Clinical trials: Lesion
Iron Deficiency Anemia
Prevalence of Oral Manifestations of Iron Deficiency Anemia in a Sample of Egyptian Population
According to WHO Reportin 2002, iron deficiency anemia was considered to be the most important contributing factor to the global burden of anemia.
- Trial name
- NCT03365570
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion
The Effect of ICON Treatment on WPL With Patients After Fixed Orthodontic Appliances
The aim of this study is to determine the effect of ICON on White spot lesions compared to CPP-ACPF plus.
- Trial name
- NCT03391180
- Testing
- ICON Remineralization, CPP-ACPF
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
White Spot Lesion of Tooth
Effect of Self Assembling Peptide on White Spot Lesion
During re-mineralization of white spot lesion, Will biomimetic self-assembling peptides improve the re-mineralizating effect of the post orthodontic white spot lesion compared to fluoride-based delivery systems?
- Trial name
- regeneration (NCT03930927)
- Testing
- Self Assembling peptide, remineralizing agent
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Raneen Ahmed
Injury;Sports, Biomechanical Lesions
Detection of Neuromuscular Deficits in Uninjured Youth Basketball Players
Basketball is an impact, coordination-opposition sport with continuous contact among players and it is considered a sport of medium-high injury incidence.
- Conditions
- Injury;Sports, Biomechanical Lesions, Musculoskeletal Injury
- Trial name
- DPL (NCT04796753)
- Testing
- Basketball Injury Defense
- Where
- Spain
- Volunteers
- 575 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Pulp Necrosis, Periapical Lesion
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique.
- Conditions
- Pulp Necrosis, Periapical Lesion, Anterior Teeth
- Trial name
- NCT03717337
- Testing
- Single visit pulp regeneration, Two visit pulp regeneration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
White Spot Lesion
Preventive Therapy of White Spot Lesions Using Different Remineralizing Agents in Children From 3 to 12 Years Old
Compare by clinical observation, photographs and fluorescence the efficacy of sodium fluoride, silanofluoride and thiefenfluoride in treating white spots.
- Trial name
- NCT04705428
- Testing
- FLUORINE VARNISH
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Root Canal Infection
Clinical and Radiographic Evaluation of the Synergistic Effect of Nano Silver Particles and Calcium Hydroxide Versus Triple Antibiotic Paste as Antibacterial Agents for Lesion Sterilization and Tissue Repair (LSTR) in Necrotic Primary Molars
Could the clinical and radiographic success of Nano Silver Particles and Calcium Hydroxide be comparable to that of Triple Antibiotic Paste as antibacterial agents for Lesion Sterilization and Tissue Repair (LSTR) in necrotic…
- Trial name
- NCT05681221
- Testing
- Nano silver particles and calcium hydroxide, TAP
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Cairo University
Occlual Caries, Proximal Caries
Clinical Evaluation of Self-Adhesive Bulk-Fil Hybrid Composite in Primary Molars
This study will evaluate the clinical performance of self-adhesive bulk-fill composite resin in the restoration of occlusal and occluso-proximal lesions in primary molars with hypothesis that there is no difference in the…
- Trial name
- NCT06724939
- Testing
- self-adhesive bulk-fill resin composite
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endoscopy in Intraventricular Lesions
Endoscopic and Endoscopic-Assisted Microsurgery of Intraventricular Lesions
Assess the efficacy of the endoscope as a single tool or as an adjuvant tool to the microscope in intraventricular procedures. Evaluate the limitations of the endoscope in these procedures.
- Trial name
- NCT04569201
- Testing
- Endoscope
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Assiut University
Aphthous Stomatitis
Safety, Galenic Acceptability and Efficacy of GV-328 Lozenges in Children With Oral Aphthosis
The aim of the study was to assess the safety, acceptability, and efficacy of product GV-328 for the treatment of childhood oral aphthous lesion.
- Trial name
- NCT04677062
- Testing
- GV-328
- Where
- Spain
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Skin Cancer
Multi-Center Study to Evaluate the Performance of DermDx for Primary Care Physicians in the Detection of Skin Cancers
The proposed study is a pivotal, multi-center retrospective reader study designed to determine whether the use of DermDx as a concurrent reading aid improves the performance of primary care physicians (PCPs) in diagnosing skin…
- Trial name
- NCT06463860
- Testing
- DermDx
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- MetaOptima Technology Inc.
