Clinical trials: Kidney Neoplasms / Surgery
Fear of Cancer Recurrence, Renal Cell Carcinoma (Kidney Cancer)
Patient-partnered Research in Investigating Fear of Cancer Recurrence in Kidney Cancer
The goal of this observational study is to gather real-world information about Fear of Cancer Recurrence (FCR) following surgery in patients with renal cell carcinoma (RCC) and their partners/spouses by 1) establishing a panel…
- Trial name
- PP-RECURK (NCT07234656)
- Testing
- Phase 1: Establishment of a patient-partner panel, Phase 2: Feasibility testing of FCR questions, mode of administration and timing for investigating Fear of Cancer Recurrence
- Where
- 3 sites in Denmark
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Brigitta Rasmussen Villumsen
Kidney Cancer
Studying Tumor Tissue Samples From Patients Who Have Undergone Surgery for Localized Kidney Cancer
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00908739
- Testing
- gene expression analysis, immunohistochemistry staining method, laboratory biomarker analysis
- Sponsor
- Case Comprehensive Cancer Center
Childhood Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma
Combination Chemotherapy, Radiation Therapy, and/or Surgery in Treating Patients With High-Risk Kidney Tumors
This phase II trial is studying how well combination chemotherapy, radiation therapy, and/or surgery work in treating patients with high-risk kidney tumors.
- Conditions
- Childhood Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma, Clear Cell Sarcoma of the Kidney, Papillary Renal Cell Carcinoma
- Trial name
- NCT00335556
- Testing
- Doxorubicin Hydrochloride, Irinotecan Hydrochloride, Conventional Surgery
- Where
- 187 sites in United States, Australia and 3 more
- Volunteers
- 291 people
- Sponsor
- Children's Oncology Group
Pediatric Disorder, Hydronephrosis in Children
Effect of Concomitant Bladder Neck Incision and Urethral Valve Ablation on Surgical Re-intervention Rate for Patients With Posterior Urethral Valve
To determine the short-term effects of concurrent valve ablation and bladder neck incision on re-intervention rate for patients with posterior urethral valve.
- Conditions
- Pediatric Disorder, Hydronephrosis in Children, Hydronephrosis, Secondary, Hydronephrosis Congenital
- Trial name
- NCT05087537
- Testing
- Valve ablation, Valve ablation and bladder neck incision
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Mansoura University
Nephroblastoma With Vena Cava Thrombosis
Vascular Thrombus Involvement in Nephroblastoma
Nephroblastoma (Wilms tumor) is the most common kidney tumor in children. It is a malignant embryonic tumor with a good prognosis with more than 85% long-term survival with appropriate chemotherapy, surgery (which most often…
- Trial name
- VIN (NCT05195411)
- Where
- 2 sites in France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Cancer
Gene Expression in Normal Tissue and Tumor Tissue From Patients Who Have Undergone Surgery For Kidney Cancer
RATIONALE: Studying the genes and proteins expressed in tissue samples from patients with cancer may help doctors identify biomarkers related to cancer.
- Trial name
- NCT00899860
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Venous Thromboembolism, Pulmonary Embolism
Epidemiology of Venous Thromboembolism
More than 5 years ago the DVT FREE Registry was conceived. Its database consists of 5,451 ultrasound-confirmed DVT patients from 183 institutions.
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Cancer, Deep Vein Thrombosis
- Trial name
- NCT00456196
- Where
- United States
- Volunteers
- 5,451 people
- Sponsor
- Brigham and Women's Hospital
Renal Cell Carcinoma
Pre-Surgical Sutent in Renal Cell Carcinoma (RCC)
The goal of this clinical research study is to learn if Sutent® (sunitinib malate), given before surgery, can help control renal cell carcinoma. The safety of sunitinib malate will also be studied.
- Trial name
- NCT00715442
- Testing
- Sunitinib, Nephrectomy
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- M.D. Anderson Cancer Center
Renal Cell Carcinoma, Three-Dimensional
3D-biomodels for Surgical Planning in Patients With Renal Cancer and Vascular Involvement
Objectives: Apply 3D- printed biomodels in patients with renal cancer (RCa) and vascular involvement (VTT) to: (1) improve surgical planning, (2) upgrade surgical results, (3) facilitate communication with patients, (4) serve as…
- Conditions
- Renal Cell Carcinoma, Three-Dimensional, Venous Thromboses
- Trial name
- 3DUrologia (NCT03738488)
- Testing
- 3D printing + images, Images
- Where
- 2 sites in Spain
- Volunteers
- 10 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Pediatric Renal Tumor, Metastatic Osteosarcoma
Indo-cyanine Green (ICG) in Paediatric Oncology MIS
Indo-cyanine green (ICG) is a dye that has been used for a variety of adult and paediatric uses since 1956. Over the past few years, near infrared (NIRF) technology has been developed which allow is use as a fluorescence agent…
- Conditions
- Pediatric Renal Tumor, Metastatic Osteosarcoma, Metastatic Ewing Sarcoma, Pulmonary Metastasis
- Trial name
- NCT04854018
- Testing
- Indocyanine green
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Birmingham Women's and Children's NHS Foundation Trust
Vascular Postoperative Complications, Urological System Complication of Procedure
Fibrin Based Adhesive for the Prevention of Surgical Complications in the Kidney Transplantation
Globally there have been about 45,000 kidney transplants last year. Currently, the overall survival of renal transplant receptors is 95% in the first year and 85% at 5 years.
