Clinical trials: Lactobacillus Infection
Gastrointestinal System Disease, Respiratory System
Probiotics Prevent Health Problems in Children
Randomized controlled field trial of a probiotics to assess its roles in the prevention or improvement of constipation and diarrhea, acute respiratory infection, nutrition improving in Vietnam children.
- Trial name
- Shirota (NCT04346576)
- Testing
- Probiotics prevent health problems in children
- Where
- Vietnam
- Volunteers
- 1,036 people, healthy volunteers welcome
- Sponsor
- National Institute of Nutrition, Vietnam
Recurrent Respiratory Tract Infections
Evaluation of Lactobacillus Reuteri DSM 17938 + Vitamin D3 in the Prevention of RRI in Paediatric Patients
The aim of this protocol is to evaluate, in a multicenter, randomized, double blind vs placebo clinical trial the effects of a marketed food supplement containing Lactobacillus reuteri DSM 17938 and vitamin D3 (Reuterin® D3) in…
- Trial name
- LR_D3 (NCT04408443)
- Testing
- Lactobacillus reuteri DSM 17938 + Vitamine D3
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Noos S.r.l.
Death, Nosocomial Infection
Prophylactic Probiotics in Premature Infants
This study tries to determine whether the oral administration of a specific probiotic (good bacteria) in premature infants hospitalized in a neonatal intensive care unit may prevent infections and the development of a severe…
- Trial name
- C3P (NCT00727363)
- Testing
- Lactobacillus reuteri
- Where
- 8 sites in Colombia
- Volunteers
- 751 people, healthy volunteers welcome
- Sponsor
- Colombian Neonatal Research Network
Bacterial Vaginosis (BV), Menopause
Probiotic Efficacy in Postmenopausal Women with Bacterial Vaginosis
This study is a double-blind, randomized, controlled trial (RCT) aimed at evaluating the effects of Lactobacillus sp. probiotic administration on the vaginal microbiota changes in postmenopausal women with bacterial vaginosis and…
- Trial name
- NCT06659380
- Testing
- Metronidazole + Floragyn® probiotic tablets (Lapi, Indonesia), Metronidazole + Cal95, Floragyn® probiotic tablets (Lapi, Indonesia)
- Where
- Indonesia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Upper Respiratory Tract Infections, Gastrointestinal Infection
Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children
this is a double-blind randomized placebo controlled clinical trial. 200 healthy children aged 12-48 months, attending day care or preschool for at least 5 days a week, regularly checked by the family pediatrician (FP) involved…
- Conditions
- Upper Respiratory Tract Infections, Gastrointestinal Infection, Children, Only
- Trial name
- FERCT19 (NCT05484102)
- Testing
- milk fermented with lactobacillus paracasei CBA L74
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bari
Infectious Diseases
Severe Necrotizing Enterocolitis in Preterm Newborns <1500g Using Probiotics
The purpose of this study is to know the effects of probiotics on the incidence of Necrotizing Enterocolitis (NEC) in preterm infants less than 1500 g.
- Trial name
- EPP (NCT02226263)
- Testing
- probiotics Lactobacillus acidophilus boucardii
- Where
- Mexico
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Dental Caries, Gingivitis
Anticaries Effect of Probiotic Lactobacillus Brevis CD2 (Lb CD2).
In a previous study the efficacy of Lb CD2 on interim covariates related to caries development was tested. So, it was decided to plan a new study on schoolchildren from the same area.
- Trial name
- NCT01778699
- Testing
- lozenges
- Where
- Italy
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Upper Respiratory Infection, Acute Otitis Media
Lactobacillus Rhamnosus GG in the Middle Ear and Adenoid Tonsil
The purpose of this study is to evaluate the effect of oral administration of probiotic Lactobacillus rhamnosus GG in middle ear and adenoid tonsil.
- Trial name
- NCT02110732
- Testing
- Lactobacillus rhamnosus GG
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Helsinki University Central Hospital
Feeding; Difficult, Newborn, Growth Failure
Prophylactic Probiotics to Extremely Low Birth Weight Prematures
Mortality and incidence of severe complications is still high among extremely premature infants. Common causes of severe complications in this population are poor nutrition, necrotizing enterocolitis, and severe infections.
