Clinical trials: Language
Dyslexia, Developmental
Neural Mechanisms of Successful Intervention in Children With Dyslexia
Dyslexia, an impairment in accurate or fluent word recognition, is the most common learning disability affecting roughly ten percent of children.
- Trial name
- NCT04323488
- Testing
- Lindamood-Bell Seeing Stars
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Stanford University
Development Language Disorder
Promoting Motivation and Linguage in Developmental Language Disorder Through Interaction With the Humanoid Social Robot
Developmental Language Disorder (DLD) is a communication disorder that interferes with learning, understanding, and using language.
- Trial name
- NCT07426328
- Testing
- Nao assisted therapy, Standard therapeutic protocol
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS Centro Neurolesi Bonino Pulejo
Autism Spectrum Disorder, Developmental Language Disorder
Efficacy of a Pragmatic Intervention to Improve Adaptation to Context and Interlocutor
Patients with Developmental Language Disorder (DLD) or Autism Spectrum Disorder (ASD) have communicational difficulties to adapt their language to context and to interlocutors.
- Trial name
- NCT05127863
- Testing
- social communication intervention (pragmatic)
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- Université Catholique de Louvain
Parkinson's Disease, Deep Brain Stimulation
Can Subthalamic Stimulation Using Directional Electrodes Improve Postoperative Management in Parkinson's Disease
The primary objective of the study is to determine if subthalamic nucleus (STN) deep brain stimulation (DBS) using the Vercise directional leads improves neuropsychiatric state and neuropsychiatric fluctuations 12 months after…
- Trial name
- Steeropt (NCT04578678)
- Testing
- Steering
- Where
- 4 sites in France, Germany and 1 more
- Volunteers
- 105 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Fabry Disease
Early Detection of Fabry Disease
The main aim of this study is early detection of FD using real-world data for the development of advanced natural language processing methods and to develop a predictive algorithm and to measure the performance of the algorithm…
- Trial name
- NCT05106764
- Testing
- No intervention
- Where
- 3 sites in Germany
- Volunteers
- 50 people
- Sponsor
- Takeda
Developmental Language Disorder
Maximizing Outcomes for Preschoolers With Developmental Language Disorders
The objective of the proposed study is to evaluate the efficacy of the Enhanced Milieu Teaching-Sentence Focus (EMT-SF) intervention, implemented by caregivers and interventionists, relative to a control condition enrolling 108…
- Trial name
- NCT03782493
- Testing
- the Enhanced Milieu Teaching-Sentence Focus
- Where
- 2 sites in United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Developmental Dyslexia, Developmental Language Disorder
Dynamic Assessment of the Risk for Language and Reading Disorders in Monolingual and Multilingual Children
The project represents the completion of a part of the recently concluded European project MultiMind, in which a computer platform called MuLiMi was developed and validated.
- Trial name
- NCT06937255
- Testing
- computerized Dynamic Assessment
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Specific Language and Learning Disorders (SLLD)
Study of the Value of Trio Exome Sequencing in the Etiological Assessment of Specific Non-syndromic Language and Learning Disorders
Specific language and learning disorders (SLLD) affect around 5-10% of school-aged children, or 1-2 child(ren) per class. SLLDs correspond to the impairment of a specific cognitive function and are divided into 5 categories…
- Trial name
- TSLA ES (NCT05939739)
- Testing
- Blood samples, Consultation for results delivery, Study Humanities and Social Sciences
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Spinal Muscular Atrophy 1
Exploring Lived Experiences of Families of Children With Spinal Muscular Atrophy(SMA) Type 1 Regarding Feeding and Communication
Spinal Muscular Atrophy Type 1 (SMA )Type 1 is a severe, early-onset neuromuscular condition that typically leads to profound weakness and impaired bulbar function-affecting swallowing, feeding, speech, and airway protection.
