Clinical trials: Knee Replacement, Total
Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
Effects of Stress Ball Use and Breathing Exercises on Pain and Vital Signs During Drain Removal After Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effects of stress ball use and breathing exercises on procedural pain and vital signs during drain removal in patients undergoing total knee arthroplasty.
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery, Pain After Knee Arthroscop
- Trial name
- TDP (NCT07586436)
- Testing
- 3. Control Group Description, 1. Stress Ball Intervention Description, 2. Breathing Exercise Intervention Description
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Revision Total Knee Replacement
Pilot Study Using Radiostereometric Analysis (RSA) to Evaluate the Fixation of the Tibial Components in the DePuy M.B.T. Revision Knee System
Motivated by the growing number of revision total knee arthroplasty (TKAs) and the interest among surgeons to quantify the effectiveness of specific implant designs, the goal of the current project is to use Radiostereometric…
- Trial name
- NCT01647386
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Michael Dunbar
Knee Arthritis
Perioperative Analgesia for Knee Arthroplasty (PAKA)
Peri-articular knee infiltration with Levobupivicaine 150mg, Morphine 10mg and Ketorolac 30mg reduces postoperative pain following primary total knee replacement compared with the current standard treatment of femoral nerve…
- Trial name
- PAKA (NCT01560767)
- Testing
- Femoral Nerve Block, peri-articular infiltration
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- University of Warwick
Arthrosis
Topical Versus Intravenous Tranexamic Acid in Total Knee Arthroplasty
This clinical trial investigated two different routes of administration of tranexamic acid in total knee arthroplasty: topical compared to intravenous.
- Trial name
- TRANEXTKA (NCT02323373)
- Testing
- Tranexamic Acid - topical, Tranexamic Acid - intravenous
- Volunteers
- 90 people
- Sponsor
- Irmandade da Santa Casa de Misericordia de Sao Paulo
Osteoarthritis (OA) of the Knee, Total Knee Anthroplasty
Comparison of Restricted Versus Unrestricted Kinematic Alignment in 1ry TKA
Knee osteoarthritis is a growing socioeconomic burden because of the ageing and obesity. By 2030, the majority of individuals undergoing knee arthroplasty in USA will be those younger than 65 years, with up to 1 million achieved…
- Trial name
- rKA-KA-TKA (NCT06726993)
- Testing
- Total knee arthroplasty
- Volunteers
- 80 people
- Sponsor
- Assiut University
Total Knee Arthroplasty, Telehealth
The Effect of Tele-Health Application on Functional Status, Self-Care Ability and Activities of Daily Living in Individuals Undergoing Total Knee Arthroplasty Surgery
Osteoarthritis, defined as a degenerative joint disease, is a chronic, non-inflammatory condition characterized by deterioration of joint cartilage and new bone formation on joint surfaces and margins.
- Conditions
- Total Knee Arthroplasty, Telehealth, Self-Care Ability
- Trial name
- (TKA-TELECARE) (NCT07380724)
- Testing
- tele health
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya Applied Sciences University
Osteoarthritis
Proprioception of the Knee Post MIS TKA and MIS-QS TKA
If the proprioception of the affected knee post total knee arthroplasty (TKA) can recover earlier, it will accelerate the regaining of motion control ability and motion control accuracy of the TKA patients.
- Trial name
- NCT02160977
- Testing
- total knee arthroplasty
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Jia-kuo yu
Total Knee Artroplasty
Influence of Weight-bearing Mechanical Axis on Foot and Ankle in Patients Following Total Knee Arthroplasty
This comprehensive scientific research will investigate the influence of the weight-bearing mechanical axis on foot and ankle following total knee arthroplasty.
- Trial name
- NCT05751954
- Testing
- Postero-anterior weight-bearing full-leg radiograph, Pedobarographic analysis
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- Clinic for Orthopedics Lovran
Osteoarthritis
Adductor Canal Block Versus Periarticular Bupivicaine Injection in Total Knee Arthroplasty
The objective of the study is to compare the efficacy of adductor canal blocks versus periarticular bupivacaine injections for pain management in total knee arthroplasty.