Cervical Cancers, Vulvar Cancer
A Study of V503 (A Multivalent Human Papillomavirus [HPV] L1 Virus-Like Particle [VLP] Vaccine) in Preadolescents and Adolescents (V503-002)
This study will evaluate the immunogenicity and tolerability of V503 (a multivalent human papillomavirus [HPV] L1 virus-like particle [VLP] vaccine) in preadolescent and adolescent participants between 9 and 15 years old and…
- Conditions
- Cervical Cancers, Vulvar Cancer, Vaginal Cancer, Genital Lesions
- Trial name
- NCT00943722
- Testing
- V503
- Volunteers
- 3,074 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Adhesion
Dentin Treatments for Restorations of Cervical Lesions Non-Carious
The surface of non-carious cervical lesions (LCNC) is a challenge to adhesive systems, it presents a dentin layer sclera hypermineralized, presence of bacteria and lack of mechanical retention, so this study aimed to evaluate the…
- Trial name
- NCT02434601
- Testing
- Treatment of Dentin Surface, Dentin Surface, Treatment
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
White Spot Lesion of Tooth, Long Term Adverse Effects
Comparison of Efficacy Of Probiotic Toothpaste and Chlorhexidine Mouthwash To Reduce S.Mutans
Orthodontic appliance causes increase in plaque accumulation, especially around brackets, wires and attachments. Advances in orthodontics in recent time have led to improved quality of appliance and treatment procedures…
- Conditions
- White Spot Lesion of Tooth, Long Term Adverse Effects, Caries, Dental, Orthodontic Appliance Complication
- Trial name
- NCT03004196
- Testing
- Probiotic Toothpaste, Dr. Reddy's Clohex, Control Group
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peoples University, Bhanpur, Bhopal
Diagnoses Disease
Atypia of Undetermined Significance (AUS) / Follicular Lesion of Undetermined Significance (FLUS)
According to the guidelines for reporting thyroid fine needle aspirations known as The Bethesda System, the category of atypical cells known as AUS/ FLUS category has an estimated rate of 5 to 15% for malignancy.
- Trial name
- NCT03224754
- Testing
- Determination of risk of malignancy of these thyroid lesions
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Necrotic Pulp, Postoperative Pain
Evaluation of Postoperative Pain After Using 3MIX-TATIN Versus Calcium Hydroxide Iodoform Paste In Necrotic Primary Molars Treated by Lesion Sterilization and Tissue Repair Therapy
The aim of the current study is to compare a newly introduced material which is a combination of triple mix antibiotics paste and anti-hyperlipidemia drug simvastatin, the new material is named 3MIX-TATIN \& will be compared to…
- Trial name
- 3-mixtatin (NCT03084601)
- Testing
- Calcium Hydroxide, Iodoform, paste, 3-mixtatin
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahmoud M Saadoon
Child, Early Childhood Caries
Evaluation of Remineralizing Efficacy of Combination Varnishes on White Spot Lesions in ECC Children
The remineralizing efficacy of 3 fluoride varnishes were assessed in children with white spot lesion under 6 years of age ( children with early childhood caries)
- Trial name
- NCT03360266
- Testing
- Sodium Fluoride with CPP-ACP varnish, sodium fluoride with ACP varnish, 5% Sodium Fluoride Varnish
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Indira Gandhi Institute of Dental Science
Rhegmatogenous Retinal Detachment
Healaflow Patch for the Treatment of Rhegmatogenous Retinal Detachment
To report the surgical results of primary rhegmatogenous retinal detachment (RRD) repaired by 27G pars plana vitrectomy (PPV) combined with Healaflow patch and air tamponade, and do not need prone position postoperation.
- Trial name
- NCT03542162
- Testing
- Healaflow
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Premalignant Lesion, Oral Cancer
Diagnostic Accuracy of Mobile Phone Imaging Compared to Conventional Clinical Examination for Oral Cancer Screening
The aim of study is to evaluate the sensitivity and specificity of using mobile phone photographs versus conventional clinical examination as a screening tool for early detection of oral cancer.
- Trial name
- NCT06060288
- Testing
- Diagnosis by mobile phone imaging
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University
Benign Skin Tumor, Basal Cell Carcinoma
Study to Examine Lesions of the Skin Using Confocal Laser Microscopy
Using ex-vivo confocal laser scanning microscopy, a reliable statement can be made about the extent, histological structure and possible significance of a skin change without having to send tissue samples for demanding and…
- Conditions
- Benign Skin Tumor, Basal Cell Carcinoma, Melanoma, Squamous Cell Cancer
- Trial name
- NCT06598137
- Testing
- Ex vivo confocal laser microscopy
- Where
- Germany
- Volunteers
- 645 people, healthy volunteers welcome
- Sponsor
- LMU Klinikum