Clinical trials: Lip Deformity
Cleft Lip and Palate
Liposomal Bupivacaine Use in Alveolar Bone Graft Patients
The goal of this clinical trial is to learn if a pain medication called liposomal bupivacaine (brand name EXPAREL®) with epinephrine will provide better pain control, increased activity, and reduced use of opioids compared with…
- Trial name
- NCT06284434
- Testing
- Liposomal Bupivacaine, Bupivacain, Epinephrine
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kerry O'Rourke
Nose; Anomaly
Objective Assessment for Cleft Lip Nasal Deformity Correction
Rhinoplasty remains one of the most challenging procedures in plastic surgery, and patients with cleft lip nasal deformity pose an even greater challenge, in which biggest issue is to achieve caudal nose harmony and creation of…
- Trial name
- NCT03683199
- Testing
- Rhinoplasty
- Where
- Egypt
- Volunteers
- 1 people
- Sponsor
- Assiut University
Cleft Lip, Cleft Palate
Systematic Pediatric Care for Oral Clefts - South America
Cleft lip and palate are a significant component of morbid human birth defects in the developing world. This study measures the impact of having a child born with a cleft lip on subsequent maternal/infant family health, and…
- Conditions
- Cleft Lip, Cleft Palate, Congenital Defects
- Trial name
- NCT00097149
- Testing
- Systematic pediatric care
- Where
- Brazil
- Volunteers
- 696 people
- Sponsor
- NICHD Global Network for Women's and Children's Health
Cleft Lip and Palate, Maxillary Hypoplasia
Cleft Orthognathic Surgery Versus Distraction Osteogenesis - Which is Better?
Cleft lip and palate patients normally present with a sunken face due to collapse in the middle part of the face and inability of the upper and lower teeth to meet during chewing.
- Trial name
- NCT00930124
- Testing
- Orthognathic surgery, Distraction osteogenesis
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cleft Lip and Palate
Evaluation of the Effect of Prosthetic Management for Congenital Cleft Lip and Palate Infants on the Middle Ear Function
Aim of the study was to evaluate the effect of feeding appliance for congenital cleft lip and palate infants on the middle ear function
- Trial name
- NCT06075069
- Testing
- Feeding appliance
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Alexandria University
Cleft Lip and Palate
Test-Retest Reliability, Responsiveness and Interpretability of CLEFT-Q
The goal of this observational study is to test the questionnaire CLEFT-Q in a population of patients with cleft lip and/or palate. The main questions it aims to answer are: 1. Are CLEFT-Q scores reliable over time? 2.
- Trial name
- CLEFT-QSwePsyc (NCT05775679)
- Where
- Sweden
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Department of Plastic and Reconstructive Surgery
Sarcoma, Breast Cancer
Augmented Reality (AR): The Future of "Patient Information Leaflets
This project aims to assess a new type of Augmented Reality Patient Information leaflet, in order to demonstrate that it is a beneficial information resource to patients when facing the diagnosis of sarcoma, breast cancer or to…
- Conditions
- Sarcoma, Breast Cancer, Cleft Lip and Palate, Surgical Flap
- Trial name
- NCT04619030
- Testing
- Augmented Reality, Traditional leaflet
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- NHS Greater Glasgow and Clyde
Cleft Lip, Cleft Palate
Use of Titanium Plate in Rhinoplasty in Patients With Cleft Lip and Palate : Aesthetic and Functional Impact.
The patients in this study are all born with a cleft lip and palate. They underwent several interventions in childhood to take care of it.
- Trial name
- PETROL/TROPHIC (NCT03572907)
- Testing
- Rhinoplasty questionnaire
- Where
- France
- Sponsor
- Hospices Civils de Lyon
Blepharocheilodontic Syndrome
CDH1-associated Blepharocheilodontic Syndrome Registry
The aim of the CDH1-associated Blepharocheilodontic Syndrome (BCDS) registry is to better characterize the clinical features of this condition and exploring whether CDH1 variants linked to BCDS may also increase cancer risk.
