Clinical trials: Life Style Modification
Healthy Lifestyle, Health Behavior
Better App: (Further-)Development and Evaluation of a Digital Lifestyle Programme
In recent years, we developed and evaluated personalised lifestyle interventions, the BETTER programmes (BETER in Dutch, acronym for Move, Eat, Change).
- Trial name
- BETTERapp (NCT05837468)
- Testing
- BETTERapp
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Zuyd University of Applied Sciences
Obesity
Beverage Choice and Lifestyle Modification in Overweight Youth
The rise in childhood overweightness and concomitant increase in chronic disease risk warrants exploration into the effectiveness of interventions targeting the eating and activity habits of overweight youth.
- Trial name
- NCT01662570
- Testing
- Beverage Choice and Lifestyle Modification, Nutrition Education (NE)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Intellectual Disabilities (F70-F79), Down Syndrome (DS)
Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual Disabilities
IDHEApp will implement various educational technology tools and work with the families, teachers and caregivers to increase physical activity (PA) and improve healthy eating.
- Conditions
- Intellectual Disabilities (F70-F79), Down Syndrome (DS), Autism Disorder
- Trial name
- IDHEAPP (NCT07101523)
- Testing
- mHealth
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- University of Seville
Diabetes Mellitus, Type 2
Online Program Assisting Lifestyle Changes (Asterix 1.0 & Obelix 2.0)
The purpose of this study is to help Internet users to adopt and maintain a healthy lifestyle, it is imperative to increase self-management competencies to improve healthy eating and regular physical activity.
- Trial name
- OPAL (NCT00986375)
- Testing
- Intervention Group (IG), Active Control Group (ACG)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Freie Universität Berlin
Pregnancy, Gestational Diabetes
Targeted Lifestyle Change Group Prenatal Care
To conduct a randomized trial to determine the effect of Targeted Lifestyle Change Group Prenatal Care (TLC) on maternal and neonatal outcomes in women at high risk for developing gestational diabetes mellitus (GDM).
- Trial name
- TLC (NCT04090307)
- Testing
- TLC Group Prenatal Care
- Where
- 2 sites in United States
- Volunteers
- 305 people
- Sponsor
- University of North Carolina, Chapel Hill
Atherosclerosis, Cardiovascular Risk Factor
Early Vascular Ageing in the YOUth
This is a single-center observational study on adolescents to determine predictors of the early steps of the formation of atherosclerosis and to quantify their influence on Intima-Media-Thickness of the carotid artery and the…
- Conditions
- Atherosclerosis, Cardiovascular Risk Factor, Cardiovascular Diseases, Cardiovascular Pathology
- Trial name
- EVA4YOU (NCT04598685)
- Where
- Austria
- Volunteers
- 1,517 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Overweight, Obesity
Vikings Fitness Playbook: A Family Based Lifestyle Modification Program for Overweight and Obese Youth
Childhood cancer survivors (CCS) are prone to develop obesity and are at increased risk of developing cardiovascular disease and type 2 diabetes compared to the general pediatric population.
- Trial name
- NCT01442415
- Testing
- Lifestyle modification
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiovascular Risk Reduction
Young Hearts, Strong Starts
This is a cluster randomized trial of pediatric cardiovascular risk reduction guideline implementation in 32 clinical practices
- Trial name
- NCT01893593
- Testing
- Intervention, Control
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- RTI International
Obesity, Pediatric
Investigating the Efficacy of a Mobile App Intervention to Change Youth and Their Families' Health Behaviours
This study is the second of three sub-studies aimed at evaluating the outcomes of the Living Green and Healthy for Teens (LiGHT) program, delivered through the Aim2Be app (v2.2).
- Trial name
- NCT03651284
- Testing
- Aim2Be app with Live Coach + Fitbit + BMI tracking tools, Aim2Be app waitlist + Canadian Health Recommendations + Fitbit + BMI tracking tools, then flip to Aim2Be app with Virtual Coach + Fitbit + BMI tracking tools
- Where
- 6 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of British Columbia
Obesity
Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 Years
This study will be conducted to demonstrate weight loss efficacy by change in body mass index (BMI) and safety in adolescents age 12 to 17 years (inclusive) during 52 weeks of treatment with Belviq XR 20 milligrams (mg)…
- Trial name
- NCT03338296
- Testing
- lorcaserin hydrochloride XR
- Where
- 16 sites in United States
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Eisai Inc.
