Clinical trials: LET
Children's Wellbeing, Child Overall Health Related Quality of Life
Let´s Talk About Children Intervention in a School Context
The aim of this study is to examine the fidelity, the perceived benefits, and the effectiveness of the Let's Talk about Children (LTC) -intervention in a school context.
- Conditions
- Children's Wellbeing, Child Overall Health Related Quality of Life, Burnout
- Trial name
- NCT05038280
- Testing
- Let's Talk about Children intervention
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Laceration, Pain
The Addition of Oral Analgesics to LET During Laceration Repair
Background Approximately 30 million children are treated in emergency departments each year in the United States, of which two to three million are children presenting with lacerations.
- Trial name
- NCT01268670
- Testing
- Ibuprofen, Oxycodone
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Stress, Sleep Disturbance
Let´s Talk About Sleep in College Student
The concern about the quality of sleep of university students, future professionals of the world, must be crucial for the scientific community, as well as for university professors and professors.
- Trial name
- USLEEP (NCT05265494)
- Testing
- Non invasive neuromodulation NESA (XSIGNAL device)
- Where
- 2 sites in Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Las Palmas de Gran Canaria
Chin Injury
Effect of Maternal Kisses on Pain, Anxiety, and Fear
Although the effectiveness of maternal kisses for minor injuries in childhood is traditionally accepted, its effect on invasive procedures has not yet been proven.
- Trial name
- NCT05892601
- Testing
- Maternal kisses
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Bandırma Onyedi Eylül University
Anaplastic Ependymoma, Ependymoma
LET Optimized IMPT in Treating Pediatric Patients With Ependymoma
This phase I trial studies the side effects of linear energy transfer (LET) optimized image modulated proton therapy (IMPT) in treating pediatric patients with ependymoma.
- Trial name
- NCT03750513
- Testing
- Linear Energy Transfer-Optimized Intensity Modulated Proton Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- M.D. Anderson Cancer Center
Appendicitis
Laparoscopic Versus Open Appendectomy? Let the Patient Decide
This protocol examines choice where it pertains to choosing between two standard methods for appendectomy, laparoscopic or open procedures, and the affect that "cost" of the appendectomy has upon choice.
- Trial name
- NCT01738750
- Testing
- Cost Information Included
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Lacerations
Gluing Lacerations Utilizing Epinephrine
Minor lacerations are a commonly treated injury in the paediatric emergency department . Over the past decade, standard closure of these lacerations has evolved from suture repair to closure with tissue adhesive (also referred to…
- Trial name
- GLUE (NCT01202487)
- Testing
- LET - Lidocaine Epinephrine Tetracaine
- Where
- Canada
- Volunteers
- 222 people
- Sponsor
- Children's Hospital of Eastern Ontario
Anterior Cruciate Ligament Reconstruction (ACLR)
The Effect of Lateral Extra-Articular Tenodesis on Lower-Extremity Lean Mass Recovery Following Anterior Cruciate Ligament Reconstruction
The purpose of this study is to determine whether the addition of Lateral Extra-Articular Tenodesis (LET) influences postoperative lower-extremity LM recovery following bone-patellar tendon-bone (BTB) Anterior Cruciate Ligament…
- Trial name
- NCT07777458
- Testing
- Bone-patellar Tendon-bone (BTB), Bone-patellar Tendon-bone (BTB) and Lateral Extra-Articular Tenodesis (LET)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
LET, ACL Reconstruction
Long-term Follow up of the Stability 1 Trial
From 2014-2017, across 7 Canadian and 2 European sites, we randomized 618 patients at high-risk of re-injury, to anterior cruciate ligament reconstruction (ACLR) with or without a lateral extraarticular tenodesis (LET) and…
- Conditions
- LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
- Trial name
- STABILITY LTF (NCT06885372)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Canada, United Kingdom
- Volunteers
- 510 people
- Sponsor
- Western University, Canada
Malignant Central Nervous System Neoplasm, Malignant Skull Base Neoplasm
Brain Imaging Changes Following Proton Therapy for Pediatric Primary Central Nervous System and Base of Skull Tumors
This trial gathers information from patients with primary central nervous system or base of skull tumors that receive proton beam therapy and see if certain imaging techniques can help detect radiation-related changes over time.
- Trial name
- NCT04296617
- Testing
- Medical Chart Review
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Mayo Clinic
Anterior Cruciate Ligament Reconstruction
Standard ACL Reconstruction vs ACL + Lateral Extra-Articular Tenodesis Study
The purpose of this study is to compare outcomes (failure, function, strength, range of motion and quality of life) between patients who receive the usual anterior cruciate ligament (ACL) reconstructive surgery and patients who…
- Trial name
- STAbiLiTY (NCT02018354)
- Testing
- Lateral Extra-Articular Tenodesis (LET), ACL Reconstruction
- Where
- 8 sites in Belgium, Canada and 1 more
- Volunteers
- 624 people
- Sponsor
- University of Western Ontario, Canada
Parent Training, Parent Child Relationship
Hold me Tight/Let me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship
HmT/LmG is a group course for 4-6 parental dyads and consists of 4 group sessions with psycho-education and skills training and 3 individual sessions per family (i.e., 1 session with the adolescent, 1 session with the parents…
- Conditions
- Parent Training, Parent Child Relationship, Parent-child Problem
- Trial name
- NCT06966323
- Testing
- Hold me Tight / Let me Go
- Where
- 5 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- University of Amsterdam
Lacerations, Pain, Procedural
Comparison of Two Application Techniques for LET Gel
Comparison of anesthetic efficacy of Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel (LET) applied three times for 10 minutes each time vs.
- Conditions
- Lacerations, Pain, Procedural, LET
- Trial name
- NCT04203225
- Testing
- LET Lidocaine (4%), Epinephrine (0.1%), and Tetracaine (0.5%) topical gel
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Tic Disorder, Provisional Tic Disorder
Let It TiC in Childhood Provisional Eye Tic
Clarify the effectiveness and safety of "Reduced-Attention Intervention Therapy" in treating children with Provisional tic disorder （PTD） who mainly exhibit abnormal blinking behavior
- Trial name
- LETITTIC (NCT07838428)
- Testing
- Reducing Attentional Interventions Therapy Treatment, Continue with the previous treatment plan
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
LET, Laceration of Skin
Comparison of 2 Application Techniques for LET Gel Used Prior to Simple Laceration Repair
To compare pain scores during laceration repair with first suture placement using standardized visual analog scale (VAS) between 2 different topical local anesthetic application techniques for using LET gel.
- Trial name
- LET (NCT04536493)
- Testing
- LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (1 application), LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (3 applications)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Children's Hospital of Orange County
Sepsis, Length of Stay
Limited Versus Extended Trophic Feeding (LET-FEED) Trial
Study Hypothesis/Question In infants born very preterm, advancing enteral feeds after 24 hours from birth (limited trophic feeds) versus after 72 hours (extended trophic feeds) reduces the risk of all-cause late onset sepsis…
- Conditions
- Sepsis, Length of Stay, Mortality, Neurodevelopmental Delay
- Trial name
- LET-FEED (NCT06893939)
- Testing
- Limited Trophic Feeds (1 day of trophic feeds), Extended Trophic Feeds (3 days of trophics)
- Where
- 6 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Washington