Clinical trials: Kidney Injury
Congenital Cardiac Defect, Acute Renal Injury
Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery
Blood transfusion strategies in cardiac surgery are a research topic that has been studied more for adults. There is not enough data on this subject for children in studies.
- Conditions
- Congenital Cardiac Defect, Acute Renal Injury, Blood Transfusion Complication
- Trial name
- NCT06889272
- Testing
- blood transfusion
- Where
- Turkey (Türkiye)
- Volunteers
- 205 people
- Sponsor
- Hacettepe University
Chronic Kidney Diseases, COVID-19 Infection
COVID-19 Among Children With Chronic Renal Diseases in Qatar
Coronavirus disease 2019 is a novel viral disease caused by the Severe Acute Respiratory Syndrome Coronavirus 2 virus. The original cases occurred in Wuhan, China, in December 2019 and rapidly spread to other areas worldwide…
- Conditions
- Chronic Kidney Diseases, COVID-19 Infection, Acute Kidney Injury, Chronic Renal Failure in Children
- Trial name
- CCCRDQ (NCT05275595)
- Testing
- Medical records review
- Where
- Qatar
- Volunteers
- 1,300 people
- Sponsor
- Hamad Medical Corporation
Acute Kidney Injury
Guidance of Ultrasound in Intensive Care to Direct Euvolemia
The purpose of this study is to assess the effectiveness of routine ultrasound assessments of volume status and fluid responsiveness for goal-directed therapy (GDT)-based fluid resuscitation in reducing acute kidney injury (AKI)…
- Trial name
- GUIDE (NCT03938038)
- Testing
- Serial ultrasound assessments for GDT, Usual care
- Where
- United States
- Volunteers
- 415 people
- Sponsor
- The University of Texas Health Science Center, Houston
Kidney Injury
Acute Kidney Injury in Poly Trauma Patients
The aim of this study is to identify the incidence and the factors associated with acute kidney injury in adult poly trauma patients
- Trial name
- NCT06108765
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Kidney Injury, Chronic Kidney Disease
Severe Sepsis in Children - IMPRESS-C
Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease, Hypertension
- Trial name
- IMPRESS-C (NCT02598674)
- Testing
- Iodohippurate, 24 hour ambulatory Blood Pressure, Peripheral Arterial Tonometry
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
AKI in Diabetic Ketoacidosis
Prevalence of Acute Kidney Injury in Patients With Diabetic Ketoacidosis
prevalence of acute kidney injury in patients with diabetic ketoacidosis
- Trial name
- NCT05508490
- Testing
- renal chemistry, serum electrolyte,
- Volunteers
- 100 people
- Sponsor
- Assiut University
Renal Insufficiency, Acute
Determination of the "Tissue Transit Time" (TTT)
Determination of Tissue Transit Time (TTT) as a parameter with high prognostic value to predict the functional course of the differential renal function and the development of the differential renal function after pyeloplasty
- Trial name
- NCT03311256
- Testing
- Tissue Transit Time
- Where
- 9 sites in Germany, Switzerland
- Volunteers
- 119 people
- Sponsor
- University Hospital Tuebingen
Acute Kidney Injury, Renal Insufficiency
Timing of Coronary Angiography, Cardiac Surgery, and Adverse Renal and Cardiac Events (MARCE)
1. To examine two main predictor variables independently and then jointly in stratified and multivariate analyses for the outcomes of CSA-AKI, MARCE, need for RRT, and inpatient mortality, and the composite, as well as the…
- Trial name
- MARCE (NCT02332070)
- Testing
- cardiac surgery
- Where
- United States
- Volunteers
- 965 people
- Sponsor
- Baylor Research Institute
Acute Kidney Injury
Effects of Oral Protein Load on Kidney Function in Patients Undergoing Cardiac Surgery
Acute kidney injury (AKI) occurs in approximately one-third of patients undergoing cardiac surgery (CS), and represents one of the most significant negative predictors of patient outcome in this population.
- Trial name
- NCT03102541
- Testing
- None intervention
- Volunteers
- 214 people
- Sponsor
- University of Giessen
AKI in Cirrhosis
Predictors of Mortality in Cirrhotic Patients With Acute Kidney Injury
Acute kidney injury (AKI) is a common and severe complication in patients with liver cirrhosis, significantly increasing the risk of short-term mortality.
