Clinical trials: Lean
Type 1 Diabetes, Obesity
The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action
Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for complications.
- Trial name
- NCT05414409
- Testing
- Metformin
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Heba M. Ismail
Obesity, Glucose Intolerance
Prevalence of Carbohydrate Intolerance in Lean and Obese Children
The prevalence of obesity in children is reaching epidemic proportions. Excess adiposity is more than just a cosmetic problem, having substantial metabolic consequences.
- Conditions
- Obesity, Glucose Intolerance, Diabetes, Acanthosis Nigricans
- Trial name
- NCT00000112
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Center for Research Resources (NCRR)
Prematurity; Extreme, Feeding Disorder Neonatal
Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk
The central hypothesis of this clinical trial is that, in extremely preterm infants, protein-enriched human milk diets compared to usual human milk diets during the first 2 weeks after birth increase fat-free mass (FFM)-for-age Z…
- Conditions
- Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure
- Trial name
- NCT04325308
- Testing
- Protein-enriched human milk diet, Usual human milk diet
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Alabama at Birmingham
Type 2 Diabetes
The Role of Amylin and Incretins on Postprandial Metabolisms in Adolescents With Type 2 Diabetes Mellitus (T2DM).
To study postprandial metabolism in lean, obese and T2DM adolescents using a mixed meal challenge. Specifically we will be measuring the following parameters of postprandial metabolism: 1.
- Trial name
- NCT00361946
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Dietary Proteins, Indicator Amino Acid Oxidation
The Effect of Dairy and Dairy-Free Alternative Beverages on Post-Exercise Anabolism in Active Youth
The growth and development of lean body mass (i.e., muscle and bone) is instrumental to health and performance across the lifespan, especially in youth, as they actively experience growth.
- Trial name
- PBS (NCT05827666)
- Testing
- 2% milk beverage, Almond milk alternative beverage, Soy milk alternative beverage
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Growth, Low Weight
Study to Evaluate the Effect of Short Treatment With Nutritional Supplementation Standardized Innovative Formula, on Growth and Weight Gain in Short and Lean Prepubertal Children
Study design: Double blind, randomized, placebo controlled study.The proposed study will consist of two main segments: 1. Segment 1 is aimed to assess the effect of 6-12 months treatment with nutritional supplementation…
- Conditions
- Growth, Low Weight, Low Height
- Trial name
- Formula (NCT01158352)
- Testing
- Nutritional supplementation formula
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Obesity
Tissue Composition of Newborn Infants of Obese and Lean Mothers
0-hypothesis: the tissue composition of newborn infants is not modified by lifestyle intervention during pregnancy
- Trial name
- NCT01235676
- Testing
- diet, Exercise
- Where
- Denmark
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Obesity
Longitudinal Assessment of Cardiovascular and Metabolic Parameters in Obese and Lean Children
The investigators hypothesize that cardiovascular and metabolic alterations due to obesity already manifest at childhood age. To identify these alterations and risk factors, the investigators have established a cohort of 177…
- Trial name
- NCT01605123
- Where
- 2 sites in Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Type 1 Diabetes
Sleep and Type 1 Diabetes
The primary goal of the study is to determine whether insufficient sleep is associated with poor glycemic control in type 1 diabetic children.
- Trial name
- SLEEPT1D (NCT02494375)
- Testing
- Sleep and glucose assessments
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Hospices Civils de Lyon
Ulcerative Colitis
Effects of WB-EMS in Ulcerative Colitis Patients
The purpose of this study is to determine the effect of 12 weeks of WB-EMS either applicated passive in a supine resting position or active during slight movements compared with a non-training control group on body composition…
- Trial name
- NCT02144129
- Testing
- active Whole Body Electromyostimulation, Passive WB-EMS, WB-EMS application
- Where
- Germany
- Sponsor
- University of Erlangen-Nürnberg Medical School
Inflammatory Bowel Disease
Resistance Training Intervention to Promote Lean Mass in Youth With IBD
Evaluate feasibility, safety, and preliminary estimates of resistance training (RT) efficacy to promote lean body mass accrual in patients with CD aged 14-18.