- Conditions
- Feeding; Difficult, Newborn, Growth Failure, Necrotizing Enterocolitis, Sepsis
- Trial name
- PROPEL (NCT01603368)
- Testing
- Lactobacillus reuteri
- Where
- 2 sites in Sweden
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Ostergotland County Council, Sweden
Incidence of Infectious Diseases
Effect of a Follow on Formula With Lactobacillus Fermentum on the Incidence of Infections
The objective of the study is to evaluate the effects of a follow on formula containing the human milk probiotic Lactobacillus fermentum on the incidence of infection in 6 months old infants.
- Trial name
- NCT01215656
- Testing
- Lactobacillus fermentum, Follow on formula without probiotics
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Puleva Biotech
Gingivitis, Dental Plaque Accumulation
Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts.
The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque.
- Trial name
- NCT01236950
- Testing
- Essential oils mouthrinse, Delmopinol mouthrinse
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Healthy
Evaluation of Probiotics on Symptoms of Upper Respiratory Tract Infections
The aim of the present prospective study is to investigate whether the consumption of certain probiotic strains over a six-month winter/spring season would be able to affect the incidence and duration of upper respiratory tract…
- Trial name
- NCT00599430
- Testing
- Lactobacillus acidophilus NCFM, Combination of Lactobacillus acidophilus and Bifidobacterium lactis
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Danisco
Infections, Upper Respiratory Tract
The Effect of a Probiotic on Upper Respiratory Tract Infections
This study is a randomized, double-blind, placebo-controlled, two-armed, parallel-group study in healthy children aged 2-6 years.
- Trial name
- PIP-U (NCT03636191)
- Testing
- Probiotic strain
- Where
- United Kingdom
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Caesarean Section;Stillbirth, Microbial Colonization
Lactobacillus Kefiri LKF01 (DSM32079) in Newborns Born by Caesarian Section
The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life.
- Trial name
- NCT03154866
- Testing
- Lactobacillus kefiri LKF01 DSM32079
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Infection
Safety Assessment of Lactobacillus Salivarius CECT5713 in 6 Months Old Children
The aim of the trial is to evaluate safety of a follow on formula supplemented with Lactobacillus salivarius CECT5713. A randomized double blind placebo controlled trial was carried out.
- Trial name
- P010 (NCT00724204)
- Testing
- follow on formula without probiotics, follow on formula with Lactobacillus salivarius CECT5713
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Puleva Biotech
Infectious Diseases
Prevention of Necrotizing Enterocolitis of Premature Newborns Under Less Than 1500 g Using Probiotics
The purpose of this study is to evaluate the incidence of necrotizing enterocolitis and its effect over the secreting immunoglobulin A in the feces with the use of probiotics of the strain Lactobacillus acidophilus boucardii vs.
- Trial name
- (PEPP) (NCT02245815)
- Testing
- use probiotics boucardii, use probiotics Multi-species
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Respiratory Tract Infections, Diarrhea
Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) in Uganda
This is a nutritional trial with two arms: 1) Intervention arm of Probiotic Yoghurt containing Lactobacillus rhamnosus yoba 2012 and 2) Control arm of custard-like dairy product.
- Conditions
- Respiratory Tract Infections, Diarrhea, Skin Diseases, Tinea Capitis
- Trial name
- NCT04144491
- Testing
- Probiotic
- Where
- Uganda
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Common Infectious Diseases
Effect of the Consumption of a Fermented Milk on Common Infections in Children Aged 3-6 Years, Attending Day Care Centers
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Trial name
- NCT01200173
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- Russia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Healthy Infants
Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants
Randomized, doble blind, clinical, controlled trial aimed to investigate the role of Lactobacillus reuteri DSM 17938 in the prevention of gastrointestinal and respiratory tract infections in mexican children who attend day care…
- Trial name
- NCT01249911
- Testing
- Lreuteri
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- National Institute of Pediatrics, Mexico
Microbiome
Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19
The purpose of this study is to evaluate the effect of the probiotic Lactobacillus rhamnosus GG (LGG) and the effect of COVID-19 on the microbiome (the microorganisms that live in and on the human body) in exposed household…
- Trial name
- NCT04399252
- Testing
- Lactobacillus rhamnosus GG
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Duke University