Clinical trials: Keloid Scars
Keloid
Retrospective Study of Keloid Disorder
Purpose of this retrospective study is to review and analyze the information and data that has been already been generated during the course of routine practice of medicine by the investigators from 2007 up until Sept 1, 2016…
- Trial name
- NCT02923596
- Testing
- History of prior Surgery, History of Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Tirgan, Michael H., M.D.
Keloid
Epidemiology Study of Keloid
Although keloid is a very common condition; there are no statistics as to its true incidence and prevalence, neither in United States, nor elsewhere in the world.
- Trial name
- NCT01423383
- Where
- United States
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Tirgan, Michael H., M.D.
Scleroderma, Keloids
UVA1 Light for Treatment of Scleroderma and Similar Conditions
The purpose of this investigation is to evaluate the effectiveness of an investigational device which is similar in appearance to a "tanning bed" but which emits ultraviolet irradiation of a specific wavelength known as UVA1.
- Conditions
- Scleroderma, Keloids, Other Fibrosing Conditions
- Trial name
- NCT00476801
- Testing
- German manufactured UVA1 light emitting device
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Michigan
Acne Keloidalis Nuchae
The Efficacy of Laser Assisted Hair Removal in the Treatment of Acne Keloidalis Nuchae; a Pilot Study
Laser causes elimination and miniaturization of hair shafts that are the principal contributor to inflammation in Acne Keloidalis Nuchae (AKN).
- Trial name
- NCT01548898
- Testing
- Nd-YAG laser
- Volunteers
- 16 people
- Sponsor
- Cairo University
Keloid, Keloid Scar Following Surgery
Post-Surgical Injection With Triamcinolone Versus Triamcinolone/Fluorouracil in Treatment of Keloids
There have been many modalities utilized in the treatment of keloids of the head and neck, however none have been universally successful.
- Trial name
- NCT04710719
- Testing
- Triamcinolone Injection, Triamcinolone Injection and 5-fluorouracil injection
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Our Lady of the Lake Hospital
Keloids, Keloids Scars
A Prospective Observational Clinical Study on Exploring the Value of Surgical Excision Combined With 32P Application in the Treatment of Keloids and the Factors Affecting the Prognosis of Combined Therapy
Keloids are non-cancerous (benign) growths on the skin. They form after an injury, when the skin makes too much connective tissue that thickens and hardens. These keloids cause big problems for people.
- Trial name
- NCT07413497
- Volunteers
- 401 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cicatrix, Hypertrophic, Keloid
Influence of a Silicone Gel (Dermatix®) on Thoracic Scar Formation After Harvesting of Autologous Rib Cartilage
So far the evaluation of scar treatment was based on subjective criteria. The patient groups were divided into treated versus non-treated. In this study we use patients undergoing ear reconstruction with autologous rib cartilage.
- Trial name
- NCT00565552
- Testing
- Silicone gel (Dermatix®)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University Hospital Schleswig-Holstein
Keloid
A Clinical Study on the Safety and Efficacy of Wide-Band Ultrasound Combined With Traditional Chinese Medicine Preparations in the Prevention and Treatment of Keloids
The prevention and treatment of patients with multiple keloids throughout the body are extremely challenging. Keloids are highly resistant, refractory, and prone to recurrence, and are thus known as the "cancer that does not…
- Trial name
- WBUS +TCM (NCT07679243)
- Testing
- Wide-Band Ultrasound, traditional Chinese medicine
- Volunteers
- 120 people
- Sponsor
- Fujian Medical University Union Hospital
Keloid
Keloid Tissue Bank
Much progress in treatment of various tumors has been made in the laboratory and the results have been brought back to the patients, i.e. from bench to bedside.
- Trial name
- NCT01425437
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Tirgan, Michael H., M.D.