- Trial name
- NCT07596277
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
MLD, Krabbe Disease
Longitudinal Study of Neurodegenerative Disorders
The purpose of this study is to understand the course of rare genetic disorders that affect the brain. This data is being analyzed to gain a better understanding of the progression of the rare neurodegenerative disorders and the…
- Conditions
- MLD, Krabbe Disease, ALD, MPS I
- Trial name
- NCT03333200
- Testing
- Palliative Care, Hematopoetic Stem Cell Transplantation
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Pittsburgh
Language Development
Language Environment in Children With Cochlear Implants
The Language Environment Analysis (LENA) system is a specific tool for the language environment analysis. Children aged from 18 months to 6 years old, with cochlear implants (CIs), wear an electronic device during a day and their…
- Trial name
- ISLODA (NCT02853786)
- Testing
- LENA and advice, LENA without advice
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Dyslexia, Reading Disorder
Group-based Training for Parents of Children With Dyslexia
Children with dyslexia show a variety of comorbid disorders like behavior and adaptive disorders, hyperkinetic and anxiety disorders. Raising and educating a child with dyslexia is a challenging task for parents.
- Conditions
- Dyslexia, Reading Disorder, Reading Disability, Developmental Reading Disorder
- Trial name
- NCT02107534
- Testing
- parent training (dyslexia)
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University of Heidelberg Medical Center
Primary Progressive Aphasia, Neurodegenerative Diseases
Home-Based Exercise in Primary Progressive Aphasia (HEPPA)
This pilot study aims to evaluate the feasibility of a novel home-based multicomponent exercise program in adults clinically diagnosed with Primary Progressive Aphasia
- Conditions
- Primary Progressive Aphasia, Neurodegenerative Diseases, Logopenic Progressive Aphasia, Semantic Dementia
- Trial name
- HEPPA (NCT06181500)
- Testing
- Home-based multicomponent exercise intervention program
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- Montreal Heart Institute
Perinatal Condition, Neurodevelopmental Disorders
Perinatal and Psychological Correlates of Neurodevelopmental Disorders in Children.
The goal of this observational study is to investigate perinatal, cognitive and social-emotional correlates of neurodevelopmental disorders and educational difficulties in children and adolescents.
- Conditions
- Perinatal Condition, Neurodevelopmental Disorders, Social Functioning, Child Development
- Trial name
- NCT06215092
- Testing
- Psychological assessment
- Where
- Poland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Bartosz M. Radtke
Developmental Language Disorder
Learning in Children With Developmental Language Disorder
Developmental language disorder (DLD) is a condition that affects children's ability to learn and use language. These difficulties can affect communication, learning, and participation in everyday activities.
- Trial name
- NCT07899671
- Testing
- priming
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- MGH Institute of Health Professions
Orofacial Difficulties in Newborns, Maternal Breastfeeding in Newborns
Orofacial Difficulties in Rooming-in
The purpose of this study is to identify the orofacial difficulties during the maternal breastfeeding in rooming-in.
- Conditions
- Orofacial Difficulties in Newborns, Maternal Breastfeeding in Newborns, Newborns in Rooming-in
- Trial name
- AMAC (NCT01051843)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Fortaleza University
Dementia, Alzheimer Disease
Digital Interventions in Neuro-Rehabilitation: Gotcha!
Aims and background Everyone forgets the names of people they should know at times. Having dementia makes this problem worse. People with dementia have told expressed they forget the names of people they care about and this can…
- Conditions
- Dementia, Alzheimer Disease, Anomia
- Trial name
- NCT04570215
- Testing
- Gotcha! Therapy application, Gotcha Therapy application: Maintenance
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Fragile X Syndrome, Genetic Diseases
Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome
The purpose of the study is to test the efficacy of a 20 week multi-modal treatment comprised of lovastatin or placebo, and the Parent-implemented Language Intervention (PILI) in children with fragile X syndrome (FXS).
- Trial name
- NCT02642653
- Testing
- Lovastatin
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Davis
Language Disorder
Efficacy of AMALS in Treating Language Impairment in Children
The goal of this proposal is to examine the efficacy of a manualized treatment intervention, AMALS: Addressing Multiple Aspects of Language Simultaneously, which is designed to remediate semantic, morphological, and syntactic…
- Trial name
- AMALS (NCT00840060)
- Testing
- AMALS, DTA
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Lamar University
Cleft Palate Children
Effect of Infant Sign Training on Speech-language Development
Children born with a cleft lip and palate (CLP) are known to be at risk for speech-language disorders that impact academic and social emotional growth.
- Trial name
- NCT06143254
- Testing
- Infant sign training, Verbal training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent