Clinical trials: Labour;Obstructed
Postpartum Hemorrhage
Treatment of Postpartum Hemorrhage With Misoprostol: Fever Study
This study seeks to assess whether populations of women in Latin America outside Quito, Ecuador are at increased risk for developing elevated body temperature above 40.0°C following PPH treatment with 800mcg sublingual…
- Trial name
- NCT02163616
- Testing
- Misoprostol
- Where
- 2 sites in Argentina
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Gestational Diabetes Mellitus in Pregnancy, Macrosomia, Fetal
Late Gestational Diabetes Mellitus Diagnosis in Obese Women
In the current work, we aim to perform a prospective study that will investigate the relationship between maternal obesity (BMI >30 kg/m2) and morbid obesity (BMI >35 kg/m2) with a late GDM diagnosis (>32 weeks), with an emphasis…
- Conditions
- Gestational Diabetes Mellitus in Pregnancy, Macrosomia, Fetal, Dystocia, Shoulder, Neonatal Jaundice
- Trial name
- NCT05510518
- Testing
- oral glucose tolerance test (OGTT)
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Western Galilee Hospital-Nahariya
Birth; Prolonged
Acceptability Assessment of an Optimized Birthing Position
This qualitative study evaluates the acceptability of positioning pregnant women in labour in an optimized position, which consists in the hyperflexion of the legs and the loss of the lumbar lordosis.
- Trial name
- NCT04056793
- Testing
- Optimized birthing position
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Prolonged Labour
Can Ultrasound Predict Labor Outcome in Operative Vaginal Deliveries?
To assess whether ultrasound methods can predict outcome of operative vaginal deliveries in nulliparous women at term with singleton pregnancies and prolonged second stage of labor.
- Trial name
- NCT01878591
- Where
- Norway
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Uterine Atony, Uterine Tone Disorders
Intravenous Versus Intramuscular Administration of Methylergonovine for Uterine Contraction in Cesarean Sections
Insufficient uterine tone resulting in atony can potentiate hemorrhage and adverse outcomes for the parturient. Oxytocin is the first pharmacologic agent used, followed by methylergonovine, carboprost, and misoprostol.
- Conditions
- Uterine Atony, Uterine Tone Disorders, Postpartum Hemorrhage
- Trial name
- NCT03303235
- Testing
- Methylergonovine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Primary Postpartum Haemorrhage
Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja.
Postpartum haemorrhage is the leading cause of maternal haemorrhage globally. With active management of labour 3 to 16.5% of parturients still experience postpartum haemorrhage.
- Trial name
- NCT02424201
- Testing
- Misoprostol, vitamin c
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- Lagos State University
Labour Dystocia
Oral Sodium Bicarbonate for the Prevention of Labour Dystocia
Sodium bicarbonate is often used by athletes to improve their muscle's ability to contract and power their activity. It works by decreasing the risk of lactic acid build-up, which causes cramping and fatigue.
- Trial name
- Labour-Aide (NCT06249061)
- Testing
- oral sodium bicarbonate
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Liz Darling
Delivery Problem, Cervix; Pregnancy
Effects of Systematic Cervical Exam Training on Labor and Delivery Care
All physicians, nurses, and nurse midwives working on Labor and Delivery will be required to complete cervical exam simulation training.
- Conditions
- Delivery Problem, Cervix; Pregnancy, Pregnancy Related
- Trial name
- NCT04421768
- Testing
- cervical exam training
- Where
- United States
- Volunteers
- 1,125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Arrested Labor
Bicarbonate Given During Dystocic Labor
Dystocic deliveries and the use of bicarbonate
- Trial name
- NCT02805387
- Testing
- Treatment
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Pregnancy
Relevance of Ultrasound Screening for Foetal Macrosomia
Management of fetal macrosomia is based on a suspicion of macrosomia (no certainty before birth). This management is an artificial induction of labour for an earlier delivery and therefore a lower fetal weight gain.
