Clinical trials: Knee Pain
Phantom Limb Pain
Comparison of Efficacy of Mirror Therapy vs Mental Imagery in Reduction of Phantom Limb Pain in AKAP
Limb amputation results in many types of pain, including localized pain at the stump and projected pain experienced by the patient in the location where the amputated limb used to be, known as phantom limb pain (PLP).
- Trial name
- NCT06428123
- Testing
- Mirror Therapy on present Lower Limb, Mental Imagery on present Lower Limb
- Where
- 2 sites in Pakistan
- Volunteers
- 24 people
- Sponsor
- Superior University
Anterior Cruciate Ligament Tear
IL-1RA Treatment in Patients With Acute ACL Tear and Painful Effusions
Injury to the knee during sports participation often involves partial or full detachment of the anterior cruciate ligament (abbreviated as ACL). ACL tears cause pain, swelling and inflammation.
- Trial name
- EASI ACL (NCT02930122)
- Testing
- anakinra (150mg), Saline intraarticularly
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Cale Jacobs, PhD
Osteo Arthritis Knee
Post-op Ketamine Study
The purpose of this study is to establish the effect of sub-anesthetic dosing of ketamine with spinal anesthesia during total knee arthroplasty on post-operative pain and narcotic consumption.
- Trial name
- NCT03865550
- Testing
- Isotonic saline, Ketamine Injectable Solution
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Rothman Institute Orthopaedics
Surgery, Pain, Post Operative
Comparing Analgesic Regimen Effectiveness and Safety for Surgery for Kids Trial
This trial is being completed to compare two commonly used options to treat pain after discharge from surgery. Participants that undergo tonsil removal, gallbladder removal, and knee scope will be eligible to enroll.
- Trial name
- CARES for Kids (NCT06671002)
- Testing
- NSAID, Opioid, Acetaminophen
- Where
- 9 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Michigan
Arthroplasty, Replacement, Knee, Pain, Postoperative
Central Sensitization and Alteration of Circulating Neurosteroid
For patients who underwent two-stage replacement of both knee joints (one knee surgery - one week term- the other knee surgery), postoperative pain and analgesic usage with patient-controlled analgesia (PCA) increased at the…
- Trial name
- NCT03298711
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Seoul National University Bundang Hospital
Hemophilia A
Effects of Ultrasound and Infrared on Joint Pain and Movement in Hemophilia A Patients.
The study aims to compare the effectiveness of therapeutic ultrasound and infrared in managing hemarthrosis in patients with Hemophilia A, focusing on specific outcomes like joint pain, swelling, muscle atrophy, and range of…
- Trial name
- Hemophilia A (NCT07116993)
- Testing
- theraputic ultrasound, infrared radiation
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Danyal Ahmad
Patellofemoral Pain Syndrome, Knee Pain
5 Year Follow-up of Adolescents With Knee Pain
The prevalence of adolescent knee pain is 33%, and patellofemoral pain (PFP) is the most common diagnosis with a nontraumatic onset. The 5-year prognosis of adolescent PFP compared with other types of knee pain is unknown.