- Conditions
- Vascular Postoperative Complications, Urological System Complication of Procedure, Lymphocele, Postoperative Infection
- Trial name
- NCT01631448
- Testing
- Fibrin Glue
- Where
- 2 sites in Mexico
- Volunteers
- 152 people
- Sponsor
- Alejandro Gonzalez-Ojeda
Kidney Cancer
Chemotherapy Before and After Surgery in Treating Children With Wilm's Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving combination chemotherapy before surgery may shrink the tumor so it can be removed during surgery.
- Trial name
- NCT00047138
- Testing
- dactinomycin, carboplatin, cyclophosphamide
- Where
- 4 sites in France, Germany and 2 more
- Volunteers
- 350 people
- Sponsor
- University of Leicester
Pediatric Cancer, Neuroblastoma
Biomarkers of Resiliency In Childhood Cancer Surgery
This observational study is to better understand how children and their families recover after the stress of major surgery for cancer so that investigators can create ways to improve resilience during recovery.
- Conditions
- Pediatric Cancer, Neuroblastoma, Sarcoma, Wilms Tumor and Other Childhood Kidney Tumors
- Trial name
- BRICCS (NCT06674811)
- Testing
- Wearing Smartwatch, Patient Report Outcomes, Blood Draw
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Endometrial Cancer, Kidney Cancer
Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Conditions
- Endometrial Cancer, Kidney Cancer, Metastatic Cancer, Ovarian Cancer
- Trial name
- NCT00002764
- Testing
- filgrastim, doxorubicin hydrochloride, ifosfamide
- Where
- Sweden
- Volunteers
- 340 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Renal Cell Carcinoma, Metastases, Neoplasm
Surgical Treatment of Pancreatic RCC Metastases
Data from 26 patients undergoing resection of Pancreatic Metastases and extra-Pancreatic Metastases from RCC were retrospectively analysed.
- Trial name
- NCT03670992
- Testing
- duodenal-pancreatectomy
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Azienda Policlinico Umberto I
Nonfunctional Kidney, Renal Cancer
Single-layer Robot-assisted Transperitoneal Retroperitoneal Tubeless Radical Nephrectomy
To investigate the effect of single-layer robot-assisted retroperitoneal approach for radical nephrectomy without tubularization
- Trial name
- NCT06565598
- Testing
- Single-layer robot-assisted transperitoneal retroperitoneal tubeless radical nephrectomy
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The First People's Hospital of Xiushui
Kidney Cancer
Chemotherapy Plus Surgery in Treating Children at Risk of or With Stage I Wilms' Tumor
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of chemotherapy is more effective for stage I Wilms' tumor.
- Trial name
- NCT00003804
- Testing
- dactinomycin, vincristine sulfate, conventional surgery
- Where
- 44 sites in Belgium, Croatia and 13 more
- Volunteers
- 350 people
- Sponsor
- University of Leicester
Kidney Cancer
Chemotherapy Followed by Surgery and Radiation Therapy With or Without Stem Cell Transplant in Treating Patients With Relapsed or Refractory Wilms' Tumor or Clear Cell Sarcoma of the Kidney
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplant may allow the doctor to give higher doses of…
- Trial name
- NCT00025103
- Testing
- dactinomycin, carboplatin, cyclophosphamide
- Where
- 21 sites in Ireland, United Kingdom
- Volunteers
- 75 people
- Sponsor
- Children's Cancer and Leukaemia Group
Solid Tumor
A Study of OMX-0407 in Patients With Previously Treated Solid Tumours That Can't be Removed Surgically
The main purpose of the dose escalation phase of the study is to determine the safety of different doses of OMX-0407. The dose expansion (phase Ib) part of the study will evaluate efficacy, safety and tolerability at a dose…
- Trial name
- NCT05826600
- Testing
- OMX-0407
- Where
- 24 sites in Belgium, France and 1 more
- Volunteers
- 68 people
- Sponsor
- iOmx Therapeutics AG
Kidney Cancer
Interleukin-2 in Treating Patients With Stage III or Stage IV Kidney Cancer That Has Been Removed With Surgery
RATIONALE: Interleukin-2 may stimulate a person's white blood cells to kill kidney cancer cells. PURPOSE: Phase II trial to study the effectiveness of interleukin-2 in treating patients with stage III or stage IV kidney cancer…
- Trial name
- NCT00003604
- Testing
- aldesleukin
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Cancer Biotherapy Research Group