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Keloid and Hypertrophic Scars
Polidocanol 1% and Steroid in Keloids and Hypertrophic Scars
we will inject intralesional polidocanol 1% in keloids and hypertrophic scars to decrease vascularity and decrease size of lesion compared to intralesional steroid as standard treatment line
- Trial name
- NCT07606391
- Testing
- Group 1 (polidocanol 1% group):, Group 2 (Triamcinolone acetonide group):, Group 3 (combined Triamcinolone acetonide and polidocanol 1% group):
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Sohag University
Keloid
High Dose Rate Brachytherapy for Treatment of Keloids
This prospective study evaluates the outcome of surgical excision with adjuvant high-dose-rate brachytherapy for the treatment of recalcitrant keloids. Main outcomes are recurrence rate, scar quality and physical complaints.
- Trial name
- NCT02005055
- Testing
- Surgical excision with adjuvant high-dose-rate brachytherapy
- Where
- Netherlands
- Volunteers
- 43 people
- Sponsor
- Amsterdam UMC, location VUmc
Fibrosis, Scarring
High Fluence Light Emitting Diode-Red Light (LED-RL) in Human Skin
The goal of this study is to establish the safety of high fluence LED-RL from 160 J/cm2 up to 640 J/cm2 in healthy subjects. The hypothesis is that high fluence LED-RL phototherapy is safe in human skin.
- Conditions
- Fibrosis, Scarring, Scar, Wounds
- Trial name
- NCT02630303
- Testing
- LED-RL Phototherapy, Mock Therapy
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jared Jagdeo, MD, MS
Keloid, Scleroderma
UVA1 Light for Scleroderma and Similar Conditions
The purpose of this investigation is to evaluate the effectiveness of high-dose UVA1 irradiation in the treatment of fibrosing conditions of the skin, e.g., keloid (a thick scar from growth of fibrous tissue), scleroderma…
- Conditions
- Keloid, Scleroderma, Scars, Granuloma Annulare
- Trial name
- NCT00476697
- Testing
- German manufactured UVA1 emitting light system
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Keloid
Study of Psycho-Social Impact of Keloid
Despite their benign nature, keloids may constitute a severe aesthetic, and in some cases, functional problem which translates to various repercussions on person's quality of life, including much stress and insecurities.
- Trial name
- NCT01478243
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Tirgan, Michael H., M.D.
Keloid Scars
Comparison of Intralesional Triamcinolone Versus Verapamil for Keloid Treatment
This study aims to compare the efficacy of intralesional triamcinolone and verapamil in patients presenting with keloid at our local setting.
- Trial name
- NCT06897969
- Testing
- Triamcinolone Acetonide 1 ml of 40 mg/mL suspension, Verapamil Injection
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Nishtar Medical University
Keloid, Cicatrix, Hypertrophic
Prospective Evaluation of the Use of Intralesional Cryotherapy for Treatment of Keloid and Hypertrophic Scars
This prospective evaluation studies the effectiveness of IL cryotherapy in treating keloids and hypertrophic scars in a large population of mixed Fitzpatrick skin types.
- Trial name
- NCT01994616
- Testing
- Intralesional cryotherapy
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Amsterdam UMC, location VUmc
Keloids Scars
The Efficacy of Intralesional Bleomycin as Compared to 5-Flourouracil (5-FU) and Triamcinolone Acetonide (TAC) for the Treatment of Keloids: A Randomized Control Trial.
The goal of this clinical trial is to learn if drug bleomycin intralesionally is beneficial than intralesional 5FU and Triamcinolone Acetonide in treating Keloids.
- Trial name
- NCT07201766
- Testing
- intralesional bleomycin, 5-flourouracil and triamcinolone acetonide
- Where
- Pakistan
- Volunteers
- 104 people
- Sponsor
- King Edward Medical University
Scar Keloid
Intralesional Triamcinolone Acetonide and Its Combination With 5-fluorouracil in Keloids and Hypertrophic Scars
Summary: Keloids and hypertrophic scars are benign fibrous growth, differing mainly by overgrowth beyond the initial defect in keloid whereas hypertrophic scar is confined to initial lesion and tends to regress over the years.
- Trial name
- NCT04812626
- Testing
- 5-Fluorouracil
- Where
- Nepal
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- B.P. Koirala Institute of Health Sciences
Keloid
Genetic Analysis of Familial Keloids
The purpose of this study is to identify the gene or genes responsible for keloid formation. Keloids are raised scars on the skin that form after a minor injury.
- Trial name
- NCT00008502
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)