- Trial name
- NCT07797114
- Volunteers
- 100 people
- Sponsor
- Assiut University
Acute Kidney Injury
The Effect of the Hydroxyethyl Starch on Kidney Injury in Pediatric Cardiac Surgery
The investigator will evaluate the influence of colloid administration on postoperative acute kidney injury in pediatric patients undergoing cardiac surgery under cardiopulmonary bypass.
- Trial name
- NCT02599155
- Testing
- Crystalloid, Colloid
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Diabetes Mellitius
Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 As Biomarkers of AKI in Children With DKA
Type 1 diabetes mellitus (T1DM) is a common, chronic, metabolic disorder that has significant consequences for physical and emotional development .
- Trial name
- AKI (NCT06032325)
- Testing
- Neutrophil Gelatinase and Kidney Injury Molecule-1
- Volunteers
- 48 people
- Sponsor
- Assiut University
End-Stage Renal Disease, Kidney Failure
Eculizumab for Prevention and Treatment of Kidney Graft Reperfusion Injury
Study of eculizumab ability to correct the reperfusion injury of the kidney allograft.
- Conditions
- End-Stage Renal Disease, Kidney Failure, Graft Reperfusion Injury
- Trial name
- NCT01756508
- Testing
- eculizumab
- Where
- Russia
- Volunteers
- 57 people
- Sponsor
- Russian Academy of Medical Sciences
Acute Kidney Injury, Hypoxic-Ischemic Encephalopathy
PK and Safety of Caffeine in Neonates With Hypoxic Ischemic Encephalopathy Receiving Therapeutic Hypothermia
A phase 1 study investigating the tolerability and pharmacokinetics of caffeine citrate in neonates with hypoxic ischemic encephalopathy receiving therapeutic hypothermia.
- Conditions
- Acute Kidney Injury, Hypoxic-Ischemic Encephalopathy, Caffeine
- Trial name
- NCT05295784
- Testing
- Caffeine citrate
- Where
- 2 sites in United States
- Sponsor
- University of Arkansas
Urinary Tract Infections
Evaluation of the Plasmatic NGAL as a Predictive Marker of Renal Injury in Children With Urinary Infection. (Perf-NGAL-IU)
Urinary infections in children is very common. Delay in the diagnosis may be followed by complications. Pyelonephritis is a febrile urinary infection with a renal injury.
- Trial name
- Perf-NGAL-IU (NCT04191785)
- Testing
- plasmatic NGAl and MRI
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Lenval
Acute Kidney Injury, Renal Replacement Therapy
Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric AKI
This study follows a group of patients admitted to the PICU who are identified as being at risk for developing acute kidney injury.
- Conditions
- Acute Kidney Injury, Renal Replacement Therapy, Pediatric Intensive Care Units
- Trial name
- Taking Focus 2 (NCT03541785)
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Renal Failure
Assessing the Impact of Two Methods of Continuous Veno-venous Hemodiafiltration on Time Nursing Work in Intensive Care
The prevalence of acute renal failure in intensive care is estimated at between 5 and 20% depending on diagnostic criteria retained. And half of patients require the use of hemodialysis.
- Trial name
- NCT00993733
- Testing
- Continuous veno-venous haemodiafiltration
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Neonatal Acute Renal Failure in Preterm
Nephronic Reduction After Neonatal Acute Renal Failure in Preterm
The aim of this study is to evaluate the signs of nephronic reduction in preterm infants who have presented neonatal acute renal failure.
- Trial name
- IRENEO (NCT01785238)
- Testing
- renal echography, Blood sampling, collection of an urine sample
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
To Explore the Influence of CRRT Nursing Team Management Plan on the Prognosis of SAKI Patients
Impact of the CRRT Management Protocol on Prognostic Outcome in Patients With Septic Acute Kidney Injury
The implementation of CRRT nursing team management program in the treatment of SAKI can significantly reduce the incidence of adverse events and complications in CRRT nursing, which has a positive role in improving the success…
- Trial name
- NCT06083285
- Testing
- Implement the CRRT specialist nursing group management program on the basis of routine care
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Xinjiang Medical University
Anesthesia, Sedation
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful.
- Conditions
- Anesthesia, Sedation, Monitored Anesthesia Care, Procedure
- Trial name
- MACS (NCT07022951)
- Testing
- Preoperative fasting
- Where
- United States
- Volunteers
- 1,200,000 people
- Sponsor
- Massachusetts General Hospital