- Trial name
- NCT07133464
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Cleft Lip, Cleft Palate
Effects of AlignBabyCleft (ABaCleft)
Since the appearance of presurgical infant orthopedic (PSIO) as a treatment for patients with cleft lip and palate ( CLP) , numerous techniques have been described with the aim of aligning the displaced alveolar segments and…
- Trial name
- (ABaCleft) (NCT05357092)
- Testing
- Appliance. Orthodontic appliance to carry out dentoalveolar movement
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid
Cleft Lip and Palate, Social Isolation
Perception of Appearance and Social Acceptance Between Cleft and Non-Cleft Children in Early Adolescence
Background: Using three-dimensional (3D) surface imaging, this study aims to understand the differences in perception between schoolchildren with and without cleft lip and palate (CLP), as well as to explore peer awareness and…
- Trial name
- Cleft social (NCT06539572)
- Testing
- Cleft lip repair; palatoplasty; alveolar bone grafting
- Where
- Taiwan
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Cleft Lip and Palate
Use of Computer Aided Design and 3D Printing for Anesthesiology Management in a Pediatric Patient With Cleft Facial Defect (3D Obturator) - Pilot Trial
Congenital malformations of the orofacial area are the most common congenital malformations in children with an incidence of 1.8 children with orofacial cleft per 1000 healthy births in the Czech Republic.
- Trial name
- Pilobtur (NCT04422964)
- Testing
- 3D Obturator
- Where
- Czechia
- Volunteers
- 40 people
- Sponsor
- Brno University Hospital
Palate, Cleft
Evaluation of Quality of Life After Orthognathic Surgery in a Cleft Lip and Palate Context
The purpose of this study is to compare, prospectively, the quality of life of patients with cleft lip and palate before and after orthognathic surgery.
- Trial name
- ORTHOQOL (NCT04049058)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Lille
Cleft Lip and Palate
Fabrication of Naso-alveolar Molding (NAM) Appliance in Cleft Lip and Palate (CLP) From Digital Magnetic Resonance Imaging (MRI) Face Scan
The purpose of this study is to fabricate a nasoalveolar molding (NAM) appliance that is digitally fabricated and 3 dimensionally printed utilizing an MRI face scan and to assess the fit of the NAM in new borns with cleft lip and…
- Trial name
- NCT04369638
- Testing
- 3D NAM, Traditional NAM
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- The University of Texas Health Science Center, Houston
Re-treatment of Cleft Lip and Nasal Deformation
Clinical Evaluation of Re-treatment of Cleft Lip and Nasal Deformation in Patients With Post Repair Deformities
Clinical Evaluation of Re-treatment of Cleft Lip and Nasal Deformation in Patients With Post Repair Deformities. A Randomized Controlled Study
- Trial name
- NCT07348185
- Testing
- Procedure / Surgery
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Neural Tube Defects (NTDs), Facial Cleft Defect
Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish Population
In a collaborative effort with the Health Research Board, the national organization for medical research in the Republic of Ireland, individuals with neural tube defects (NTDs) or facial cleft defects and their parents will be…
- Conditions
- Neural Tube Defects (NTDs), Facial Cleft Defect, Hereditary Oral Clefts
- Trial name
- NCT00341068
- Where
- United States
- Volunteers
- 7,451 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Cleft Lip and Palate, Bone Graft; Complications
Correlation Between Body Mass Index and Progressive Grafted Bone in Cleft Patients
The cleft patients received alveolar bone graft(ABG) for alveolar defect. Body mass index (BMI) was measured for each patients when receiving ABG.
- Trial name
- NCT05002920
- Testing
- alveolar bone grafting
- Where
- Taiwan
- Volunteers
- 39 people
- Sponsor
- Chang Gung Memorial Hospital
Cleft Palate, Cleft Lip
Targeting Surgeons' Decision-Making for Cleft Lip Surgery
Using separate prospective cohorts of patients who have lip revision and lip repair surgery, the objective of this clinical trial is to both qualitatively and quantitatively assess how surgeons integrate the objective measures…
- Trial name
- NCT03537976
- Testing
- Static Images and Facial Videos
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Tufts University
Cleft Palate, Cleft Palate, Unilateral, Complete
MRI Assessment of Velopharyngeal Anatomy After Modified Furlow-Buccinator Flap in Late Primary Palate Repair
The goal of this case series study is to learn if magnetic resonance imaging (MRI) can show how well the palate and throat muscles work at rest and during speech after late cleft palate repair.
- Conditions
- Cleft Palate, Cleft Palate, Unilateral, Complete, Cleft Lip, Cleft Alveolus and Cleft Palate, Cleft Palate Repair
- Trial name
- NCT07514091
- Testing
- Modified Furlow Palatoplasty combined with buccinator myomucosal flap
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Cairo University
Cleft Lip and Palate, Cleft Palate
Three-dimensional Cleft Lip and Palate Morphology Prior to One-stage Cleft Repair
This is a prospective observational cohort study of consecutive patients with cleft lip and palate deformity undergoing cleft repair at the Institute of Mother and Child in Warsaw.
- Conditions
- Cleft Lip and Palate, Cleft Palate, Craniofacial Deformity
- Trial name
- NCT04616690
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- University Hospital, Basel, Switzerland