Clinical trials: Kidney Failure, Acute
Acute Kidney Injury
Acute Kidney Injury in Patients on Dapagliflozin and Other Antidiabetic Medications
To compare, by insulin use at the index date, the incidence of hospitalization for acute kidney injury (AKI) among patients with type 2 diabetes mellitus who are new users of dapagliflozin with those who are new users of…
- Trial name
- NCT02695082
- Where
- 3 sites in United States, United Kingdom
- Volunteers
- 539,310 people
- Sponsor
- AstraZeneca
Renal Failure Acute Chronic
Efficacy and Tolerability of the APD Treatment in PAED Patients
The Silencia PD (peritoneal dialysis) cycler offers a pediatric (PAED) mode with advanced features such as Time and Volume Optimization (TAVO), supporting precise and individualized treatment.
- Trial name
- SilenciaPAED (NCT07004907)
- Testing
- Treatment with the pedriatic mode of the APD cycler
- Volunteers
- 13 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Acute Kidney Injury, Covid19
Renal Involvement in Hospitalized Children With COVID-19
Covid-19 is an important human and animal pathogen, it mostly causes respiratory and gastrointestinal symptoms. Clinical features range from a common cold to severe diseases such as severe acute respiratory distress syndrome…
- Conditions
- Acute Kidney Injury, Covid19, Renal Dysfunction, Coronavirus Infection
- Trial name
- RIHCC (NCT04788394)
- Testing
- data review, data comparing
- Where
- Qatar
- Volunteers
- 400 people
- Sponsor
- Hamad Medical Corporation
Congenital Cardiac Defect, Acute Renal Injury
Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery
Blood transfusion strategies in cardiac surgery are a research topic that has been studied more for adults. There is not enough data on this subject for children in studies.
- Conditions
- Congenital Cardiac Defect, Acute Renal Injury, Blood Transfusion Complication
- Trial name
- NCT06889272
- Testing
- blood transfusion
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people
- Sponsor
- Hacettepe University
Acute Kidney Injury
Cost-effectiveness Analyses for the Prevention of Acute Kidney Injury in Patients Undergoing Cardiac Surgery in the UK
Multi-centre retrospective analysis of prospectively collected data with propensity matched scoring groups (AKI v/s non-AKI). Data collection from databases (or their equivalent): PATS Dendrite, Electronic Medical Records, TD-web…
- Trial name
- Cost-AKI (NCT07108634)
- Testing
- RenalGuard Therapy
- Where
- United Kingdom
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Acute Kidney Injury, Congenital Heart Disease
Acute Kidney Injury After Cardiac Surgery on CPB
The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne…
- Conditions
- Acute Kidney Injury, Congenital Heart Disease, Surgery, CBP
- Trial name
- NCT03513718
- Where
- Switzerland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Acute Kidney Injury, Mechanical Ventilation
Biomarker and Renal Angina Validation to Assess Heart-Kidney Outcomes After Amino Acid Therapy
The goal of the BRAVE-HEART study is to learn if an amino acid infusion can reduce the risk of developing acute kidney injury after cardiac surgery in children. The main questions it aims to answer are: 1.
- Trial name
- BRAVE-HEART (NCT07212595)
- Testing
- Amino Acid infusion, Lactated ringers solution
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana Fuhrman
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention
As a single center, retrospective observation study in Guangdong Institute of Cardiovascular Diseases, this study included the main study population of patients who underwent coronary angiography and / or coronary intervention…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT04407936
- Where
- China
- Volunteers
- 88,938 people
- Sponsor
- Guangdong Provincial People's Hospital
Acute Kidney Injury
Prospective Validation of AKI Prediction
The purpose of this prospective observational study is to implement, deploy, and quantify accuracy of an existing Pediatric Early AKI Risk Score algorithm.
- Trial name
- NCT06804200
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Adam C Dziorny
Acute Kidney Injury
Study of the Incidence and Prognosis of Intrahospital Acute Kidney Injury
The goal of this observational study is to investigate the epidemiology of acute kidney injury in hospitalized patients. The main question it aims to answer is: how frequent is the development of acute kidney injury in patients…
- Trial name
- SIPARIO-1 (NCT06697730)
- Where
- Italy
- Volunteers
- 43,000 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Kidney Injury
Acute Kidney Injury in Poly Trauma Patients
The aim of this study is to identify the incidence and the factors associated with acute kidney injury in adult poly trauma patients
- Trial name
- NCT06108765
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Kidney Injury
European Registry of Dialysis Treatment of Pediatric Acute Kidney Injury (AKI)
Acute kidney injury (AKI) is a frequent clinical condition in hospitalized, in particular, in critically ill children. Moreover, AKI is an independent predictor of mortality.
