Clinical trials: Limb Injury
Burn Injury, Postural Balance Disorders
Effects of Hop-Stabilization Training on Postural and Functional Rehabilitation in Children With Lower-Limb Burns
Children with severe burns affecting both lower limbs may experience persistent difficulties with balance, walking, and physical function.
- Conditions
- Burn Injury, Postural Balance Disorders, Gait Impairment
- Trial name
- NCT07896135
- Testing
- Progressive Hop-Stabilization Training, Traditional physical therapy
- Where
- Saudi Arabia
- Volunteers
- 54 people
- Sponsor
- Qassim University
Neurological Injury, Hemiplegia
Camp High 5: Evaluation of the Effect on Upper Limb Function
Randomized control trial to evaluate uni-manual and bimanual upper limb function as well as compare outcomes of varied cast wear in children with hemiplegic cerebral palsy (CP) following a hybrid camp model of modified constraint…
- Trial name
- NCT02875054
- Testing
- Constraint induced movement therapy (CIMT), Hand-arm bimanual intensive training (HABIT)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- NYU Langone Health
COVID, Corona Virus Infection
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study
This research aims to assess the use of an experimental and non-invasive procedure, Remote Ischemic Conditioning (RIC), as an adjunct therapy in attenuating severe COVID-19 disease.
- Conditions
- COVID, Corona Virus Infection, Acute Lung Injury, Ischemia Limb
- Trial name
- NCT04659460
- Testing
- Remote Ischemic Conditioning
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Trauma
Management of Extremity Injuries Registry
The primary objective of this study is to establish a data set that will be permissive of quality improvement studies/observations specific to life and limb salvage in comprisable extremity injuries.
- Trial name
- NCT07492758
- Testing
- Non-Interventional (Registry)
- Where
- United States
- Volunteers
- 999 people
- Sponsor
- Methodist Health System
Lower Limb Amputation Knee, Lower Limb Amputation Below Knee (Injury)
Validity and Reliability of The 3-Meter Backward Walk Test in Individuals With Lower Limb Amputation
Clinicians are routinely required to make decisions about fall risk among lower limb prosthesis users. For these decisions, clinicians should use valid, reliable, quantitative, and multidimensional measures of balance test for…
- Trial name
- NCT05095584
- Testing
- 3 meter backward walk test
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Tezel Yıldırım Şahan
Pain, Traumatic Limb Injury
Pain Reduction With Intranasal Medications for Extremity Injuries
This study compares the analgesic effect of intranasal sub-dissociative dosing of ketamine and intranasal fentanyl in children presenting to the Emergency Department with acute extremity injuries.
- Trial name
- PRIME (NCT02778880)
- Testing
- Ketamine, Fentanyl
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Osteosarcoma in Children, Radiation Toxicity
Phase I Clinical Trial of GRID Therapy in Pediatric Osteosarcoma of the Extremity
The primary objective of this study is to evaluate the toxicity profile of GRID therapy using dose levels of 10Gy, 15 Gy and 20Gy in pediatric osteosarcoma of the extremity.
- Trial name
- NCT03139318
- Testing
- GRID radiotherapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Arkansas
Spinal Cord Injury, Neuromodulation
Rehabilitation Combining Spatiotemporal Spinal Cord Stimulation and Real-time Triggering Exoskeleton After Spinal Cord Injury
Spinal cord injury (SCI) can be caused by trauma, inflammation, tumors, and other factors, often leading to issues such as impaired leg movement, abnormal sensation, and difficulties with bladder and bowel control.
- Conditions
- Spinal Cord Injury, Neuromodulation, Robot Assisted Gait Training
- Trial name
- SCS-EXS (NCT06881134)
- Testing
- SCS+EXS
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xuanwu Hospital, Beijing
Brain Injuries, Focal
VR Versus Task-Oriented Circuit Training on UL Sensorimotor in Children With Immature Brain Injury
To investigate and compare the effect of virtual reality and task-oriented circuit training on pinch grip and quality of life in children with with immature brain injury.
- Trial name
- NCT07827365
- Testing
- Virtual reality, Task-oriented circuit training
- Volunteers
- 44 people
- Sponsor
- October 6 University
ACL Injury
Neuromuscular Training Improves Single-Limb Stability
Pretest/post-test study design, study will try to determine if a 6-week neuromuscular training program designed to decrease the incidence of anterior cruciate ligament (ACL) injuries would improve single-limb stability in young…
- Trial name
- NCT04967937
- Testing
- Strengthening, resistance exercise, plyometric and dynamic movement training
- Where
- Pakistan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Upper Extremity Injury
Upper Extremity Force-velocity Profile in Swimmers
The aim of this study was to measure the changes in the upper extremity force-velocity profile of young swimmers at different training periods during a training season
- Trial name
- NCT05691673
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Leg Injuries, Ankle Injuries
Medico Economic Evaluation of Dermal Substitute Integra® for Coverage of Inferior Limb Traumatic Skin Loss
Comparison of 2 techniques of surgery on patients with inferior limb traumatic wounds: the innovative technique Integra® and the technique of reference: the flap surgery.
