Clinical trials: Lactobacillus Infection
Very Low Birth Weight Infants
Comparison of Lactobacillus Reuteri and Nystatin Prophylaxis on Candida Colonization and Infection in Very Low Birth Weight Infants
Probiotics are favorable microorganisms that regulate the flora of the gastrointestinal system and stimulate the immune system. Lactobacillus reuteri was shown to reduce candida colonization.
- Trial name
- NCT01531192
- Testing
- Lactobacillus reuteri, Nystatin
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Gingivitis, Dental Plaque Accumulation
Study of an Essential Oil and a Delmopinol Mouthrinse Effect on Dental Plaque Accumulation Index, Gingivitis Index and on Streptococcus Mutans, Lactobacillus, Aerobic and Anaerobic Oral Bacteria Colony Counts.
The use of mouthrinses may be of relevance as a complement to daily dental hygiene procedures, especially for patients who do not comply with a proper mechanical removal of dental plaque.
- Trial name
- NCT01236950
- Testing
- Essential oils mouthrinse, Delmopinol mouthrinse
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Infectious Diarrhea, Acute Gastroenteritis
Lactobacillus Acidophilus and Limosilactobacillus Reuteri for Acute Diarrhea in Children
This randomized controlled trial evaluated the effect of a combination of Lactobacillus acidophilus DSMZ 26280 and Limosilactobacillus reuteri DSMZ 25441 on the duration of diarrhea and gut microbiota composition in children aged…
- Trial name
- NCT07342088
- Testing
- Probiotic, Standard therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people
- Sponsor
- Eskisehir Osmangazi University
Gingivitis
Clinical Effect of Lactobacillus Reuteri in Treatment of Gingivitis
The aim of this randomized placebo- controlled clinical trials is to evaluate the effects of Lactobacillus reuteri containing probiotic lozenges as an adjunct to scaling and root planning (SRP).
- Trial name
- NCT02801773
- Testing
- Treatment Gingivitis with Probiotic, Treatment Gingivitis conventional
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Plaque Ph Lowering After Use of Probiotics, Caries
Effect of Probiotic on the Plaque pH. A Randomized Double Blind Interventional Study
The aim of the present research protocol was to evaluate the effect of probiotics daily used, on the plaque acidogenicity of children.
- Conditions
- Plaque Ph Lowering After Use of Probiotics, Caries, Gingivitis
- Trial name
- NCT01601145
- Testing
- consumption of lozenges
- Where
- Italy
- Volunteers
- 192 people
- Sponsor
- Università degli Studi di Sassari
Bacteriuria
Bacteriuria Eradication Through Probiotics
Many children who catheterize their bladders because of spina bifida or other neurologic disorders have bacteriuria. This can lead to urinary tract infections by bacteria from the gut which colonize the vagina and are carried…
- Trial name
- BERP (NCT00717600)
- Testing
- Lactobacillus reuteri RC-14 and Lactobacillus rhamnosus GR-1
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine
Healthy
Evaluation of Probiotics on Symptoms of Upper Respiratory Tract Infections
The aim of the present prospective study is to investigate whether the consumption of certain probiotic strains over a six-month winter/spring season would be able to affect the incidence and duration of upper respiratory tract…
- Trial name
- NCT00599430
- Testing
- Lactobacillus acidophilus NCFM, Combination of Lactobacillus acidophilus and Bifidobacterium lactis
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Danisco
Infections, Upper Respiratory Tract
The Effect of a Probiotic on Upper Respiratory Tract Infections
This study is a randomized, double-blind, placebo-controlled, two-armed, parallel-group study in healthy children aged 2-6 years.
- Trial name
- PIP-U (NCT03636191)
- Testing
- Probiotic strain
- Where
- United Kingdom
- Volunteers
- 619 people, healthy volunteers welcome
- Sponsor
- Chr Hansen
Caesarean Section;Stillbirth, Microbial Colonization
Lactobacillus Kefiri LKF01 (DSM32079) in Newborns Born by Caesarian Section
The mode of delivery affects the diversity and colonization pattern of the gut microbiota during the first year of infants' life.
- Trial name
- NCT03154866
- Testing
- Lactobacillus kefiri LKF01 DSM32079
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Infection
Safety Assessment of Lactobacillus Salivarius CECT5713 in 6 Months Old Children
The aim of the trial is to evaluate safety of a follow on formula supplemented with Lactobacillus salivarius CECT5713. A randomized double blind placebo controlled trial was carried out.
- Trial name
- P010 (NCT00724204)
- Testing
- follow on formula without probiotics, follow on formula with Lactobacillus salivarius CECT5713
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Puleva Biotech
Gingivitis
Clinical and Microbiological Effects of Lactobacillus Rhamnosus in Treatment of Gingivitis
The aim of this randomized placebo- controlled clinical trial is to evaluate the effects of Lactobacillus rhamnosus SP1- containing probiotic sachet as an adjunct to scaling and root planning (SRP).
