
- Trial name
- NCT03362125
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Rennes University Hospital
Musculoskeletal Abnormality, Pediatric
Reliability and Acceptability of Real-time Virtual Video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
The use of telemedicine in musculoskeletal assessment has been historically low. The current COVID 19 global pandemic has forced a paradigm shift with many centers rapidly adopting virtual visits to conduct care resulting in…
- Trial name
- NCT04668820
- Testing
- video Pediatric Gait, Arms, Legs and Spine (V-pGALS)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Marmara University
Pediatric Obesity
Monitoring Eating Across Locations (MEAL) - Timing, Intake, and Mealtime Evaluation (TIME)
Increased availability of high-energy dense foods has contributed to a pediatric obesity epidemic, with 23% of United States children currently presenting with the disease.
- Trial name
- MEAL-TIME (NCT07095166)
- Testing
- Meal Location
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Penn State University