Clinical trials: Left Side
Coarctation of Aorta, Aortic Stenosis
Cardiac Remodeling and Circulating Biomarkers in Pediatric Left Ventricular Pressure Loading Lesions
This study is designed to learn more about children who have blockage of the left side of their heart. The goal is to determine how much the heart muscle has thickened before surgery and how it changes in the months after…
- Conditions
- Coarctation of Aorta, Aortic Stenosis, Cardiac Hypertrophy
- Trial name
- LVOTO (NCT02545790)
- Testing
- Echocardiogram, Serology
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Colorado, Denver
Heterotaxy Syndrome, Congenital Heart Defects
Molecular Genetics of Heterotaxy and Related Congenital Heart Defects
The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder.
- Trial name
- NCT02432079
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Indiana University
Fetal Left Heart Hypoplasia
Trial of Maternal Oxygen for Fetal Left Heart Hypoplasia
The purpose of this study is to determine if maternal hyperoxygenation is an effective treatment for fetal left heart hypoplasia versus room air (placebo).
- Trial name
- P-RCT-MHO (NCT02965638)
- Testing
- Oxygen
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Shaine Morris
Left Ventricular Systolic Function
Predictors of Left Ventricular Systolic Function Recovery After Transcatheter Aortic Valve Replacement
Investigate the preprocedural predictors of left ventricular systolic function Recovery after TAVR
- Trial name
- NCT05069168
- Testing
- Echocardiography before and after TAVR
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Assiut University
Takotsubo Cardiomyopathy
Is There a Genetic Predisposition for Acute Stress-induced (Takotsubo) Cardiomyopathy
Acute stress-induced (takotsubo) cardiomyopathy or broken heart syndrome presents like a heart attack, classically is triggered by intense emotional or physical stress and can have serious health consequences.
- Trial name
- GENETIC (NCT04513054)
- Testing
- Blood collection for genetic analysis
- Where
- 2 sites in United Kingdom
- Volunteers
- 700 people
- Sponsor
- University of Aberdeen
Heart Failure
LV Dysfunction Following Pacemaker Placement
Several studies have confirmed the link between chronic RV apical pacing and the development of heart failure and LV systolic dysfunction in some patients 1,2.
- Trial name
- NCT03850808
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Oregon Health and Science University
Hypoplastic Left Heart Syndrome, Obstructive Sleep Apnea Syndrome
Sleep Disordered Breathing in Children With Single Ventricle Physiology
This is an exploratory study designed to evaluate the incidence of, and to quantify sleep disordered breathing following stage I Norwood reconstructive surgery. Sleep disordered breathing will be correlated with: 1.
- Conditions
- Hypoplastic Left Heart Syndrome, Obstructive Sleep Apnea Syndrome, Single Ventricle Physiology
- Trial name
- NCT00156455
- Where
- United States
- Sponsor
- University of Rochester
Cotamination on Face Shield
Position of EGD in Droplet Spreading
The association between position of upper gastrointestinal endoscopy (EGD) and saliva droplet spreading has never been studied. In the era of contagious viral spreading, this pilot study is aimed to assess adenosine triphosphate…
- Trial name
- NCT04329013
- Testing
- Left lateral Position during intervention, Prone Position during intervention
- Where
- Thailand
- Volunteers
- 106 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Congenital Heart Disease
Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart Syndrome
The purpose of this study is to determine whether children and adolescents 8-18 years of age with HLHS and related lesions who have undergone stage I palliation during infancy using an allograft patch demonstrate continued…
- Trial name
- NCT01135485
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Pennsylvania
Transient Left Ventricular Ballooning Syndrome
Insights in the Pathophysiology of Transient Left Ventricular Ballooning Syndrome (TLVBS)
Transient left ventricular ballooning syndrome (TLVBS) is a cardiac syndrome that is characterised by acute but transient left ventricular (LV) dysfunction.
- Trial name
- NCT01076946
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Gasthuisberg
Coronary Artery Disease
Hypertonic Solution in Off Pump Coronary Artery Bypass Graft Surgery
This is a comparison between Hypertonic versus isotonic solution in a double blind randomized trial for off pump Coronary Artery Bypass Graft (CABG) surgery targeting the left marginal branch.
- Trial name
- NCT01463917
- Testing
- Hypertonic solution, Isotonic
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital Pitangueiras
Ankle Injuries, Syndesmotic Injuries
Grappler Interference Screw Post-Market Collection of Patient Reported Outcome Measures
Ambispective, multi-surgeon, single site, consecutive case series to determine the safety, performance, and benefits of the Grappler(R) Interference Screw.
