Clinical trials: Language
Primary Progressive Aphasia, Semantic Dementia
Primary Progressive Aphasia Multicomponent Language Treatment Study
The goal of this clinical trial is to learn if a speech-language telerehabilitation helps improve communication in people with primary progressive aphasia (PPA), a form of dementia that affects speech and language.
- Conditions
- Primary Progressive Aphasia, Semantic Dementia, Semantic Memory Disorder, Logopenic Progressive Aphasia
- Trial name
- NCT06649084
- Testing
- Multicomponent Lexical Retrieval Training (Multi-LRT), Multicomponent Video Implemented Script Training in Aphasia (Multi-VISTA), Multicomponent Communication Partner Training (Multi-CPT)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Texas at Austin
Infectious Disease
Lao Anti-Microbial Prescribing Guidelines Mobile Phone Application (LAMPA)
The overall aim of this study is to compare the proportion of antimicrobial prescriptions adherent with prescribing guidelines delivered by mobile phone application (app) versus paper-based prescribing guidelines in both in- and…
- Trial name
- LAMPA (NCT04914793)
- Testing
- Antimicrobial prescribing guideline mobile phone application (MicroGuide)
- Where
- Laos
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Lao-Oxford-Mahosot Hospital Wellcome Trust Research Unit
Feeding and Eating Disorders of Childhood
Italian Language Validation of The Eating Disorder Examination (EDE) - Child Version
Although eating disorders often occur during or after puberty, it is likely that critical antecedent conditions can be established before adolescence.
- Trial name
- NCT06286852
- Testing
- Administration of K-SADS-PL- Kiddie-Schedule for Affective Disorder and Schizophrenia-Present and Lifetime version (Kaufmann, 2002), Administration of ChEDE- Child Version of the EatingDisorder Examination
- Where
- 3 sites in Italy
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Meyer Children's Hospital IRCCS
Cerebral Palsy, Spasticity
Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy
The aim of our work is to investigate whether electrical Lateral Cord Stimulation (LCS) causes an inhibitory and modulatory action by indirect cerebellar activation, so releasing spasticity and the spastic syndrome in selected…
- Trial name
- Andreani1 (NCT02199015)
- Testing
- Lateral spinal cord surgical implant of electrodes
- Where
- 2 sites in Argentina, Germany
- Volunteers
- 40 people
- Sponsor
- Juan Carlos M. Andreani MD
Mouth Breathing
The Influence of Breathing in Writing
Purpose: To examine whether nasal breathing influences the perception of sound causing trade between hard and soft consonants in the writing of children in school age and the incidence of trade.
- Trial name
- NCT02437877
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dyslexia, Dyslexia, Developmental
Impact of Non-invasive Brain Stimulation on Learning Novel Spoken Words
The purpose of the proposed study is to use transcranial magnetic stimulation (TMS) to evaluate a neurobiological model of spoken word learning in older youth.
- Conditions
- Dyslexia, Dyslexia, Developmental, Learning; Developmental Disorder, Reading
- Trial name
- NCT06387615
- Testing
- Active cTBS
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Language Disorders
Partial Word Knowledge Growth in Children With LLD
Children with language-learning disabilities (LLD) have language and reading skills that are weaker than those of typically developing children.
- Trial name
- NCT00547833
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Dyslexia, Visual Attention Span Deficit
Visual Attention Span Mobilisation for Dyslexia
The aim of the study is to evaluate the efficiency of the medical device MAEVAD in improving the reading skills of children with dyslexia.
- Trial name
- NCT05201235
- Testing
- MAEVAD, DeCaLigne
- Where
- 55 sites in France
- Volunteers
- 74 people
- Sponsor
- Humans Matter
Down Syndrome, Cerebral Palsy
Measuring Aided Language Development
The focus of the current study is to systematically investigate the psychometric properties of a range of aided language measures, which are based on the Graphic Symbol Utterance and Sentence Development Framework (Binger \&…
- Conditions
- Down Syndrome, Cerebral Palsy, Apraxia of Speech, Speech Sound Disorder
- Trial name
- MALD (NCT06512168)
- Testing
- AAC Generative Language Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Central Florida
Autism
Project VOICES: Vocal Optimization in Children Elevating the Spectrum
Thirty percent of children with autism barely talk or do not talk at all despite years of intervention. This study aims to address this important and long-standing challenge by developing a novel intervention to increase the…
- Trial name
- Project VOICES (NCT06875843)
- Testing
- Contingent responses, Contingent responses plus vocal elicitation strategies, Non-contingent control
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center
Chatbot, Large Language Model
Effects of a Large Language Model-Driven Chatbot on Reproductive Concerns After Cancer
Reproductive health has emerged as a critical yet overlooked concern among Adolescent and Young Adult (AYA) cancer survivors, given their compromised potential for biological parenthood in prime childbearing years.
