Clinical trials: Knee Prosthesis
Osteoarthritis
Comparing Fixed-bearing Versus Mobile-bearing Prosthesis in Total Knee Arthroplasty: A Prospective Randomized Trial
The purpose of this study is to determine which prosthesis is better in total knee arthroplasty
- Trial name
- NCT01312532
- Testing
- fixed-bearing (P.F.C.® Sigma), mobile-bearing (P.F.C.® Sigma)
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Osteoarthritis of the Knee Joint
Correlation Between Alignment of Lower Limb and Clinical Outcome After Total Knee Prosthesis.
Evaluation of the clinical results after total knee prosthesis, and correlation with the alignment of the lower limb. Radiological measurements by means of 3D technology will be performed.
- Trial name
- NCT01666873
- Testing
- patients that undergo a total knee prosthesis
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- University Hospital, Ghent
Prosthesis-related Infections, Staphylococcal Infections
Rifampin Combination Therapy Versus Monotherapy in Early Staphylococcal Infections After Total Hip and Knee Arthroplasty
The number of patients requiring joint replacement is increasing due to its success in restoring function and pain relief, and the growing population of the elderly.
- Trial name
- NCT00423982
- Testing
- Rifampin-combination therapy, Monotherapy
- Where
- 8 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Osteoarthritis, Metal Ion Levels
Serum Metal Ion Concentration After Total Knee Arthroplasty (TKA)
All metal implants release metal ions because of corrosion. Total knee arthroplasty implants have large metal surface areas and therefore substantial potential for corrosion.
- Trial name
- NCT00862511
- Testing
- Coated Total Knee Arthroplasty, Standard Total Knee Arthroplasty
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Technische Universität Dresden
Osteo Arthritis Knee
Evaluation of Standard and Robot Assisted Total Knee Arthroplasty with a Bicrucatie Retaining Prosthesis
The first study goal is to compare the outcomes between Posterior Stabilized and Bicruciate Retaining TKA. Additionally, the second goal is to evaluate the effect of robot assisted surgery in both Posterior Stabilized and…
- Trial name
- NCT04334304
- Testing
- Total Knee Prosthesis - type Bicruciate retaining, Robot-assisted Total Knee Arthroplasty, Total Knee Prosthesis - type Posterior Stabilized
- Where
- Belgium
- Volunteers
- 47 people
- Sponsor
- University Hospital, Ghent
Osteoarthritis of the Knee, Female
A Gender-Specific Posterior Cruciate-Substituting High-Flexion Knee Prosthesis Does Not Improve Fit and Function
The purpose of this study was to compare functional and radiographic results, range of motion of the knee, patient satisfaction, femoral component, revision and complication rates in patients receiving either a standard posterior…
- Trial name
- NCT00917774
- Testing
- Standard LPS flex TKA, Gender specific LPS -Flex TKA
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Ewha Womans University
Osteoarthritis
Range of Motion of Standard and High-Flexion Posterior Cruciate Retaining Total Knee Prostheses
The purpose of this prospective, randomized study was to compare pain, functional outcome and ranges of motion of the knees in patients receiving either a standard posterior cruciate-retaining or a high-flexion posterior…
- Trial name
- NCT00837447
- Testing
- Total knee replacement with NexGen CR knee prosthesis, Total knee replacement(TKR) with Nexgen CR-flex
- Volunteers
- 54 people
- Sponsor
- Ewha Womans University
Implant Infection, Skeletal Sarcoma
Implant-Related Infections in Patients With Skeletal Sarcomas
The aim of this observational study is to gain knowledge on the microbial and immunological factors behind implant-related infections in patients with skeletal sarcoma.
- Conditions
- Implant Infection, Skeletal Sarcoma, Hip Arthritis, Prosthesis-Related Infections
- Trial name
- IRISSAR (NCT07264296)
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Stress
Effect of Audio Book applıcatıon on patıents Blood Pressure, Pulse Rate and anxıety Levels Before Total Knee Replacement Surgery
Before the TDP surgery, the anxiety levels of the patients in the experimental group will be measured by listening to an audio book.
- Trial name
- NCT06905899
- Testing
- audiobook app
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Beyza Yilmaz
Prosthesis-Related Infections, Hip Prosthesis Infection
Effect of Sonication on Periprosthetic Joint Infection Treatment Strategy.
It is not known in the literature how much sonication affects the patient's treatment. Another important issue is that the place of this method in diagnosis is not clear.
- Conditions
- Prosthesis-Related Infections, Hip Prosthesis Infection, Joint Infection, Biofilm
- Trial name
- NCT04304885
- Testing
- Sonication method
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Bezmialem Vakif University
Transtibial Amputation
Temporary Prosthesis in Traumatic Below-knee Amputation
Most trauma survivors in low-income countries develop post-injury chronic pain syndromes. Normally traumatic amputees have to wait 4-6 months for definitive prosthesis fitting.