- Trial name
- EurAKID (NCT02960867)
- Where
- Italy
- Volunteers
- 1,892 people
- Sponsor
- Mariella Enoc
Surgery--Complications, Cardiac Valve Disease
Prevention of Acute Kidney Injury by N-Acetylcystein in Patients Undergone Cardiac Valve Replacement
This is a randomized clinical trial, double-blind, placebo-controlled study with the goal to assess the influence of using N-AcetylCysteyn (NAC) for prevention of AKI (Acute Kidney Injury) in post operatory of valve replacement…
- Conditions
- Surgery--Complications, Cardiac Valve Disease, Acute Kidney Injury, Oxygen Radical Damage
- Trial name
- NCT03440268
- Testing
- N Acetyl Cysteine
- Where
- Brazil
- Volunteers
- 154 people
- Sponsor
- University of Sao Paulo General Hospital
Critical Illness, Acute Kidney Failure
Implementation of CRRT KPI Reports to Standardize and Improve the Quality of CRRT Delivery in Alberta "QUALITY CRRT"
Acute kidney replacement therapy (i.e., dialysis) is used in 6-10% of patients admitted to intensive care units (ICUs). The amount of acute kidney replacement therapy use has increased in Canadian ICUs over the last several…
- Trial name
- QUALITY-CRRT (NCT04221932)
- Testing
- CRRT KPI Reports
- Where
- 14 sites in Canada
- Volunteers
- 945 people
- Sponsor
- University of Alberta
Acute Kidney Injury
Acute Kidney Injury in Major Abdominal Surgery: Retrospective Study of 501 Patients
Retrospective study that aims to examine the presence of acute kidney injury (AKI) during major abdominal surgery, non- cardiac surgery. Using clinical and biochemical data in order to establish AKI frequency and risk factors.
- Trial name
- NCT04130347
- Volunteers
- 499 people
- Sponsor
- Uppsala University
Cystic Fibrosis (CF), Chronic Kidney Disease(CKD)
Kidney Function in People With Cystic Fibrosis in the Era of HEMT
The purpose of this study is to find out what causes kidney disease in people with CF. The investigators will study biomarkers in the blood and urine that can either predict who is at risk or detect kidney damage early before it…
- Conditions
- Cystic Fibrosis (CF), Chronic Kidney Disease(CKD), Acute Kidney Injury
- Trial name
- NCT06595420
- Where
- 3 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Congenital Heart Disease, Cardiopulmonary Bypass
Seattle Cardiorenal Remote Ischemic Preconditioning Trial
Remote Ischemic Preconditioning (RIPC) is a treatment that may be associated with improved outcomes after cardiac surgery. It can be elicited noninvasively by using a tourniquet to elicit transient ischemia over a lower…
- Conditions
- Congenital Heart Disease, Cardiopulmonary Bypass, Myocardial Injury, Acute Kidney Injury
- Trial name
- SCRIPT (NCT01260259)
- Testing
- RIPC, Control
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Seattle Children's Hospital
Acute Renal Failure (ARF), Acute Kidney Injury (AKI)
Retrospective Analysis of Prismaflex HF20 Set Versus ppCRRT Registry
A retrospective multicenter, observational design intended to capture data on pediatrics (weighing between 8 - 20 kg) who underwent continuous renal replacement therapy (CRRT) using the HF20 set.
- Conditions
- Acute Renal Failure (ARF), Acute Kidney Injury (AKI), Fluid Overload in Dialysis Patients
- Trial name
- NCT06633029
- Testing
- Prismaflex HF20
- Where
- 5 sites in United States
- Volunteers
- 59 people
- Sponsor
- Vantive Health LLC
Cancer
Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant
RATIONALE: Giving donor natural killer cells to patients who have undergone donor bone marrow transplant may make the transplant work better and keep cancer cells from coming back.
- Trial name
- NCT00569283
- Testing
- therapeutic allogeneic lymphocytes
- Where
- 2 sites in South Korea
- Volunteers
- 18 people
- Sponsor
- Asan Medical Center
Acute Kidney Injury
Remote Ischemic Preconditioning to Prevent Contrast Nephropathy
Contrast-medium induced nephropathy (CIN) is a frequent and devastating complication of coronary angiography, occurring in 10-50% of cases.
- Trial name
- RIPC-CIN (NCT02674451)
- Testing
- Remote ischemic preconditioning
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Johns Hopkins University