- Trial name
- NCT04017637
- Testing
- Resistance Training
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Blood Pressure, Arrhythmia
Effects of Fatty and Lean Fish Intake on Cardiovascular Risk Factors in Subjects With Coronary Heart Disease
The aim of the study is to examine the effects of fatty fish and white (lean) fish on cardiovascular disease risk factor levels in subjects with established coronary heart disease using multiple medications.
- Conditions
- Blood Pressure, Arrhythmia, Inflammation
- Trial name
- NCT00720655
- Testing
- Dietary intervention
- Where
- Finland
- Volunteers
- 33 people
- Sponsor
- University of Eastern Finland
Pediatric Obesity
Body Composition Changes With Albuterol and Caffeine Versus Placebo in Adolescents
The purpose of this study is to determine whether taking a combination of caffeine and albuterol three times per day will increase muscle and decrease fat in your child's body and to determine how these medications make your…
- Trial name
- CAMP (NCT02740660)
- Testing
- Caffeine 100mg / Albuterol 4mg, Family weight management counseling
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Growth Disorders, Low Weight
Long Term Effects of Nutritional Supplementation on Final Height
The proposed study is an extension study to two ongoing double blind, randomized, placebo-controlled studies evaluating the effect of gender-specific nutritional supplementation on growth of short and lean adolescent boys and…
- Conditions
- Growth Disorders, Low Weight, Short Stature
- Trial name
- NCT03323177
- Testing
- Gender specific nutritional standardized formula, Follow-up only
- Where
- Israel
- Sponsor
- Rabin Medical Center
Undernutrition
The Comparison of Handgrip Strength, Lean Mass, and Blood Pressure in Primary School Children Aged 8-10 Years Old With Undernutrition and Normal Nutritional Status
Undernutrition occurs in 900 million individuals globally, so it is a very important health problem because it contributes to high mortality rates, especially in children.
- Trial name
- NCT05952479
- Where
- Indonesia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitas Airlangga
Diet Modification
Increasing Lean Protein Intake in Preschool-age Children and Assessing Effects on Cognition and Select Health Outcomes
The proposed project addresses the goal of exploring preschooler's ability to recognize changes in feelings of hunger/satiety based on consuming a snack and a meal (lunch/dinner) that are either based on the usual childcare…
- Trial name
- NCT06882252
- Testing
- Low glycemic index diet
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sibylle Kranz, PhD, RDN
Insulin Resistance
The Influence of Breakfast on Hormone Responses and Cognitive Performance
The purpose of this study is to see what effect skipping breakfast versus consuming breakfast has on cognitive performance and the hormones responsible for glucose homeostasis in lean and obese adolescent males.
- Trial name
- NCT03005951
- Testing
- A= Yes Breakfast, B=No Breakfast
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Growth Problem, Low Weight
Evaluating the Effect of Nutritional Supplementation on Growth of Short and Lean Adolescents Girls
Study design: Double blind, randomized, placebo controlled study. Participants will be randomly assigned either to the intervention group or the placebo control group.
- Trial name
- NCT02397200
- Testing
- Nutritional supplementation standardized formula
- Where
- 3 sites in Israel
- Volunteers
- 99 people
- Sponsor
- Rabin Medical Center
Obesity, Type 2 Diabetes
Prevalence of Carbohydrate Intolerance in Lean and Overweight/Obese Children
The purpose of this study is to determine the prevalence of impaired glucose (carbohydrate) tolerance in lean children with a family history of diabetes and in overweight/obese children with or without a family history of…
- Trial name
- NCT01967849
- Testing
- Oral Glucose tolerance test
- Where
- United States
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Yale University
Healthy
The Effect of Dairy on Bone Mass and Body Composition in 4th-8th Grade Boys and Girls
Building stronger bones during pubertal growth could reduce lifelong fracture risk. This project is an 18 month dairy intervention study for overweight and healthy weight 4th-8th grade boys and girls.
- Trial name
- B3 (NCT00635583)
- Testing
- Increased Dairy Consumption
- Where
- 2 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Purdue University