Clinical trials: Learning Disorder
Cerebral Palsy
Locomotor Learning in Infants at High Risk for Cerebral Palsy
The objective of this project is to characterize the evolution of locomotor learning over the first 18 months of life in infants at high risk for cerebral palsy (CP).
- Trial name
- NCT04561232
- Testing
- Prone and Upright Locomotor Training
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Children's Hospital of Philadelphia
Colorectal Cancer Metastatic, Colorectal Cancer Stage III
COLONYVAQ™, a Quantum-Classical Guided Personalized Neoantigen Vaccine for MSS Stage III Colorectal Cancer
This is an early phase I, single-arm, open-label clinical study designed to evaluate the safety, tolerability, and feasibility of COLONYVAQ-CRC, a physics-aware, quantum-classical AI-guided personalized neoantigen peptide…
- Conditions
- Colorectal Cancer Metastatic, Colorectal Cancer Stage III, Colorectal Cancer Stage IV
- Trial name
- COLONYVAQ™-CRC (NCT07328087)
- Testing
- Experimental: COLONYVAQ-CRC + mFOLFOX6 or CAPOX + Nivolumab
- Where
- Greece
- Volunteers
- 12 people
- Sponsor
- Biogenea Pharmaceuticals Ltd.
Growth Disorders, Malnutrition
Evaluation of NICHE Programme Activities in Kenya
This study evaluates the impact of additional cash and nutritional counselling on nutrition outcomes in pregnant women and children up to the age of two years in CT-OVC (cash transfer- orphan and vulnerable children) households…
- Trial name
- NCT03518593
- Testing
- Cash and counselling
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Kimetrica LLC
Agraphia
Visual Perceptual Motor Training on Kindergarteners
The study aims to investigate the effects of different visuomotor training programs on children's visuomotor skills and handwriting performance.
- Trial name
- NCT05795738
- Testing
- Chinese character-based visuomotor training program, traditional visuomotor training program
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Cerebral Palsy
Bike Skills Training for Children With Cerebral Palsy
An assessor blinded multi-centre randomized controlled trial will be conducted in which 60 participants will be randomized to either a novel task-specific approach to training bike skills or a parent-led home program comparison…
- Trial name
- CPBIKERCT (NCT03003026)
- Testing
- Novel task-specific bike skills training program, Parent-led home-based bike skills training program
- Where
- 2 sites in Australia
- Volunteers
- 62 people
- Sponsor
- Murdoch Childrens Research Institute
COVID-19 Pandemic
Animation Supported COVID-19 Education
Introduction: The COVID-19 epidemic and related mutations, which affect the whole world, continue to increase globally. In particular, this crisis adversely affects school-age children's quality of life.
- Trial name
- COVID-19 (NCT05633485)
- Testing
- Animation-Supported Education
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Siirt University
Complementary Feeding, Pediatric Nurse
The Effect of Technology-Based Education Given to Mothers During the Transition to Complementary Feeding on Infant Development, Transition to Complementary Feeding Behavior, and Mothers' Anxiety Levels
This study will be conducted as a randomized controlled pre-test post-test study to determine the effects of technology-based complementary feeding training given to mothers during the transition period of babies to complementary…
- Trial name
- NCT07487493
- Testing
- Transition to traditional complementary feeding
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Anxiety, Depression
Research of Prevention and Intervention of Mental Health Problems
The purpose of this research is to establish a suitable community-based model for Chinese culture,to improve the community recognition of common mental disorders,as well as its treatment and control.
- Conditions
- Anxiety, Depression, Alcohol-abuse
- Trial name
- RPIMHP (NCT01422447)
- Testing
- regular intervention, community intervention
- Where
- 7 sites in China
- Volunteers
- 42,016 people
- Sponsor
- Shanghai Mental Health Center
Tic Disorders
Clinical Efficacy and Change of Life Quality Through Using the Comprehensive Behavioral Intervention Treatment for Tics
Study on the clinical efficacy and change of life quality through using the Comprehensive Behavioral Intervention Treatment for Tics (CBIT)
- Trial name
- NCT04765085
- Testing
- comprehensive behavioral intervention therapy (CBIT), Aripiprazole 5Mg Oral Tablet
- Sponsor
- Children's Hospital of Fudan University
Congenital Heart Diseases
Transition From Adolescents to Adulthood for Patients With Congenital Heart Diseases
The Investigators aim to measure the impact of a transition program in congenital cardiology in terms of health-related quality of life.
- Trial name
- NCT03005626
- Testing
- Therapeutic education, Standard follow-up
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Montpellier
Inflammatory Bowel Diseases, Crohn Disease
The Effect of MedicijnWijs on Adherence to Azathioprine Therapy in Adolescents With IBD
Medication non-adherence is an existing problem in patients with inflammatory bowel diseases (IBD). Adherence rates are especially low in children and adolescents.
