Clinical trials: Jaundice
Indirect Hyperbilirubinemia, Neonatal
COMPARISON OF ZINC AND PROBIOTICS ON NEONATES WITH INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY
Study will evaluate effects of oral zinc and probiotics supplementation in neonates who have indirect hyperbilirubinemia and are receiving phototherapy.
- Trial name
- ZIPP (NCT07102836)
- Testing
- Zinc sulfate, Probiotic lactobacillus rhamnosus GG
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Quaid-e-Azam Medical College
Neonatal Jaundice
Reliability of Transcutaneous Bilirubin Measurement According to the Skin Colour of Newborns
Neonatal jaundice is a physiological process characterized by a yellow coloration of the skin and mucous membranes linked to an increase in a pigment: bilirubin.
- Trial name
- BILICOLOR (NCT07315126)
- Testing
- Skin color assessment
- Where
- France
- Volunteers
- 510 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hemolytic Disease of Newborn, Neonatal Hyperbilirubinemia
Safe Threshold to Discontinue Phototherapy in Hemolytic Disease of Newborn
We hypothesized that adopting a lower rather than a higher threshold for phototherapy discontinuation will be associated with reduced rates of rebound hyperbilirubinemia in term and late preterm neonates with hemolytic disease of…
- Trial name
- NCT04218318
- Testing
- phototherapy
- Where
- Saudi Arabia
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Saudi Arabia
Pancreatic Neoplasms, Biliary Tract Neoplasms
Comparing Endoscopic Based Stent Strategy Versus Bypass Surgery in Non-resectable Periampullary Cancer
Randomized study comparing endoscopic stent insertion strategy versus double-bypass surgery in non-resectable periampullary cancer
- Conditions
- Pancreatic Neoplasms, Biliary Tract Neoplasms, Duodenal Neoplasms
- Trial name
- NCT00487851
- Testing
- surgery, endoscopic strategy
- Where
- Sweden
- Sponsor
- Karolinska Institutet
Neonatal Hyperbilirubinemia, Rebound Hyperbilirubinemia
Predictors of Rebound Hyperbilirubinemia Study
## Brief Summary Neonatal hyperbilirubinemia is one of the most common causes of neonatal hospitalization and phototherapy treatment.
- Trial name
- NCT07694635
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Haseki Training and Research Hospital
Neonatal Hyperbilirubinemia
Newborn Jaundice - An Investigation of Different Approaches to Light Therapy
Background Neonatal jaundice affects about 60% of full-term newborns in their first week. If untreated, it can lead to permanent brain damage. In Denmark, 2-5% of newborns require phototherapy, the standard treatment.
- Trial name
- NCT06702241
- Testing
- Continuous Phototherapy with a irradiance of 40 µW/cm2/nm from the overhead light, Continuos Phototherapy with a irradiance of 55 µW/cm2/nm from the overhead light, Continuous Phototherapy with a irradiance of 70 µW/cm2/nm from the overhead light
- Where
- 2 sites in Denmark
- Volunteers
- 116 people
- Sponsor
- Regionshospital Nordjylland
Hyperbilirubinemia, Neonatal
Screening and Follow-up Study of Neonatal Jaundice Based on Mobile Network
At least 13 hospitals in China will participate in the study, which aims to clarify the natural history of jaundice in Chinese healthy newborns，and decrease the incidence of severe hyperbilirubinemia and acute bilirubin…
- Trial name
- NCT04251286
- Where
- China
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Jaundice Neonatal
The Risk of Hyperbilirubinemia in Term Newborns After Placental Transfusion
Delayed cord clamping (DCC) has been a subject of extensive research for the last couple of years. Based on published data, numerous neonatal benefits have been suggested such as increased hemoglobin and ferritin levels both at…
- Trial name
- NCT02625688
- Testing
- Delayed cord clamping, Cord milking, Early cord clamping
- Where
- Poland
- Volunteers
- 400 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Obstructive Jaundice
Diagnostic Accuracy of Magnetic Resonance Cholangiopancreatography in Patients With Obstructive Jaundice
Evaluate the diagnostic accuracy of Magnetic Resonance Cholangiopancreatography (MRCP) compared with Ultrasound and Computed Tomography (CT) in patients with obstructive jaundice taking findings of ERCP/ PTC and histopathology as…
- Trial name
- NCT06754397
- Testing
- Magnetic Resonance Cholangiopancreatography
- Volunteers
- 50 people
- Sponsor
- Sohag University
Jaundice, Neonatal, Neonatal Hyperbilirubinemia
Comparison of Phototherapy Using Neolight Skylife Versus Standardized Phototherapy for Hyperbilirubinemia in Newborns
Phototherapy has served as a primary treatment for hyperbilirubinemia in newborn populations. The light emitted through phototherapy interacts with bilirubin at the skin level to transform it into water-soluble products…
- Conditions
- Jaundice, Neonatal, Neonatal Hyperbilirubinemia, Neonatal Disorder
- Trial name
- NCT03599258
- Testing
- Skylife, Standard Therapy
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- HonorHealth Research Institute
Neonatal Hyperbilirubinemia
Investigation Into the Dynamic Variations of End-Tidal Carbon Monoxide Concentration (ETCOc) in Neonates Utilizing Non-Dispersive Infrared Spectroscopy and Its Implications for Jaundice Management
The objective of this study is to ascertain the diagnostic threshold of end-tidal carbon monoxide (ETCOc, adjusted for ambient CO levels) within the first three days postpartum, stratified by neonatal age at birth.