- Conditions
- Chatbot, Large Language Model, Adolescent and Young Adult Cancer Survivors, Reproductive Health
- Trial name
- NCT07741266
- Testing
- Chatbot, Electronic brochure
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Brain Tumor
Use of Navigated Transcranial Magnetic Stimulation (nTMS) in Generated Motor and Language Mapping to Evaluate Brain Recovery Following Surgery
The goal of this clinical research study is to learn about using Navigated Transcranial Magnetic Stimulation (nTMS) in patients having surgery to remove a brain tumor in areas of the brain that control movement (motor function)…
- Trial name
- NCT02165995
- Testing
- Motor Mapping, Speech Mapping
- Sponsor
- M.D. Anderson Cancer Center
Autism Spectrum Disorder, Language Development
HR-EEG Contribution in Prognostic Evaluation of Language Development in Children With ASD
The goal of this prospective observational multicentric cohort study is to evaluate the clinical prognostic value of the speech tracking score of language development in children with ASD aged from 3 years to 4 years and half at…
- Conditions
- Autism Spectrum Disorder, Language Development, Neurocognitive Disorders, Child Language
- Trial name
- EE-TSA-LANG (NCT05586672)
- Testing
- EEG-HR, ADI-R, ADOS-2
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de Santé Barthélemy Durand
Obsessive-compulsive Disorder, Social Phobia
Brief Behavioral Treatment for Anxiety in Young Children
Behaviorally and cognitive-behaviorally based therapeutic techniques (BT; CBT) that incorporate exposure therapy useful for treatment of anxiety disorders among typically developing children.
- Conditions
- Obsessive-compulsive Disorder, Social Phobia, Generalized Anxiety Disorder, Specific Phobia
- Trial name
- PLET (NCT02051192)
- Testing
- Parent-Led Exposure Therapy, Treatment As Usual
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of South Florida
Developmental Dyslexia
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT05832060
- Testing
- Active tDCS, Active tRNS
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Dyslexia
Static and Dynamic Balance in Children With Dyslexia
Dyslexia is described as a learning disability with a neurological origin. It is a widespread disease, characterized by difficulties in recognition of words, spelling, and decoding.
- Trial name
- NCT04386161
- Testing
- Scheduled exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Marmara University
Speech Sound Disorder
Effectiveness of Ultrasound-Aided Articulation Therapy for Children With Speech Sound Disorders
This prospective randomized controlled trial investigates the effect of ultrasound visual biofeedback as an adjunct to articulation therapy in children with speech sound disorders involving lingual targets.
- Trial name
- NCT06831396
- Testing
- Ultrasound-aided articulation therapy
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Language Development
Language Environment in Children With Cochlear Implants
The Language Environment Analysis (LENA) system is a specific tool for the language environment analysis. Children aged from 18 months to 6 years old, with cochlear implants (CIs), wear an electronic device during a day and their…
- Trial name
- ISLODA (NCT02853786)
- Testing
- LENA and advice, LENA without advice
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Stammering
Comparison of Pantomiming and Easy Onset Treatment
This research will give in-depth understanding of pantomiming and easy onset method as an intervention of stuttering and especially blocking.
- Trial name
- NCT04813588
- Testing
- Pantomiming, Easy onset
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Speech Impairment
Software for Alternative Communication
The aim of this study is evaluate a software developed for alternative communication designed for people with speech difficulties.
- Trial name
- NCT02847923
- Testing
- Presentation of alternative communication application, Familiarization with the software interface, Test of the software
- Where
- 2 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- University of Mogi das Cruzes