- Conditions
- Ankle Injuries, Syndesmotic Injuries, Ankle Inversion Sprain, Deltoid Ankle Sprain
- Trial name
- NCT05190874
- Testing
- Grappler Interference Screw System
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Paragon 28
Effect of Drug
Effect of Captopril on GLS in Duchenne Myodystrophy
To outline the intermediate term effect of prescribing Captopril as an add on therapy on Left ventricular functions as measured by Global longitudinal strain in patients with Duchenne myodystrophy (DMD)
- Trial name
- NCT06485661
- Testing
- Captopril Tablets
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Ischemic Heart Disease
Correlation Between Left Ventricular Global Strain Measured by Speckle Tracking Echocardiography and Scar Burden Measured by Cardiac Magnetic Resonance Imaging in Patients With Ischemic Heart Disease
To verify whether GLS and LV mechanical dispersion, measured by two-dimensional speckle-tracking echocardiography (2D-STE) correlate with LV scar burden measured by cardiac MRI in patients with ischemic heart disease.
- Trial name
- NCT04970017
- Testing
- Cardiac MRI, Echocardiography
- Where
- Egypt
- Volunteers
- 51 people
- Sponsor
- Assiut University
Right Heart Failure
Accelerated LBBP for Patients With RHF and Severe TR
This study is a prospective, single-arm, target value clinical trial. We plan to prospectively enroll and follow 24 patients across three centers nationwide who have a low baseline heart rate (HR ≤ 60 bpm), meet the indication…
- Trial name
- ARCP (NCT07470047)
- Testing
- permanent pacemaker implantation
- Where
- 3 sites in China
- Volunteers
- 24 people
- Sponsor
- Shanghai Zhongshan Hospital
Atrial Fibrillation, Stroke
Left-Atrium-Appendage Occluder Register - GErmany
Evaluation of safety and effectiveness of implantable LAA occluder in clinical practice Indication: For which reasons is the indication for implantation of LAA-Occluder put for patients with atrial fibrillation? Safety: How save…
- Trial name
- LAARGE (NCT02230748)
- Where
- 4 sites in Germany
- Volunteers
- 643 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Hypertrophic Obstructive Cardiomyopathy
Transapical Beating-heart Septal Myectomy in Patient With Hypertrophic Obstructive Cardiomyopathy
The primary purpose of this study is to evaluate the feasibility, the safety and the efficacy of the transapical beating-heart septal myectomy for the treatment of hypertrophic obstructive cardiomyopathy.
- Trial name
- NCT05332691
- Testing
- Transapical beating-heart septal myectomy
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xiang Wei
AV Block, Bundle-Branch Block
Outcomes and Safety of Various Conduction System Pacing Methods
The aim of this study is to evaluate safety and clinical outcomes after different pacing approaches of conduction system pacing in a prospective registry.
- Conditions
- AV Block, Bundle-Branch Block, Atrial Fibrillation Rapid
- Trial name
- NCT04749836
- Testing
- His bundle pacing implantation, Left bundle branch area pacing implantation, Bachmann bundle pacing
- Where
- Slovenia
- Volunteers
- 150 people
- Sponsor
- University Medical Centre Ljubljana
Hypoplastic Left Heart, Congenital Heart Disease
Cardiac Biomarkers in Patients With Single Ventricle Physiology
All neonates with congenital heart disease undergoing stage one palliation (Norwood procedure, Damus-Kaye-Stansel procedure) at Texas Children's Hospital will be regularly monitored for B-type natriuretic peptide (BNP) and…
- Conditions
- Hypoplastic Left Heart, Congenital Heart Disease, Cyanotic Congenital Heart Disease, Cardiac Disease
- Trial name
- NCT03678909
- Testing
- Norwood Palliation / DKS / Damus-Kaye-Stansel procedure
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Baylor College of Medicine
Tetrology of Fallot, Heart Ventricle
Understanding Dexmedetomidine in Neonates After Open Heart Surgery
The purpose of this study is to determine what happens to dexmedetomidine in the body after it has been given to a newborn after heart surgery.
- Conditions
- Tetrology of Fallot, Heart Ventricle, Hypoplastic Left Heart
- Trial name
- Dex (NCT00576381)
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Athena Zuppa