- Trial name
- NCT02809313
- Testing
- Treatment Gingivitis with Probiotic, Treatment Gingivitis conventional
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Jorge Gamonal
Infectious Diseases
Prevention of Necrotizing Enterocolitis of Premature Newborns Under Less Than 1500 g Using Probiotics
The purpose of this study is to evaluate the incidence of necrotizing enterocolitis and its effect over the secreting immunoglobulin A in the feces with the use of probiotics of the strain Lactobacillus acidophilus boucardii vs.
- Trial name
- (PEPP) (NCT02245815)
- Testing
- use probiotics boucardii, use probiotics Multi-species
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Upper Respiratory Tract Infection
Probiotic Supplementation in Children Affected by Upper Respiratory Infections
The goal of this randomized non-pharmacological Intervention study is to evaluate the effects of probiotic supplements (Bifidobacterium breve M-16V, Bifidobacterium lactis HN019, Lactobacillus rhamnosus HN001) on children…
- Trial name
- PROBIOS2021 (NCT06052540)
- Testing
- Probiotic supplement
- Where
- Italy
- Volunteers
- 128 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Respiratory Tract Infections, Diarrhea
Effect of L. Rhamnosus Yoba on RTI and Other Health Outcomes Among Children (3-6 Years) in Uganda
This is a nutritional trial with two arms: 1) Intervention arm of Probiotic Yoghurt containing Lactobacillus rhamnosus yoba 2012 and 2) Control arm of custard-like dairy product.
- Conditions
- Respiratory Tract Infections, Diarrhea, Skin Diseases, Tinea Capitis
- Trial name
- NCT04144491
- Testing
- Probiotic
- Where
- Uganda
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Febrile Neutropenia, Neutropenia
Prevention of Febrile Neutropenia by Synbiotics in Pediatric Cancer Patients
Febrile neutropenia (FN) is a major life-threatening treatment complication in cancer patients undergoing intensive chemotherapy. Endogenous flora is considered to be one of the main sources of infections during neutropenia.
- Conditions
- Febrile Neutropenia, Neutropenia, Infection in an Immunocompromised Host, Cancer
- Trial name
- FENSY (NCT02544685)
- Testing
- Probio-Fix Inum, Beneo Synergy 1
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- S&D Pharma SK s.r.o.
C-section
Lactobacillus Reuteri DSM17938 in C-Section Infants
RCT designed to evaluate the impact of Lactobacillus reuteri DSM17938 to modify gut microbiota in children delivered by C-section
- Trial name
- NCT03834415
- Testing
- Lactobacillus reuteri DSM17038
- Where
- Mexico
- Volunteers
- 69 people
- Sponsor
- Innovacion y Desarrollo de Estrategias en Salud
Common Infectious Diseases
Effect of the Consumption of a Fermented Milk on Common Infections in Children Aged 3-6 Years, Attending Day Care Centers
This multicentric, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Trial name
- NCT01200173
- Testing
- 1-Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), 2-Non fermented dairy product (control)
- Where
- Russia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Healthy Infants
Lactobacillus Reuteri DSM 17938 and Prevention of Respiratory and Gastrointestinal Infections in Mexican Infants
Randomized, doble blind, clinical, controlled trial aimed to investigate the role of Lactobacillus reuteri DSM 17938 in the prevention of gastrointestinal and respiratory tract infections in mexican children who attend day care…
- Trial name
- NCT01249911
- Testing
- Lreuteri
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- National Institute of Pediatrics, Mexico
Microbiome
Effect of Lactobacillus on the Microbiome of Household Contacts Exposed to COVID-19
The purpose of this study is to evaluate the effect of the probiotic Lactobacillus rhamnosus GG (LGG) and the effect of COVID-19 on the microbiome (the microorganisms that live in and on the human body) in exposed household…
- Trial name
- NCT04399252
- Testing
- Lactobacillus rhamnosus GG
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Duke University
Pulmonary Inflammation, Cystic Fibrosis
Modulation of Intestinal and Pulmonary Inflammation by Lactobacillus Diet Supplementation in Pediatric Cystic Fibrosis
Pulmonary inflammation is an independent risk factor for disease progression in cystic fibrosis patients (CF). Yet, no effective treatment is known to reduce this detrimental inflammation.
- Conditions
- Pulmonary Inflammation, Cystic Fibrosis, Microbiota
- Trial name
- MoHuM-1 (NCT01837355)
- Testing
- Lactobacillus rhamnosus
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Cantonal Hospital of St. Gallen