Clinical trials: Language Disorder
Autism
Project VOICES: Vocal Optimization in Children Elevating the Spectrum
Thirty percent of children with autism barely talk or do not talk at all despite years of intervention. This study aims to address this important and long-standing challenge by developing a novel intervention to increase the…
- Trial name
- Project VOICES (NCT06875843)
- Testing
- Contingent responses, Contingent responses plus vocal elicitation strategies, Non-contingent control
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Vanderbilt University Medical Center
Social Communication Disorder, Autism
Feasibility Trial of Parent-delivered Social Communication Program
The Hanen Centre®'s More Than Words® (MTW) program is a globally used, parent coaching intervention delivered by speech-language pathologists (SLPs) to parents of children with social communication challenges, including those who…
- Trial name
- NCT06847347
- Testing
- More Than Words®
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- Western University, Canada
Language Disorder
Efficacy of AMALS in Treating Language Impairment in Children
The goal of this proposal is to examine the efficacy of a manualized treatment intervention, AMALS: Addressing Multiple Aspects of Language Simultaneously, which is designed to remediate semantic, morphological, and syntactic…
- Trial name
- AMALS (NCT00840060)
- Testing
- AMALS, DTA
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Lamar University
Dystonia, Primary, Dysarthria
Study of Speech Disorders , Voice and Swallowing in Primary Dystonia Oromandibular
To better define the clinical characteristics of oromandibular dystonia, we aimed to study voice, speech and swallowing disorders in idiopathic oromandibular We planned to include consecutive patients followed in Lille Movement…
- Conditions
- Dystonia, Primary, Dysarthria, Dysphonia, Dysphagia
- Trial name
- DOM (NCT03380676)
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Hearing Loss
Maximizing Language Development in Children With Hearing Loss
The purpose of this study is to evaluate the effects of early intervention on language skills for children with hearing loss.
- Trial name
- NCT01963468
- Testing
- Early language intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Cerebral Palsy
Translation of the Cerebral Palsy Quality of Life Questionnaire in Local Languages of Pakistan.
Descriptive analytical study to translate the CP-QOL into local languages of Pakistan that are, Pashto, Urdu, Punjabi, Sindhi and Balochi languages.
- Trial name
- NCT04852159
- Where
- Pakistan
- Volunteers
- 525 people
- Sponsor
- Riphah International University
Autism Spectrum Disorders, Non-verbal Learning Disorder
Comparison of ABLLS-R and Portage Guide in the Development of Receptive Language Skills Autism Spectrum Disorder.
Language is the system someone uses to communicate with another person. This covers the origins and construction of words, their definitions, and the use of language in various contexts.
- Trial name
- NCT06292520
- Testing
- Portage Guide Protocol, ABLLS-R protocol
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Dyslexia, Developmental
Developmental Dyslexia and Remediation Methods
At least, three theoretical frameworks are currently involved in therapeutic research in developmental dyslexia. Each theoretical framework relies on the type of underlying cognitive processes that is viewed as impaired: 1°)…
- Trial name
- DDMR (NCT04028310)
- Testing
- Phonological, Visual-attention
- Where
- France
- Volunteers
- 145 people
- Sponsor
- Fondation Lenval
Developmental Dyslexia
Comparing the Efficacy of tDCS and tRNS to Improve Reading Skills in Children and Adolescents With Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial random noise stimulation…
- Trial name
- NCT05832060
- Testing
- Active tDCS, Active tRNS
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Autistic Disorder of Childhood Onset With Full Syndrome
Impact of Sports Activity on Pragmatic Skills of Children
To investigate the effects of structured physical exercises/outdoor sports on social interaction/communication skills of children with Autism in Pakistan.
- Trial name
- NCT04593576
- Testing
- Physical activity protocol/out door sports, Intensive table teaching speech therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS)
Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Global Developmental Delay
This study explores a safe and effective new approach to improve language function in children with Global Developmental Delay (GDD).