- Trial name
- NCT02873143
- Testing
- No intervention
- Volunteers
- 540 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Total Knee Replacement
The Clinical Observation on Taping After Total Knee Replacement
The investigators will conduct a single-blind, randomized controlled trial of 100 patients with total knee replacement. Patients will be randomly assigned into a control group and an intervention group.Both groups received same…
- Trial name
- taping (NCT03340584)
- Testing
- the Nine Castle Net Format Taping, traditional rehabilitation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Knee Pain
A Reliability and Validity Study of Urdu Version of Knee Outcome Survey-Activities of Daily Living Scale
The purpose of this study is to translate Knee Outcome Survey-Activities of Daily Living Scale into Urdu language and to check the reliability and validity of the Knee Outcome Survey-Activities of Daily Living Scale in Urdu…
- Trial name
- NCT05221047
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Riphah International University
Pain, DKV
Core and Hip-Knee Exercises in PFPS
Study Purpose: The purpose of this study is to investigate the effect of adding core muscle strengthening exercises to a hip- and knee-focused exercise program on pain intensity, dynamic knee valgus (DKV), and functional outcomes…
- Trial name
- DKV (NCT07531550)
- Testing
- Core Muscle Stability Exercise Program, hip and knee-focused exercise program
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University
Patellofemoral Pain Syndrome
Comparing Rehabilitation Programs for Patellofemoral Pain Syndrome
Patellofemoral pain syndrome (PFPS) is a common knee disorder affecting physically active people. Despite the growing base of support for the early introduction of hip strengthening exercises into the rehabilitation of PFPS…
- Trial name
- NCT00445224
- Testing
- Hip Progressive Resistive Exercise, Quad Progressive Resistive Exercises
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Timothy Uhl
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Dynamic Q Angle and Core Endurance in Adolescent Athletes With Patellofemoral Pain Syndrome
This observational, cross-sectional study aimed to compare dynamic Q-angle, trunk/core endurance, and lower-extremity flexibility between elite adolescent female and male sprinters with and without patellofemoral pain syndrome…
- Trial name
- PFPS-QCORE (NCT07328750)
- Testing
- Patellofemoral Pain Syndrome Status
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Knee Osteoarthritis
Pain Compared Between the First and the Second Surgery in Staged BTKA
postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).
- Trial name
- NCT01457313
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Knee
Pain Relief Effect of Low-intensity Continuous Ultrasound Stimulator for Knee Arthritis
The goal of this clinical trial is to test low-intensity continuous ultrasound stimulator(LICUS) for patients suffering from knee arthritis. it aims to evaluate the pain relief effect of LICUS.
- Trial name
- NCT05657535
- Testing
- Low-intensity continuous ultrasound stimulator
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kyu Jae Lee
Knee Pain Treated With Knee Arthroplasty
Changes of Plantar Pressure After Knee Reconstructive Surgery
Knee reconstructive surgery (knee prosthesis, osteotomies) often results in changes of alignment of the lower limb axis. This affects also biomechanics of the hindfoot.
- Trial name
- PEDKnee (NCT02906735)
- Testing
- Surgery
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Post Operative Pain
Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair
One of the most common injuries to the knee is an anterior cruciate ligament (ACL) sprain or tear due to trauma ACL damage is crippling and often requires repair with an arthroscopic method, which is an outpatient surgery.
- Trial name
- NCT06404658
- Testing
- Genicular nerve block
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Osteoarthritis, Knee
Comparison of Heated vs. Pulsed Radiofrequency Treatment of the Genicular Nerves for Osteoarthritis Knee Pain
This is a prospective, randomised, interventional, double blinded study to compare the clinical outcomes of thermal vs. pulsed radiofrequency (RF) treatment of the genicular nerves in patients with painful osteoarthritis (OA) of…
- Trial name
- NCT04379895
- Testing
- Radiofrequency ablation
- Volunteers
- 60 people
- Sponsor
- Rambam Health Care Campus
Painful Osteoarthritis of the Knee
Radiofrequency Ablation of Genicular Nerves for Advanced Osteoarthrosis of the Knee Joint 1 Year Follow-up.
Pharmacological treatment of pain due to osteoarthritis of the knee often proves to be inadequate and/or cause intolerable side effects.
- Trial name
- NCT02688543
- Testing
- RF treatment, radiofrequency ablation, ultrasound
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Hospital General de Jerez de la Frontera
Childhood Obesity
Biofeedback Gait Retraining to Reduce Lower Extremity Impact in Obese Children
The purpose of the study is to explore if self biofeedback program can reduce ground reaction force (GRF) from the lower extremity of the body and in the knee in particular and help obese children to avoid knee injuries.
- Trial name
- NCT02580825
- Testing
- Biofeedback gait retraining, Exercise
- Where
- Israel
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark