Clinical trials: Late Effects
Childhood Cancer, Genetic Predisposition
Genetic Risks for Childhood Cancer Complications in Switzerland
The objectives of the GECCOS project are to identify genetic variants associated with complications of childhood cancer using genotype-phenotype association studies.
- Conditions
- Childhood Cancer, Genetic Predisposition, Late Effect
- Trial name
- GECCOS (NCT04702321)
- Testing
- Procedure: Biospecimen Collection, Procedure: Medical Chart Review
- Where
- Switzerland
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Geneva
Sequelae of; Infection, Post Infection Glomerulonephritis
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period.
- Conditions
- Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder)
- Trial name
- sequelae (NCT04846010)
- Testing
- PurWet, FurFat, PurApo
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- All Natural Medicine Clinic, LLC
Cerebral Palsy Hypoxic-Ischemic Encephalopathy Intracranial Hemorrhage
Autologous Bone Marrow Mononuclear Cell Transplantation Combined With Rehabilitation in Children With Sequelae of Hypoxic-Ischemic Encephalopathy or Intracranial Hemorrhage
This study evaluates the safety and preliminary efficacy of autologous bone marrow mononuclear cell transplantation combined with rehabilitation in children with neurological sequelae caused by hypoxic-ischemic brain injury or…
- Trial name
- BMMCT-CP (NCT07527104)
- Testing
- Autologous Bone Marrow Mononuclear Cell Transplantation
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- National Children's Hospital, Vietnam
Sarcoma
Late Effects of Treatment for Sarcomas in Children
This study will examine late effects of treatment for sarcoma (bone and soft tissue cancers) in children. Survival of patients with these diseases has improved over the years, but long-term adverse effects of treatment have also…
- Trial name
- NCT00006515
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- National Cancer Institute (NCI)
Suicide, Fatal Suicide
Case Control Psychological Autopsy of Suicide
Suicide is a leading cause of death worldwide, and identifying risk factors has been considered as the key initiative of suicide prevention.
- Conditions
- Suicide, Fatal Suicide, Non Fatal Suicidal Behavior
- Trial name
- NCT05097690
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tamkeen Saleem
Acute Lymphoblastic Leukemia/Lymphoma, Myelodysplasia
Natural History and Biology of Long-Term Late Effects Following Hematopoietic Cell Transplant for Childhood Hematologic Malignancies
This is a prospective non-therapeutic study, assessing the long-term toxicity of pediatric HCT for hematologic malignancies. This study is a collaboration between the Pediatric Blood and Marrow Transplant Consortium (PBMTC), the…
- Conditions
- Acute Lymphoblastic Leukemia/Lymphoma, Myelodysplasia, Acute Myelogenous Leukemia, Juvenile Myelomonocytic Leukemia
- Trial name
- NCT02338479
- Where
- 32 sites in United States
- Volunteers
- 340 people
- Sponsor
- Center for International Blood and Marrow Transplant Research
Surgical Site Infection (SSI)
Effect of Early vs Late Water Exposure After Cutaneous Surgery
This randomized controlled trial aims to compare the effect of early versus delayed water exposure after cutaneous surgeries on the incidence of surgical site infections.
- Trial name
- NCT07580274
- Testing
- Care as usual
- Volunteers
- 82 people
- Sponsor
- Pak Emirates Military Hospital
Brain Tumor, Acute Lymphoblastic Leukemia
Computerized Intervention for Amelioration of Cognitive Late Effects Among Childhood Cancer Survivors
Children treated for a brain tumor (BT) or acute lymphoblastic leukemia (ALL) show elevated rates of working memory impairment. Working memory (WM) is the ability to hold and manipulate information online; for example, when an…
- Trial name
- NCT01217996
- Testing
- Computerized working memory training program (intervention), Computerized working memory training program (control)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- St. Jude Children's Research Hospital
Moderate to Severe Traumatic Brain Injury
Ante-hypophyseal Dysfunctions in Children Following Moderate to Severe Traumatic Brain Injuries
Annual incidence of severe traumatic brain injuries (TBI) varies from 180 to 300 out of 100.000. Mortality or severe sequelae risk is increased 8 fold after a TBI.
- Trial name
- Endoc-TC (NCT01250132)
- Testing
- Biological and behavioral explorations
- Where
- 2 sites in France
- Volunteers
- 110 people
- Sponsor
- Hospices Civils de Lyon
Impacted Third Molar Tooth
Topical Arnica and Mucopolysaccharide Polysulfate on Postoperative Pain, Edema and Trismus
The present study was to evaluate the effect of topical Arnica and MPSP application with respect to visual analogue scale (VAS) scores, maximal interincisal opening (MIO) and edema values after mandibular impacted third molar…
- Trial name
- NCT04534426
- Testing
- : Arnica montana, Mucopolysaccharide polysulfate, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Human Papillomavirus
Immunogenicity of Gardasil and Twinrix and the Effect of a Dose of Gardasil or Cervarix Given 42 Months Later.