- Conditions
- Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
- Trial name
- MEDICATION (NCT05321485)
- Testing
- MedicijnWijs
- Where
- 3 sites in Netherlands
- Volunteers
- 30 people
- Sponsor
- Maxima Medical Center
Breast Cancer, Magnetic Resonance Imaging
Artificial Intelligence Analysis for Magnetic Resonance Imaging in Screening Breast Cancer in High-risk Women
Use Convolutional Neural Networks Analysis for Classification of Contrast-enhancing Lesions at Multiparametric Breast MRI. Build an abbreviated protocal, and investigate whether an abbreviated protocol was suitable for breast…
- Trial name
- NCT04996615
- Testing
- no intervention
- Where
- 2 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Peking University People's Hospital
Virtual Reality, Epilepsy
Effect of VR-ESMEPP on Parents' Seizure Management
Objective: This study aims to evaluate the knowledge, skills, and motivation of parents regarding management of epileptic seizures, by developing a "Virtual Reality Based Seizure Management Education Program for Parents…
- Conditions
- Virtual Reality, Epilepsy, Seizure, Child
- Trial name
- VR-ESMEPP (NCT05500638)
- Testing
- Virtual Reality
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Intellectual Disability, Variable, Autism Spectrum Disorder (ASD)
School-Based Sensory Processing and Daily Living Skills-Focused Occupational Therapy Program
This study aims to develop and evaluate a school-based occupational therapy program focused on sensory processing and activities of daily living for children with Autism Spectrum Disorder and Intellectual Disability.
- Trial name
- NCT07326267
- Testing
- Individual School-Based Occupational Therapy Sessions, Sensory Preparation Using Proprioceptive, Vestibular, and Tactile Input, Task-Oriented Activities of Daily Living Training
- Volunteers
- 40 people
- Sponsor
- Çankırı Karatekin University
Autism Spectrum Disorder, Neurodevelopmental Disorders
School-based Paraeducator Education for Engagement at Recess
The purpose of the proposed three-site study is to test whether an educator-level implementation strategy, coaching, with or without a school-level implementation strategy, school-based teams, will maximize paraeducators' use…
- Trial name
- SPEER (NCT06559267)
- Testing
- Remaking Recess, TEAM
- Where
- 3 sites in United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Washington
Abdominal Pain, Irritable Bowel Syndrome
Pain Processing and Pain Neuroscience Education in Children With Chronic Abdominal Pain
The primary scientific objective of the study entails examining whether altered endogenous pain inhibition is present in children with functional abdominal pain (FAP) and irritable bowel syndrome (IBS) compared with healthy…
- Trial name
- NCT02880332
- Testing
- Usual care, Pain Neuroscience education, Extra care
- Where
- Belgium
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Autistic Disorders Spectrum
Word Learning in Children With Autism
The project highlights one of the primary areas of research within the KIDDRC- language and communication. The focus is on language and communication in children with autism and minimal verbal skills (less than 20 spoken words).
- Trial name
- NCT03419611
- Testing
- Multi-Modal, Treatment as Usual, High Intensity Multi-Modal
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kansas
Urinary Tract Infections, Malnutrition
Effect of Hygiene and Menstrual Hygiene Interventions on Learning and Psychosocial Wellbeing in Madagascar
A previous study in schools in rural Madagascar found that a bundle of hygiene-focused interventions substantially improved girls' learning outcomes.
- Conditions
- Urinary Tract Infections, Malnutrition, Inflammation, Stress
- Trial name
- KILONGA2 (NCT07702916)
- Testing
- Peer leadership/sensitization + sanitary pads, School infrastructure
- Where
- Madagascar
- Volunteers
- 3,080 people, healthy volunteers welcome
- Sponsor
- University of California Santa Cruz
Attention Deficit Disorder
Effectiveness of a Therapeutic Education Program in Improving Quality of Life of Children With ADHD and Their Parents
Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterized by attention deficit, impulsivity and hyperactivity. It's one of the most frequently encoutered disorder in child psychiatry.
- Trial name
- NCT05133284
- Where
- France
- Volunteers
- 24 people
- Sponsor
- University Hospital, Montpellier
COVID-19, SARS-COV-2 Infection
A Study to Learn About BNT162b2 (LP.8.1)-Adapted Vaccine Against SARS-CoV-2 in Children 5 Through 11 Years of Age That Are Considered at Higher Risk of Severe COVID-19
The purpose of this study is to learn about the safety, tolerability, and immunogenicity of an updated vaccine against COVID-19, called BNT162b2 (2025/2026 formulation).
- Trial name
- NCT07222384
- Testing
- BNT162b2 (2025/2026 formulation)
- Where
- 29 sites in United States, Puerto Rico
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
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