Clinical trials: Ivf
ART, IVF
Health in Childhood Following Assisted Reproductive Technology
The purpose of this trial is to investigate the metabolic and cardiovascular health in children aged 6-8 years born after in-vitro fertilization with frozen embryo transfer
- Conditions
- ART, IVF, Cardiovascular Risk Factor, Hypertension
- Trial name
- HiCART (NCT03719703)
- Where
- Denmark
- Volunteers
- 606 people, healthy volunteers welcome
- Sponsor
- Anja Bisgaard Pinborg
Fertilization in Vitro
Designated Drug Use Investigation 1 of Follistim Injection (Study P06130)(COMPLETED)
To evaluate dosage and administration method, efficacy and safety of Puregon and the relationship between background factors of patients and dose and administration method.
- Trial name
- NCT00920361
- Testing
- Follitropin beta
- Volunteers
- 1,664 people
- Sponsor
- Organon and Co
Assisted Reproductive Techniques, Pregnancy
Incidence of Pulmonary and Venous Thromboembolism in IVF Pregnancies After Fresh and Frozen Embryo Transfer
In vitro fertilization (IVF) is associated with an increased risk of venous thromboembolism and in particular pulmonary embolism during the first trimester.
- Conditions
- Assisted Reproductive Techniques, Pregnancy, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- NCT03660007
- Testing
- Fresh or frozen embryo transfer IVF
- Volunteers
- 902,891 people
- Sponsor
- Karolinska Institutet
Infertility Unexplained, Fertility Disorders
Hypnofertility for Women Undergoing In Vitro Fertilization (HWUIVF)
This randomized controlled study aimed to specify whether the interventions based on Hypnofertility would lead to increased fertility preparedness and pregnancy outcomes, decreased cortisol levels of women undergoing In Vitro…
- Trial name
- NCT04141436
- Testing
- Interventions Based on Hypnofertility, Routine clinical procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, Female
Heated and Non Heated Ovarian Aspiration Needle Protocol
The success of IVF is influenced by factors as cause of infertility and age. Furthermore, there is a large influence of external factors, from the laboratory environment, handling and cultivation of gametes and embryos.
- Trial name
- NCT05683639
- Testing
- warming of the follicular aspiration needle
- Where
- Brazil
- Volunteers
- 179 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Infertility
An Observational Study of Cetrotide® Gonadotropin-releasing Hormone Antagonist (GnRH Antagonist) With GONAL-f® in Assisted Reproductive Technologies (ART)
This is a multicentric, prospective, observational study on the use of Cetrotide to control the endogenous gonadotrophin levels in Gonal-f stimulated ART treatment cycles in the Asia-Pacific region.
- Trial name
- NCT01109654
- Testing
- Cetrorelix acetate and Follitropin alfa
- Where
- Singapore
- Volunteers
- 2,175 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
IVF, Infertility Treatment
Biomarkers of Endometrial Receptivity
Analysis of proteins from cervical mucus will be done in patients undergoing infertility treatment (fresh or frozen embryo transfer). Cervical mucus will be analysed for potential new biomarkers of endometrium receptivity.
- Conditions
- IVF, Infertility Treatment, Fertility Disorders, Embryo Transfer
- Trial name
- BIOMER (NCT04619524)
- Testing
- Cervical mucus will be collected from patients undergoing IVF, Cervical mucus will be collected from patients undergoing transfer of cryopreserved embryos
- Where
- 3 sites in Czechia
- Volunteers
- 476 people
- Sponsor
- The Institute of Molecular and Translational Medicine, Czech Republic
Fertilization in Vitro
Virtual Reality-Supported Hypnofertility
This research was conducted to determine the effect of virtual reality-supported hypnofertility on fertility preparedness, stress and coping with stress in women having in vitro fertilization.
- Trial name
- NCT04755270
- Testing
- VR Glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people
- Sponsor
- Adiyaman University
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Fertility Disorders
Natural Frozen Embryo Transfer (FET) vs Substituted Frozen Embryo Transfer (FET)
In frozen embryo transfer substituted cycles, patients are treated with progesterone and estrogen in an attempt to mimic the natural cycle and a transfer is planned whenever the endometrium is ready.