- Trial name
- NCT02777749
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 155 people
- Sponsor
- Columbia University
Knee Arthritis
Knee Arthroplasty Performed With Conventional and Customized Instrumentation
The main purpose of this study is to determine whether the surgical time required for primary total knee arthroplasty is significantly less when performed with Customized Patient Instrumentation (CPI) than with conventional…
- Trial name
- CPI (NCT01124305)
- Testing
- Customized Patient Instrumentation, Traditional Instrumentation
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Anderson Orthopaedic Research Institute
Osteoarthritis
Standard Total Knee Arthroplasty Using Platelet Rich Plasma (PRP)
Clinical study to determine if there is a difference in hemoglobin level between patients undergoing total knee arthroplasty with and without platelet-rich plasma.
- Trial name
- NCT01075230
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Exactech
Knee Osteoarthritis
Evaluation of the Effect of SURGICEL® Powder in TKA
The study subjects are patients in our hospital's orthopedics department undergoing unilateral primary total knee arthroplasty (TKA) due to primary osteoarthritis.
- Trial name
- NCT06608992
- Testing
- SURGICEL® Powder
- Where
- China
- Volunteers
- 112 people
- Sponsor
- Peking University Third Hospital
Total Knee Arthroplasty
Return Physical Activities After Total Knee Arthroplasty
The ability to resume physical activities, aerobic fitness and a healthy lifestyle without symptoms after total knee arthroplasty (TKA) remains unclear because studies show high rates of patient dissatisfaction.
- Trial name
- NCT04746144
- Testing
- Total knee arthroplasty
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Cincinnati Sportsmedicine Research and Education Foundation
Knee Pain
Safety and Efficacy of Botulinum Toxin A Injection in Patients With Painful Artificial Knee Arthroplasty (TKA)
Primary Total Knee joint replacement surgery is highly successful surgery for relieving pain and improving function in patients with disabling arthritis.
- Trial name
- NCT00403273
- Testing
- Botulinum toxin A, Normal Saline
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Total Knee Replacement
Fluoroscopic Analysis of Total Knee Replacement With a Kinematic Retaining or a Posterior Stabilized Design
The aim of this study is to evaluate the in vivo kinematics of TKA performed with two different prosthesis: a kinematic retaining (Physica KR) and a posterior-stabilized (Physica PS) design by means of fluoroscopic analysis…
- Trial name
- NCT02706990
- Testing
- Physica KR, Physica PS
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Limacorporate S.p.a
Knee Arthropathy, Anesthesia, Local
Modified TIPS Block for Total Knee Arthroplasty
The is carried out to compare triple injection peri-sartorial block to a modified block including an extra local anesthetic injection deep to the adductor longs muscle via a medial to lateral approach regarding the peri-operative…
- Trial name
- NCT06539910
- Testing
- General Anesthesia, TIPS block, Modified TIPS block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Total Knee Replacement Revision
LEGION™ Revision Metal Hypersensitivity Study
This is a prospective, randomized, multi-center, metal hypersensitivity study comparing OXINIUM and cobalt chrome femoral components in subjects with failed total knee arthroplasty (TKA).
- Trial name
- NCT02412813
- Testing
- LEGION OXINIUM, LEGION Cobalt Chrome
- Where
- 3 sites in United States, Canada
- Sponsor
- Smith & Nephew, Inc.
Prosthesis-related Infections, Staphylococcal Infections
Rifampin Combination Therapy Versus Monotherapy in Early Staphylococcal Infections After Total Hip and Knee Arthroplasty
The number of patients requiring joint replacement is increasing due to its success in restoring function and pain relief, and the growing population of the elderly.
- Trial name
- NCT00423982
- Testing
- Rifampin-combination therapy, Monotherapy
- Where
- 8 sites in Norway
- Volunteers
- 100 people
- Sponsor
- Oslo University Hospital
Osteoarthritis
The HIHO Study: Hospital Inpatient vs Home Rehabilitation After Total Knee Replacement
Total knee replacement (TKR) surgery is a common and highly effective treatment option for alleviating the pain and disability caused by chronic arthritis.
- Trial name
- HIHO (NCT01583153)
- Testing
- Hospital Inpatient Rehabilitation, Hybrid Home Programme (HO)
- Where
- 3 sites in Australia
- Volunteers
- 165 people
- Sponsor
- Mark Buhagiar
Osteoarthritis, Knee, Joint Disease
Matched Pair Study - Kinematic Vs Mechanical Alignment
The aim of this study is to evaluate postoperative knee function after total knee arthroplasty performed according to the anatomical alignment and compare these results to those of a matched historical cohort of patients operated…
- Trial name
- NCT03446391
- Testing
- Kinematic alignment, Mechanical alignment, GMK Sphere®
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Medacta International SA