Clinical trials: Knee Ligament Injury
Patellar Dislocation, Recurrent, Patellar Dislocation
JUPITER 4.0 - Risk Factors for Failure of Isolated Medial Patellofemoral Ligament Reconstruction
The goal of this observational study is to learn about the outcomes of medial patellofemoral ligament (MPFL) reconstruction for the treatment of recurrent patellar instability.
- Conditions
- Patellar Dislocation, Recurrent, Patellar Dislocation, Patellar Instability, Patellofemoral Dislocation
- Trial name
- NCT06883396
- Testing
- Medial Patellofemoral Ligament (MPFL) Reconstruction
- Where
- 16 sites in United States
- Volunteers
- 850 people
- Sponsor
- Hospital for Special Surgery, New York
Anterior Cruciate Ligament Tear
IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions
Injury to the knee during sports participation often involves partial or full detachment of the anterior cruciate ligament (abbreviated as ACL). ACL tears cause pain, swelling and inflammation.
- Trial name
- EASI ACL (NCT02930122)
- Testing
- anakinra (150mg), Saline intraarticularly
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cale Jacobs, PhD
Anterior Cruciate Ligament Injuries
A Reliability and Validity Study of Urdu Version of Lysholm Knee Scoring Scale.
The study will be intended to translate and check if the Urdu Version of Lysholm Knee Scoring Scale is reliable and valid in the Pakistani patients with anterior cruciate ligament injuries.
- Trial name
- NCT05207553
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Injuries, Knee Injuries
Graft Type and Outcomes After ACL Reconstruction in Female Athletes
This prospective multicenter cohort study aims to compare clinical and functional outcomes between hamstring tendon and quadriceps tendon autografts in anterior cruciate ligament (ACL) reconstruction in female athletes.
- Trial name
- LCA-WOMEN (NCT07722104)
- Testing
- Hamstring tendon autograft ACL reconstruction, Quadriceps tendon autograft ACL reconstruction
- Where
- Spain
- Volunteers
- 82 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Ligament Injury, Knee Injuries
Clinical-instrumental Evaluation and Assessment of Return to Sports Activity in Patients Surgically Treated for Isolated "Stener-like" Lesions of the Medial Collateral Ligament (MCL) or in the Context of Multiligament Injuries and Articular Fractures
The knee is a complex joint stabilized by four main ligaments: the anterior and posterior cruciate ligaments and the medial and lateral collateral ligaments.
- Trial name
- STENER_MCL (NCT07174219)
- Where
- Italy
- Volunteers
- 43 people
- Sponsor
- Stefano Zaffagnini
Telerehabilitation, Anterior Cruciate Ligament Injuries
Telerehabilitation for Anterior Cruciate Ligament Reconstruction - TAR Program in Adolescents
Anterior cruciate ligament (ACL) injuries are common in adolescents and its prevalence has increased over the years, especially with more adolescents engaging in physical activities and competitive sports.
- Conditions
- Telerehabilitation, Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament
- Trial name
- TAR (NCT05799235)
- Testing
- Telerehabilitation TAR program using a mobile application, Standard rehabilitation sessions
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- KK Women's and Children's Hospital
Injury of Anterior Cruciate Ligament
Sport Cord Test Following ACL Reconstruction
The primary purpose of this study is to determine the interrater reliability and validity of the Sportcord Test as a measure of physical performance following anterior cruciate ligament (ACL) reconstruction.
- Trial name
- NCT01937403
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- The Hawkins Foundation
Anterior Cruciate Ligament Injury, ACL
Mechanical Perturbation Training for ACL Injury Prevention
A prospective trial will be used to evaluate the efficacy of prophylactic mechanical perturbation training program. 24 female athletes who are regular participants in activities that involve cutting, pivoting, jumping, and…
- Trial name
- NCT03080402
- Testing
- Mechanical Perturbation Training
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Delaware
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
ACL Injury, ACL Augmentation
Augmentation of Partial Anterior Cruciate Ligament Tear: Early Results
Clinical evaluation for the patients with partial ACL tear who had ACL augmentation
- Trial name
- Augmentation (NCT05391672)
- Testing
- we will do ACL augmentation surgery to the patients who have partial ACL tear
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
ACL Injury, Pain
Effect of Biophysical Stimulation on Intraspongious Bone Edema in Anterior Cruciate Ligament Reconstruction
The following study has as main objective to evaluate whether the use of I-ONE® therapy can reduce post-operative pain thanks to the modulation of inflammation in patients with bone bruise on the knee after anterior cruciate…
- Conditions
- ACL Injury, Pain, Magnetic Field Exposure
- Trial name
- NCT04255407
- Testing
- I-ONE® therapy, Anti-inflammatory drug
- Where
- Italy
- Volunteers
- 66 people
- Sponsor
- Istituto Ortopedico Rizzoli
Anterior Cruciate Ligament Injuries
Influence of Proprioceptive Reweighting Ability on Lower-limb Biomechanics During Functional Tasks
Anterior cruciate ligament (ACL) injuries are frequent in handball especially among young players. Recent investigations highlighted the implication of the central nervous system as a potential risk factor for ACL rupture.
