Clinical trials: Knee Injuries
Cartilage Disease
Non-interventional Study in Pediatric Patients Treated With NOVOCART Inject in the Knee
The study is a prospective, multicenter, single-arm non-interventional study to evaluate the efficacy, safety and health economics of NOVOCART® Inject in the treatment of cartilage defects of the knee in pediatric patients with…
- Trial name
- NINJA (NCT05391841)
- Testing
- NOVOCART Inject
- Where
- 6 sites in Germany
- Sponsor
- Tetec AG
Ankle Fractures, Knee Fractures
Performance and Safety Follow-up of Bioabsorbable Headless Inion CompressOnTM Screws in the Fixation of Bone Fractures in Ankle, Knee and Elbow of Pediatric and Adolescent Patients
The study in question is a post market clinical follow up (PMCF) study to follow up the safety and performance of bioabsorbable headless compression screw Inion CompressOn in fracture fixation of the ankle, knee and elbow of…
- Conditions
- Ankle Fractures, Knee Fractures, Elbow Fractures
- Trial name
- NCT07473947
- Testing
- Fracture fixation operation
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Inion Oy
Defect of Articular Cartilage, Articular Cartilage Disorder of Knee
the Safety and Efficacy Evaluation of Chondron Compared With Mircrofracture of Knee
The purpose of this study is to evaluate safety and efficacy of Chondron(autologous cultured Chondrocyte) by comparing between Chondron implantation and Microfracture.
- Conditions
- Defect of Articular Cartilage, Articular Cartilage Disorder of Knee, Degeneration; Articular Cartilage, Knee
- Trial name
- NCT02524509
- Where
- South Korea
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
Bridge-Enhanced ACL Restoration (BEAR) is a new procedure being developed to treat patients with ACL injuries. In the BEAR procedure, an implant is placed between the torn ends of the ACL and the patient's own blood is added to…
- Trial name
- NCT03348995
- Testing
- Bridge-Enhanced ACL Restoration (BEAR)
- Where
- 11 sites in United States
- Volunteers
- 250 people
- Sponsor
- Miach Orthopaedics
Knee Injuries
Efficacy and Safety of OMS103HP in Patients Undergoing Autograft Anterior Cruciate Ligament (ACL) Reconstruction
The anterior cruciate ligament (ACL) is an important stabilizer of the knee. Orthopedic surgeons replace the torn ligament during ACL reconstruction surgery.
- Trial name
- NCT00226772
- Testing
- OMS103HP, Vehicle
- Where
- 18 sites in United States, Canada
- Volunteers
- 326 people
- Sponsor
- Omeros Corporation
ACL Tears
BioBrace® Augmentation in Anterior Cruciate Ligament Reconstruction Procedures
This research study will evaluate mid-term clinical safety and performance outcomes of the BioBrace® Reinforced Implant when used to augment a tissue graft during anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT06948591
- Testing
- Anterior cruciate ligament reconstruction with BioBrace® augmentation, Arthroscopic anterior cruciate ligament reconstruction
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- CONMED Corporation
Defect of Articular Cartilage, Osteoarthritis
Comparison of Efficacy and Safety of Microfracture and Modified Microfracture
This study was designed to evaluate the efficacy and safety of a modified microfracture using collagen, and to compare them with those of a simple microfracture to prove the non-inferiority of the modified microfracture using…
- Conditions
- Defect of Articular Cartilage, Osteoarthritis, Traumatic Arthritis
- Trial name
- NCT02539030
- Testing
- Microfracture, CartiFill
- Where
- 12 sites in South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cellontech Co., Ltd.
Anterior Cruciate Ligament Injuries, Posterior Cruciate Ligament Tear
Interference Screw Mectascrew-C Postmarket Study
An observational prospective study with the aim to analyze the presence at 6 months of a specific composite IS (Medacta Mectascrew C) in the reconstructive treatment of ruptured ACL or PCL by means of an autograft or allograft.
- Trial name
- NCT05791656
- Testing
- Mectascrew-C
- Where
- Switzerland
- Volunteers
- 44 people
- Sponsor
- Medacta International SA
Anterior Cruciate Ligament Injuries
A Prospective Cohort Post Market Registry Evaluating Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)
The purpose of the Bridge Registry is to assess real-world performance of the FDA approved BEAR Implant.
- Trial name
- NCT05398341
- Testing
- The BEAR® Implant
- Where
- 8 sites in United States
- Volunteers
- 300 people
- Sponsor
- Miach Orthopaedics
Dislocated Patella, Torn Medial Patellofemoral Ligament
Repair of Medial Patellofemoral Ligament Compared to Conservative Treatment for First Time Patella Dislocation
Background: The forces involved in a patella dislocation event can cause significant collateral damage involving the articular cartilage of the patella femoral joint.
- Trial name
- NCT02185001
- Testing
- Direct Medial Patellofemoral Ligament (MPFL) Repair, Physical therapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Orthopedic Specialty Institute
Knee Injuries
Efficacy and Safety of OMS103HP in Patients Undergoing Allograft Anterior Cruciate Ligament (ACL) Reconstruction
The anterior cruciate ligament (ACL) is an important stabilizer of the knee. Orthopedic surgeons replace the torn ligament during ACL reconstruction surgery.
- Trial name
- NCT00226759
- Testing
- OMS103HP, Vehicle
- Where
- 20 sites in United States, Canada
- Volunteers
- 321 people
- Sponsor
- Omeros Corporation
ACL Tears
MRI Evaluation of Graft Maturation Following ACL Reconstruction
Post-surgical ACL Graft maturation will be assessed at 4.5, 6, 7.5, 9, 10.5, and 12 months with MRI.
- Trial name
- NCT07046000
- Testing
- MRI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Skye Biologics Holdings, LLC
Anterior Cruciate Ligament Tear
Bridge-Enhanced ACL Repair vs ACL Reconstruction
The goal of this trial is to compare the efficacy of the Bridge-Enhanced Anterior Cruciate Ligament Repair (BEAR™) technique with the current method of treatment for anterior cruciate ligament (ACL) injuries, ACL reconstruction.
- Trial name
- NCT02664545
- Testing
- BEAR Scaffold, Tendon Graft
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Miach Orthopaedics