- Conditions
- Leg Injuries, Ankle Injuries, Foot Injuries
- Trial name
- INTEGRA® (NCT00906672)
- Testing
- INTEGRA®, Flap technique
- Where
- 7 sites in France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Bordeaux
Blister, Wound of Skin
Safety, Tolerability, and Pharmacokinetics of Ascending Topical Doses of TCP-25 Applied to Epidermal Suction Blister Wounds, Non-Healing Leg Ulcers and Patients With Dystrophic Epidermolysis Bullosa.
This is a three-part, Phase I, first-in-human study designed to evaluate the safety, tolerability, and potential systemic exposure of multiple topical doses of TCP-25.
- Conditions
- Blister, Wound of Skin, Epidermolysis Bullosa, Varicose Ulcer of Lower Limb
- Trial name
- NCT05378997
- Where
- Sweden
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Xinnate AB
Knee Injuries, Anterior Cruciate Ligament Injuries
Effect of Neuromuscular Warm-up on Injuries in Female Athletes
The goal of the study is to determine effect of coach-led neuromuscular warm-up on non-contact, lower extremity (LE) injury rates among female athletes in a predominantly non-white public high school system.
- Conditions
- Knee Injuries, Anterior Cruciate Ligament Injuries, Ankle Injuries, Lower Extremity Injuries
- Trial name
- NCT01092286
- Testing
- neuromuscular warm-up
- Where
- United States
- Volunteers
- 1,653 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Spinal Cord Injury Cervical, Spinal Cord Injury, Acute
Upper Limb Rehabilitation Using Non-invasive Spinal Cord Stimulation
The goal of this RCT study is to evaluate if combining activity-based therapy (ABT) with transcutaneous spinal cord stimulation (tSCS) can improve recovery of arm and hand movement in people with cervical spinal cord injury…
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injury, Acute, Spinal Cord Injury (Quadraplegia)
- Trial name
- CIME_upperlimb (NCT07361627)
- Testing
- Protocol 2: Combination of activity-based therapy and facilitatory transcutaneous spinal cord stimulation
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal
Deformity, Defect, Congenital
Observational Study on JuniOrtho Plating System for Deformities and Fractures Treatment in Lower Limb
Orthofix Srl put the JPS on the European market (2019) by the mean of a pre-market clinical evaluation made under the Medical Device Directive (MDD) requirements that were based on the analysis of the scientific literature of…
- Conditions
- Deformity, Defect, Congenital, Trauma
- Trial name
- JPS (NCT05245617)
- Testing
- JuniOrtho™ Plating System™
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Orthofix s.r.l.
Spinal Cord Injury
Functional Electrical Stimulation (FES) Cycling for Children With Spinal Cord Injuries (SCI)
The overall objective of this research project is to examine the clinical efficacy of lower extremity cycling with functional electrical stimulation to improve the health and fitness of children with spinal cord injuries (SCI).
- Trial name
- NCT00245726
- Testing
- FES Cycle, ES therapy, Passive (Motor Assist) Cycle
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Shriners Hospitals for Children
Peripheral Nerve Injury Upper Limb
Ultrasound Guided Placental Growth Factor Vs Platelet Rich Plasma Injection in Peripheral Nerve Injury: an Interventional Study
The goal of this clinical trial is to learn if placental growth factor injection and platelet rich plasma injection works to treat peripheral nerve injury in adults.
- Trial name
- NCT06638008
- Testing
- perineural injection
- Volunteers
- 75 people
- Sponsor
- Assiut University
Anterior Cruciate Ligament Injuries, Injuries, Knee
Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players
Background and justification: Women's football has a percentage of knee injury of 31.8%, and the anterior cruciate ligament lesion is between 2 and 4 times higher than the male.
- Conditions
- Anterior Cruciate Ligament Injuries, Injuries, Knee, Prevention & Control
- Trial name
- NCT04062578
- Testing
- Physiotherapy program of lumbopelvic stabilization and strengthening of the hip region musculature
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Upper Limb Wound, Lower Limb Wound
Wide-awake Local Anesthesia and no Tourniquet (WALANT) in Plastic Surgery
Wide-awake local anesthesia no tourniquet (WALANT) was proposed and performed in hand operations. Aim of this study is to present the use of WALANT in operations performed on the upper and lower limbs, evaluate its efficacy in…
- Conditions
- Upper Limb Wound, Lower Limb Wound, Anesthesia, Local
- Trial name
- NCT04992351
- Testing
- WALANT
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University Hospital, Ioannina