- Trial name
- NCT00263497
- Testing
- Temporary tuber-ischii bearing prosthesis
- Where
- Cambodia
- Volunteers
- 20 people
- Sponsor
- University Hospital of North Norway
Total Knee Replacement
10 Year Outcome of Total Knee Replacement (TKR) Using Sigma Prosthesis
The purpose of this study is to obtain a prospective database which will allow analysis of total knee outcomes.
- Trial name
- NCT01522781
- Where
- United Kingdom
- Volunteers
- 234 people
- Sponsor
- NHS Fife
Osteoarthritis
A Post-Market Retrospective Study on Revision Total Knee Arthroplasty Using Medacta GMK® Revision Prosthesis
This is a retrospective, single-site observational study, designed to assess the clinical outcomes and collect safety data of GMK Revision knee system used for primary or revision total knee arthroplasty at minimum two years…
- Trial name
- NCT02912351
- Testing
- Patient record review, Radiographs, and questionaires.
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Osteoarthritis
A Randomized Control Trial to Assess Early Clinical and Functional Outcome of the ROCC and LCS Total Knee Implant Designs
This is a prospective Randomised Control Trial to compare the Early Clinical and Functional Outcome of the ROCC and LCS total knee arthroplasty implant designs.
- Trial name
- NCT00755144
- Testing
- LCS Knee, ROCC Knee
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Zimmer Biomet
Amputation
Effectiveness of Frontal Plane Adaptability in a Novel Foot Prosthesis
People with lower extremity amputation (LEA) have persistent problems with balance, falls, residual limb pain, functional mobility, cognitive attention during gait, and satisfaction with participation in daily activities, despite…
- Trial name
- NCT06214026
- Testing
- META-Arc foot locked, META-Arc foot unlocked
- Where
- 3 sites in United States
- Volunteers
- 96 people
- Sponsor
- University of Washington
Total Knee Arthroplasty
Comparison Of Outcomes After Knee Arthroplasty Using Posterior-Substituting Versus Cruciate-Retaining Prostheses
Total knee replacement is used in the treatment of patients with knee arthritis, rheumatoid arthritis and other knee disorders. Today, there are basically two designs; It cuts the posterior cruciate ligament (PS) and protects the…
- Trial name
- NCT06170931
- Testing
- posterior cruciate ligament-retaining prostheses, posterior cruciate ligament-substituting prostheses
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Bezmialem Vakif University
Prosthesis Survival
Multicenter Perspective Study: Clinical Evaluation of the Persona MC® With Preservation or Sacrifice of the PCL
Prospective, multicenter study on the Total Knee Prosthesis available on the market "Persona Medial Congruent® knee". Primary endpoint -Evaluation of the survival of the implant after 5 years of follow-up Secondary endpoints…
- Trial name
- NCT04244929
- Testing
- Total knee arthroplasty, Persona Medial Congruent Knee Prosthesis implantation with Posterior Cruciate Ligament retaining, Persona Medial Congruent Knee Prosthesis implantation with Posterior Cruciate Ligament sacrifice
- Where
- Italy
- Volunteers
- 7 people
- Sponsor
- Istituto Ortopedico Rizzoli
Clinical Practice Guidelines, Lower Limb Amputation Above Knee (Injury)
TeleEducation for Implementing a Clinical Practice Guideline For Amputees
The publication of a Clinical Practice Guideline (CPG) is often not enough for its correct use in the field of health care. There are barriers to the implementation of the CPG recommendations, including those related to the lack…
- Conditions
- Clinical Practice Guidelines, Lower Limb Amputation Above Knee (Injury), Lower Limb Amputation Below Knee (Injury), Lower Limb Amputation Knee
- Trial name
- TEFICA (NCT05601349)
- Testing
- Telehealth-based strategy
- Where
- Colombia
- Volunteers
- 7 people
- Sponsor
- Grupo Rehabilitacion en Salud
Rheumatoid Arthritis
Early Migration in a High Congruent Rotating Platform Total Knee Prosthesis Design
The aim of this study is to accurately assess the relationship between knee joint kinematics and migration of the tibial component of a high congruent, rotating platform total knee prosthesis by using fluoroscopy synchronised in…
- Trial name
- ROCC (NCT01102829)
- Where
- Netherlands
- Volunteers
- 11 people
- Sponsor
- Leiden University Medical Center
Prosthesis Failure
Medium-term Results of the LPS™ System for Segmental Resection of the Distal Femur, a Multicenter Retrospective Study (RESIF)
The reconstruction of the distal femur using modular systems has become increasingly popular over the years, surpassing primary arthrodesis or amputation.
- Trial name
- RESIF (NCT06928948)
- Testing
- Femur replacement
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Brest