Transient Ischemic Attack, Non-disabling Stroke
Program of Rehabilitative Exercise and Education to Avert Vascular Events After Non-disabling Stroke or Transient Ischemic Attack: A Multi-site RCT
The objective of the Program of Rehabilitative Exercise and Education to avert Vascular Events after Non-disabling stroke and Transient ischemic attack (PREVENT) Trial is to determine whether the timely delivery of secondary…
- Trial name
- PREVENT (NCT00885456)
- Testing
- PREVENT program, Usual Care
- Where
- 2 sites in Canada
- Volunteers
- 187 people
- Sponsor
- Marilyn MacKay-Lyons
Osteoporosis
Improving Bone Health in Adolescent Girls: The Youth Osteoporosis and Understanding Total Health (YOUTH) Study
Osteoporosis affects nearly half of all American women over age 50. During the teenage years, girls can increase bone growth to decrease their risk of osteoporosis later in life.
- Trial name
- NCT00067600
- Testing
- Diet with increased fruits, vegetables, and calcium, Increased high impact activity and resistance training
- Where
- United States
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Life Style Modification, Childhood Obesity
Effects of Omega-3 Supplementation on Nutritional Status and Physical Activity of Obese Children
Omega-3 Long-Chain Polyunsaturated Fatty Acids has potential as a supplement that can accelerate the effects of a weight management program in children.
- Trial name
- NCT04156971
- Testing
- Omega 3, stage-based lifestyle modification intervention
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Cardiovascular Diseases, Cancer
Promoting Healthy Lifestyles Among Firefighters
Promoting Healthy Lifestyles: Alternative Models' Effects (PHLAME) is a research study to evaluate and compare two ways to promote healthy behaviors, (regular physical activity, less than 30% calories from fat, 5 or more servings…
- Conditions
- Cardiovascular Diseases, Cancer, Physical Activity, Nutrition
- Trial name
- PHLAME (NCT00006181)
- Testing
- Team-based intervention, One-on-one intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Food Habits
Texts For Healthy Teens: A Health Education Program for Adolescents
The overall objective is to examine if participating in an SMS-transmitted health educational program targeting a cluster of dietary factors over a period of weeks during the years of adolescence can induce durable changes…
- Trial name
- T4HT (NCT02809196)
- Testing
- 1: Tailored SMS program implicating friend and mother, 2: Standardized SMS program implicating friend and mother, 3: Tailored SMS program implicating friend, not mother
- Where
- Denmark
- Volunteers
- 7,890 people, healthy volunteers welcome
- Sponsor
- Centre for Fetal Programming, Denmark
Liver Fibrosis, Liver Steatosis
NAFLD and Liver Fibrosis in Obese Adolescents
Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disease resulting from excessive fat accumulation in the liver. Due to its close association with obesity, it has become the most common liver disease in children in the…
- Conditions
- Liver Fibrosis, Liver Steatosis, Weight Loss
- Trial name
- NAFLD (NCT04561804)
- Testing
- laparoscopic sleeve gastrectomy (LSG) and laparoscopic single anastomosis gastric bypass (LSAGB)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Health Behavior, Colorectal Neoplasms
Health Behavior Change in High-Risk Colorectal Cancer Individuals
Background Colorectal cancer is a significant health concern. For individuals identified as being at high risk for developing this disease, adopting healthy lifestyle behaviors is a powerful way to lower that risk.
- Conditions
- Health Behavior, Colorectal Neoplasms, Primary Prevention/Methods
- Trial name
- NCT07262840
- Testing
- Multi-component Health Promotion Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University, China
Non-Alcoholic Fatty Liver Disease
Lifestyle Guidance Methods in NAFLD
To determine the efficiency of lifestyle modification (due to a dietitian or digital application) compared to standard of care.
- Trial name
- INDIANA (NCT05792488)
- Testing
- Coach, App, Standard of care
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Ziekenhuis Oost-Limburg
Coronary Heart Disease
COR-PRIM: Problem-based Learning (PBL) After Coronary Heart Disease (CHD) - Long-term Evaluation in Primary Care of Self-care
The hypothesis is that problem based learning (PBL) in patient education positively affects self-care agency of lifestyle changes after an event of coronary heart disease (CHD).
- Trial name
- CORPRIM (NCT01462799)
- Testing
- PBL in patient education, Mailed patient information
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Linkoeping University
Coronary Heart Disease
Cardiovascular Rehabilitation - Effectiveness of the Tulppa Program
This study investigates the effectiveness of a Finnish Tulppa outpatient rehabilitation program. Tulppa is a group-based secondary prevention program for patients with vascular diseases.
- Trial name
- NCT03437616
- Testing
- Tulppa rehabilitation
- Where
- Finland
- Volunteers
- 300 people
- Sponsor
- Rehabilitation Foundation, Finland