- Trial name
- ETCO (NCT07346976)
- Testing
- Erythrocyte Life Span Tester
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Newborn Jaundice
Effect of Tub Bathing on Skin and Bilirubin Levels in Infants Undergoing Tunnel and LED of Phototherapy
The study was conducted as a randomized controlled study to determine effect of tube bathing on skin and bilirubin levels in infants undergoing tunnel and LED of phototherapy.
- Trial name
- NCT04962113
- Testing
- TUBE BATH
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Istanbul University - Cerrahpasa
Cholangitis, Secondary Biliary, Cholangiocarcinoma
Advanced Endoscopy During COVID-19
In this study, investigators aim to explore the status of advanced endoscopy in different endoscopy units all over the world.
- Conditions
- Cholangitis, Secondary Biliary, Cholangiocarcinoma, Obstructive Jaundice, Pancreas Cancer
- Trial name
- NCT04385147
- Testing
- Endoscopic management according to standard of care
- Where
- 5 sites in United States, Egypt and 3 more
- Volunteers
- 670 people
- Sponsor
- Al-Azhar University
Indirect Hyperbilirubinemia
Efficacy of Bifidobacterium Animalis Subsp. Lactis in the Treatment of Indirect Hyperbilirubinemia in Term Neonates
This study aims to evaluate the effectiveness of adjunctive oral Bifidobacterium animalis subsp. lactis in term neonates with indirect hyperbilirubinemia receiving phototherapy.
- Trial name
- NCT07773012
- Testing
- Bifidobacterium animalis subsp. lactis, Standard Phototherapy
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Can Tho University of Medicine and Pharmacy
Neonatal Jaundice
Aluminium Foil as an Adjuvant to Phototherapy for Pathological Unconjugated Hyperbilirubinaemia in Full Term Infants
prospective single center pilot randomized open label clinical trial, conducted at the Neonatal care unit of Mansoura University Children's To assess the efficacy and safety of aluminum foil use in combination with phototherapy…
- Trial name
- NCT04433923
- Testing
- Phototherapy with aluminum foil, Phototherapy without aluminum foil
- Sponsor
- Mansoura University
Jaundice
Value of Transcutaneous Bilirubin Devices
The goal of this observational study is to compare the value of transcutaneous bilirubin devices versus serum bilirubin in jaundiced neonates
- Trial name
- NCT06232174
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Physiological Neonatal Jaundice, Physiological Hyperbilirubinaemia
Comparison of Effects of Fenofibrate Adjuvant Therapy Versus Conventional Phototherapy in Neonatal Jaundice.
Neonatal jaundice has significant importance in neonatal morbidity and mortality world-wide. Though phototherapy has a relentless use in neonatal jaundice, its cumbersome side effects and the physical separation of baby from the…
- Trial name
- NCT06346743
- Testing
- Fenofibrate, Phototherapy
- Where
- Pakistan
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Muhammad Zark
Neonatal Jaundice
Evaluation of a Smartphone-based Screening Tool for Neonatal Jaundice in a Ugandan Population
The general objective of this study is to evaluate the accuracy of a novel smartphone application that estimates bilirubin levels in newborns at HICH Mbarara.
- Trial name
- NCT05365399
- Testing
- smartphone-based screening tool for neonatal jaundice
- Where
- Uganda
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Picterus AS
Neonatal Hyperbilirubinemia
MRA and ABR as Early Predictors of Bilirubin-Induced Neurologic Dysfunction in Full-term Jaundiced Neonates
The aim of the research was to define the role of MRS and ABR as early predictors of bilirubin-induced neurologic dysfunction (BIND) in full-term neonates who required intervention (phototherapy or exchange transfusion).
- Trial name
- NCT06018012
- Testing
- MRS and ABR
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Tanta University
Neonatal Jaundice
Clinical Validation of the Screening Tool Picterus JP Using Different Smartphones
The overall aim of this study is to verify the quality of our internal developed camera validation systems and allow the use of Picterus JP on all smartphones.
- Trial name
- allphones (NCT05955144)
- Testing
- Picterus JP
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Picterus AS