Clinical trials: Language Disorder
Autism Spectrum Disorder
Stimulus-Stimulus Pairing Study
The purpose of the current study is to deliver the SSP procedure to children diagnosed with autism that do not have vocal language. The study will also aim to gather data in the natural environment using a voice recorder.
- Trial name
- NCT02464527
- Testing
- Stimulus-stimulus pairing, Vocal recorder
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Emory University
Allergic Reaction
Analysis of Adverse Events in Anesthesia Using Artificial Intelligence
The interest of health databases in anesthesia is no longer to be demonstrated. The aim of this research was to develop a natural language processing approach to establish a classification of adverse events observed during the…
- Trial name
- ADVENTURE (NCT05185479)
- Where
- France
- Volunteers
- 9,559 people
- Sponsor
- University Hospital, Strasbourg, France
Central Auditory Disease, Healthy
Testing a Possible Cause of Reduced Ability of Children to Process Speech in Noise
This study aims to increase our understanding of the difficulty people have recognizing the spoken word, especially in noisy situations.
- Trial name
- NCT00001957
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute on Deafness and Other Communication Disorders (NIDCD)
Specific Language and Learning Disorders (SLLD)
Study of the Value of Trio Exome Sequencing in the Etiological Assessment of Specific Non-syndromic Language and Learning Disorders
Specific language and learning disorders (SLLD) affect around 5-10% of school-aged children, or 1-2 child(ren) per class. SLLDs correspond to the impairment of a specific cognitive function and are divided into 5 categories…
- Trial name
- TSLA ES (NCT05939739)
- Testing
- Blood samples, Consultation for results delivery, Study Humanities and Social Sciences
- Where
- France
- Volunteers
- 101 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Language Development Disorders
The Effect of Semantic Support on Word Learning
The goal of this clinical trial is to compare word learning outcomes in late talking toddlers who are taught different types of words.
- Trial name
- NCT05921214
- Testing
- VAULT Phase 5
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Arizona
Developmental Language Disorder
Semantic Learning Deficits in School Age Children With Developmental Language Disorder
School age children with developmental language disorder (DLD) have known semantic learning deficits but what is less well understood is why semantic learning is difficult for these children.
- Trial name
- NCT04508699
- Testing
- semantic learning
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Benign Epilepsy With Centrotemporal Spikes, Language Problems
Transcranial Magnetic Stimulation for BECTS
Benign epilepsy with centrotemporal spikes (BECTS) is the most common pediatric epilepsy syndrome. Affected children typically have a mild seizure disorder, but yet have moderate difficulties with language, learning and attention…
- Conditions
- Benign Epilepsy With Centrotemporal Spikes, Language Problems, Learning Disorders
- Trial name
- TMS4BECTS (NCT04325282)
- Testing
- Active rTMS
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Autism, ADHD
Spanish-language Executive Function Intervention for Children With Autism and/or ADHD
The goal of this clinical trial is to learn whether the Spanish-language version of Unstuck and On Target (SL-Unstuck), an executive functioning (EF) intervention, is feasible, acceptable, and effective for Spanish-speaking…
- Trial name
- NCT07084324
- Testing
- Unstuck and On Target
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Down Syndrome
Symbolic Representation in Young Children With Down Syndrome
The aim of this study is to characterize the process of constitution of symbolic representation in infants with Down syndrome, as well as to investigate the relationship between gestures and the emergence of oral language.
- Trial name
- NCT00668980
- Where
- 3 sites in Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Speech Impairment
Software for Alternative Communication
The aim of this study is evaluate a software developed for alternative communication designed for people with speech difficulties.
- Trial name
- NCT02847923
- Testing
- Presentation of alternative communication application, Familiarization with the software interface, Test of the software
- Where
- 2 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- University of Mogi das Cruzes
Down Syndrome
Functional Communicative Profile of Children With Down Syndrome
The aim of this study was to verify the use of communicative functions by children with DS in two interaction conditions: interaction with therapist and interaction with parent.
