Clinical trials: Knee Surgery
Total Knee Replacement
Qualitative Interviews With Healthcare Professionals
PLANNING PHASE- Qualitative interviews with Healthcare Professionals to assist in the development of a new Patient Reported Outcome Measure (PROM) to assess patient's emotional wellbeing, and perceptions of Total Knee Replacement…
- Trial name
- NCT05597046
- Testing
- Interview
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Invibio Ltd
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
In primary pediatric Anterior cruciate ligament (ACL) reconstruction, the quadriceps tendon with either tendon and patellar bone or an all-tendon graft is commonly employed.
- Conditions
- Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Anterior Cruciate Ligament Tear
- Trial name
- NCT04039971
- Testing
- ACL Reconstruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Pain, Postoperative, Knee Arthroscopy
Postoperative Pain Between ACB and FNB After ACLR
The aim of this study is to compare the efficacy in pain relief within 24 hours between adductor canal block and femoral nerve block after anterior cruciate ligament reconstruction with hamstring graft.
- Conditions
- Pain, Postoperative, Knee Arthroscopy, Anterior Cruciate Ligament/Surgery
- Trial name
- NCT02411890
- Testing
- Adductor canal block (active), Femoral nerve block (active)
- Where
- Thailand
- Volunteers
- 60 people
- Sponsor
- Thammasat University
Cruciate Ligament Rupture
Stability of the Knee Joint After Anterior Cruciate Ligament and Anterolateral Ligament Reconstruction
The objective of this randomised cohort study was to evaluate the knee rotational stability after the single-bundle ACL reconstruction (SB) with addition of the ALL reconstruction and to compare it with the double-bundle ACL…
- Trial name
- NCT02993679
- Testing
- reconstruction of the ACL and anterolateral ligament
- Volunteers
- 60 people
- Sponsor
- Hospital Znojmo
Anterior Cruciate Ligament Injury, Knee Injury
Comparison of Quadriceps and Semitendinosus Grafts in ACL Reconstruction Using Data From the Danish Knee Ligament Reconstruction Registry (DKRR)
This study looks at two different types of tendon (tissue) used in knee surgery to repair a torn anterior cruciate ligament (ACL), which is a common injury in active people.
- Conditions
- Anterior Cruciate Ligament Injury, Knee Injury, Ligament Reconstruction, Sports Injuries
- Trial name
- NCT06980285
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Abdirahman Hassan Omar
Anterior Cruciate Ligament Rupture
Improving Maximal Strength in the Initial Postoperative Phase After Anterior Cruciate Ligament Reconstruction Surgery: Randomized Controlled Trial of an App-Based Serious Gaming Approac
The investigators designed a prospective randomized trial to evaluate whether an app based active muscle training program (GenuSport) can improve the postoperative strength by starting rehabilitation immediately after primary…
- Trial name
- NCT04224376
- Testing
- App based Serious Gaming with the Genu Sport knee trainer
- Volunteers
- 26 people
- Sponsor
- Hannover Medical School
Osteoarthritis, Knee
Conventional Alignment System Versus Surgical Navigation System in Total Knee Arthroplasty
This is a randomized, controlled, blinded prospective study comparing the use of the usual cutting guides with a palm-sized digital surgical navigation system in unilateral total knee arthroplasty.
- Trial name
- NCT01797731
- Testing
- Digital hand-held surgical navigation system, Conventional tibial extramedullary alignment system
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Hospital for Special Surgery, New York
Meniscus Injury
Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury
Through the analysis of the data of 8094 patients with knee meniscus injury before December 31, 2008 and more patients with partial meniscus resection, subtotal resection and total resection, we can understand the gender…
- Trial name
- NCT04962555
- Testing
- Meniscus Suture, Partial meniscus resection, Subtotal meniscus resection
- Where
- China
- Volunteers
- 8,778 people
- Sponsor
- Peking University Third Hospital
Periprosthetic Knee Infection
Outcome After Revisions of Infected Knee Arthroplasties
A prospective multicenter cohort study on all types of revision knee arthroplasty procedures performed due to infection.
- Trial name
- RIKA (NCT04427943)
- Testing
- revision surgery
- Where
- 8 sites in Denmark
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Pain, Spinal Surgeries, Hip and Knee Joint Replacement, Adverse Events
RAHM Foundation Retrospective Study of Various Diseases
This is a retrospective data collection on treatment of various disorders. This registry will include a variety of different products, implants, technologies and procedures.