- Conditions
- Developmental Delay Disorder, Repetitive Transcranial Magnetic Stimulation (rTMS), Global Developmental Delay, Language Disorders in Children
- Trial name
- NCT07369960
- Testing
- Transcranial magnetic stimulation, individualized language training
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiangya Hospital of Central South University
Down Syndrome, Cerebral Palsy
Measuring Aided Language Development
The focus of the current study is to systematically investigate the psychometric properties of a range of aided language measures, which are based on the Graphic Symbol Utterance and Sentence Development Framework (Binger \&…
- Conditions
- Down Syndrome, Cerebral Palsy, Apraxia of Speech, Speech Sound Disorder
- Trial name
- MALD (NCT06512168)
- Testing
- AAC Generative Language Intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Central Florida
Pulpal and Periapical Diseases
Diagnostic Accuracy of Educated Large Language Models in Endodontic Diagnosis and Case Difficulty Assessment
This diagnostic test accuracy (DTA) study aims to evaluate the diagnostic performance of educated large language models (Educated ChatGPT (GPT-5.5 Pro), Educated Gemini 3.1 Pro, and Educated Claude Opus 4.7) in endodontic…
- Trial name
- NCT07706894
- Testing
- ChatGPT, Gemini, Calude
- Volunteers
- 349 people
- Sponsor
- Cairo University
Developmental Language Disorder
Training Caregivers to Teach Vocabulary to Children With Language Impairment
The purpose of this study is to determine whether Spanish-speaking caregivers can learn to teach science vocabulary to their children with the use and educational app and a short training video with target words.
- Trial name
- DLD (NCT07519629)
- Testing
- Robust vocabulary intervention
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Northern Arizona University
Autism Spectrum Disorder
Peer Interventions for Preschoolers With Autism
This proposal will evaluate a series of peer-mediated interventions (PMIs) for preschool children (3 to 6 years) with ASD and limited or no spoken language, using an innovative Sequential Multiple Assignment Randomized Trial…
- Trial name
- PIPA (NCT05799599)
- Testing
- Stay-Play-Talk Basic, Stay-Play-Talk Plus, Stay-Play-Talk Advanced
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of Kansas
Epilepsy
Pediatric Language and Memory Mapping in Refractory Epilepsy Using Magnetoencephalography
This is a pilot research study where language and working memory tasks will be used to study brain activities from children with epilepsy.
- Trial name
- NCT04888637
- Testing
- Baseline MEG Test, Receptive Language Task, Memory Task
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Arkansas
Dyslexia, Learning Disorders
Comprehensive Program to Improve Reading and Writing Skills in At-Risk and Dyslexic Children
This project is evaluating programs to improve reading and writing skills in children who have or are at risk for having reading disabilities.
- Trial name
- NCT00061412
- Testing
- Comprehensive program to improve reading and writing skills
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Language Disorders in Children, Learning; Developmental Disorder
Impact of Teacher Training and the Introduction of Early Adjustments on the Developmental Trajectory of Children at Risk of SLLD in Pre-school.
The high incidence of neurodevelopmental disorders, including specific language and learning disorders, and their profund impact on the schooling of the children concerned remains a major public health concern.
- Trial name
- PRISME-TSLA (NCT06062147)
- Testing
- Teacher training
- Where
- Reunion
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
Autism, Autism Spectrum Disorder
Randomized Controlled Trial of the P.L.A.Y. (Play and Language for Autistic Youngsters) Project Intervention for Autism
This study is a large, multi-site, randomized controlled NIH trial that evaluates whether The P.L.A.Y. (Play and Language for Autistic Youngsters) Project is effective.
- Trial name
- PLAY (NCT01768806)
- Testing
- PLAY Project Intervention for Autism, Special education pre-school
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Richard Solomon MD, Plc
Stuttering, Stuttering, Childhood
Speech Processing in Stuttering
This research is being done to better understand stuttering, specifically how people who stutter may process and/or produce speech.
- Conditions
- Stuttering, Stuttering, Childhood, Stuttering, Adult
- Trial name
- NCT04929184
- Testing
- Speech and non-speech tasks
- Where
- 2 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- University of Michigan