- Trial name
- NCT00844259
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Autism Spectrum Disorder
Telehealth Language Intervention for Children With Autism Ages 2-4 Years
The main goal of this intervention is to increase caregivers' use of interactive play and communication strategies to improve the child's early sentence development using telemedicine and video-based feedback.
- Trial name
- NCT04675580
- Testing
- Toy Talk
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Weill Medical College of Cornell University
Severe to Profound Prelingual Hearing Loss
Language Development in Children With Cochlear Implants and Speech-language Therapy Interventions
Cochlear implantation is currently offered to children with severe to profound prelingual hearing loss for whom hearing aids alone are insufficient to provide access to oral language (HAS, 2009).
- Trial name
- ICORTHO (NCT07447427)
- Testing
- Speech-language therapy (observed standard care)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hay Fever, Asthma
Evaluating the Potential of Large Language Models for Respiratory Disease Consultations
The clinical trial aimes to evaluate multiple large language models in respiratory disease consultations by comparing their performance to that of human doctors across three major medical consultation scenarios.
- Conditions
- Hay Fever, Asthma, Acute Upper Respiratory Infection, Pulmonary Embolism
- Trial name
- EPLLMMRDC (NCT06457269)
- Testing
- Diagnosis by three human doctors, Diagnosis by ChatGPT-3.5 (with search capabilities), Diagnosis by ChatGPT-3.5 (without search capabilities)
- Where
- China
- Volunteers
- 703 people
- Sponsor
- North Sichuan Medical College
Cerebrovascular Disorder, Epilepsy
Brain Blood Flow Studies of Language and Memory
Positron Emission Tomography (PET) is a technique used to investigate the functional activity of the brain. The PET technique allows doctors to study the normal processes of the brain (central nervous system) of normal…
- Trial name
- NCT00001288
- Testing
- 15 O Water, FDG
- Where
- United States
- Volunteers
- 303 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Feeding and Eating Disorders
Italian Validation of the State Urge to be Physically Active- Questionnaire (SUPAQ-I) in Patients With Eating Disorders
Eating disorders (EDs) are severe psychiatric conditions that cause significant health and psychosocial issues, with Anorexia Nervosa (AN) and Bulimia Nervosa (BN) having the highest mortality rates.
- Trial name
- SUPAQ-I (NCT06514456)
- Testing
- no intervention
- Where
- Italy
- Volunteers
- 210 people
- Sponsor
- Istituto Auxologico Italiano
Language Impairment, Hearing Loss
Characterization of Auditory Processing Involved in the Encoding of Speech Sounds
The ability to encode the speech signal is determined by ascending and descending auditory processing. Difficulties in processing these speech signals are well described at the behavioral level in a specific language disorder.
- Trial name
- PRODIPRICIDE (NCT02574299)
- Testing
- E-learning, Hearing aids fitting
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Autism Spectrum Disorder
Evaluating the Efficacy of Pathways Parent-Mediated Early Autism Intervention on Social Attention and Language
The goal of this clinical trial is to compare the efficacy of Pathways parent-mediated early autism intervention (Pathways) and a parent education intervention (PEI) delivered to culturally and linguistically diverse families…
- Trial name
- NCT05604326
- Testing
- Pathways Intervention, Parent Education Intervention (PEI)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- The University of Texas at Dallas
Down Syndrome
Liq-NOL Efficacy in Pediatric Patients With Down Syndrome
The purpose of this study is to measure the effects of LiQ-NOL supplementation on language production using the Clinical Evaluation of Language Fundamentals test, language sampling using the mean length of utterance test, and…
- Trial name
- NCT00891917
- Testing
- Ubiquinol-10 Syrup
- Where
- United States
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Schizophrenia and Related Disorders
Linguistic Predictors of Outcomes in Psychosis
Longitudinal observational study of the relationship between speech patterns and clinical symptoms in schizophrenia spectrum disorders.
- Trial name
- LPOP (NCT05601050)
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Northwell Health