- Trial name
- USmacro (NCT04443205)
- Testing
- Data record
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- CHU de Reims
Labor Stage, First, Prolonged Labor
Maternal Maneuvers During Prolonged Labor
This pilot, randomized control trial will test whether or not a specific circuit of position changes improves maternal outcomes in cases of prolonged labor.
- Trial name
- CIRCUIT (NCT06636149)
- Testing
- Circuit of maternal position changes during labor
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Washington University School of Medicine
Gestational Diabetes
Role of HbA1c in Predicting Adverse Pregnancy Outcomes
This study aims to determine the reference value of HbA1c that can be used to predict adverse pregnancy outcomes. These adverse outcomes include LGA fetus, shoulder dystocia, caesarean section, pre-term birth, pre-eclampsia and…
- Trial name
- NCT06676254
- Where
- Malaysia
- Volunteers
- 195 people
- Sponsor
- National University of Malaysia
Shoulder Dystocia - Delivered, Birth Disorder
Learning Skills in Shoulder Dystocia Delivery Using Simulator Models
Learning skills on shoulder dystocia on doctor and midwife
- Trial name
- NCT05921045
- Testing
- modification of clinical approach in clinical practice at time 0, modification of clinical approach in clinical practice at 6 months
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Obstructed Labor at Second Stage of Labor
Reverse Breech Extraction Versus Push Technique for Fetal Delivery When Fetal Head is Deeply Impacted in the Pelvis During CS on A Fully Dilated Cervix
Management of impacted fetal head during second stage cesarean requires careful and gentle attention to various surgical steps for delivery of a fetus without adverse maternal and neonatal outcomes, mostly by an experienced…
- Trial name
- NCT05707650
- Testing
- reverse breech extraction technique or push technique
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Orthopedic Disorder, Thoracic
Epidemiological Data on Pain
The ALGOBASES project is an observational epidemiological study of pain through the collection of pain evaluation questionnaires and information with the aim of creating a descriptive "pain" evaluation in all patients who need to…
- Conditions
- Orthopedic Disorder, Thoracic, Gynecological; Surgery (Previous), Causing Obstructed Labor, Affecting Fetus, Pain
- Trial name
- ALGOBASES (NCT04546594)
- Sponsor
- University Hospital, Lille
Cesarean Section, Dystocia
The REDUCED Trial: REDucing the Utilization of CEsarean Sections for Dystocia
This project is a clustered randomized controlled trial of a knowledge translation intervention of new ACOG guidelines for the diagnosis of poor progress in labor.
- Trial name
- REDUCED (NCT02874443)
- Testing
- Knowledge Translation of labor management guidelines
- Where
- Canada
- Volunteers
- 88,918 people
- Sponsor
- University of Calgary
Uterine Bleeding, Atony, Uterine
Questionnaire for Obstetricians and Anesthesiologist
The research was planned as a face-to-face survey evaluation. The questionnaire will be applied to obstetricians and anesthesiologists working in public and private hospitals.
- Conditions
- Uterine Bleeding, Atony, Uterine, Cesarean Section Complications
- Trial name
- NCT05089721
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Gazi University
Postpartum Hemorrhage
Fever After Misoprostol Administration for the Treatment of Primary Postpartum Hemorrhage
This study will evaluate side effects after sublingual misoprostol (600 mcg) as a first-line treatment for primary postpartum hemorrhage (PPH) due to suspected uterine atony.
- Trial name
- NCT01080846
- Testing
- Misoprostol
- Where
- Ecuador
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Uterine Atony, Postpartum Hemorrhage
An Evidence Based Protocol for Oxytocin Administration in Vaginal Delivery
The purpose of this study will be to evaluate a standardized, evidence-based protocol versus a conventional approach for the dosing of oxytocin in vaginal delivery.
- Trial name
- NCT02410655
- Testing
- Oxytocin
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Shoulder Dystocia Training Using AI-supported Flipped Learning in Midwifery Education
Evalution of the Effectiveness of a Shoulder Dystocia Training Program Designed With Inverted Learning Supported by Generative Artificial Intelligence
With the ongoing digital transformation in health education, the importance of learner-centered and technology-integrated approaches has been increasing.
- Trial name
- NCT07514702
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University