- Trial name
- NCT06053827
- Testing
- Frozen embryo transfer
- Where
- Canada
- Volunteers
- 1,207 people
- Sponsor
- Clinique Ovo
Diabetic Ketoacidosis
Double Blinded Randomized Control Trial of Types of IVF in Children With DKA
Objectives: Intravenous (IV) fluid administration is a fundamental component of diabetic ketoacidosis (DKA) treatment. Normal saline (NS), the most common IV fluid used in DKA management, contains more chloride than human blood.
- Trial name
- NCT03066440
- Testing
- Normal saline, Lactated Ringers
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- State University of New York at Buffalo
Infertility
Comparison of Assisted Reproductive Technology (ART) Outcomes Between Two Protocols of Induction of Ovulation in Patients With Hypogonadotropic Hypogonadism
We wanted to compare the Assisted Reproductive Technology (ART) outcomes between two protocols of induction of ovulation in patients with Hypogonadotropic Hypogonadism.
- Trial name
- NCT02140515
- Testing
- Lutropin alfa, Follitropin alfa and Lutropin alfa
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Royan Institute
Infertility, Genetic Disease
Follow-up With Preimplantation Genetic Testing Patients
The main purpose of this study is to perform longitudinal evaluations of clinical outcomes and personal perspectives following utilization of preimplantation genetic testing (PGT).
- Conditions
- Infertility, Genetic Disease, IVF
- Trial name
- NCT04477863
- Testing
- Follow-up Interview
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- Genomic Prediction Inc.
Infertility, IVF
Health of Babies Born From IVF Versus IVM at 5 Years Old
The investigators conduct a long-term follow-up at five years on offspring born from our randomized controlled trial (RCT) to investigate whether or not there is any difference in developmental outcomes in children born after…
- Conditions
- Infertility, IVF, IVM, Development, Child
- Trial name
- FM-BABIES-5Y (NCT06369415)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3 and behavioural screening according to Strength and Difficulties Questionnaires (SDQ's)
- Where
- Vietnam
- Volunteers
- 214 people
- Sponsor
- Mỹ Đức Hospital
Fertility Disorders
Effect of Oocyte Denudation Time and Intracytoplasmic Sperm Injection Time on Embryo Quality
An observational analytic retrospective study was conduct using cross-sectional study. The subject were oocytes from in-vitro fertilization procedures using the ICSI method at the assisted reproductive technology clinic in a…
- Trial name
- NCT05448859
- Testing
- intracytoplasmic sperm injection
- Volunteers
- 200 people
- Sponsor
- Universitas Padjadjaran
Activation of Primordial Follicles
Ovarian Needle Puncture for Follicle Activation in IVF Patients With Diminished Ovarian Reserve
Premature ovarian insufficiency (POI), is cessation of ovarian function characterized by hypergonadotropic amenorrhea and hypoestrogenic syndrome before 40 years of age.
- Trial name
- NCT04608695
- Testing
- Ovarian puncture
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hacettepe University
Fertility Preservation
Oocyte Vitrification for In Vitro Fertilization (IVF) Patients and Women With Fertility Threatening Conditions
Vitrification is a method of cryopreserving tissue for future use. It is widely used to preserve extra, good quality embryos generated from infertility treatments.
- Trial name
- NCT01448460
- Volunteers
- 8 people
- Sponsor
- University of Louisville
Healthy Volunteers
Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants
This study collects data on microbiological, genetic and environmental factors, as well as lung function parameters (e.g. spirometry, body plethysmography, lung-MRI) to assess the complex interaction of predisposing risk factors…
- Trial name
- NCT04286464
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Azoospermia, Infertility
Microdissection Testicular Sperm Extraction (MicroTESE) and IVF-ICSI Outcome in Non-Obstructive Azoospermia (NOA)
We evaluated the application of surgical testicular exploration with the aid of a microscope (MictoTESE) to increase the chances of obtaining sperm in men with impaired sperm production, a condition known as non-obstructive…
- Trial name
- NCT00484081
- Testing
- Microdissection Testicular Sperm Extraction, ICSI
- Where
- Brazil
- Volunteers
- 53 people
- Sponsor
- Clinic and Research Center in Human Reproduction Roger Abdelmassih