- Trial name
- NEURIBIO (NCT04736511)
- Testing
- Star Excursion Balance Test, Single leg Drop Vertical Jump, Unplanned sidestep cutting manoeuvre
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Anterior Cruciate Ligament Injury
Motor Imagery to Facilitate Sensorimotor Relearning After ACL Injury
Anterior cruciate ligament injury is a common issue in sports involving cutting and jumping. Treatment may include surgical intervention followed by physical therapy, or no surgical intervention with the main treatment being…
- Trial name
- MOTIFS (NCT03473821)
- Testing
- MOTIFS
- Where
- Sweden
- Volunteers
- 106 people
- Sponsor
- Lund University
Knee Injury, ACL Injury
Reducing Disparities in Knee Arthroscopy for Adolescents
Hundreds of thousands of youth athletes require surgery for knee injuries annually. The incidence of operative knee injuries has skyrocketed, but surgery can be delayed due to late recognition and barriers, such as insurance…
- Conditions
- Knee Injury, ACL Injury, Meniscus Tear, Hispanic or Latino
- Trial name
- RED KARD (NCT07580625)
- Testing
- Educational program and patient navigator
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Anterior Cruciate Ligament (Acl) Reconstruction
The Psychological Impact of Mindfulness Intervention to Anterior Cruciate Ligament Reconstruction
Anterior cruciate ligament (ACL) reconstruction surgery is a common procedure performed by orthopedic surgeons. Postoperatively, patients often experience pain, muscle tension, and concerns about their ability to return to…
- Trial name
- NCT06382324
- Testing
- mindfulness practice of body scan, listening to light music
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
ACL Injury, ACL - Anterior Cruciate Ligament Rupture
Improving ACL Reconstruction Outcomes: CBPT
The overall objective of this study is to conduct a two-group randomized trial to examine the efficacy of cognitive-behavioral based physical therapy (CBPT) for improving knee function, return to sport, and quality of life…
- Conditions
- ACL Injury, ACL - Anterior Cruciate Ligament Rupture, ACL Sprain, ACL Tear
- Trial name
- NCT03243162
- Testing
- CBPT-ACLR, Education
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Vanderbilt University Medical Center
Anterior Cruciate Ligament Injuries
A Prospective Cohort Post Market Registry Evaluating Outcomes of Bridge-Enhanced ACL Restoration (BEAR®)
The purpose of the Bridge Registry is to assess real-world performance of the FDA approved BEAR Implant.
- Trial name
- NCT05398341
- Testing
- The BEAR® Implant
- Where
- 8 sites in United States
- Volunteers
- 300 people
- Sponsor
- Miach Orthopaedics
Anterior Cruciate Ligament Injuries
Assessment of Anterior Cruciate Ligament (ACL) Degeneratio Mucosa Treatment
Anterior Cruciate Ligament (ACL) Degeneratio Mucosa is a condition resulting from mucoid degeneration of ACL. Exact etiology is unknown, however ACL Degeneratio Mucosa impairs everyday functioning.
- Trial name
- NCT05701579
- Testing
- ACL "decompression"
- Where
- Poland
- Volunteers
- 10 people
- Sponsor
- Artromedical Konrad Malinowski Clinic
ACL Injury, Quadriceps Muscle Atrophy
BFR Therapy After ACL Reconstruction
This study is a prospective, double-blinded, randomized control trial examining the effect of blood flow restriction (BFR) therapy on reducing post-operative quadriceps atrophy in patients undergoing anterior cruciate ligament…
- Trial name
- BFR (NCT03794570)
- Testing
- Blood flow restriction therapy - with Delfi Personalized Tourniquet System
- Where
- United States
- Sponsor
- Steadman Philippon Research Institute