- Trial name
- NCT02359786
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Rahm Foundation
ACL Injury, ACL Tears
Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction
This is a prospective, multi-center, randomized, double-blind, placebo-controlled trial evaluating the efficacy of oral tranexamic acid (TXA) in improving postoperative outcomes following anterior cruciate ligament reconstruction…
- Conditions
- ACL Injury, ACL Tears, ACL Surgery
- Trial name
- NCT07115056
- Testing
- Tranexamic Acid (TXA)
- Where
- 6 sites in United States
- Sponsor
- Campbell Clinic
Osteo Arthritis Knee, Surgery
Dynamic Congruence Total Knee Replacement vs Posterior-stabilized
This study compares and evaluates differences in movement analysis, patient-reported outcome between patients undergoing total knee arthroplasty with use of either Zimmer Biomet NexGen with posterior stabilization and Bioimplanti…
- Conditions
- Osteo Arthritis Knee, Surgery, Joint Diseases
- Trial name
- K-Mod (NCT04524312)
- Testing
- Total knee replacement, Biomechanics, NexGen Ps or Bioimplanti K-MOD implant
- Where
- Poland
- Volunteers
- 56 people
- Sponsor
- Medical University of Warsaw
Postoperative Pain
Arthroplasty Inflammation Prophylaxis With Celecoxib
This double blinded, placebo controlled, study seeks to determine the efficacy of preoperative anti-inflammatory therapy on the reduction of postoperative pain in knee arthroplasty surgery.
- Trial name
- NCT00533247
- Testing
- Celecoxib
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zanbilowicz, Adam, DPM MS
Patellofemoral Dislocation
Assessment of Surgical Correction of Patello-femoral Instability by EOS 3D Kinematics
Assessment of surgical correction of patello-femoral instability by EOS 3D kinematics
- Trial name
- EOS-FP2017 (NCT04143438)
- Testing
- EOS 3D imaging protocol pre- and post-surgery
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Montpellier
Dexmedetomidine, Femoral Nerve Block
Dexmedetomidine in Different Dose Levels as Adjuvant to Bupivacaine-induced Ultrasound-guided Femoral Nerve Block.
The duration of sensory block after single dose of long acting local anesthetics is not sufficient to avoid the postoperative use of opioids.
- Conditions
- Dexmedetomidine, Femoral Nerve Block, Arthroscopic Knee Surgery
- Trial name
- NCT02089932
- Testing
- peri-neural dexmedetomidine as adjuvant to bupivacaine in femoral nerve block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Postoperative Complication
Efficacy of Wound Care and Reduction of Wound Complications by Use of AQUACEL® Ag Surgical Dressing in MIS TKA
The investigators hypothesized that AQUACEL® Ag Surgical dressing would have a significant improvement in the efficacy of wound care and wound complications compared with traditional Sofra-Tulle® dressings after minimally…
- Trial name
- NCT02445300
- Testing
- AQUACEL® Ag Surgical dressing (study group), Sofra-Tulle® dressing (control group)
- Volunteers
- 285 people
- Sponsor
- Chang Gung Memorial Hospital
Achilles Tendon Surgery, Cerebral Palsy
Gastrocsoleus Lengthening in Cerebral Palsy
The goal of this study is to compare passive ankle and knee range of motion (ROM) development after surgery to the gastrocsoleus complex, in children with cerebral palsy (CP).
- Trial name
- NCT05783739
- Volunteers
- 186 people
- Sponsor
- Region Skane
Cerebral Palsy
Distal Rectus Femoris Transfer as a Part of Multilevel Surgery in Children With Spastic Diplegia
The purpose of this study is to evaluate the effects of an additional distal rectus femoris transfer carried out as a part of single-event multilevel surgery in children with spastic diplegic cerebral palsy.
- Trial name
- RectusTrans (NCT01381198)
- Testing
- Distal rectus femoris transfer
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Heidelberg University
Polydactyly Toe, Thumb Hypoplasia
Clonidine for Tourniquet-related Pain in Children
This study is designed as a randomized, placebo-controlled, double-blinded, clinical trial with two parallel groups. This study investigates the association between a single dose of the drug, Clonidine, and the total amount of…
- Conditions
- Polydactyly Toe, Thumb Hypoplasia, Trigger Finger, Polydactyly; Fingers
- Trial name
- CLOTCH (NCT04564430)
- Testing
- Catapresan, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Psychological Stress, Cardiopulmonary Bypass Surgery
CARINAE for Stress Relief in Perioperative Care
Preventing pre-surgical stress can help patients achieve positive outcomes on health and well-being. However, very few patients receive adequate stress relief support prior to a surgical procedure.
- Conditions
- Psychological Stress, Cardiopulmonary Bypass Surgery, Coronary Artery Bypass Surgery, Cardiac Valve Replacement
- Trial name
- CARINAE (NCT05184725)
- Testing
- SaMD CARINAE
- Where
- 5 sites in Italy, Netherlands and 1 more
- Volunteers
- 50 people
- Sponsor
- Adhera Health, Inc.