Two human papillomavirus vaccines are now commercially available. No clinical data exist regarding: The immunogenicity and safety of Gardasil and Twinrix when co-administered.
- Trial name
- NCT01456715
- Testing
- Gardasil vaccine, Immunogenicity, Booster dose., Cervarix Vaccine, Immunogenicity, Booster Dose.
- Where
- Canada
- Volunteers
- 418 people, healthy volunteers welcome
- Sponsor
- Laval University
Lung Diseases, Bronchopulmonary Dysplasia
Late Sequelae of Bronchopulmonary Dysplasia
To measure the cardiopulmonary function in individuals who developed bronchopulmonary dysplasia (BPD) at Stanford University Medical Center from 1964-1973 and to determine the factors associated with the presence of…
- Trial name
- NCT00005287
- Sponsor
- Stanford University
Computer Vision Syndrome
Prevalence and Sequelae of Computer Vision Syndrome in Egyptian Universities
CVS-F4 questionnaire will be used as an instrument to survey CVS prevalence and severity among medical students
- Trial name
- NCT05187221
- Testing
- CVS Group
- Where
- 2 sites in Egypt
- Volunteers
- 8,085 people, healthy volunteers welcome
- Sponsor
- Sohag University
Neonatal Care Neonatal Comfort Swaddled Bathing Wipe Bathing
The Effect of Wiping and Swaddling Bath Methods Applied in the Neonatal Intensive Care Unit on Neonatal Comfort: a Randomized Controlled Trial
This study will be conducted as a randomized controlled trial to examine the effects of different bathing methods on neonatal comfort.
- Trial name
- WS-Bath RCT (NCT06887686)
- Testing
- Swaddled Bath Intervention Wipe Bath Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Gamze Gocmen
Hematocrit Anemia, Acidosis
Placental Transfusion in the 'Natural' Delivery: Effect of Early and Late Umbilical Cord Clamping
The investigators conducted a randomized controlled trial (parallel group study with 1:1 randomisation) comparing early cord clamping (ECC, at 60 seconds) and delayed cord clamping (DCC, at 180 seconds) in 90 cases of 'normal'…
- Trial name
- NCT04459442
- Testing
- Umbilical cord clamping at birth.
- Where
- 3 sites in Italy
- Volunteers
- 90 people
- Sponsor
- Policlinico Abano Terme
Carbon Monoxide Poisoning
Neurological Sequelae in Patients With Acute Carbon Monoxide Poisoning
The purpose of this study is to access the clinical characteristics and risk factors for neurological sequelae after acute carbon monoxide poisoning.
- Trial name
- NCT04925297
- Testing
- No intervention
- Where
- China
- Volunteers
- 1,250 people
- Sponsor
- The First Hospital of Jilin University
Shaken Baby Syndrome
Predictors of Sequelae Appearance in Shaken Baby Syndrome
This is an observational, prognostic and prospective study. It is about the Prognostic Factors for sequelae in children with a history of Shaken Baby Syndrome (SBS) in the Central region in France.
- Trial name
- FPASSBS (NCT04105673)
- Testing
- Clinical examination and survey
- Sponsor
- University Hospital, Tours
Postoperative Pain
Intraoperative Local Anaesthetic and Postoperative Pain
Background: Intraoperative wound infiltration with local anaesthetic is commonly used. Apart from the obvious immediate action it has been supported that a possible down regulation of pain receptors may lead to longer effects.
- Trial name
- Pain-1 (NCT02171299)
- Testing
- Wound infiltration with local anaesthetic, Ropivacaine
- Where
- Greece
- Volunteers
- 400 people
- Sponsor
- Hellenic Red Cross Hospital
Respiratory Infection, COVID-19 Respiratory Infection
COVID-Like Illness Respiratory Pathogens. A Prospective Cohort on the COVID-19 Post-acute Condition
Identifying multiorgan sequalae and complications through high quality, prospective matched controlled studies throughout the course of COVID-19 is important for the acute and long-term management of patients and for health…
- Conditions
- Respiratory Infection, COVID-19 Respiratory Infection, Sequelae of; Infection
- Trial name
- CLEAR (NCT05047666)
- Volunteers
- 1,232 people
- Sponsor
- Bernhard Nocht Institute for Tropical Medicine
Covid19
Collection of SARS CoV-2 (COVID-19) Virus Secretions and Serum for Countermeasure Development
Collection of SARS-COV-2 Secretions and Serum for Countermeasure Development (aka ClinSeqSer) is an observational study to understand natural history of SARS-COV-2 infections among special populations and characterise post-covid…
- Trial name
- NCT04956445
- Where
- 2 sites in United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Tulane University